Clinical trials: Gastric Symptoms
Gastroparesis
Enterra Therapy Clinical Study (Gastric Stimulation for Gastroparesis)
This study is to evaluate the safety and effectiveness of gastric stimulation in the reduction of nausea and vomiting in patients with gastroparesis using an approved Humanitarian device.
- Trial name
- NCT00157755
- Testing
- Enterra Therapy
- Where
- 6 sites in United States
- Volunteers
- 87 people
- Sponsor
- MedtronicNeuro
Gastrointestinal Neoplasia, Hirschsprung's Disease
Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy
To test the idea that submucosal endoscopy is effective and safe for endoscopic myotomy, endoscopic submucosal dissection, and access for tissue acquisition and resection.
- Conditions
- Gastrointestinal Neoplasia, Hirschsprung's Disease, Esophageal Obstruction, Gastroparesis
- Trial name
- NCT03626350
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Colorado, Denver
Gastric Cancer, Postoperative Delirium
Remimazolam for Reducing Postoperative Delirium in Elderly Patients Undergoing Laparoscopic Gastrectomy
This prospective, single-center, randomized, participant- and outcome assessor-blinded, parallel-group controlled trial evaluated whether remimazolam-based anesthesia reduced postoperative delirium (POD) and improved…
- Trial name
- NCT07351474
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 170 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Obesity, Morbid, Diabetes Mellitus, Type 2
Impact of an Increased Restrictive Factor of One Anastomosis Gastric Bypass on Metabolic Outcomes Type 2 Diabetes.
The purpose of the study is to evaluate the effect of an increased restrictive factor of one gastric anastomosis (OAGB) using a "FundoRing" fundoplication on metabolic outcomes in type 2 diabetes mellitus.
- Trial name
- NCT06176443
- Testing
- One anastomosis gastric bypass with combined fundoplication, One anastomosis gastric bypass without combined fundoplication
- Where
- Kazakhstan
- Volunteers
- 300 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Obesity, Type 2 Diabetes Mellitus
A Study to Examine Changes in GIP Plasma Levels Following Gastric Bypass Surgery in Obese Patients
Obesity is a multinational epidemic. There is evidence that despite educational measures and increased public awareness, the number of obese individuals continues to increase.
- Conditions
- Obesity, Type 2 Diabetes Mellitus, Insulin Resistance
- Trial name
- NCT00207389
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Boston Medical Center
Obesity
Assessment of Gastric Volume Reduction in Surgical Weight Loss Candidates
This trial will assess the feasibility of reduction gastroplasty with standard suture in bariatric patients who are candidates for surgical weight loss intervention.
- Trial name
- NCT00721227
- Testing
- Reduction Gastroplasty
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ethicon Endo-Surgery
Anal Cancer, Colorectal Cancer
Assessment of Symptom-Related Cytokines in Lung and Gastrointestinal (GI) Cancer Patients
Primary Objectives: To determine the feasibility of a study that would describe changes of certain circulating inflammatory cytokines (interleukin-1, 6, 8, 10, 12, and tumor necrosis factor-alpha [TNF] and symptoms related to…
- Conditions
- Anal Cancer, Colorectal Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00502502
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- M.D. Anderson Cancer Center
Squamous Cell Carcinoma of Head and Neck, Non-small Cell Lung Cancer
A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies
A Phase 1/2, open label, multi-center study to evaluate the safety, efficacy and tolerability of alomfilimab as single agent and in combination with anti-PD-L1 (atezolizumab) in adult patients with selected advanced malignancies…
- Conditions
- Squamous Cell Carcinoma of Head and Neck, Non-small Cell Lung Cancer, Hepatocellular Carcinoma, Esophageal Cancer
- Trial name
- NCT03829501
- Testing
- Alomfilimab, Atezolizumab
- Where
- 22 sites in United States, Hungary and 4 more
- Volunteers
- 222 people
- Sponsor
- Kymab Limited
Gastric Cancer (GC), Malnutitrion
Combined Oral and Parenteral Nutritional Therapy After Gastrectomy for Gastric Cancer
Patients undergoing gastrectomy for gastric cancer frequently experience insufficient oral intake during the postoperative recovery period because of reduced gastric capacity, early satiety, and gastrointestinal symptoms.
- Trial name
- BRIDGE-GC (NCT07604857)
- Testing
- Oral Nutritional Supplementation, Parenteral Nutrition, Standard Postoperative Nutritional Care
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Kyo Young Song
Obesity
A Prospective Study Evaluating The Utility of Transnasal Endoscopy With Roux en Y Gastric Bypass
Improvements in imaging technology have allowed for the development of small endoscopes ("slim scopes") half the size of a typical endoscope.
- Trial name
- NCT01526772
- Testing
- Endoscopy
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Cancer
Ondansetron With/Out Dexamethasone to Prevent Vomiting in Patients Receiving Radiation to the Upper Abdomen
RATIONALE: Antiemetic drugs may help to reduce or prevent vomiting in patients treated with radiation therapy. It is not yet known if ondansetron is more effective with or without dexamethasone in preventing vomiting caused by…
- Trial name
- NCT00016380
- Testing
- dexamethasone, ondansetron, quality-of-life assessment
- Where
- 14 sites in Canada
- Volunteers
- 211 people
- Sponsor
- NCIC Clinical Trials Group
Postoperative Pain
Postoperative Analgesic Effect of Subcostal TAPB for Laparoscopic Gastrectomy
This prospective, randomized, single blinded study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided subcostal transversus abdominis plane block in gastric cancer patients undergoing…
- Trial name
- NCT04138901
- Testing
- Ultrasound guided subcostal transversus abdominis plane block (TAPB), Ropivacaine 0.75% Injectable Solution, 21G 100 mm stimulator needle (Echoplex®, Vygon, Ecouen, France)
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Seoul National University Hospital
Adenocarcinoma Gastric Stage IV With Metastases, Adenocarcinoma - GEJ
DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02)
This study will find out if trastuzumab deruxtecan is safe and works for participants with gastric or gastroesophageal junction cancer.
- Trial name
- NCT04014075
- Testing
- Trastuzumab deruxtecan
- Where
- 37 sites in United States, Belgium and 3 more
- Volunteers
- 79 people
- Sponsor
- Daiichi Sankyo
Acute Kidney Injury, Cirrhosis
Impact of Nonselective Beta-blocker on Acute Kidney Injury in Cirrhotic Patients With Esophageal Varices
We will include patients with EV and EVB. They will be randomized to EVL vs. NSBB for primary prevention And EVL+long-term NSBB vs. EVL+short-term NSBB for secondary prevention. 150 patients will be included in a 3-year period.
- Conditions
- Acute Kidney Injury, Cirrhosis, Esophageal Varices
- Trial name
- AKI (NCT04074473)
- Testing
- propranolol, Esophageal varice ligation, DC propranolol
- Where
- Taiwan
- Volunteers
- 170 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Constipation
Functional Magnetic Stimulation Enhances Gastrointestinal Motility in Patients With Chronic Constipation
The purpose of this study is to evaluate the effects of Functional Magnetic stimulation (FMS) on gastrointestinal motility in patients suffering from chronic constipation due to non-neurological issues.
- Trial name
- NCT01786837
- Testing
- Functional Magnetic Stimulation
- Where
- United States
- Sponsor
- The Cleveland Clinic
Bariatric Surgery, Morbid Obesity
Use of an Endoluminal-suturing Device for Endoscopic Gastric Reduction as an Aid for Class I Obesity, or Class II Obesity Without Comorbidity
The primary objective is to measure the impact of this treatment for patients with obesity of class I, or class II without co-morbidity, assessed by excess weight loss (EWL)>25%.
- Trial name
- SLEEVE (NCT03900481)
- Testing
- Vertical gastric plication
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Obesity
Evaluation of Omentopexy on Gastro-oesophageal Reflux Following Sleeve Gastrectomy
The aim of the study is to assess impact of omentopexy on de novo gastro-oesophageal reflux disease (GERD) after sleeve gastrectomy. This will be assess 2 years postoperatively.
- Trial name
- Sleevepexie (NCT04994665)
- Testing
- sleeve gastrectomy, sleeve gastrectomy with omentopexy
- Where
- 9 sites in France
- Volunteers
- 526 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Pulmonary Aspiration During Anaesthetic Induction
Effects of Beginning a GLP1-Agonist Therapy on Residual Gastric Content and Gastric Emptying
This project explores the elevated risk of pulmonary aspiration during anesthesia in patients undergoing GLP-1 agonist therapy, which prolongs gastric emptying.
- Trial name
- GLP-1 (NCT06659159)
- Testing
- Gastric ultrasound
- Volunteers
- 50 people
- Sponsor
- Sascha Battig
Gastrointestinal Dysfunction, Hemorrhage
Daytime Variation of Complication in Gastric and Pancreatic Surgery
Evaluate the daytime variation of complications in gastric and pancreatic surgery
- Conditions
- Gastrointestinal Dysfunction, Hemorrhage, Infection, Fistula
- Trial name
- NCT03383562
- Testing
- operation in different stages of the day
- Volunteers
- 200 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Helicobacter Gastritis, Dyspepsia
Activation and Recruitment of GIL During Hp Infection
Helicobacter pylori is a major human pathogen that infects over half of the world population. Infection initiates a series of changes in the gastric mucosa, beginning with gastritis and leading in some patients to peptic ulcer…
- Trial name
- NCT00275886
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.