Clinical trials: Gastric Symptoms
Obscure Gastrointestinal Bleeding, Angiodysplasia
Long-term Effects of Thalidomide for Recurrent Gastrointestinal Bleeding Due to Vascular Malformation
Background: Repeated episodes of bleeding from gastrointestinal vascular malformations refractory to endoscopic or surgical therapy often pose a major therapeutic challenge.
- Conditions
- Obscure Gastrointestinal Bleeding, Angiodysplasia, Gastric Antral Vascular Ectasia, Thalidomide
- Trial name
- NCT00964496
- Testing
- Thalidomide, Iron
- Volunteers
- 55 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Chronic Atrophic Gastritis, Depressive Symptoms
Objective Vascular Biomarkers as Triage for Depression in Chronic Atrophic Gastritis
Depressive symptoms are highly prevalent in patients with chronic atrophic gastritis (CAG) but are frequently under-detected due to stigma and reliance on subjective questionnaires.
- Conditions
- Chronic Atrophic Gastritis, Depressive Symptoms, Depression, Gastrointestinal Diseases
- Trial name
- NCT07319338
- Testing
- Vascular-Psychological Triage Workflow
- Where
- 4 sites in China
- Volunteers
- 520 people
- Sponsor
- China Academy of Chinese Medical Sciences
Gastro Esophageal Reflux
Efficacy and Safety of EsoDuo®
Clinical Trial to Evaluate the Effects of EsoDuo® in Controlling Reflux Symptoms Related to the Acid
- Trial name
- NCT06430047
- Testing
- EsoDuo® Tablet
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Peptic Ulcer Hemorrhage, Peptic Ulcer, Acute With Hemorrhage
Efficacy of Low Dose Intravenous Proton Pump Inhibitor for Peptic Ulcer Bleeding
We prepare this study to compare the efficacy of intermittent intravenous PPI infusion (relatively low dose PPI therapy) than continous PPI infusion method.
- Conditions
- Peptic Ulcer Hemorrhage, Peptic Ulcer, Acute With Hemorrhage, Peptic Ulcer, Proton Pump Inhibitor Overdose
- Trial name
- NCT03814421
- Testing
- intermittent (40mg as a bolus injection daily for 72hours)
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Changwon Hospital
Obesity / Overweight
Effects of Tirzepatide on Gut Microbiota and Gastrointestinal Function After Drug Withdrawal in Obese Patients
This is an observational cohort study. The primary objective is to analyze the dynamic changes in gut microbiota and metabolic profiles in obese patients treated with Tirzepatide.
- Trial name
- NCT07847515
- Testing
- Tirzepatide
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Obesity (BMI>30), Obesity (BMI > 35)
FABP4 Response After Roux-en-Y Gastric Bypass
This retrospective observational cohort study examined serum fatty acid-binding protein 4 (FABP4) dynamics in 28 adults who underwent Roux-en-Y gastric bypass (RYGB), followed at baseline, 3 months, and 6 months.
- Conditions
- Obesity (BMI>30), Obesity (BMI > 35), Insulin Resistance, Bariatric Surgery
- Trial name
- FABP4-RYGB (NCT07774208)
- Volunteers
- 28 people
- Sponsor
- Istanbul University
Gastrointestinal Cancer
Validating M.D. Anderson Symptom Inventory (MDASI-GI) in GI Cancer Patients Under Chemotherapy
The goal of this study is to learn more about the symptoms that may occur in patients with GI cancer. The types of GI cancer being studied are cancers of the stomach, liver, pancreas, colon, and rectum.
- Trial name
- NCT00849979
- Testing
- Questionnaire, Interview
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- M.D. Anderson Cancer Center
Gastric Cancer, Postoperative Delirium
Remimazolam for Reducing Postoperative Delirium in Elderly Patients Undergoing Laparoscopic Gastrectomy
This prospective, single-center, randomized, participant- and outcome assessor-blinded, parallel-group controlled trial evaluated whether remimazolam-based anesthesia reduced postoperative delirium (POD) and improved…
- Trial name
- NCT07351474
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 147 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Idiopathic Gastroparesis, Diabetic Gastroparesis
Intraluminal Endosonography for Examination of the Structural Changes of the Stomach in Gastroparetic Patients
Patients who empty their stomach slowly may have what we call "Slow gastric emptying" or "gastroparesis". These patients can have some changes in the thickness of their stomach wall.
- Trial name
- NCT01916460
- Testing
- Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Obesity, Diabetes
Crossover Trials Which Assessed Consumption of Slowly Digestible Carbohydrates for 21 Days on Gastric Emptying Rates
To gain a better understanding about the conditioning effect of consumption of slowly digestible carbohydrate on gastric emptying rate, respiratory quotient and metabolic flexibility, this study will focus on monitoring change in…
- Trial name
- INT (NCT05430061)
- Testing
- slowly digestible carbohydrate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Purdue University
Obesity
Identification of In-vivo Probe Based Confocal Laser Endomicroscopy Cellular Characteristics in Obese Women
Previous studies have shown that histological changes in the gastric mucosa between obese and non-obese individuals do exist. Understanding these histological differences (between obese and non-obese individuals) might elucidate…
- Trial name
- NCT02781961
- Testing
- cellvizio
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Sheba Medical Center
Intraabdominal Abscess After Procedure, Leakage
Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation
Despite advances in laparoscopic surgery for perforated peptic ulcer (PPU), intra-abdominal abscess (IAA) is recognized as one of the commonly reported complications with relation to the extent of infectious abdominal…
- Conditions
- Intraabdominal Abscess After Procedure, Leakage, Pneumonia, Operation Wound; Infection
- Trial name
- NCT05147870
- Testing
- Peritoneal irrigation, Suction only
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Chang Wei-Jung
Cancer of Esophagus, Gastric Cancer
Analysis of Body Composition in Relation to Outcome After Surgery in a Cohort of Patients With Esophageal Cancer
The occurrence of dysphagia is a well-known early feature of esophageal cancer that may reduce caloric intake and thus cause weight loss. Sarcopenia is considered to be a consequence of such involuntary nutritional restriction.
- Trial name
- NCT03032224
- Testing
- Resection of the esophagus and the gastroesophageal junction
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Vastra Gotaland Region
Morbid Obesity
Stool Analysis After Sleeve Gastrectomy vs Gastric Bypass
The goal of this observational study is to learn whether routine stool tests can detect changes in gut function 6 months after two common types of weight loss surgery: sleeve gastrectomy and gastric bypass (including mini gastric…
- Trial name
- NCT07461610
- Testing
- Laparoscopic Sleeve Gastrectomy, Mini Gastric Bypass, Roux-en-Y Gastric Bypass
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Obesity
Bariatric Surgery: Microbiome & Diabetes
This study is a prospective cohort study, following 80 morbidly obese patients undergoing bariatric surgery, specifically Roux-en-Y gastric bypass (RYGB).
- Trial name
- NCT03723486
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University Health Network, Toronto
Patients With Gastroparesis Who Have Failed Standard Therapy
Domperidone for the Treatment of Chronic Nausea and Vomiting Secondary to Gastroparesis
To provide oral domperidone to patients between the ages of 18 and 60 years of age, according to the investigator's judgment, a prokinetic effect is needed for the relief of severe gastroparesis.
- Trial name
- NCT01711918
- Testing
- Domperidone
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Ron Schey
GERD
Effect of Coffee on Gastro-Esophageal Disease in Patients With Symptoms of Reflux
Investigation evaluating the effect of coffee on gastro-esophageal reflux disease.
- Trial name
- NCT00584259
- Testing
- Coffee
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of California, Davis
Postoperative Dumping Syndrome
Study to Assess Safety and Efficacy of sc Pasireotide in Patients With Dumping Syndrome
Dumping Syndrome consists of (1) a too rapid gastric emptying, (2) an inappropriate release of GI hormones (as a reaction to the hyperosmolar contents in the duodenum) and (3) an hyperinsulinemic response to a too rapid…
- Trial name
- CSOM230BBE01T (NCT01895296)
- Testing
- Pasireotide
- Where
- Belgium
- Volunteers
- 9 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
GERD (Gastroesophageal Reflux Disease), NERD
New Topical tReatment Options for Symptomatic patiEnts With Nonerosive gastroesophageaL Reflux dIsease (The RELIEF Trial)
The goal of this randomized, double-blind, single-center clinical trial RELEIF is to learn if medical devices work to decrease symptoms of gastroesophageal reflux disease (GERD) in adults' patients.
- Conditions
- GERD (Gastroesophageal Reflux Disease), NERD, Heartburn, Regurgitation, Gastric
- Trial name
- RELIEF (NCT07624383)
- Testing
- Esophageal barrier medical device
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Cellmedis
Stomach Neoplasm, Lymph Node Metastasis
Molecular Imaging of Gastric Cancer Metastatic Lymph Nodes with 99mTc-3PRGD2 Probe.
Surgical lymph node dissection is the key to advanced gastric cancer. In recent years, after the overall implementation of standard D2 dissection, lymph node dissection for gastric cancer began to explore the direction of D1+…
- Conditions
- Stomach Neoplasm, Lymph Node Metastasis, RADIONUCLIDE IMAGING
- Trial name
- NCT06435741
- Testing
- 99mTc-3PRGD2 Spect-CT scan
- Volunteers
- 30 people
- Sponsor
- Peking University Cancer Hospital & Institute
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