Clinical trials: Gastric Diseases
Gastric Cancer
Pre-rehabilitation in Neoadjuvant Patients With Gastric Cancer
In this study, patients with traditional neoadjuvant gastric cancer were used as controls to explore whether the triple pre-rehabilitation interventions of exercise, nutrition and psychology during the neoadjuvant period before…
- Trial name
- NCT05445401
- Testing
- Pre-rehabilitation, Standard medical care
- Volunteers
- 30 people
- Sponsor
- The First Hospital of Jilin University
Gastric Ulcer
Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Gastric Ulcer
To demonstrate non-inferiority of CJ-12420 to lansoprazole 30 mg capsule in terms of therapeutic efficacy, and to confirm safety of CJ-12420, after once daily oral administration of CJ-12420 50 mg, 100 mg or Lansoprazole 30 mg…
- Trial name
- NCT02761512
- Testing
- CJ-12420 50 mg QD, CJ-12420 100 mg QD, Lansoprazole 30 mg QD
- Where
- 2 sites in South Korea
- Volunteers
- 306 people
- Sponsor
- HK inno.N Corporation
Early Gastric Cancer
Screening for Early Gastric Cancer in Shaanxi Province
This study collect the relevant data of local residents over 20 years old in 11 regions of Shaanxi Province, The basic information of the subjects was collected by filling in the questionnaire, and serum helicobacter pylori…
- Trial name
- NCT05291728
- Where
- China
- Volunteers
- 12,500,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Gastric Emptying, Diabetes
Gastric Ultrasound in Diabetic Patients
The American Society of Anesthesiologists (ASA) does not specify a fasting period for patients with certain comorbidities, such as diabetes, for elective surgery, and does not make a separate recommendation for surgery.
- Conditions
- Gastric Emptying, Diabetes, Ultrasound
- Trial name
- NCT06195488
- Testing
- Gastric ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Gastric Cancer
Gastrectomy With or Without Drainage (ADiGe)?
Prophylactic use of anastomotic drain in upper gastrointestinal surgery has been questioned in the last 15 years but only small studies have been conducted.
- Trial name
- ADiGe (NCT04227951)
- Testing
- Avoid drain placement, Drain placement
- Where
- 11 sites in Italy
- Volunteers
- 404 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Scleroderma, Dysphagia
Functional Luminal Imaging Probe (FLIP) Topography Use in Patients With Scleroderma and Trouble Swallowing
FLIP topography has been FDA cleared to evaluate a variety of esophageal conditions, but has never been evaluated in patients with scleroderma.
- Conditions
- Scleroderma, Dysphagia, GERD - Gastro-Esophageal Reflux Disease
- Trial name
- NCT03270722
- Testing
- FLIP topography, Upper Endoscopy
- Where
- United States
- Sponsor
- Stanford University
Gastric Cancer, Esophageal Adenocarcinoma
Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies
The investigators propose to evaluate the safety of drug combinations in patients with advanced gastroesophageal cancer and other gastrointestinal (GI) malignancies.
- Conditions
- Gastric Cancer, Esophageal Adenocarcinoma, Hepatocellular Carcinoma, Colorectal Cancer
- Trial name
- CAMILLA (NCT03539822)
- Testing
- Cabozantinib, Durvalumab, Tremelimumab
- Where
- 2 sites in United States
- Volunteers
- 117 people
- Sponsor
- Anwaar Saeed
Helicobacter Pylori, Atrophic Gastritis
Helicobacter Pylori, Atrophic Gastritis and Intestinal Metaplasia Registry and Prospective Study
Since much is unknown about factors that lead to progression of the pre-neoplastic lesions and cancer. In addition, there is ongoing debate on the optimal surveillance intervals and techniques.
- Conditions
- Helicobacter Pylori, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT05053945
- Testing
- Esophagogastroduodenoscopy
- Where
- 2 sites in Hong Kong
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cortisol
Effect of MIST on Esophageal Sensitivity: Pilot Study
Influence of placing the esophageal probe on the cortisol response. Number of cortisol (non)responders and association of heart rate and subjective perception of stress with cortisol levels.
- Trial name
- PilotMIST (NCT05760872)
- Testing
- Placing esophageal probe
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity, Morbid
Impact of the Preservation of the Gastric Antrum in the Technique of Sleeve Gastrectomy for the Treatment of the Morbid Obesity
The bariatric surgery is recognized, at present, as the only effective therapeutic for the patients with morbid obesity. Two surgical procedures (said restrictive) are considered as consensual: the adjustable calibrated…
- Trial name
- QUALISLEEVE (NCT01550601)
- Testing
- bariatric surgery
- Where
- France
- Volunteers
- 346 people
- Sponsor
- University Hospital, Montpellier
Gastric Cancer
Phase II Study of ABI-007 for Gastric Cancer
The purpose of this study is to evaluate the efficacy and safety of tri-weekly ABI-007 for recurrence or unresectable gastric cancer patients who have received one prior regimen containing fluoropyrimidine and developed disease…
- Trial name
- NCT00661167
- Testing
- ABI-007
- Where
- 10 sites in Japan
- Volunteers
- 56 people
- Sponsor
- Taiho Pharmaceutical Co., Ltd.
Stomach Neoplasms
Study of Nimotuzumab and Irinotecan as Second Line With Recurrent or Metastatic Gastric Adenocarcinoma
The trial aims to evaluate the efficacy and safety of adding nimotuzumab to irinotecan after failure of first-line treatment in recurrent or metastatic gastric adenocarcinoma with overexpression of EGFR, and search for the…
- Trial name
- NIEGA (NCT03400592)
- Testing
- Irinotecan, nimotuzumab
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Peking University
Obesity, Morbid, Postoperative Pain
Study of the Effect of the Drug Gabapentin on Postoperative Pain and Incidence of Postoperative Nausea and Vomiting
The purpose of this research study is to evaluate the drug gabapentin (Neurontin®) for its ability to reduce postoperative pain, the need for morphine-like pain medication, and the severity and frequency of postoperative nausea…
- Conditions
- Obesity, Morbid, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- NCT00886236
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Medical University of South Carolina
Chronic Atrophic Gastritis
The Study of Chinese Medicine for the Treatment of Chronic Atrophic Gastritis
The purpose of this study is to evaluate efficacy of Chinese medicine treatment for chronic atrophic gastritis. It is a multi-center, randomized, placebo-controlled trial.
- Trial name
- NCT02955134
- Testing
- Talcid®, Chinese medicine prescription, Compound Azimtamide Entieric-coated Tablets
- Where
- 13 sites in China
- Volunteers
- 468 people
- Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences
Motility Disorders
Pilot of AbStats /AEGIS System for Detecting Motility Abnormalities
When compared to existing analyses: manometry, Smart Pill and lactulose breath testing, external Acoustic Esophago-Gastro-Intestinal Surveillance (AEGIS) may identify unique audible patterns characteristic of features of…
- Trial name
- AEGIS (NCT02233270)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cedars-Sinai Medical Center
Neoplasms, Gastrointestinal Tract
Lapatinib in Combination With Weekly Paclitaxel in Patients With ErbB2 Amplified Advanced Gastric Cancer
EGF104578 is two-part study (Pilot part/Randomized part).Pilot part is designed to find the optimal (best) doses of lapatinib and paclitaxel when given together,Randomized part is designed to evaluate the overall survival in…
- Trial name
- NCT00486954
- Testing
- Lapatinib, Paclitaxel
- Where
- 17 sites in China, Japan and 2 more
- Volunteers
- 273 people
- Sponsor
- GlaxoSmithKline
Gastrectomy, Oesophagectomy
Metabolic Consequences of Gastrointestinal Surgery
Surgery on the gastrointestinal (GI) tract results in profound changes to the metabolic profile. This is well described, including the rapid resolution of diabetes seen after bariatric surgery.
- Conditions
- Gastrectomy, Oesophagectomy, Dumping Syndrome, Hypoglycaemia
- Trial name
- MaS (NCT02836353)
- Testing
- Somatostatin, Rifaximin
- Where
- United Kingdom
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Gastric Cancer, Peritoneal Metastases
HIPEC Combined Gastrectomy in Patients With Advanced Gastric Cancer Received Neoadjuvant Chemotherapy
Patients with stage cT3-4N+M0 gastric cancer were recommended to receive neoadjuvant chemotherapy before radical surgery in terms of the eradication of micrometastasis in addition to local control, higher compliance with…
- Trial name
- NCT05300945
- Testing
- HIPEC
- Volunteers
- 200 people
- Sponsor
- Zhixin Cao
Gastrointestinal Cancers
DPD Guided 5-FU Precision Treatment in Gastro-intestinal Cancer Patients
Rationale: Fluorouracil (5-FU) are broadly used in chemotherapeutic regimens for the treatment of cancers. Dihydropyrimidine dehydrogenase (DPD) is a major enzyme in the 5-FU metabolism pathway.
- Trial name
- COMBIGaPP (NCT06782022)
- Testing
- 5-Fluoro-Uracil
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Jan Gerard Maring
Gastric Cancer, Surgery
Phase III Randomized Trial of Adjuvant XP Chemotherapy and XP/RT for Resected Gastric Adenocarcinoma
The objective of the trial is to compare disease-free survival between adjuvant capecitabine/cisplatin alone vs capecitabine/cisplatin with radiotherapy (chemoradiation) in curatively resected gastric cancer patients.
- Trial name
- NCT00323830
- Testing
- Capecitabine, cisplatin, Radiotherapy (+/-)
- Where
- South Korea
- Volunteers
- 458 people
- Sponsor
- Samsung Medical Center
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