Clinical trials: Gastric Resection
Morbid Obesity
Transmitted Light Tissue Thickness Analysis (TiLTT)
To assess gastric wall thickness using transmitted light intensity.
- Trial name
- TiLLT (NCT02749201)
- Testing
- Gastrisail
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Maimonides Medical Center
Bariatric Surgery Candidate
Pilot Study for Zoledronic Acid to Prevent Bone Loss After Bariatric Surgery
This study evaluates whether zoledronic acid can prevent the high bone turnover that occurs after Roux-en-Y Gastric Bypass (RYGB) and sleeve gastrectomy (SG) surgery.
- Trial name
- NCT03424239
- Testing
- Zoledronic Acid, Calcium citrate + vitamin D, Vitamin D3
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Massachusetts General Hospital
Laparoscopic Sleeve Gastrectomy, Subcostal Transversus Abdominis Plane Block
Unilateral TAP Block for Laparoscopic Gastric Sleeve Surgery
The study team will be assessing if the unilateral subcostal transversus abdominis plane (TAP) block can decrease pain and improve outcomes following laparoscopic sleeve gastrectomy surgeries.
- Trial name
- NCT03856788
- Testing
- Saline, Bupivacaine
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Impaired Renal Function
Effects of Obesity Surgery on Renal Function
Increasing risk of impaired renal function as a result of obesity is well known. Early data has postulated that weight loss might improve kidney function, but the evidence is rather limited due to the difficulties in measuring…
- Trial name
- NCT01507350
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- Imperial College London
Neuromuscular Blockade
Effectiveness of Deep Versus Moderate Neuromuscular Blockade
The aim of this study is to evaluate the influence of depth of neuromuscular blockade during laparoscopic gastrectomy on postoperative pain in surgical patients allocated randomly to either deep or moderate neuromuscular blockade…
- Trial name
- NCT03266419
- Testing
- Deep NMB using rocuronium, Moderate NMB using rocuronium
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Gastric Cancer
Propofol EC50 for Inducing Loss of Consciousness in General Combined Epidural Anesthesia
The beneficial of perioperative usage of thoracic epidural anesthesia and analgesia in various thoracic and upper abdominal surgery are well studied.
- Trial name
- NCT05124704
- Testing
- 5-8ml 0.375% ropivacaine, 5-8ml normal saline
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wang Jiangling
Obesity, Pain, Postoperative
Laparoscopic TAP Block for Sleeve Gastrectomy: Does Timing Matter
The goal of this study is to investigate whether an early intraoperative transverse abdominis plane block (TAP block) will provide superior analgesia to a late intraoperative TAP block.
- Trial name
- NCT04787367
- Testing
- TAP block
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Arthur Carlin
Obesity
Endostapler Sleeve Gastrectomy Study
The goal of this prospective, post-market study is to measure AEON™ Endostapler performance for laparoscopic sleeve gastrectomy surgery versus the Endo GIA™ Reloads with Tri-Staple™ Technology from Medtronic.
- Trial name
- NCT04617574
- Testing
- AEON Endostapler, Endo GIA Reloads with Tri-Staple Technology
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lexington Medical Inc.
Carcinoma, Squamous Cell, Adenocarcinoma of the Esophagus and Gastric Cardia
Neoadjuvant Chemotherapy Versus Radiochemotherapy for Cancer of the Esophagus or Cardia
The purpose of this randomized study is to clarify if neoadjuvant radiochemotherapy gives a higher degree of complete histological response than neoadjuvant chemotherapy before surgery in patients undergoing treatment for cancer…
- Trial name
- NeoRes (NCT01362127)
- Testing
- Chemotherapy, Radiochemotherapy
- Where
- Sweden
- Volunteers
- 181 people
- Sponsor
- Karolinska University Hospital
Gastric Cancer, Dumping Syndrome
Gastrectomy, Eating Behaviour and GLP-1
Patients who have undergone gastrectomy (removal of the stomach) to treat or prevent cancer are known to have a significantly reduced quality of life. To date, there is very little information on the physiological causes of this.
- Trial name
- NCT02971631
- Testing
- Exendin 9-39
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Morbid Obesity
Gastric Procedures for Obesity
This is a prospective case series study; all morbidly obese patients that need surgical management in Royal Alexandra Hospital will be provided 3 surgical options: Laparoscopic Sleeve Gastrectomy (LSG), laparoscopic Roux-en-Y…
- Trial name
- NCT01026181
- Volunteers
- 150 people
- Sponsor
- University of Alberta
GERD, Gastroesophageal Reflux Disease
LINX Reflux Management System in Subjects With GERD Who Have Previously Undergone a Laparoscopic Sleeve Gastrectomy
The purpose of this study is to evaluate the LINX device in patients who have previously undergone laparoscopic sleeve gastrectomy (LSG) for obesity and have chronic gastroesophageal reflux disease (GERD).
- Trial name
- RELIEF (NCT02429830)
- Testing
- LINX device
- Where
- 12 sites in United States
- Volunteers
- 30 people
- Sponsor
- Torax Medical Incorporated
Ileus, Gastro-Intestinal Disorder
A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection
The purpose of this study is to evaluate the safety and efficacy of LB1148 in subjects undergoing planned bowel resection.
- Trial name
- INTEGRITY (NCT05470387)
- Testing
- LB1148
- Where
- 23 sites in United States
- Volunteers
- 23 people
- Sponsor
- Palisade Bio
Gastric Adenocarcinoma, Esophagogastric Junction
Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology
Background: Gastric cancer is a common and serious cancer. Standard treatment is chemotherapy drugs. Researchers want to see if a new treatment helps.
- Conditions
- Gastric Adenocarcinoma, Esophagogastric Junction, Gastric Cancer
- Trial name
- NCT03092518
- Testing
- Surgery, Cisplatin, Mitomycin C
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- National Cancer Institute (NCI)
Morbid Obesity
Laparoscopic Sleeve Gastrectomy With Endoscopic Visualization
The main objective of this trial is to evaluate endoscopic visualization during a laparoscopic sleeve gastrectomy (LSG) procedure using an endoscope inserted transvaginally through a new device called a Steerable Flex Trocar…
- Trial name
- NCT00911989
- Testing
- NOTES toolbox
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Ethicon Endo-Surgery
Morbid Obesity
Sleeve Gastrectomy Outcomes With Different Stapling Devices
Sleeve gastrectomy is now the most commonly performed bariatric surgery. While many studies have evaluated factors that may minimize post-operative hemorrhage and staple-line leak, the investigators are unaware of any studies…
- Trial name
- NCT02731079
- Testing
- Covidien iDrive, Ethicon Echilon
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Edna Rath
Gastrectomy, Obesity
Endoscopic vs. Suction Device Calibration in Sleeve Gastrectomy
This study aims to compare the difference in staple usage and post-operative GERD (heartburn) between patients that had an endoscope used versus patients that had a suction calibration system used on them during "laparoscopic…
- Trial name
- NCT03939819
- Testing
- ViSiGi® 3D suction calibration device, Esophagogastroduodenoscopy (EGD) calibration
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Emory University
Neuromuscular Blockade
The Effect of Deep Block Versus Moderate Block on the Stress Response After Laparoscopic Gastrectomy
This study is a multicenter, randomized, controlled, double-blinded, and parallel design study. A total of 96 patients were decided to be recruited considering a 10% dropout rate.
- Trial name
- suga-SH (NCT02100280)
- Testing
- deep block
- Volunteers
- 96 people
- Sponsor
- Seoul National University Bundang Hospital
Gastric Resection
Gastric Tissue Stapler Comparison Study
This study is conducted to compare performance characteristics of staple lines resecting the stomach in excised human gastric tissue with existing Echelon Flex Powered Plus GST System (Ethicon, size: 60mm, "Echelon") stapler and…
- Trial name
- NCT04086433
- Testing
- gastric tissue resection
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Standard Bariatrics
Bariatric Surgery Candidate, Pain, Postoperative
The Effect of Liposomal Bupivacaine on Post Operative Pain and Narcotic Use After Bariatric Surgery
This study is prospective, randomized trial in which the efficacy of liposomal bupivacaine (Exparel®) is compared to standard bupivacaine local surgical site injection in reducing total IV and oral morphine equivalents required…
- Trial name
- Exparel (NCT03196505)
- Testing
- Exparel 266 MG Per 20 ML Injection, Bupivacaine
- Where
- United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco