Clinical trials: Gastro Intestinal Bleeding
Upper Gastrointestinal Hemorrhage
Risk Scoring Systems in Upper GI-haemorrhage
Use of risk scoring systems in the assessment of patients presenting with upper gastrointestinal haemorrhage is increasing. Comparative studies have intended to identify the system of choice, but the majority of these are…
- Trial name
- NCT01589250
- Where
- Denmark
- Volunteers
- 831 people
- Sponsor
- Odense University Hospital
Gastrointestinal Hemorrhage, Ulcer
Gastroprotective Agent Compliance in Patients at Risk Suffering From a Gastrointestinal(GI) Ulcer
The purpose of this study is to assess gastroprotective agent compliance in patients at risk suffering from a gastrointestinal bleeding ulcer or a symptomatic ulcer with NSAID.
- Trial name
- NCT01215058
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
Obscure Gastrointestinal Bleeding
Preparation Regimens to Improve Capsule Endoscopy Visualization and Diagnostic Yield
Small bowel capsule endoscopy (SBCE) has become an important tool in clinical practice since its introduction in 2000. This non-invasive method allows the visualization of small bowel mucosa, being essential in the management of…
- Trial name
- PrepRICE (NCT05140057)
- Testing
- Moviprep
- Where
- Portugal
- Volunteers
- 210 people
- Sponsor
- Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E.
Risk Factors, Complication of Surgical Procedure
ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care
Observational retrospective study of patients in need of acute surgical care admitted to Skåne University Hospital between 2009 and 2019.
- Conditions
- Risk Factors, Complication of Surgical Procedure, Complication of Treatment, Complication of Anesthesia
- Trial name
- ACUTE (NCT05195697)
- Testing
- Observational study of different treatments and time to treatment
- Where
- Sweden
- Volunteers
- 3,000 people
- Sponsor
- Region Skane
Upper Gastrointestinal Bleeding
HDUPE 2004: Gastro-Oesophageal Haemorrhage in Emergency : Gastric Préparation to Endoscopy
Gastric lavage is usually used for gastric preparation before endoscopy in patients with upper gastrointestinal bleeding. However, the benefit-risk balance of putting a nasogastric tube in these patients is not clearly defined.
- Trial name
- NCT00259220
- Testing
- erythomycin, gastric lavage alone, erythromycine and gastric lavage
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lower GI Bleeding
Safe Discharge in Lower Gastrointestinal Bleeding
The increasing incidence in lower gastrointestinal bleeding (LGIB) leads to a rise in hospital admission. Many LGBI are self-limiting thus the several scores to identify low risk patients suited to outpatient care have been…
- Trial name
- NCT06409988
- Testing
- Safe discharge
- Where
- Spain
- Volunteers
- 398 people
- Sponsor
- Germans Trias i Pujol Hospital
Upper Gastrointestinal Bleeding
Efficacy Test of Real-Time Upper Gastrointestinal Monitoring System
A monitoring system was developed for detecting upper gastrointestinal (UGI) rebleeding. This system consists of (1) a tiny endoscopy, (2) a wearable device, and (3) a software.
- Trial name
- NCT03680950
- Testing
- Upper Gastrointestinal Monitoring System
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Cheng-Kung University Hospital
Fissure in Ano, Rectal Diseases
Diltiazem Ointment With Lidocaine vs. Nifedipine Ointment With Lidocaine Ointment for Treatment of Chronic Anal Fissure
Anal fissure is a common anorectal diseases characterized by tear of the anoderm from the dentate line to the anal verge leading to pain and bleeding during and post defecation.
- Conditions
- Fissure in Ano, Rectal Diseases, Rectal Bleed
- Trial name
- NCT04887818
- Testing
- 2% Diltiazem ointment with 1.5% lidocaine, 0.3% Nifedipine ointment with 1.5% lidocaine
- Where
- Canada
- Volunteers
- 430 people
- Sponsor
- University of Calgary
Stress Ulcer Prophylaxis
Stress Ulcer Prophylaxis of Intravenous Esomeprazole in Chinese Seriously Ill Patients
The efficacy of esomeprazole will be compared versus cimetidine (a drug that previously demonstrated prevention of bleeding events) during treatment period in proportion of patients for the prevention of upper GI bleeding.
- Trial name
- SUP (NCT02157376)
- Testing
- Esomeprazole, Cimetidine
- Where
- 15 sites in China
- Volunteers
- 343 people
- Sponsor
- AstraZeneca
Esophageal Varices in Cirrhosis of the Liver, Upper Gastrointestinal Bleeding
Endoscopic Variceal Ligation in Children
This is an ambispective single-center cohort study of pediatric patients with portal hypertension and esophageal varices. The study was designed to evaluate the efficacy and safety of primary prophylaxis with endoscopic variceal…
- Conditions
- Esophageal Varices in Cirrhosis of the Liver, Upper Gastrointestinal Bleeding, Endoscopy, Child
- Trial name
- NCT03943784
- Testing
- Endoscopic Variceal Ligation, Non-Selective Beta-Blocking Agent
- Volunteers
- 60 people
- Sponsor
- Hospital Vall d'Hebron
Capsule Endoscopes
Evaluation of Obscure Gastrointestinal Bleeding Patients With Conventional Capsule Endoscopy and Panoramic Side View Capsule Endoscopy
With the development of endoscopy, patients with suspected gastrointestinal tract disease can be evaluated with further management.
- Trial name
- NCT04568343
- Testing
- Capsule endoscopy
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
GastroIntestinal Bleeding, Anemia
Iron Supplementation in Upper Non-variceal Gastrointestinal Bleeding
Anemia is a frequent complication of gastrointestinal bleeding, affecting 61% of the patients. Currently, anemia caused by gastrointestinal bleeding can be treated with iron supplementation.
- Trial name
- FIERCE (NCT05060731)
- Testing
- Oral iron supplementation, Intravenous iron supplementation
- Where
- Hungary
- Volunteers
- 570 people
- Sponsor
- University of Pecs
Upper Gastrointestinal Bleeding
Trial of Hemospray Plus Epinephrine Injection Versus Endoscopic Hemoclip
The non-variceal upper gastrointestinal bleeding is defined as gastrointestinal bleeding located proximal to the angle of Treitz, whose cause is not related to esophagogastric varices or gastropathy of portal hypertension.
- Trial name
- NCT02537353
- Testing
- Metal clips, Hemospray, Endoscopy Exam
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Hepatocellular Carcinoma, Esophageal Varix
Prophylactic Endoscopic Variceal Ligation in Patients With High-risk Esophageal Varices Receiving Atezo/Bev for HCC
The goal of this study is to evaluate whether prophylactic endoscopic variceal ligation (EVL) can prevent esophageal variceal bleeding in patients with hepatocellular carcinoma (HCC) receiving atezolizumab and bevacizumab…
- Conditions
- Hepatocellular Carcinoma, Esophageal Varix, Bleeding Esophageal Varices
- Trial name
- ESCOAT (NCT06819566)
- Testing
- Endoscopic variceal ligation (EVL)
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Asan Medical Center
Rectal Prolapse
A Modified Technique to Facilitate Pealing of the Rectal Mucosa in Delorme Operation
The aim of this study is to evaluate the investigator new modification for delorme procedure in patients with rectal prolapse , assessing intra-operative morbidity and recurrence rate .
- Trial name
- NCT02901210
- Testing
- Modified delorme procedure
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yasser Mohamed Abdel-samii
Gastrointestinal Vascular Malformation
the Efficiency of Thalidomide for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation
Gastrointestinal vascular malformation (GIVM), which is an important cause of acute or chronic gastrointestinal bleeding, currently lacks of effective treatment.
- Trial name
- NCT02707484
- Testing
- Thalidomide (100mg), Thalidomide (50mg)
- Where
- 10 sites in China
- Volunteers
- 150 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Precancerous Condition
Risk Factors for Barrett's Esophagus in Patients With BE, Gastroesophageal Reflux, or Gastrointestinal Bleeding
RATIONALE: A study that evaluates DNA changes and other disease-related health information in patients with Barrett's esophagus, gastroesophageal reflux, or gastrointestinal bleeding may help doctors learn more about the risk…
- Trial name
- NCT00445653
- Where
- 2 sites in United States
- Volunteers
- 170 people
- Sponsor
- Massachusetts General Hospital
Atmospheric Pressure; Adverse Effect, GastroIntestinal Bleeding
Gastrointestinal Bleeding and Atmospheric Pressure Relationship
This study aims to investigate whether atmospheric pressure has an effect on upper gastrointestinal bleeding (UGIB), which includes causes such as peptic ulcer disease, esophagitis, gastritis, gastrointestinal varices…
- Trial name
- NCT06515353
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Saglik Bilimleri Universitesi
Peptic Ulcer, Hemorrhage
Rapid Urease Test for Diagnosis of H. Pylori Infection in Patients With Peptic Ulcer Bleeding
Rapid urease test (RUT) is the most commonly used biopsy-based method to diagnose Helicobacter pylori (Hp) infection because of its simple, rapid and accurate characters.
- Trial name
- NCT01282853
- Testing
- endoscopic biopsy
- Where
- Taiwan
- Volunteers
- 116 people
- Sponsor
- Far Eastern Memorial Hospital
Peptic Ulcer Bleeding
Risk Factors of Rebleeding After Peptic Ulcer Bleeding: a Nationwide Cohort Study
The purpose of the investigators study is to investigate the factors associated with rebleeding in patients with peptic ulcer bleeding.
- Trial name
- KPUB (NCT02152904)
- Where
- South Korea
- Volunteers
- 892 people
- Sponsor
- Joon Sung Kim