Clinical trials: Gastric Symptoms
Pulmonary Aspiration of Gastric Contents
SMART Study (Sellick's Maneuver Assisted Real Time) to Deliver Target Cricoid Pressure in Simulated Environment
Cricoid force is applied during airway management to prevent pulmonary aspiration of regurgitated gastric contents. This force is usually applied by a nurse or anaesthesia assistant.
- Trial name
- NCT02749175
- Testing
- Cricoid force sensor monitor system
- Where
- Singapore
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Obesity, Morbid, Suture, Complication
Stapler-less Burst Pressure in a Ex-vivo Human Gastric Tissue
Stapler-less laparoscopic sleeve gastrectomy (LSG) is emerging as a new potential affordable cost-effective alternative procedure. However, no pre-clinical data are currently available on human tissue.
- Conditions
- Obesity, Morbid, Suture, Complication, Suture Rupture
- Trial name
- NCT04488042
- Testing
- Stapler-less gastrectomy, Suture
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Campania Luigi Vanvitelli
Dyspepsia, Gastroparesis
Virtual Poetry Workshops to Enhance Patient Well Being and Reduce Anxiety
This study examines whether participating in poetry workshops can improve emotional well-being among patients with chronic digestive symptoms.
- Conditions
- Dyspepsia, Gastroparesis, Anxiety, Depression
- Trial name
- NCT07717541
- Testing
- Poetry, Poetry Manual
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Ohio State University
Gastrointestinal Fistula, Gastrointestinal Perforation
Endoscopic Treatment of Intestinal Fistulas and Perforations
Gastrointestinal leaks or perforations are currently treated through either open or laparoscopic surgical procedures. The purpose of this research is to determine whether new endoscopic tools are safe and effective in the…
- Trial name
- NCT01303653
- Testing
- endoscopic closure of gastrointestinal fistulas and perforations
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Oregon Clinic
Upper GI Bleeding, Bleeds Gastric
Metoclopramide in Upper Gastrointestinal Bleed
The goal of this clinical trial is to test if metoclopramide can improve effectiveness of endoscopic intervention in upper gastrointestinal (GI) bleeds.
- Conditions
- Upper GI Bleeding, Bleeds Gastric, Bleed Ulcer, Hemorrhage Gastric
- Trial name
- NCT05746377
- Testing
- Metoclopramide 10mg, Saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mercy Health System
Hematological Disease, Delayed Gastric Emptying
Randomized Trial:the Effect of Liquid Food on the Intake of Energy and Protein in Malignant Hematologic Patients
The study investigates the effect of liquid food on the intake of energy and protein compared to solid food. One group will receive dietary counselling in fulfilling their need for energy and protein from liquid food and the…
- Conditions
- Hematological Disease, Delayed Gastric Emptying, Malignant Disease
- Trial name
- NCT02447237
- Testing
- dietary counselling
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Jens Rikardt Andersen
Morbid Obesity
Banded Versus Non-banded Roux-en-Y Gastric Bypass
This is a prospective randomized Study comparing Weight loss, Esophageal Motility and Reflux in lap. Gastric Bypass vs. lap. Banded-Gastric Bypass using the A.M.I. Soft Gastric Bypass Band (B-Band.
- Trial name
- NCT01078181
- Testing
- gastric bypass
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Obesity, Type 2 Diabetes Mellitus
Metabolic Surgery Versus Medical Management for Resolution of Type II Diabetes
Best medical management and gastric bypass surgery is a way to treat diabetes as part of regular medical care (standard of care).
- Trial name
- NCT01044602
- Testing
- Laboratory evaluations, sleep study, Best Medical Management, Roux-en-Y gastric bypass surgery
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- David Bradley MD
Pain, Neuropathic, Epilepsy
Cancer in Patients With Gabapentin (GPRD)
High doses of gabapentin are associated with pancreatic acinar cell tumors in rats, but there has been no post marketing pancreatic carcinogenicity signal with gabapentin as reported by spontaneous reports in AERS or in the…
- Conditions
- Pain, Neuropathic, Epilepsy, Renal Pelvis Cancer, Pancreatic Cancer
- Trial name
- NCT01236053
- Testing
- Gabapentin prescriptions
- Volunteers
- 2,323,608 people
- Sponsor
- GlaxoSmithKline
Abdominal Pain
A Pilot Study to Assess the Value of EUS vs EGD in Emergency Room Patients Referred for EGD
Emergency room patients referred for esophago-gastro-duodenoscopy (EGD) often have many possible causes for their symptoms. These inevitably undergo further testing if EGD is inconclusive, which adds costs and inevitably prolongs…
- Trial name
- NCT03432208
- Testing
- GI consult
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Gastroesophageal Reflux, Gastroparesis
Domperidone Expanded Access Protocol for Patients With Gastrointestinal Disorders
FDA currently allows patients 12 years of age and older with various gastrointestinal (GI) conditions to be treated with Domperidone through the Expanded Access to Investigational Drugs program.
- Conditions
- Gastroesophageal Reflux, Gastroparesis, Chronic Constipation With Overflow, Pseudo Obstruction
- Trial name
- NCT02567175
- Testing
- Domperidone
- Where
- United States
- Sponsor
- Prasanna K Kapavarapu
Liver Cirrhosis, Portal Hypertension
Underdilated VCX-TIPS Versus EVL Plus NSBB for Secondary Prophylaxis of Variceal Bleeding in Cirrhosis
Variceal bleeding is a major complication of portal hypertension in patients with cirrhosis and is associated with substantial risks of rebleeding and death.
- Conditions
- Liver Cirrhosis, Portal Hypertension, Gastroesophageal Varices Bleeding, Esophageal Varices
- Trial name
- U-TIPS (NCT07587671)
- Testing
- Underdilated VCX-TIPS, Endoscopic Variceal Ligation, Nonselective Beta-Blockers
- Where
- 3 sites in China
- Volunteers
- 240 people
- Sponsor
- West China Hospital
MASLD
Hepatic Gene Response to Intravenous Glucose in Obese Patients With and Without MASLD Undergoing Bariatric Surgery
The goal of this clinical trial is to learn how the liver responds to sugar in people with obesity who are having bariatric surgery.
- Trial name
- GHAST (NCT07326865)
- Testing
- [6,6-D2]-labeled glucose (intravenous), Saline (0.9% sodium chloride infusion)
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Gastric Cancer, Colorectal Cancer
Effect of Multi-modal Intervention Care on Cachexia in Patients With Advanced Cancer Compared to Conventional Management (MIRACLE)
Background Cancer Cachexia (CC) is a multi-factorial process characterized by progressive weight loss, muscle mass and fat tissue wasting, and adversely affecting their quality of life and survival in patients with advanced stage…
- Conditions
- Gastric Cancer, Colorectal Cancer, Pancreatic Cancer, Biliary Tract Cancer
- Trial name
- MIRACLE (NCT04907864)
- Testing
- Multi-modal intervention
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Kil Yeon Lee
Esophageal Carcinoma, Gastric Cancer (Diagnosis)
Ph II Intraperitoneal Paclitaxel + System Therapy in GI Ca w/Peritoneal Carcinomatosis (STOPGAP-B)
This is a phase II open-label, basket clinical trial to assess the feasibility of systemic and Intraperitoneal chemotherapy in subjects with Gastrointestinal Malignancies with Peritoneal Carcinomatosis.
- Conditions
- Esophageal Carcinoma, Gastric Cancer (Diagnosis), Colorectal Adenocarcinoma, Appendiceal Adenocarcinoma
- Trial name
- NCT07795749
- Testing
- Paclitaxel Q2W, Paclitaxcel Q3W
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of California, Irvine
Gastroparesis
The Use Of Domperidone For The Relief Of Refractory Upper Gastrointestinal GI Symptoms
To prescribe oral domperidone for patients with upper GI symptoms who have failed or suffered adverse effects from standard medical therapy.
- Trial name
- NCT03810287
- Testing
- Domperidone
- Where
- United States
- Sponsor
- Yale University
Gastroparesis
Endoscopic Clips Versus Overstich Suturing System Device for Closure of Mucosotomy After G-POEM
Gastric per-oral endoscopic pyloromyotomy (G-POEM) has been assessed as new modality for treatment of refractory gastroparesis. G-POEM is promising method, which is still under investigation as its safety and efficacy has not…
- Trial name
- NCT03679104
- Testing
- Closure of mucosotomy using endoscopic clips, Closure of mucosotomy using OverStitch™ suturing device
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Gastric Cancer, Leukemia
Effect of Imatinib on Bone Metabolism in Patients With Chronic Myelogenous Leukemia or Gastrointestinal Stromal Tumors
The drug that you are taking for your cancer, imatinib (GleevecTM), has recently been shown to have some new types of side effects. In some people, imatinib can affect how bones are made.
- Conditions
- Gastric Cancer, Leukemia, Chronic Myelogenous Leukemia
- Trial name
- NCT00580281
- Testing
- blood test, urine test, and bone density x-ray.
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Doxorubicin Induced Cardiomyopathy, Breast Cancer
Prevention Using Exercise Rehabilitation to Offset Cardiac Toxicities Induced Via Chemotherapy
The purpose of this study is to identify patients at risk for future heart failure using novel markers of early cardiac damage and determine if exercise training can improve these emerging markers as well as overall fitness and…
- Conditions
- Doxorubicin Induced Cardiomyopathy, Breast Cancer, Gastric Cancer, Leukemia
- Trial name
- HF-PROACTIVE (NCT02796365)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Henry Ford Health System
Gastroparesis
G-POEM vs PEG-J in Gastroparesis Patients
Study design: A randomized non-blinded controlled clinical trial with two study arms (G-POEM and PEG-J). Treatment success is measured using the GCSI at baseline before intervention and six months after intervention with a…
- Trial name
- NCT06372132
- Testing
- G-POEM
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Maastricht University Medical Center
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