Clinical trials: Gastric Symptoms
Obesity, Morbid, Anastomosis
Regain Rate According to gj Anastomosis Size in Gastric Bypass
Obesity has become an important medical and social problem in western countries today. Roux-en-Y gastric bypass (LRYGB) is the most commonly performed surgery for the treatment of morbid obesity in the United States.
- Conditions
- Obesity, Morbid, Anastomosis, Roux-en-y Anastomosis Site
- Trial name
- NCT05655975
- Testing
- upper gi endoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Recurrent Gastric Cancer
A Study of Genomic-guided 'Standard-of-care' Chemotherapy for in Advanced Gastric Cancer Patients
This is an open, non-randomized, multicenter Phase II study evaluating cisplatin plus TS-1 or oxaliplatin plus TS-1 as first-line therapy in predicted 'responder' to platinum and fluoropyrimidine.
- Trial name
- 3G (NCT01100801)
- Testing
- TS-1 with cisplatin, TS-1 with oxaliplatin
- Where
- Singapore
- Volunteers
- 90 people
- Sponsor
- National University Hospital, Singapore
Clinically Severe Obesity, Obesity Recidivism
Adding Malabsorption for Failed Gastric Bypass
The main aim of this study is to analyze and report the preliminary and intermediate term outcomes after laparoscopic revision Roux-en-Y gastric bypass surgery for weight recidivism.
- Conditions
- Clinically Severe Obesity, Obesity Recidivism, Inadequate Initial Weight Loss, Poor Weight Loss
- Trial name
- NCT01040481
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, San Francisco
Esophagectomy, Dumping Syndrome
Dumping Syndrome After Esophagectomy
Background: Dumping syndrome is a common complication for patients who have undergone surgery for esophageal cancer. It occurs when food moves too quickly from the stomach (or the reconstructed gastric tube) into the small…
- Conditions
- Esophagectomy, Dumping Syndrome, Continous Glucose Measurement
- Trial name
- NCT07605481
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Obesity, Morbid
Effect of Milk-free Diet on Weight and Irritable Bowel Syndrome in Morbid Obesity
Innlandet Hospital in Gjøvik is a center for patients suffering from morbid obesity in Hedmark og Oppland, Norway. Patients with either BMI > 40 kg/m2 or with BMI > 35 kg/m2 and complications who opt for "gastric bypass" surgery…
- Trial name
- NCT01686919
- Testing
- milk-free
- Sponsor
- Norwegian University of Science and Technology
Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis
Biomagnetic Characterization of Gastric Dysrhythmias III
There is a tremendous clinical need for a noninvasive technique that can assess gastric electrical activity and would be repeatable without any exposure to radiation.
- Conditions
- Diabetics Without Symptoms of Gastroparesis, Diabetic Gastroparesis, Idiopathic Gastroparesis, Total or Partial Gastrectomy
- Trial name
- NCT03176927
- Testing
- magnetogastrogram
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Astrocytoma, Brain Cancer
Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S
This is a multi-center, open-label, dose escalation study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and maximum tolerated dose (MTD) of QBS10072S in patients with advanced or metastatic cancers…
- Conditions
- Astrocytoma, Brain Cancer, Brain Metastases, Bladder Cancer
- Trial name
- NCT04430842
- Testing
- QBS10072S
- Where
- 2 sites in Australia
- Volunteers
- 15 people
- Sponsor
- Quadriga Biosciences, Inc.
Postoperative Pain
Impact of Implementation of an Enhanced Recovery After Surgery Program in Laparoscopic Roux-en-Y Gastric Bypass
A prospective randomized study of patients undergoing Roux-en-Y gastric bypass will be randomized in 2 groups: those following an ERAS program and those ones following a standard protocol.
- Trial name
- NCT03212573
- Testing
- ERAS protocol, Standard care
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital General Universitario Elche
Organ Failure, Multiple, Indigestion
The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients
Critically ill patients are at risk of or suffering from one or more key organs or organ system failure. This study will measure the effect of traditional Chinese medicine(TCM) interventions on critically ill patients admitted to…
- Conditions
- Organ Failure, Multiple, Indigestion, Delayed Gastric Emptying, Respiratory Failure
- Trial name
- NCT06452966
- Testing
- traditional Chinese medicine, Routine ICU care, historical Routine ICU care
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- China Medical University Hospital
Esophageal Varices, Bleeding
Self-expandable Esophageal Stent Versus Balloon Tamponade in Refractory Esophageal Variceal Bleeding.
In the last years, important advances have been done in the treatment and prevention of esophageal variceal bleeding. Experts agree that the combination of pharmacological and endoscopic therapy should be the first line therapy…
- Conditions
- Esophageal Varices, Bleeding, Cirrhosis
- Trial name
- NCT01242280
- Testing
- Stent, Tamponade
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Hospital Clinic of Barcelona
Respiration Disorders, Respiratory Disease
The Gut-Lung Axis and Respiratory Illness in Children
The goal of this single-centre observational study conducted at the Royal Hospital for Children in Glasgow, Scotland, is to employ a multi-omics approach to investigate the "gut-lung axis" in health and disease.
- Conditions
- Respiration Disorders, Respiratory Disease, Asthma in Children, Wheezing
- Trial name
- NCT06271213
- Testing
- observational only - no interventions as part of study
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Morbid Obesity
The Influence of Aerobic Endurance Training After Roux-en-Y-Gastric Bypass
The aim of this study was to assess the efficiency of aerobic physical exercise (APE) on weight loss, body composition and co-morbidities in patients after laparoscopic Roux-en-Y Gastric bypass (RYGBP).
- Trial name
- AET (NCT00875186)
- Testing
- aerobic endurance training
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
Obesity, Surgery
Gastric Bypass, Gastric Band or Sleeve Gastrectomy to Treat Obesity
Obesity is an increasing health problem in the United Kingdom (UK) and is predicted to worsen. In the UK and worldwide the three most commonly performed operations are laparoscopic adjustable gastric banding ('BAND surgery')…
- Conditions
- Obesity, Surgery, Quality of Life, Weight Loss
- Trial name
- ByBandSleeve (NCT02841527)
- Testing
- Gastric Band, Gastric Bypass, Sleeve Gastrectomy
- Where
- 12 sites in United Kingdom
- Volunteers
- 1,351 people
- Sponsor
- University of Bristol
Parkinson's Disease, Gastroparesis
RQ-00000010 for Gastroparesis and Constipation in Parkinson's Disease
This is a study to determine the safety and tolerability of a new medicine (RQ10) for gastrointestinal symptoms in Parkinson's disease.
- Conditions
- Parkinson's Disease, Gastroparesis, Constipation
- Trial name
- RQ-10 (NCT02838797)
- Testing
- RQ-00000010
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Virginia Commonwealth University
Advanced Malignancies, Metastatic Cancer
Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic Malignancies
The purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01876 when given in combination with immune therapies in subjects with advanced or metastatic malignancies.
- Trial name
- NCT03126110
- Testing
- INCAGN01876, Nivolumab, Ipilimumab
- Where
- 38 sites in United States, Australia and 2 more
- Volunteers
- 145 people
- Sponsor
- Incyte Biosciences International Sàrl
Obesity, Morbid
Omega Gastric Bypass (150cm) Compared to the Roux-en-Y Gastric Bypass (YOMEGA-2 Multicentric Trial)
Obesity with its consequences such as type 2 diabetes, high blood pressure, dyslipidemia, fatty liver disease, sleep apnea and cancers, remains a major healthcare problem worldwide.
- Trial name
- YOMEGA-2 (NCT06057597)
- Testing
- Laparoscopic OAGB, Laparoscopic RYGB
- Where
- France
- Volunteers
- 368 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Revisional Bariatric Surgery
Comparing Revisional Laparoscopic Roux-en-Y Gastric Bypass Versus Ringed Revisional Roux-en-Y Gastric Bypass After Laparoscopic Sleeve Gastrectomy
Obesity remains a major global health challenge, with rising prevalence and significant metabolic, cardiovascular, and gastrointestinal comorbidities.
- Trial name
- NCT07436013
- Testing
- Standard revisional RYGB, Revisional Banded RYGB
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Obesity, Bariatrics
Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy
Propofol is one of the most popular anesthetic drugs used for sedation during upper gastrointestinal endoscopies due to its quick onset and quick resolution of symptoms allowing patients to leave the hospital sooner.
- Conditions
- Obesity, Bariatrics, Sleep Apnea Syndromes, Gastric Bypass
- Trial name
- NCT02643979
- Testing
- Ketofol, Propofol, Saline
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obesity, Gastric Bypass
Impact of a Specific Micronutrient-probiotic-supplement on Fatty Liver of Patients After Mini-Gastric Bypass Surgery
Aim of this prospective randomized intervention study is to evaluate the effect of a dietary intervention with a specific micronutrient-probiotic-combination for 12 weeks on fatty liver and cardiometabolic status in obese…
- Conditions
- Obesity, Gastric Bypass, NAFLD
- Trial name
- FMG-01 (NCT03585413)
- Testing
- Micronutrient-probiotic-combination
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Bonn Education Association for Dietetics r.A., Cologne, Germany
Obesity
Effect of Oral Feeding on Gastric Emptying, Gut Blood Flow, and Hormone Responses in Obese and Healthy Weight Subjects
Obesity is a complicated condition that is poorly understood. The aim of this study is to increase our knowledge of how the condition may arise, and what makes obese people remain obese.
- Trial name
- NCT03860623
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
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