Clinical trials: Gastritis, Atrophic
Intestinal Metaplasia
Atrophic Gastritis and OLGIM Stage
Three clinical research coordinators recruited patients aged 40-75 who underwent screening endoscopy at the Digestive Endoscopy Center of Qilu Hospital from July 1, 2022, to July 30, 2024.
- Trial name
- NCT06585553
- Where
- China
- Volunteers
- 2,121 people
- Sponsor
- Shandong University
Atrophic Gastritis, Intestinal Metaplasia
SUrveillance of PREMalignant Stomach - Individualized Endoscopic Follow-up
Introduction: Gastric atrophy and intestinal metaplasia are the principal precursors for gastric cancer and, therefore, are considered gastric premalignant conditions.
- Conditions
- Atrophic Gastritis, Intestinal Metaplasia, Gastric Dysplasia, Gastric Cancer
- Trial name
- SUPREME (NCT04613570)
- Testing
- Upper gastrointestinal endoscopy
- Where
- Portugal
- Volunteers
- 912 people
- Sponsor
- Instituto Portugues de Oncologia, Francisco Gentil, Porto
Chronic Atrophic Gastritis
The Study of Chinese Medicine for the Treatment of Chronic Atrophic Gastritis
The purpose of this study is to evaluate efficacy of Chinese medicine treatment for chronic atrophic gastritis. It is a multi-center, randomized, placebo-controlled trial.
- Trial name
- NCT02955134
- Testing
- Talcid®, Chinese medicine prescription, Compound Azimtamide Entieric-coated Tablets
- Where
- 13 sites in China
- Volunteers
- 468 people
- Sponsor
- Wangjing Hospital, China Academy of Chinese Medical Sciences
Atrophic Gastritis
Natural History, Evolution, and Clinical Features of Autoimmune Atrophic Gastritis
Autoimmune atrophic gastritis (AAG) is an immune-mediated disorder characterized by the loss of oxyntic glands and mucosal atrophy1.Specific autoantibodies directed to gastric parietal cells (PCA) and/or to intrinsic factors are…
- Trial name
- NH-GAA (NCT07388459)
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Chronic Atrophic Gastritis, Depressive Symptoms
Objective Vascular Biomarkers as Triage for Depression in Chronic Atrophic Gastritis
Depressive symptoms are highly prevalent in patients with chronic atrophic gastritis (CAG) but are frequently under-detected due to stigma and reliance on subjective questionnaires.
- Conditions
- Chronic Atrophic Gastritis, Depressive Symptoms, Depression, Gastrointestinal Diseases
- Trial name
- NCT07319338
- Testing
- Vascular-Psychological Triage Workflow
- Where
- 4 sites in China
- Volunteers
- 520 people
- Sponsor
- China Academy of Chinese Medical Sciences
Gastro-Intestinal Disorder, Inflammatory Bowel Diseases
Image-Enhanced Endoscopy in the Gastrointestinal Tract
This study evaluates a range of endoscopic image enhancement techniques for assessing conditions involving the gastrointestinal tract.
- Conditions
- Gastro-Intestinal Disorder, Inflammatory Bowel Diseases, Gastro Esophageal Reflux, Atrophic Gastritis
- Trial name
- NCT04085211
- Where
- United Kingdom
- Volunteers
- 260 people
- Sponsor
- King's College Hospital NHS Trust
Gastritis, Atrophic
L-cysteine Prevents Stomach Exposure to Carcinogenic Acetaldehyde
Atrophic gastritis with hypochlorhydric milieu is a risk factor for gastric cancer. Microbes colonizing the acid-free stomach oxidize ethanol into acetaldehyde, a group 1 carcinogen.
- Trial name
- NCT02524262
- Testing
- Slow-release L-cysteine
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Per Hellström
Chronic Atrophic Gastritis
Clinical Study of Manpixiao in the Treatment of Chronic Atrophic Gastritis
To explore the efficacy and safety of "Manpixiao" in the treatment of Chronic Atrophic Gastritis.
- Trial name
- NCT05493124
- Testing
- Manpixiao, Active comparator
- Where
- 3 sites in China
- Volunteers
- 180 people
- Sponsor
- Beijing University of Chinese Medicine
Helicobacter Pylori Infections, Atrophic Gastritis
Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for Prevention of Gastric Cancer Mortality
Currently no ideal preventive modalities are available for reducing gastric-cancer caused mortality in organized population-based application.
- Conditions
- Helicobacter Pylori Infections, Atrophic Gastritis, Gastric Cancer
- Trial name
- GISTAR (NCT02047994)
- Testing
- Triple therapy
- Where
- Latvia
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Gastric Cancer, Intestinal Metaplasia
New Classification of Stomach Using Probe-based Confocal Laser Endomicroscopy
The aim of the present study was to propose a new pCLE classification of gastric pit patterns and vessel architecture, and to assess the accuracy and interobserver agreement of this new pCLE classification system in the stomach.
- Conditions
- Gastric Cancer, Intestinal Metaplasia, Atrophic Gastritis, Inflammation
- Trial name
- NCT01896310
- Testing
- probe-based confocal laser endomicroscopy
- Where
- China
- Volunteers
- 272 people
- Sponsor
- Shandong University
Gastritis, Atrophic, Helicobacter Pylori Infection
Diagnosis of Gastritis, H. Pylori Infection and Atrophic Gastritis in Dyspeptic Patients
Gastric cancer is the third most common cause of cancer-related death worldwide (1). Upper endoscopy is necessary to detect neoplastic macroscopic features at an early stage, but subtle abnormalities in the gastric mucosa are…
- Conditions
- Gastritis, Atrophic, Helicobacter Pylori Infection, Intestinal Metaplasia, Gastritis
- Trial name
- NCT04296513
- Testing
- High-Definition white light endoscopy., High-definition magnification with digital chromoendoscopy.
- Where
- Ecuador
- Volunteers
- 150 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Chronic Atrophic Gastritis, Hypergastrinemia
YF476 and Type I Gastric Carcinoids (Norway)
The aim of the study is to find out if the experimental medicine, YF476, can make gastric carcinoids, a rare type of stomach tumour, shrink and disappear.
- Conditions
- Chronic Atrophic Gastritis, Hypergastrinemia, Type I Gastric Carcinoids
- Trial name
- NCT01444014
- Testing
- YF476
- Where
- Norway
- Volunteers
- 8 people
- Sponsor
- Trio Medicines Ltd.
Gastritis, Atrophic, Gastric Cancer
System Biology of Spleen Deficiency Syndrome
Spleen Deficiency Syndrome(SDS)is a widely researched issue, but due to the limitations of the research methods, the scientific mechanism of SDS is biased and not comprehensive.
- Trial name
- SBSDS (NCT02915393)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beijing University of Chinese Medicine
Helicobacter Infections
Helicobacter Pylori and Proton Pump Inhibitor
The purpose of this study is to know the distribution of HP in stomach before use of PPI, during use of PPI, and after stop of PPI.
- Trial name
- NCT02449941
- Testing
- PPI (proton pump inhibitor)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Asan Medical Center
Helicobacter Pylori Infection, Atrophic Gastritis
Artificial Intelligence for Determination of Gastroscopy Surveillance Intervals
The purpose of this study is to develop and validate a clinical decision support system based on automated algorithms. This system can use natural language processing to extract data from patients' endoscopic reports and…
- Conditions
- Helicobacter Pylori Infection, Atrophic Gastritis, Intestinal Metaplasia, Low Grade Intraepithelial Neoplasia
- Trial name
- NCT05631015
- Testing
- AI recongnize disease and generate recommendations
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xiuli Zuo
Chronic Atrophic Gastritis (CAG)
Association of Sleep Quality With Pathologic Staging, Acupuncture Treatment in Patients With Chronic Atrophic Gastritis: a Cross-sectional Study
In order to inform clinical treatment decisions and maximize treatment outcomes, this observational study set out to examine the relationship between pathological severity and sleep quality in patients with CAG.
- Trial name
- NCT06912178
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Yi Liang
Gastritis, Helicobacter Pylori Associated Gastritis
New Technology to Differentiate Normal Gastric Mucosa From Helicobacter Pylori Associated Gastritis and Gastric Atrophy
Endoscopy is a tool that has greatly influenced gastroenterological diagnosis. However, conventional endoscopy is limited to detecting lesions on the basis of gross morphological changes and therefore a certainly diagnosis…
- Conditions
- Gastritis, Helicobacter Pylori Associated Gastritis, Atrophic Gastritis
- Trial name
- NCT02597517
- Testing
- Digital chromoendoscopy and magnification
- Where
- Ecuador
- Volunteers
- 72 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Atrophic Gastritis
Usefulness of Serum Pepsinogen and Gastrin as the Predictive Biomarker of Atrophic Gastritis, Intestinal Metaplasia and Gastric Cancer in Korea
It is well-known that atrophic gastritis is a major risk factor for gastric cancer, which leads to variations in the serum levels of gastrin, pepsinogen (PG) I, and PGII.
- Trial name
- NCT02184910
- Testing
- pepsinogen and gastrin
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Gastric Cancer, Dysplasia Stomach
Endoscopic Surveillance on a High-risk Population for Gastric Cancer in Latin America: The ECHOS Cohort Study.
The goal of this observational study is to evaluate the risk factors associated with incident HGD/GA in patients with CAG with or without IM who are enrolled in endoscopic surveillance, as well as to compare GA incidence…
- Conditions
- Gastric Cancer, Dysplasia Stomach, Atrophic Gastritis, Helicobacter Pylori Infection
- Trial name
- ECHOS (NCT05969444)
- Where
- 2 sites in Chile
- Volunteers
- 685 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Intestinal Metaplasia, Gastric Cancer
Gastric Cancer Precursor Lesions (GCPL) Study
Background: Gastric cancer is a leading cause of cancer deaths around the world. This disease is a serious problem in places like East Asia, Central and South America, and Eastern Europe.
- Trial name
- NCT03188406
- Where
- 9 sites in Chile
- Volunteers
- 1,300 people
- Sponsor
- National Cancer Institute (NCI)