Clinical trials: Gastric Intestinal Metaplasia
Gastric Intestinal Metaplasia, Treatment
RFA for GIM Treatment
Use radiofrequency ablation (RFA) for Gastric intestinal metaplasia (GIM) treatment.
- Conditions
- Gastric Intestinal Metaplasia, Treatment, Radio-frequency Ablation
- Trial name
- NCT04348266
- Testing
- Radiofrequency ablation (RFA)
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Gastric Intestinal Metaplasia, Gastric Cancer
RCT: WLE vs. NBI in Upper Gastrointestinal Endoscopy
It is recognized that gastroscopy can miss intestinal metaplasia, dysplasia and early gastric cancer. This could conceivably be due to the fact that these lesions may only present as subtle mucosal changes on conventional white…
- Trial name
- NCT01945177
- Testing
- narrow band imaging, white light endoscopy
- Where
- Singapore
- Volunteers
- 600 people
- Sponsor
- Changi General Hospital
Gastric Cancer, Atrophic Gastritis
AG & IM in CA Stomach Protocol
This is a multi-center prospective case control study aiming to compare different methods of risk stratification models in predicting the risk of gastric cancer development.
- Conditions
- Gastric Cancer, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT04184960
- Testing
- Gastroscopy and gastric biopsies
- Where
- 4 sites in Hong Kong, Japan and 2 more
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Gastritis, Atrophic, Helicobacter Pylori Infection
Diagnosis of Gastritis, H. Pylori Infection and Atrophic Gastritis in Dyspeptic Patients
Gastric cancer is the third most common cause of cancer-related death worldwide (1). Upper endoscopy is necessary to detect neoplastic macroscopic features at an early stage, but subtle abnormalities in the gastric mucosa are…
- Conditions
- Gastritis, Atrophic, Helicobacter Pylori Infection, Intestinal Metaplasia, Gastritis
- Trial name
- NCT04296513
- Testing
- High-Definition white light endoscopy., High-definition magnification with digital chromoendoscopy.
- Where
- Ecuador
- Volunteers
- 150 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Gastric Microbiota, Non-atrophic Gastritis
Difference of Gastric Microbiota in the Process of Correa's Model.
Helicobater pylori plays an important role in the development of gastric cancer. Eradication therapy can reducing the morbidity of gastric cancer, but can't totally prevent it especially when atrophy and more serious precancerous…
- Conditions
- Gastric Microbiota, Non-atrophic Gastritis, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT02833363
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shandong University
Cancer
Gene Therapy in Treating Patients With Cancer
RATIONALE: Inserting a gene that has been created in the laboratory into a person's white blood cells may make the body build an immune response to kill cancer cells.
- Trial name
- NCT00004178
- Testing
- therapeutic autologous lymphocytes
- Where
- United States
- Sponsor
- Roger Williams Medical Center
Intestinal Metaplasia
Confocal Laser Endomicroscopy for the Detection of Gastric Intestinal Metaplasia: a Randomized Controlled Trial
The purpose of this study is to assess whether confocal laser endomicroscopy can reduce the biopsy number needed per patient for the detection of gastric intestinal metaplasia without the loss of corresponding diagnostic yield.
- Trial name
- NCT01024621
- Testing
- Endomicroscope, Standard endoscopy
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Shandong University
Gastric Cancer, Intestinal Metaplasia
Prediction of Gastric Cancer in Intestinal Metaplasia and Atrophic Gastritis
The primary objectives of this study are: To identify clinical or histological factors associated with gastric cancer development in patients with IM and AG To establish a machine learning algorithm for prediction of future…
- Conditions
- Gastric Cancer, Intestinal Metaplasia, Atrophic Gastritis
- Trial name
- GIMA (NCT04840056)
- Where
- Hong Kong
- Volunteers
- 1,300 people
- Sponsor
- Chinese University of Hong Kong
Stomach Cancer
Prognosis and Risk Factors of Gastric Cancer in Patients With Intestinal Metaplasia
This prospective cohort study aims to assess the incidence of gastric cancer in patients with intestinal metaplasia in body of stomach or angular incisure.
- Trial name
- GASTRIMED (NCT02325323)
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrophic Gastritis
Usefulness of Serum Pepsinogen and Gastrin as the Predictive Biomarker of Atrophic Gastritis, Intestinal Metaplasia and Gastric Cancer in Korea
It is well-known that atrophic gastritis is a major risk factor for gastric cancer, which leads to variations in the serum levels of gastrin, pepsinogen (PG) I, and PGII.
- Trial name
- NCT02184910
- Testing
- pepsinogen and gastrin
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Barrett's Esophagus, Intestinal Metaplasia
Prevalence of Dysplasia of the Gastric Cardia
We propose a tissue sample collection study for patients at UNC who have undergone or will undergo radiofrequency ablation therapy for Barrett's Esophagus (BE) or intramucosal adenocarcinoma as part of routine medical care.
- Conditions
- Barrett's Esophagus, Intestinal Metaplasia, Intramucosal Adenocarcinoma
- Trial name
- NCT01787864
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- University of North Carolina, Chapel Hill
Gastric Intestinal Metaplasia
Metformin Efficacy and Safety for Gastric Intestinal Metaplasia
Gastric intestinal metaplasia significantly increases the risk of gastric cancer. Metformin, a biguanide, which is widely used for treating diabetes mellitus, has recently been suggested to have a suppressive effect on…
- Trial name
- NCT05288153
- Testing
- Metformin, Folate
- Where
- 2 sites in China
- Volunteers
- 140 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastric Intestinal Metaplasia
Magnified Intelligence Chromoendoscopy Plus Probe-based Confocal Laser Endomicroscopy for Gastric Intestinal Metaplasia Diagnosis
Magnified intelligence chromoendoscopy (FICE) plus probe-based confocal laser endomicroscopy (pCLE) for Gastric Intestinal Metaplasia (GIM) diagnosis: a feasibility trial Research Question: Is confocal endomicroscope feasible to…
- Trial name
- NCT01489397
- Testing
- Confocol laser endomicroscopy
- Where
- Thailand
- Volunteers
- 45 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Gastric Intestinal Metaplasia, Gastric Cancer
Microbiome Analysis in Gastric Intestinal Metaplasia and in Gastric Cancer and Subtypes Correlation
The aim of the study will be to analyze the microbiome in the blood and stomach in patients with intestinal metaplasia (IM) and / or gastric cancer (GC).
- Conditions
- Gastric Intestinal Metaplasia, Gastric Cancer, Microbiome
- Trial name
- NCT04365946
- Testing
- Gastroscopy
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ioannina
Gastric Intestinal Metaplasia
The Efficacy of Severe Whitening and Delayed Fading in Acetic Acid-enhanced Endoscopy for Diagnosing Gastric Intestinal Metaplasia
Investigators found that the degree and the duration of aceto-whitening differed between gastric intestinal metaplasia(GIM) and the surrounding normal mucosa: the area of GIM showed a severe degree of aceto whiteness and the…
- Trial name
- NCT02806115
- Testing
- acetic acid-enhanced endoscopy, Acetic Acid, endoscope
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shandong University
Intestinal Metaplasia
Sensitivity of Targeted Biopsy Within Sydney Protocol for GIM
Sensitivity of Targeted Biopsy Within Sydney Protocol by Using Narrow Band Imaging for Extensive Gastric Intestinal Metaplasia Diagnosis Objective: The aim of this study is to evaluate the sensitivity of targeted biopsy within…
- Trial name
- NCT04331951
- Testing
- Targeted biopsy within Sydney protocol
- Where
- Thailand
- Volunteers
- 105 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Helicobacter Pylori Infection, Early Gastric Cancer
Effects of H. Pylori Eradication on the Gastric Preneoplastic Lesion and Neoplasm After ESD
This study evaluates whether Helicobacter pylori eradication improves precancerous lesions including glandular atrophy and intestinal metaplasia as well as metachronous cancers or dysplasias after endoscopic mucosal resection for…
- Conditions
- Helicobacter Pylori Infection, Early Gastric Cancer, Endoscopic Resection
- Trial name
- NCT02407119
- Testing
- 7 day H.pylori eradication Omeprazole or Rabeprazole, Clarithromycin, Amoxicillin
- Where
- South Korea
- Volunteers
- 470 people
- Sponsor
- National Cancer Center, Korea
Stomach Neoplasms, Atrophic Gastritis
OLGA and OLGIM Stage System for Gastric Cancer
To validate OLGA and OLGIM staging system with serum pepsinogen for estimating GC risk according to Lauren's histologic classification in South Korea.
- Conditions
- Stomach Neoplasms, Atrophic Gastritis, Intestinal Metaplasia
- Trial name
- NCT03380052
- Where
- South Korea
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Gastric Cancer
Efficacy Study of Helicobacter Pylori Eradication in Patients Undergoing Subtotal Gastrectomy for Gastric Cancer
Helicobacter pylori (H. pylori) is associated with gastric cancer in epidemiological studies.Gastric atrophy and intestinal metaplasia caused by H. pylori are considered as precancerous lesions, but whether H.
- Trial name
- NCT01002443
- Testing
- Helicobacter pylori eradication
- Where
- South Korea
- Volunteers
- 190 people
- Sponsor
- National Cancer Center, Korea
Gastric Cancer, Gastric (Stomach) Cancer
Gastric Cancer Endoscopic Screening in an Intermediate-risk Country - ROGCAS, a Dual-centre Pilot Program
Endoscopic screening of gastric cancer combined with screening colonoscopy
- Conditions
- Gastric Cancer, Gastric (Stomach) Cancer, Atrophic Gastritis, Intestinal Metaplasia of Gastric Mucosa
- Trial name
- ROGCAS (NCT06316882)
- Testing
- Screening endoscopy
- Where
- Portugal
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- Unidade Local De Saúde Do Norte Alentejano