Clinical trials: Gastroenterology
Ulcerative Colitis
Care Path for the Management of Ulcerative Colitis
Assess if standardized care-path that features objective evaluations of disease activity and time-bound algorithms is superior to usual step-care in the treatment of ulcerative colitis.
- Trial name
- CONSTRUCT (NCT01882426)
- Testing
- Enhanced treatment algorithm, Usual Care
- Volunteers
- 192 people
- Sponsor
- University of Western Ontario, Canada
Crohn's Disease
Trial of a Treatment Algorithm for the Management of Crohn's Disease
Assess if the implementation of a treatment algorithm will improve the management of Crohn's disease (CD) in comparison to usual care based gastroenterology practices.
- Trial name
- REACT (NCT01030809)
- Testing
- Treatment Algorithm for Crohn's Disease
- Where
- Canada
- Volunteers
- 1,999 people
- Sponsor
- University of Western Ontario, Canada
Depressive Symptoms, Major Depressive Disorder
Digital Therapeutic for Adolescent Depressive Symptoms in Cardiology and Gastroenterology
The primary aim of this pilot study is to assess the feasibility, acceptability, and preliminary evidence of efficacy of a self-guided, cognitive behavioral therapy (CBT)-based mobile app intervention (SparkRx) for symptoms of…
- Conditions
- Depressive Symptoms, Major Depressive Disorder, Depression, Cardiology
- Trial name
- NCT05461599
- Testing
- SparkRx Mobile App
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Limbix Health, Inc.
Gastroparesis
13C-Spirulina Nitrogen Content GEBT Study
The purpose of this study is to determine whether there is a difference in the human in vivo response to 13C-Spirulina meals manufactured using 13C-Spirulina containing different levels of protein (as measured by %nitrogen).
- Trial name
- NCT04635306
- Testing
- Approved GEBT test meal
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairn Diagnostics
HELICOBACTER PYLORI INFECTIONS
Feasibility Study to Diagnose Helicobacter Pylori in the Paediatric Population Using Non-invasive Fecal Analysis
Helicobacter pylori infection is a widespread bacterial disease affecting nearly half of the world's population. In children, the infection displays distinct features versus adults, with lower prevalence, variable symptoms, and…
- Trial name
- HEPYCA (NCT07083804)
- Testing
- Gastric biopsies, Stool sampling
- Where
- France
- Volunteers
- 188 people
- Sponsor
- Poitiers University Hospital
Gastroenterology, LARS - Low Anterior Resection Syndrome
A Randomised Clinical Investigation to Assess Efficacy of Low Volume Transanal Irrigation by Qufora® IrriSedo MiniGo Versus Conservative Treatment for Low Anterior Resection Syndrome Patients
The purpose of this post-market clinical follow up study is to assess the efficacy on clinical symptoms of LARS of low volume Transanal Irrigation by MiniGo in conjunction with conservative treatment versus conservative treatment…
- Conditions
- Gastroenterology, LARS - Low Anterior Resection Syndrome, Rectal Cancer
- Trial name
- MINIGO (NCT06923150)
- Where
- 9 sites in France
- Volunteers
- 78 people
- Sponsor
- Qufora A/S
Constipation
Guideline to Implementation: A Rapid Clinical Care Pathway to Care for Patients Affected by Chronic Constipation
The study is being completed to test the pilot implementation of a rapid clinical care pathway for chronic constipation in the University of Michigan Gastroenterology clinic.
- Trial name
- NCT06352827
- Testing
- Survey
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Michigan
Gastroenterology Surgery, Tube Feeding
Efficacy of a Novel Prototype Gastrostomy Tube Anchor Dressing
This is a single-center prospective study evaluating the efficacy of a prototype gastrostomy anchor dressing for use with button gastrostomy tubes.
- Trial name
- Tube Anchor (NCT07115134)
- Testing
- Bearables Gastrostomy Tube Dressing
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Children's National Research Institute
Patient Diagnosed or Treated for Granulomatous Hepatitis Followed in the Internal Medicine (and or) Hepato-gastroenterology Departments
Lyon Granulomatous Hepatitis Study
Granulomatous hepatitis are histopathologically defined by the presence of epithelioid and gigantocellular granulomas within the hepatic parenchyma. Hepatic granulomas are observed in 2 to 15% of liver biopsies.
- Trial name
- LGH (NCT04459897)
- Testing
- Evaluation of epithelioid and gigantocellular granulomas within the hepatic parenchyma by histopathology approach.
- Where
- 3 sites in France
- Volunteers
- 600 people
- Sponsor
- Hospices Civils de Lyon
Crohn's Disease
Calprotectin-Directed Humira® Maintenance Therapy (CADHUM)
This is a study that invites adults with Crohn's disease and have been responding well to Adalimumab (Humira ®) for at least 6 months.
- Trial name
- CADHUM (NCT01674413)
- Testing
- Adalimumab, Adalimumab PRN
- Where
- United States
- Sponsor
- Peter Higgins
Colonoscopy
Impact of Digital Tools on the Quality of Bowel Preparation for Colonoscopy
This is a single blinded randomized controlled study. The main question of this study is whether better preparation by making full use of digital tools can increase patient compliance with the preparation methods for colonoscopy…
- Trial name
- NCT05734079
- Testing
- Standard of care, Standard of care + Video call, Standard of care + Video call + Educational video film
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Cardiology, Gastroenterology
Applying the Intention-Action Framework to Specialty Referrals
This is a prospective randomized controlled trial evaluating an EHR-embedded behavioral intervention intended to reduce low-value specialty referrals in cardiology, pulmonology, and gastroenterology.
- Conditions
- Cardiology, Gastroenterology, Pulmonology
- Trial name
- NCT07671976
- Testing
- Information provision, Auditing, Checklist
- Where
- United States
- Volunteers
- 1,600 people
- Sponsor
- University of California, Los Angeles
Fatty Liver
The Effect of Pentoxifylline on Liver Function Tests in Fatty Liver Disease
This randomized double blind clinical trial was performed in patients with non-alcoholic fatty liver disease.They were randomly assigned to lifestyle modification alone or lifestyle modification plus Pentoxifylline groups.
- Trial name
- NCT02283710
- Testing
- Pentoxifylline, Lifestyle modification
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Tehran University of Medical Sciences
Disordered Eating
Investigating Prevalence of Disordered Eating in Children With GI Disorders
Gastroenterological disorders are disorders affecting the stomach, intestines and associated organs. Symptoms of these types of disorders vary but often include vomiting, diarrhoea, weight loss and loss of appetite.
- Trial name
- NCT01872169
- Testing
- Disordered eating screening questionnaire
- Where
- United Kingdom
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
GERD
Asociación Española de Gastroenterologia (Spanish Gastroenterology Association) Gastroesophageal Reflux Disease Guideline - Prospective Study
To evaluate symptomatic outcome and HRQoL in GERD patients treated following a new CP Guideline.
- Trial name
- Prospect (NCT00697008)
- Where
- 29 sites in Spain
- Volunteers
- 300 people
- Sponsor
- AstraZeneca
Helicobacter Pylori Infection
Intraluminal Mono-antibiotic Therapy for Helicobacter Pylori Infection - A Comparison of Levofloxacin Powder and Levofloxacin Solution
Helicobacter pylori (H. pylori) is an important causal factor of chronic gastritis, peptic ulcer disease, gastric cancer and gastric lymphoma. The World Health Organization classified H. pylori as a Group 1 carcinogen in 1994.
- Trial name
- NCT03832465
- Testing
- Levofloxacin film-coated tablet, Levofloxacin intravenous solution
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Mackay Memorial Hospital
Infantile Colic
Lactobacillus Reuteri Supplementation in the Treatment of Infantile Colic
The purpose of this study is to evaluate the efficacy of the oral administration of Lactobacillus reuteri in treating infantile colic as defined by the Rome III criteria.
- Trial name
- PROBIOC (NCT01887444)
- Testing
- Lactobacillus reuteri DSM17938 probiotic
- Where
- France
- Sponsor
- BioGaia AB
Colorectal Cancer
Efficacy of a Mobile Clinical Decision Support System (CaPtyVa CCR App) to Improve Performance of Gastroenterology and Coloproctology Specialists in Colorectal Cancer Screening and Surveillance According to Guideline Recommendations: A Randomized Clinical Trial.
This prospective study evaluates the use of a (Mobile Decision Support Systems), MDSS (CaPtyVa CCR app) in order to improves gastroenterology and coloproctology specialist's performance in CRC screening and surveillance according…
- Trial name
- NCT04389502
- Testing
- CaPtyVa app, Control group
- Where
- Argentina
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital Aleman
Gastrointestinal Diseases
The Clinical Impact and Outcomes of Interventional Endoscopy Procedures
The main purpose of the protocol is to collect and evaluate performance data after patients undergoing various interventional endoscopy procedures performed at H. H. Chao Comprehensive Digestive Disease Center (CDDC).
- Trial name
- NCT01492231
- Where
- United States
- Volunteers
- 3,500 people
- Sponsor
- University of California, Irvine
Colonic Polyp
Use of the Napoleon to Improve Polyp Measurement in Gastroenterology Fellows
This is a clinical trial assessing gastroenterology fellows' accuracy of colonic polyp measurement using a Micro-Tech Endoscopic Polyp Measurement Device named Napoleon.
- Trial name
- NCT04858477
- Testing
- Visual estimation of polyp size, Napoleon measurement of polyp size
- Where
- 4 sites in United States
- Volunteers
- 46 people
- Sponsor
- NYU Langone Health