Clinical trials: Gastric Contents
Diabetes
Preoperative Evaluation of Gastric Contents by Antral Ultrasound in Diabetic Patients
Gastric aspiration represents the third cause of perioperative death in France. In scheduled surgery, it can be prevented by preoperative fasting.
- Trial name
- PEGASED (NCT04668651)
- Testing
- antral ultrasound
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nice
Fasting
Gastric Emptying Time After Turkish Breakfast
DETERMINING GASTRIC EMPTYING TIME IN ELDERLY USING ULTRASOUND ASSOCIATED WITH PREOPERATIVE FASTING TIME Background: Gastric contents aspiration is the most crucial complication of general anaesthesia.
- Trial name
- NCT04789785
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Pulmonary Aspiration of Gastric Contents, Adverse Effects in the Therapeutic Use of Other and Unspecified General Anaesthetics
Safety of Gastric Volume Emptying After the Intake of Maltodextrin and Glutamine
Carbohydrates (CHO)-based drinks 2h before the induction of anesthesia are recommended to decrease insulin resistance. The addition of glutamine (GLN) in these beverages may enhance the benefits of CHO alone.
- Conditions
- Pulmonary Aspiration of Gastric Contents, Adverse Effects in the Therapeutic Use of Other and Unspecified General Anaesthetics, Pulmonary Aspiration During Anaesthetic Induction
- Trial name
- NCT01798342
- Testing
- Maltodextrin, Glutamine
- Where
- Brazil
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
Rapid Sequence Induction
Classic and Modified Rapid Sequence Induction for Prevention of Gastric Content Regurgitation
Induction of anesthesia induces a loss of protective upper airway reflexes and is associated with gastric content regurgitation.
- Trial name
- NCT04312425
- Testing
- Modified rapid sequence induction, Classic rapid sequence induction
- Where
- China
- Volunteers
- 8,601 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Positive-Pressure Respiration, Respiratory Aspiration of Gastric Content
Ultrasonographic Comparison of Gastric Volume After Three Modes of Positive Facemask During Induction of Anaesthesia
This study is designed to evaluate the occurrence of gastric insufflation and the critical volume of the stomach after three different modes of positive pressure ventilation during induction (Manual-controlled, volume-controlled…
- Trial name
- UGV (NCT02906267)
- Testing
- Diagnostic ultrasonography of gastric volume
- Where
- France
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Endoscopy, Digestive System, GLP1-R-related Disease
Evaluate the Detection of Retained Gastric Contents and Assess Safety Using the Flower Capsule Endoscopy in Healthy Individuals and GLP-1 Receptor Agonist Users
Clinical Study Overview Feasibility Study Plan (Study 1: Healthy Participants) Study 1- Confirming Flower capsule performance characteristics in detection of retained gastric contents greater than 1.5mL/kg in Healthy volunteers…
- Trial name
- NCT06927401
- Testing
- Flower
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Pulmonary Aspiration of Gastric Contents
Videolaryngoscopy Compared to Direct Laryngoscopy
Videolaryngoscope (Macintosh-type blade) compared with direct laryngoscopy for rapid sequence intubation in the operating room
- Trial name
- LARA (NCT04794764)
- Testing
- McGrath Mac, Macintosh Laryngoscope
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Johannes Gutenberg University Mainz
Gastroparesis
Gastric Ultrasound To Assess Gastric Contents In Patients On Semaglutide Therapy
Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1-RA) such as semaglutide (Ozempic™, Rybelsus™, Wegovy™) were first introduced as a therapeutic agent for type 2 diabetes mellitus but they are being increasingly used to…
- Trial name
- GUST (NCT06292065)
- Testing
- Point-of-care gastric ultrasound
- Where
- Belgium
- Volunteers
- 88 people
- Sponsor
- Nils Vlaeminck
Anesthesia, Surgical Procedure, Unspecified
Ultrasound Assessment of Gastric Content for Semi Emergency Surgery
Aspiration of gastric content is a rare but serious complication of anesthesia. In this context, preoperative fasting for elective surgery is well defined.
- Trial name
- ECHO-GAST (NCT02386787)
- Testing
- Ultrasonography
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Gastric Volume
Identification of Changes in Gastric Volume and Content by Ultrasound Before and After Chewing Gum
To identify by ultrasound the possible changes in gastric volume and content after chewing gum for an hour in volunteers with complete fasting (more than 8 hours).
- Trial name
- NCT02852863
- Testing
- Gum
- Where
- Colombia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Fundación Santa Fe de Bogota
Pneumonia
Venticute in Patients With Pneumonia or Aspiration of Gastric Contents and Intubation/Ventilation/Oxygenation Impairment (BY2001/M1-007)
Study to demonstrate that administration of Venticute increases survival of patients with pneumonia or aspiration of gastric contents leading to intubation, mechanical ventilation, and severe oxygenation impairment.
- Trial name
- NCT00074906
- Testing
- Venticute
- Where
- 92 sites in Australia, Austria and 15 more
- Volunteers
- 1,200 people
- Sponsor
- Takeda
GERD
Mechanisms Preventing Pharyngeal Reflux
The overall goal is to define and characterize the manometric characteristics of UES incompetence associated with objectively documented pharyngeal reflux. The investigators will use endoscopic reflux detection as gold standard.
- Trial name
- NCT05696184
- Testing
- Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy, Slow and rapid intra-esophageal infusion
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Diabetes Mellitus, Type 2, Overweight
A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus
The purpose of this study is to evaluate how fasting and stopping the use of tirzepatide affects the amount of food and drink that stays in the stomach after a meal.
- Conditions
- Diabetes Mellitus, Type 2, Overweight, Obesity
- Trial name
- NCT07299084
- Testing
- Tirzepatide
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Eli Lilly and Company
Gastroparesis
Ultrasound Assessment of Gastric Contents in Fasted Surgical Patients With Previous Subtotal Gastrectomy
Investigators assess the gastric contents by ultrasonography in fasted patients with previous subtotal gastrectomy.
- Trial name
- NCT03802006
- Testing
- Ultrasound assessment of gastric content
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Seoul National University Hospital
Aspiration; Gastric Contents, Anesthesia
An Evaluation of a Liberal Hydration Regimen Before Elective Caesarean Section Using Beside Gastric Ultrasound
The aim of this study is to compare the residual gastric volumes in non-labouring parturients prior to elective Caesarean delivery when fully fasted as per European Society of Anaesthesia pre-operative fasting guidelines against…
- Trial name
- NCT05783427
- Testing
- liberal hydration
- Where
- Ireland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Coombe Women and Infants University Hospital
Gastric Contents
Does the Menstrual Phase Affect Gastric Emptying? Prospective, Observational Study
This prospective observational study aimed to evaluate the relationship between menstrual phase cycles and gastric emptying in female volunteers of reproductive age.
- Trial name
- MAGUSG (NCT05407558)
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Pregnancy, Respiratory Aspiration of Gastric Contents
Gastric Emptying Following an Oral Carbohydrate Load in Women Admitted for Elective Cesarean Delivery
Because of the risk of pulmonary aspiration, patients are asked to comply with the fasting guidelines when they are scheduled for an elective cesarean section.
- Trial name
- NCT03593980
- Testing
- Cranberry juice
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Healthy Volunteer
Relative Bioavailability and Drug-drug Interaction Study With MT-7117 and a Proton Pump Inhibitor
An open label, multicentre, randomised, 2-cohort, sequential and crossover study to assess the relative oral bioavailability of MT-7117 higher content tablets versus MT-7117 lower content tablets and the pharmacokinetics of…
- Trial name
- MT-7117 BA DDI (NCT03688022)
- Testing
- MT-7117, PPI, Acidic beverage
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tanabe Pharma America, Inc.
Pneumonia, Aspiration, Gastric Content
Point-of-care Gastric Ultrasound for Fracture Surgery
Although there are fasting guidelines offered by the American Society of Anesthesiology (ASA) for managing preoperative patient assessment, some patients may need to be more cautious about the risk of aspiration.
- Conditions
- Pneumonia, Aspiration, Gastric Content, Fractures, Bone
- Trial name
- NCT05728242
- Testing
- Gastric ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Haseki Training and Research Hospital
Pulmonary Aspiration of Gastric Contents
Gastric Content After 6 vs 4 Hours of Preoperative Fasting in Children
The primary objective of the study is to compare the risk of increased stomach contents after tube feeding (Enteral feeding) 6 and 4 hours before anesthesia using antrum measured by ultrasound.
- Trial name
- ENGUS (NCT05695066)
- Testing
- Preoperative fasting instruction
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- Uppsala University Hospital