Clinical trials: Gastric Contents
Aspiration of Gastric Contents, Gastric Emptying
The Effect of Intravenous Erythromycin on Gastric Emptying in Non-fasted Patients Before Emergency Total Anesthesia
In this study the investigators want to investigate the effect of a short intravenous infusion of Erythromycine on gastric emptying on patients considered "full stomac" and scheduled for Emergency operation.
- Trial name
- NCT00827216
- Testing
- Erythromycin
- Where
- Switzerland
- Volunteers
- 132 people
- Sponsor
- University Hospital, Geneva
Respiratory Aspiration, Pregnancy
Gastric Ultrasound in Pregnant Women at Term
Solid food or fluid residue in the stomach is always a major concern when patients need medical procedures under sedation or general anesthesia, due to the high risk of pulmonary aspiration of the stomach contents.
- Trial name
- NCT01564030
- Testing
- Empty, Fluid, Solid
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Aspiration
Routine Point of Care Ultrasound (POCUS) Assessment of Antral Gastric Contents in Traumatic Surgical Patients for Prevention of Aspiration Pneumonitis
Pulmonary aspiration of gastric contents is uncommon in the elective, surgical populations, but highly prevalent in trauma patients who requires emergency surgery as trauma impair gastric motility and emptying.1 Presence of…
- Trial name
- NCT04083677
- Testing
- SONAR
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Anesthesia, Sedation
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful.
- Conditions
- Anesthesia, Sedation, Monitored Anesthesia Care, Procedure
- Trial name
- MACS (NCT07022951)
- Testing
- Preoperative fasting
- Where
- United States
- Volunteers
- 1,200,000 people
- Sponsor
- Massachusetts General Hospital
Respiratory Aspiration of Gastric Contents
Positioning and Gastric Aspiration in Ventilated Premature Infants
Gastro-esophageal reflux and aspiration is a common problem in premature infants receiving mechanical ventilation. Pepsin measured in tracheal aspirate (TA) emerged as a specific marker for aspiration.
- Trial name
- NCT02016651
- Testing
- Right side position
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Healthy
Factors That Determine the Responses to Food Ingestion: Protein Load
Aim: to determine to what extent meal composition influences postprandial sensations. Experimental design: randomized cross-ower study comparing the responses to a high protein (47.3% protein, 39.4% carbohydrates, 13.3% lipids)…
- Trial name
- NCT06139237
- Testing
- High-protein supplement, Balanced supplement
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Metabolism, Trauma
ImpACt of Very High Protein Content Enteral nUtrition Formulas on Critically Ill MUltipLe trAuma paTiEnts
This prospective observational randomized study aims to determine energy, protein intake and gastrointestinal tolerance while using enteral nutrition formulas with very high protein content and enteral nutrition formulas with…
- Conditions
- Metabolism, Trauma, Nutritional Deficiency, Protein Malnutrition
- Trial name
- ACCUMULATE (NCT05647135)
- Testing
- Medical food
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition
Pre-op Gastric Emptying
Residual Gastric Content and GLP-1
Studies have shown that even following the fasting guideline, patients on GLP-1 still have residual gastric content which increases their risk of aspiration during anesthesia.
- Trial name
- NCT06814080
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Gastric Emptying, Diabetes
Gastric Ultrasound in Diabetic Patients
The American Society of Anesthesiologists (ASA) does not specify a fasting period for patients with certain comorbidities, such as diabetes, for elective surgery, and does not make a separate recommendation for surgery.
- Conditions
- Gastric Emptying, Diabetes, Ultrasound
- Trial name
- NCT06195488
- Testing
- Gastric ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Appendectomy
Ultrasound Assessment of Gastric Content Before Anesthesia for Appendectomy
Performing anesthetic induction for appendicectomy has two main risks : first aspiraion of gastric content causing pneumonia. Otherwise, anaphylactic risk to drugs used during anesthetic induction.
- Trial name
- EGASTA (NCT02983175)
- Testing
- ultrasound assessment of gastric content
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Fasting, Pediatric ALL
Gastric Content Ultrasound Monitoring Prior to Extubation in Critically Ill Children
Nearly half of critically ill children are intubated and enterally fed according to recent guidelines. However, no evidence-based recommendation are available regarding fasting times prior to extubation.
- Conditions
- Fasting, Pediatric ALL, Aspiration
- Trial name
- GastrExtub (NCT05181904)
- Testing
- Gastric ultrasound
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Hospices Civils de Lyon
Variation of the Antral Area After Cigarettes Smoking or Not
Cigarette and Gastric Contents
The aims of this cross over prospective study are to demonstrate that smoking two cigarettes do not change the gastric contents and volume in fasting volunteers.
- Trial name
- NCT02080598
- Testing
- 2 cigarettes in 15 minutes
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lionel Bouvet
Respiratory Aspiration, Pregnancy
Quantitative Ultrasound Assessment of Gastric Volume in Pregnant Women at Term
Solid food or fluid residue in the stomach is always a major concern when patients need medical procedures under sedation or general anesthesia, due to the high risk of pulmonary aspiration of the stomach contents.
- Trial name
- NCT01980108
- Testing
- water
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Residual Gastric Contents, Polyethylene Glycol
Effect of Miralax NPO Time on Residual Gastric Volumes and Bowel Preparation
The goal of this clinical trial is to assess differences in residual gastric volumes after stopping Miralax ingestion at different time points (2, 4, 6 hours) prior to anesthesia induction and compare it to the control (current…
- Trial name
- NCT07616908
- Testing
- Stopping Miralax ingestion 4 hours prior to anesthesia induction, Stopping Miralax ingestion 6 hours prior to anesthesia induction, Stopping Miralax ingestion 2 hours prior to anesthesia induction
- Volunteers
- 200 people
- Sponsor
- Stanford University
Postoperative Ileus, Postoperative Nausea
Assessing Gastric Motility and Distention in Postoperative Gastrointestinal Surgery Using Bedside Gastric Ultrasound: Predicting Risk of Aspiration Pneumonia, Ileus, Return of Bowel Function
Point-of-care gastric ultrasound will be used to measure stomach contents postoperative in patients who underwent colorectal surgery.
- Conditions
- Postoperative Ileus, Postoperative Nausea, Postoperative Complications, Postoperative Nausea and Vomiting
- Trial name
- NCT04747691
- Testing
- Bedside gastric ultrasound
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eric Schwenk
Enteral Nutrition Intolerance in Critically Ill Patients
Reaching a Caloric Goal Using a Gastric Sonar Versus Aspiration of Gastric Contents in Critically Ill Patients Receiving Nasogastric Enteral Nutrition
Enteral nutrition intolerance, manifested in delayed gastric emptying and high gastric residual, is a common problem in critically ill patients in intensive care, with adverse consequences on patients' outcomes.
- Trial name
- NCT06557629
- Testing
- Ultrasound assessment
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Obesity
MRI Based Study to Assess Brain-gut Axis in Obesity
The mechanism of neural communication between the brain and gut in the regulation of food intake is complex and not fully understood.
- Trial name
- BGImaging (NCT05437653)
- Testing
- Nutritional Drink A, Nutritional Drink B
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Pneumonia, Aspiration, Anesthesia
Evaluation of Gastric Content of Volunteers Fasting and Using Semaglutide: an Observational and Cross-sectional Study
Medicines with peptide-1 receptor agonist action similar to glucagon (GLP-1) are a modern therapeutic option for obesity and diabetes mellitus.
- Trial name
- NCT06154486
- Testing
- semaglutide use
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital Israelita Albert Einstein
Mechanical Ventilation Complication, Ventilator Associated Pneumonia
Effects of Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents
The purpose of study is to determine effects of three different ET cuff pressure control on microaspiration of the stomach contents.
- Conditions
- Mechanical Ventilation Complication, Ventilator Associated Pneumonia, Nursing Caries, Aspiration, Respiratory
- Trial name
- NCT04061083
- Testing
- Smart Cuff Manager, Manometer
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Afyonkarahisar Health Sciences University
Non-fasting Patients, Rapid Sequence Intubation
Preoperative Presence of Gastric Content in Non-fasting Patients - an Ultrasound Study
Using bedside ultrasound, the investigators will examine gastric content in non-fasting patients assigned to rapid sequence intubation (RSI). The procedure will be done immediately before intubation.
- Conditions
- Non-fasting Patients, Rapid Sequence Intubation, Anesthesia Intubation Complication
- Trial name
- NCT03685435
- Testing
- Bedside ultrasound
- Where
- Norway
- Volunteers
- 72 people
- Sponsor
- University Hospital, Akershus