Clinical trials: Gastric Submucosal Tumors
Esophageal Cancer, Esophageal Dysplasia
Comparison of O-type Hybrid Knife and IT Knife in ESD
By combining injection and dissection capability together, O-type Hybrid knife could possibly shorten the endoscopic submucosal dissection procedure for upper gastrointestinal neoplasms.
- Conditions
- Esophageal Cancer, Esophageal Dysplasia, Stomach Cancer, Stomach Dysplasia
- Trial name
- NCT01760070
- Testing
- Hybrid knife, IT knife
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastric Cancer
Evaluation of the Efficacy and Safety of Indocyanine Green Tracing in 3D Fluorescent Laparoscopic Lymph Node Dissection for Gastric Cancer
Purpose of the study To evaluate whether the clinical efficacy of submucosal injection of indocyanine green tracer laparoscopic gastric cancer lymph node dissection is superior to that of laparoscopic gastric cancer lymph node…
- Trial name
- NCT06421220
- Testing
- Preoperative injection of indocyanine green
- Where
- China
- Volunteers
- 484 people
- Sponsor
- Qilu Hospital of Shandong University
Tumor
Follow-up of the Natural Course of the Small EUS-suspected Gastric Gastointestinal Stromal Tumors
Gastric gastrointestinal stromal tumors (GISTs) less than 2 cm are usually followed up conservatively. However, little is known about the natural course of small GISTs.
- Trial name
- NCT01084460
- Sponsor
- National Taiwan University Hospital
Helicobacter Pylori, Early Gastric Cancer
Helicobacter Pylori Infection Status and Pathological Features for Predicting Gastric Cancer Biological Behavior and Prognosis: A Real-World Observational Study
This multicenter retrospective and prospective real-world observational study will evaluate the relationship of Helicobacter pylori (H.
- Trial name
- NCT07724496
- Testing
- 13C-Urea Breath Test, Serum Helicobacter pylori Antibody Testing, Pathological Assessment of Gastric Tissue
- Where
- 3 sites in China
- Volunteers
- 1,500 people
- Sponsor
- Chinese PLA General Hospital
Gastrointestinal Neoplasms, Abnormality of Enteric Nervous System Morphology
Endoscopic Vital Nerve Staining in Gastrointestinal Diseases
In this study, methylene blue (MB) was used as vital nerve staining agent. During gastroenteroscopy, mucosal nerve staining was achieved by endoscopic submucosal injection of MB solution.
- Trial name
- NCT05232357
- Testing
- Sodium thiosulfate and Methylene blue solution
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Early Gastric Cancer
A Clinical Trial to Evaluate the Sensitivity and Specificity of "WAYMED Endo" Compared to the Endoscopists in Classifying Early Gastric Cancer (EGC) Based on the Depth of Invasion in Endoscopic Images
The purpose of this clinical trial is to prove that the prediction capability of 'WAYMED endo' is superior to that of the endoscopists in classifying EGC based on the depth of invasion categories in gastro-endoscopic images.
- Trial name
- NCT06317103
- Testing
- WADYMED endo, Control group (the endoscopists)
- Where
- South Korea
- Volunteers
- 653 people
- Sponsor
- WAYCEN Inc
Early Gastric Cancer
Monitored Anesthesia Care With Propofol Plus Remifentanil During Endoscopic Submucosal Dissection: Evaluation of Bispectral Index Monitoring
There are clinical usefulness issues associated with bispectral index (BIS) for sedation of endoscopic submucosal dissection (ESD). However, the clinical usefulness of BIS for deep sedation is incompletely described.
- Trial name
- NCT01921283
- Testing
- BIS sensor attachment, no- BIS sensor attachment
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Yonsei University
Helicobacter Infections
Helicobacter Pylori and Proton Pump Inhibitor
The purpose of this study is to know the distribution of HP in stomach before use of PPI, during use of PPI, and after stop of PPI.
- Trial name
- NCT02449941
- Testing
- PPI (proton pump inhibitor)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Stomach Neoplasm
Finding ED90 of Flumazenil for Selective Improvement of Respiratory Distress by Remimazolam
Patients undergoing endoscopic submucosal dissection with monitored anesthesia care (MAC) using remimazolam may develop respiratory distress during the procedure.
- Trial name
- NCT06563063
- Testing
- Flumazenil
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Gastric Submucosal Tumors, Endoscopic Full Thickness Resection (EFTR)
EDLS-clips in Endoscopic Full-thickness Resection
A retrospective analysis was conducted on patients who visited from March 2022 to May 2024 and underwent endoscopic full-thickness resection and double-layer suture with titanium clips under endoscopy.
- Trial name
- NCT07305038
- Testing
- endoscopic double-layer suturing method with metallic clips
- Where
- China
- Volunteers
- 43 people
- Sponsor
- First Hospital of China Medical University
Interstitialoma, Endoscopic Surgery
A Study on the Safety and Effectiveness of Endoscopic Intracavitary Submucosal Dissection for Gastric Extracavitary-Type Submucosal Tumors
The aim of this study is to explore the safety and efficacy of endoscopic surgery in the treatment of extraluminal growing stromal tumors
- Trial name
- NCT07337980
- Testing
- Extraluminal growing stromal tumors treated endoscopically
- Volunteers
- 20 people
- Sponsor
- Zhongda Hospital
Early Gastric Cancer or Gastric Adenoma
Full-time RDI for ESD: Impact on Major Adverse Events and Procedure Time
Gastric cancer remains a major global health burden, ranking fifth in incidence worldwide and disproportionately affecting Asia, with China accounting for a significant share of cases and deaths.
- Trial name
- NCT07401303
- Testing
- ESD
- Where
- China
- Volunteers
- 640 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Indocyanine Green, Gastric Cancer
Randomized Controlled Trial on Effect of Lymph Node Mapping by Indocyanine Green Via Submucosal or Subserosal Injection
The purpose of this study was to evaluate whether submucosal or subserous injection of indocyanine green during laparoscopic lymphadenectomy for patients with gastric cancer was different.
- Conditions
- Indocyanine Green, Gastric Cancer, Injection Site
- Trial name
- NCT04219332
- Testing
- Subserosa injection of indocyanine green, submucosal injection of indocyanine green
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Fujian Medical University
Gastrointestinal Neoplasms, Gastric Cancer
Endoscopic Submucosal Dissection Registry
The purpose of this study is to monitor the success rates and completion rates for endoscopic submucosal dissection (ESD) for gastrointestinal (GI) cancers.
- Trial name
- ESD Registry (NCT01415609)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mayo Clinic
Early Gastric Cancer
Endoscopic Submucosal Dissection Versus Surgery in the Treatment of Early Gastric Cancer
In this study, patients who are going to undergo endoscopic submucosal dissection (ESD) or surgery for early gastric cancer will be enrolled and divided into ESD group and Surgery group according to the procedure they go through.
- Trial name
- NCT03857737
- Testing
- endoscopic submucosal dissection, Surgery
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Endoscopic Submucosal Dissection
Endoscopic Submucosal Dissection (ESD)- Master Slave Robotic System - Human Study
The purpose of this study is to evaluate the feasibility, ease and safety of flexible endoscopic robotic system to treat early gastric cancer in humans.
- Trial name
- ESD (NCT01394861)
- Testing
- ESD using Master Slave Robotic System
- Where
- India
- Volunteers
- 3 people
- Sponsor
- Asian Institute of Gastroenterology, India
Early Gastric Cancer
Comparison of the Sensitivity of pCLE and Pathological Biopsy for Gastric Mucosal Lesions
The pathological biopsy of gastric lesions, performed prior to endoscopic submucosal dissection (ESD), is crucial for differentiating the pathological nature of the lesions and guiding treatment decisions.
- Trial name
- pCLE (NCT07507071)
- Testing
- Probe-based Confocal Laser Endomicroscopy, Pathological biopsy
- Where
- China
- Volunteers
- 169 people
- Sponsor
- Changhai Hospital
Gastric Submucosal Tumors
Endofaster Robot for Gastroesophageal Submucosal Tumors: A Randomized Controlled Study
In endoscopic treatment for gastric submucosal tumors arising from the muscularis propria, does robot-assisted surgery yield a higher serosa preservation rate, shorter operative time and lower complication rates than conventional…
- Trial name
- NCT07655674
- Testing
- Robot system, Non-robotic conventional endoscopy
- Volunteers
- 110 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Early Gastric Cancer
Endoscopic Submucosal Dissection Versus Gastrectomy
Gastrectomy is curative treatment for early gastric cancer (EGC). Recently, endoscopic submucosal dissection (ESD) has been accepted as standard treatment in selected patients with negligible risk of lymph node metastasis.
- Trial name
- NCT02216110
- Testing
- Surgery
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Soonchunhyang University Hospital
Gastric Submucosal Tumors
A Randomized Controlled Clinical Study on the Application of the Third Space in the Operation of Gastric Submucosal Tumor
Gastric submucosal tumors (SMTs) are rare findings during routine upper endoscopy; the incidence of these lesions may be as high as 0.4%.SMTs display a wide spectrum,ranging from benign to highly malignant, with gastrointestinal…
- Trial name
- RECSINSMTs (NCT03612830)
- Testing
- Laparoscopy endoscopy cooperated surgery, Dan Vinchi robot endoscopy cooperated surgery
- Where
- China
- Volunteers
- 80 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University