Clinical trials: Gastric Symptoms
Gastroesophageal Reflux Disease
Symptom Assessment for Patients With Gastro-esophageal Reflux Disease Receiving Helicobacter Pylori Eradication
Background: Rebound acid hypersecretion and acid-related symptoms after discontinuation of proton-pump inhibitor has been reported in previous studies.
- Trial name
- NCT02934152
- Testing
- H pylori eradication, H pylori eradication timing
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Gastric Cancer, Nutrition Related Cancer
Effect of Exercise and Enteral Nutrition on Survival
The present clinical trial was designed to explore the effect of postoperative physical exercise combined with enteral nutritional supplement on 3-year disease-free survival in patients with advanced gastric cancer.
- Conditions
- Gastric Cancer, Nutrition Related Cancer, Sarcopenia
- Trial name
- ENERGY (NCT05959226)
- Testing
- Exercise Intervention, Nutrition Intervention
- Volunteers
- 960 people
- Sponsor
- The First Hospital of Jilin University
Gastroparesis
The Use Of Domperidone For The Relief Of Refractory Upper Gastrointestinal GI Symptoms
To prescribe oral domperidone for patients with upper GI symptoms who have failed or suffered adverse effects from standard medical therapy.
- Trial name
- NCT03810287
- Testing
- Domperidone
- Where
- United States
- Sponsor
- Yale University
Morbid Obesity
Laparoscopic Gastric Bypass Versus Sleeve Gastrectomy to Treat Morbid Obesity
Bariatric surgery in the treatment of morbid obesity is associated with long-term weight-loss and decreased overall mortality. Long-term results have been reported for laparoscopic gastric bypass procedures but the long-term…
- Trial name
- SLEEVEPASS (NCT00793143)
- Where
- 4 sites in Finland
- Volunteers
- 240 people
- Sponsor
- Turku University Hospital
Obesity
How Does Bariatric Surgery Affect Social Experiences and Well-being - The BaSES-study
Nonrandomized controlled trial to assess whether or not sleeve gastrectomy (SG) or Roux-en-Y gastric bypass (RYGB) affect social experiences and biomarkers of well-being 6 weeks and 1 year after surgery.
- Trial name
- BaSES (NCT05207917)
- Testing
- Gastric bypass, Sleeve gastrectomy, Single anastomosis sleeve ileal (SASI) bypass
- Where
- Norway
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- The Hospital of Vestfold
Laparoscopic Gastric Bypass, Obesity
Ketamine vs Hydromorphone
This study will help to determine if investigators can minimize narcotic use in laparoscopic gastric bypass patients while maintaining adequate pain control.
- Conditions
- Laparoscopic Gastric Bypass, Obesity, Pain, Postoperative
- Trial name
- NCT03001843
- Testing
- Ketamine, Narcotics, pain scale
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Florida
the Management of Weight Regain After Gastric Bypass by Endoscopic Suturing
Assessment of the Overstich Technique for the Management of Weight Regain After Gastric Bypass.
Prospective multicenters randomized study to compare the efficiency and the socioeconomic impact of the endoscopic management (Overstitch technique) of weight regain after gastric bypass surgery to non invasive treatment
- Trial name
- APOLLO (NCT02048033)
- Testing
- Regular endoscopy + endogastric suturing, Regular endoscopy
- Where
- 7 sites in France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Gastric Adenocarcinoma, Esophagus Adenocarcinoma
Oxaliplatin ± Nivolumab in Combination With Trifluridine/Tipiracil or 5-fluorouracile in Frail Patients With Advanced, Recurrent or Metastatic Gastric, Oesophageal or Gastroesophageal Junction Cancer
Oxaliplatin ± nivolumab in combination with trifluridine/tipiracil or 5-fluorouracile (5-FU) in frail patients with advanced, recurrent or metastatic gastric, oesophageal or gastroesophageal junction cancer.
- Conditions
- Gastric Adenocarcinoma, Esophagus Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
- Trial name
- LOGICAN (NCT05476796)
- Testing
- Trifluridine/Tipiracil, Oxaliplatin, FOLFOX regimen
- Where
- 28 sites in France
- Volunteers
- 118 people
- Sponsor
- UNICANCER
Localized Oesogastric Adenocarcimona, MSI and or dMMR
Pre-operative Nivolumab and Ipilimumab, Followed by Post-operative Nivolumab, for MSI/dMMR Oeso-gastric Adenocarcinoma.
This is a non-randomized study, open label phase II study. The purpose of this study is to evaluate the complete pathologic response rate (cPRR) with neoadjuvant nivolumab and ipilimumab combination in patients with MSI and/or…
- Trial name
- NEONIPIGA (NCT04006262)
- Testing
- Nivolumab 10 MG/ML, Ipilimumab 200 MG in 40 ML Injection
- Where
- 15 sites in France
- Volunteers
- 32 people
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Gastric Emptying, Gastroparesis
Gastric Emptying Recovery After GLP-1 RA Cessation
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) can delay gastric emptying and may increase residual gastric contents before general anesthesia.
- Conditions
- Gastric Emptying, Gastroparesis, Preoperative Care
- Trial name
- NCT07360262
- Testing
- Preoperative gastric ultrasound
- Where
- 2 sites in South Korea
- Volunteers
- 186 people
- Sponsor
- Wonkwang University Hospital
Nausea
Reducing Up-set Stomach and Vomiting After Surgery Using Essential Oils
The purpose of this study is to determine if aromatherapy (essential oil) is effective at reducing up-set stomach and vomiting after surgery and in reducing the need for up-set stomach medications
- Trial name
- NCT03370328
- Testing
- Peppermint oil, Ginger oil
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Rochester
Obesity
Does Weight Loss Surgery and Probiotic Supplementation Lead to a "Lean" Gut Microbiota?
The purpose of the weight-loss study is to characterize the effect of LGG supplementation on the relative abundance of phyla in the gut microbiota of patients undergoing gastric bypass and sleeve gastrectomy surgery, and to…
- Trial name
- NCT01870544
- Testing
- Lactobacillus Rhamnosus GG
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Tufts Medical Center
Upper Gastrointestinal Bleeding
Gastric CLEANsing by Intravenous AZithromycin in Urgent Endoscopy
This study will test the hypothesis that azythromycin is efficient and safe in cleansing the upper gastrointestinal tract for endoscopic examination in the case of acute bleeding.
- Trial name
- CLEAN-AZ (NCT06077916)
- Testing
- Azithromycin, Saline solution
- Where
- Romania
- Volunteers
- 224 people
- Sponsor
- Clinical Hospital Colentina
Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD)
Indiana University Gastrointestinal Motility Diagnosis Registry
Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions.
- Conditions
- Eosinophilic Esophagitis, Gastroesophageal Reflux Disease (GERD), Gastroparesis, Functional Vomiting
- Trial name
- NCT04506593
- Testing
- no intervention
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Indiana University
Gastritis, Peptic Ulcer
Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Bismuth-containing Quadruple Therapy
This study aims at evaluating efficacy and safety of berberine-containing quadruple therapy(berberine, esomeprazole, clarithromycin and amoxicillin) versus bismuth-containing quadruple therapy (bismuth,esomeprazole,clarithromycin…
- Conditions
- Gastritis, Peptic Ulcer, Dyspepsia
- Trial name
- NCT02296021
- Testing
- Berberine, Bismuth, esomeprazole
- Where
- China
- Volunteers
- 612 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Gastric Cancer, Frailty
Analysis of Influencing Factors of Preoperative Frailty in Elderly Patients With Gastric Cancer Based on the Health Ecology Theory
Frailty is common in patients with gastric cancer undergoing surgical treatment. Preoperative frailty can lead to many adverse outcomes in patients after surgery.
- Trial name
- NCT04929587
- Testing
- This is a observational research, there is no intervention
- Where
- China
- Volunteers
- 406 people
- Sponsor
- Nanjing Medical University
Obesity
Transradial Selective Catheterization of the Celiac Artery in Obese Patients
BACKGROUND: Obesity, with its associated comorbidities, is set to become a major risk factor for cardiovascular disease in the 21st century.
- Trial name
- NCT03434665
- Testing
- Transradial celiac artery angiography
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- Laval University
Advanced Solid Tumors, Gastric Cancer
PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumors
The purpose of this study is to assess the safety and effects of PF-07265028 as monotherapy and in combination with sasanlimab. The study aims to identify the maximum tolerated dose (MTD) of PF-07265028 as monotherapy; evaluate…
- Conditions
- Advanced Solid Tumors, Gastric Cancer, Gastroesophageal Junction Cancer, Urothelial Cancer
- Trial name
- NCT05233436
- Testing
- PF-07265028, Sasanlimab
- Where
- 8 sites in United States, Japan
- Volunteers
- 21 people
- Sponsor
- Pfizer
Type 2 Diabetes, Morbid Obesity
The Effect of a Gastric Bypass on Type 2 Diabetes in the Morbidly Obese Patient
Proof of concept, of RYGBP and its capabilities to cure type 2 diabetes (DM 2) and sleep apnea has already been recognized in the reports on weight loss surgery.
- Trial name
- NCT01086111
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Gasthuisberg
Gastric Cancer (GC), Postoperative Recovery
Early Postoperative Intervention in Gastric Cancer Patients
This study was conducted by Qilu Hospital and five other renowned medical centers, aiming to evaluate the impact of early structured postoperative intervention on quality of life and prognosis in patients with gastric cancer…
- Trial name
- NCT07444099
- Testing
- Early structured postoperative intervention encompassing nutrition, psychology, and exercise
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Qilu Hospital of Shandong University
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