Clinical trials: Gastroenteritis Acute
Acute Appendicitis
Changes in the Treatment of Acute Appendicitis
The purpose of this study was to analyse the epidemiology, diagnostics, the type of surgical techniques and their development over time, and mortality in acute appendicitis in 68 hospitals in Germany based on routine data between…
- Trial name
- TreatApp (NCT06558760)
- Volunteers
- 31,988 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Acute Appendicitis, Postoperative Pain
Intravenous Lidocaine in Children Undergoing Laparoscopic Appendectomy
Intravenous lidocaine - a potent local anesthetic with analgesic and anti-inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management…
- Conditions
- Acute Appendicitis, Postoperative Pain, Postoperative Nausea and Vomiting
- Trial name
- NCT03886896
- Testing
- Lidocaine
- Where
- Poland
- Volunteers
- 74 people
- Sponsor
- Medical University of Warsaw
Appendicitis
Morphine Analgesia in Patients With Acute Appendicitis
The purpose of the study is to evaluate morphine effect on pain reduction and diagnostic accuracy in patients admitted to emergency ward with the diagnosis of acute appendicitis.
- Trial name
- NCT00477061
- Testing
- Morphine
- Where
- Iran
- Volunteers
- 71 people
- Sponsor
- Tehran University of Medical Sciences
Acute Appendicitis
MANAGEMENT OF APPENDICITIS DURING THE COVID-19 PANDEMIC
During the Covid-19 pandemic, non-operative management for acute appendicitis (AA) was implemented in the UK. The aim of this study was to determine the efficacy and outcomes of conservative versus surgical management of AA…
- Trial name
- observational (NCT04615728)
- Testing
- laparoscopic or open appendicectomy
- Where
- United Kingdom
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Kidney Transplant; Complications, Diarrhoea;Acute
GastroIntestinal Panel in Kidney Transplant Patients
This project focuses on the evaluation of the impact of the rapid mutltiplex test on changes in anti-infectious treatments in kidney transplant patients with diarrhea.
- Conditions
- Kidney Transplant; Complications, Diarrhoea;Acute, Diarrhea Infectious
- Trial name
- GIPIK (NCT05722119)
- Testing
- FilmArray GI
- Volunteers
- 135 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ulcerative Colitis
User Surveillance in Ulcerative Colitis
The aim of the non-interventional study is to document the daily doses in acute and remission therapy, the frequence of doses (1, 2, 3 or 4 times daily), when rectal dosage forms are added and, when and how long steroids are…
- Trial name
- CARE (NCT01363453)
- Where
- 105 sites in Germany
- Volunteers
- 500 people
- Sponsor
- Ferring Pharmaceuticals
Appendicitis Acute, Appendicitis
Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis
This will be an explorative, proof-of-principle, open, multi-center investigation. The investigation aims to investigate the safety of the PERIsign system and the ability of physicians to differentiate between healthy individuals…
- Conditions
- Appendicitis Acute, Appendicitis, Abdominal Pain, Peritonitis
- Trial name
- PeriSaFe01 (NCT06296953)
- Testing
- PERIsign examination
- Where
- 2 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- STB INN AB
Radiation Toxicity, Esophagitis
Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis
Purpose：To observe and evaluate the clinical efficacy and safety of deep-sea fish oil in preventing acute radiation-induced esophagitis (ARIE).
- Conditions
- Radiation Toxicity, Esophagitis, Esophageal Cancer
- Trial name
- NCT06392971
- Testing
- Deep-sea fish oil
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Chengdu Medical College
Appendicitis Acute
Low-dose Contrast Media for Low-kVp Abdomen CT
The purpose of this clinical study is to test the performance of low radiation dose abdominal CT combined with low dose contrast media for the diagnosis of acute appendicitis in young patients.
- Trial name
- NCT05878665
- Testing
- Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Bohyun Kim
Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA)
German Spondyloarthritis Inception Cohort
The German Spondyloarthritis Inception cohort (GESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in Germany on patients with early SpA including ankylosing spondylitis (AS, also known as…
- Conditions
- Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA), Axial Psoriatic Arthritis (axPsA), Acute Anterior Uveitis (AAU)
- Trial name
- GESPIC (NCT01277419)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Charite University, Berlin, Germany
Appendicitis
Diagnostic Value of Procalcitonin in Patients With Acute Appendicitis
The values of laboratory examinations which are useful for the diagnoses of acute appendicitis are white blood cell count (WBC), C-reactive protein (CRP) and erythrocyte blood sedimentation rate (ESR).
- Trial name
- NCT00630071
- Where
- Germany
- Volunteers
- 103 people
- Sponsor
- Ruhr University of Bochum
Acute Appendicitis
Acute Appendicitis and Microbiota - Etiology of Appendicitis and Antibiotic Therapy Effects
Appendicectomy has been the treatment of acute appendicitis for over a hundred years. Appendicectomy, however, includes operative and postoperative risks despite being a routine procedure.
- Trial name
- MAPPAC (NCT03257423)
- Testing
- Ertapenem followed by levofloxacin and metronidazole, Moxifloxacin, Appendectomy
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Turku University Hospital
Appendicitis, Appendicitis Acute
a Retrospective Observational Study Comparing Outcomes of Retrocaecal Appendicitis With Non-retrocaecal Appendicitis
A retrospective observational study investigating whether retrocecal appendicitis associated with worse operative and postoperative outcomes than non-retrocecal appendicitis.
- Conditions
- Appendicitis, Appendicitis Acute, Retrocecal Appendicitis
- Trial name
- NCT05315869
- Testing
- Appendectomy
- Where
- Czechia
- Volunteers
- 754 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Acute Uncomplicated Appendicitis
Direct Visualization ERAT Versus Laparoscopic Appendectomy in Adults With Acute Uncomplicated Appendicitis
This study compares two ways of treating acute uncomplicated appendicitis, which is a mild form of appendicitis. In the Direct Visualization ERAT group, participants will receive Endoscopic Retrograde Appendicitis Therapy (ERAT).
- Trial name
- E-APPEND (NCT07230379)
- Testing
- Direct Visualization Endoscopic Retrograde Appendicitis Therapy, Laparoscopic appendectomy
- Where
- 14 sites in China
- Volunteers
- 376 people
- Sponsor
- Changhai Hospital
Acute Appendicitis
Preoperative Immature Granulocyte Count and Percentage for Acute Appendisitis
Appendectomy is the most effective treatment option for acute appendisitis, which is the most commen emergent surgical pathology. However with in time period, surgical treatment borders are narrowed.
- Trial name
- NCT04440150
- Testing
- Appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Gastroenteritis
Clinical Trial to Investigate the Efficacy and Safety of Ondansetron (Danset - Adwia) Versus Placebo Plus the Standard of Care in the Treatment of Nausea and Vomiting in Adult Patients With Acute Gastroenteritis
A Randomized, Open-label, Active-Controlled Clinical Trial to Investigate the Efficacy and Safety of Ondansetron compared to Metoclopramide in the management of Nausea and Vomiting in Adult Patients with Acute Gastroenteritis.
- Trial name
- NCT05876585
- Testing
- Ondansetron 8 mg ampoule, Metoclopramide 10 mg ampoule
- Volunteers
- 126 people
- Sponsor
- Genuine Research Center, Egypt
Ulcerative Colitis (UC), Acute Severe Ulcerative Colitis
Effectiveness and Safety of Upadacitinib for Acute Severe Ulcerative Colitis
The aim of this retrospective observational study is to investigate and compare the real-world effectiveness and safety of upadacitinib when used as first-line exposure versus rescue exposure in patients with acute severe…
- Conditions
- Ulcerative Colitis (UC), Acute Severe Ulcerative Colitis, Upadacitinib
- Trial name
- NCT07472309
- Testing
- Upadacitinib
- Where
- China
- Volunteers
- 81 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Acute Complicated Appendicitis With Diffuse Peritonitis
Laparoscopic Versus Open Appendectomy Plus Peritoneal Lavage for Acute Complicated Appendicitis Patients With Diffuse Peritonitis
This study aim to evaluate the efficacy and safety of laparoscopic versus open appendectomy in the treatment of acute complicated appendicitis with diffuse peritonitis.
- Trial name
- NCT06633744
- Volunteers
- 60 people
- Sponsor
- Shanghai Zhongshan Hospital
Acute Appendicitis, Acute Abdomen
Transversus Abdominis Plane Block in Acute Appendicitis Pain Managment
In this study, it was aimed to investigate the analgesic efficacy of the preoperatively applied Transversus Abdominis Plane (TAP) Block in the management of acute appendicitis-related abdominal pain and post-appendectomy pain.
- Conditions
- Acute Appendicitis, Acute Abdomen, Postoperative Pain
- Trial name
- NCT05004532
- Volunteers
- 22 people
- Sponsor
- Erol Olcok Corum Training and Research Hospital