Clinical trials: Gastroesophageal Reflux
Gastroesophageal Reflux Disease
Transoral Incisionless Fundoplication Database Repository (TIF)
Collect data on individuals who have a transoral incisionless fundoplication (TIF) performed by physicians at Indiana University for the treatment of gastroesophageal reflux disease.
- Trial name
- TIF (NCT04306380)
- Testing
- no intervention, database study
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Indiana University
Barrett Esophagus
Barrett's Esophagus in Patients with GERD
To assess the prevalence and characteristics of BE in patients suffering of chronic GERD symptoms
- Trial name
- NCT06897540
- Testing
- Upper endoscopy
- Volunteers
- 70 people
- Sponsor
- Assiut University
Gastroesophageal Reflux Disease
Safety and Quality of Life Study of Dexlansoprazole Modified Release Formulation to Treat Heartburn
The purpose of this study is to determine the long-term safety profile of daily treatment with dexlansoprazole MR in subjects with gastroesophageal reflux disease.
- Trial name
- NCT00255190
- Testing
- Dexlansoprazole MR
- Where
- 181 sites in United States
- Volunteers
- 591 people
- Sponsor
- Takeda
Gastroesophageal Reflux Disease, Non-erosive Reflux Disease
The CONQUEST-Study. Evaluation of Clinical Endpoints for Treatment-induced Changes in GERD-related Symptoms (BY1023/NL511)
The aim of the study is to compare two different endpoint measures: heartburn as assessed by the physicians versus gastroesophageal reflux disease (GERD)-related symptoms as assessed by the patient using the ReQuest™…
- Trial name
- NCT00449813
- Testing
- Pantoprazole
- Where
- 15 sites in Netherlands, Switzerland
- Volunteers
- 40 people
- Sponsor
- Takeda
Non-erosive Reflux Disease, Diarrhea-Predominant Irritable Bowel Syndrome
Efficacy and Safety of WPQW Granule for Overlap of NERD and IBS-D
Non-erosive reflux disease（NERD）and Diarrhea-Predominant Irritable Bowel Syndrome（IBS-D）are both the common refractory gastrointestinal diseases.
- Trial name
- NCT05369884
- Testing
- WPQW granule, WPQW granule simulant
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Gastroesophageal Reflux, Apnea
Impact of Swaddle Blanket on Gastroesophageal Reflux
Gastroesophageal reflux disease (GERD) has been reported in up to 85% of all infants born prematurely, and has been associated with a wide range of symptoms.
- Conditions
- Gastroesophageal Reflux, Apnea, Bradycardia, Oxygen Desaturations
- Trial name
- NCT02083952
- Testing
- Swaddle Blanket
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Valley Health System
Gastroesophageal Reflux Disease
PREA, PK And Safety PASS Study Of IV Pantoprazole In Pediatric Subjects
The purpose of this study is to characterize the pharmacokinetics (PK) and safety of intravenous (IV) pantoprazole in patients 1 to 16 years old who are candidates for acid suppression therapy.
- Trial name
- NCT02401035
- Testing
- IV pantoprazole
- Where
- 19 sites in United States, Argentina and 7 more
- Volunteers
- 19 people
- Sponsor
- Pfizer
Gastroesophageal Reflux Disease (GERD)
Performance and Safety of Afluxin® in Patients With Gastroesophageal Reflux Disease
Gastroesophageal Reflux Disease (GERD) is a chronic condition in which stomach acid flows back into the esophagus, causing irritation and inflammation.
- Trial name
- ARMOR (NCT06984484)
- Testing
- Afluxin®
- Where
- 7 sites in Italy
- Volunteers
- 208 people
- Sponsor
- Devintec Sagl
GERD, Gastroesophageal Reflux
Compassionate Use of Domperidone for Refractory Gastroparesis
The purpose of this program is to allow the use of domperidone in children from 12 to 21 years of age with symptoms related to motility disorders and Gastroesophageal reflux disease (GERD) who have failed all the standard…
- Conditions
- GERD, Gastroesophageal Reflux, Gastroparesis
- Trial name
- NCT04699591
- Testing
- Domperidone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Jose Cocjin
Mitral Valve (MV) Regurgitation
ACCESS-Europe A Two-Phase Observational Study of the MitraClip® System in Europe
The MitraClip System enables the European physicians an alternative therapeutic option for patients with mitral regurgitation (MR).
- Trial name
- ACCESS-EU (NCT01288976)
- Testing
- MitraClip, Medical Management, Mitral Valve Surgery
- Where
- Germany
- Volunteers
- 721 people
- Sponsor
- Abbott Medical Devices
Esophageal Motility Disorders
Effect of Esophageal Contractile Reserve on Changes in Esophageal Motility and Symptoms After ARS in Patients With GERD
rapid swallow (MRS) can assess the contractile reserve capacity of the oesophageal body and identify and diagnose oesophageal motility disorders, but the impact of preoperative oesophageal reserve capacity on postoperative…
- Trial name
- NCT05380791
- Testing
- Follow-up visits
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Shandong University
Asthma, Lung Diseases
Study of Acid Reflux in Asthma
The purpose of this study is to determine if subjects with symptomatic asthma who are assigned to treatment with a proton pump inhibitor (PPI) drug such as Nexium have fewer asthma attacks than similar subjects assigned to…
- Conditions
- Asthma, Lung Diseases, Lung Diseases, Obstructive
- Trial name
- NCT00069823
- Testing
- Esomeprazole
- Where
- 20 sites in United States
- Volunteers
- 403 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
GERD
Truncal Vagotomy in Patients Undergoing Revisional Sleeve Gastrectomy to Gastric Bypass
The purpose of this study is to investigate the efficacy of performing a truncal vagotomy along with a sleeve to bypass revision surgery in reducing the severity and/or incidence of gastroesophageal reflux disease (GERD)…
- Trial name
- NCT04901429
- Testing
- Truncal vagotomy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Baylor Research Institute
Gastroesophageal Reflux
Randomized Trial for Pharmacogenomics-based Proton Pump Inhibitor Therapy in Children
Proton pump inhibitors are administered to children as off-label use in Japan. The purpose of this study is to evaluate the effects of CYP2C19 genotypes on pharmacokinetic /pharmacodynamic profiles of PPI in children.
- Trial name
- NCT00299845
- Testing
- Lansoprazole
- Where
- Japan
- Sponsor
- Osaka University
Varicose Veins, Venous Reflux
Pelvic Embolisation to Reduce Recurrent Varicose Veins - Primary
The aim of this study is to identify whether the treatment of pelvic venous reflux (pelvic coil embolisaton) in females with leg varicose veins, who have a proven contribution to their leg varicose veins from pelvic reflux, have…
- Trial name
- NCT01901731
- Testing
- transjugular coil embolisation of pelvic veins, endovenous treatment of leg varicose veins
- Where
- 2 sites in United Kingdom
- Volunteers
- 270 people
- Sponsor
- The Whiteley Clinic
Feeding Tube
Self-Propelled Versus Standard Percutaneous Endoscopic Gastrojejunostomy(PEG-J); RCT
Our main hypothesis is that self-propelled Percutaneous Endoscopic Gastrojejunostomy tube (PEG-J) that has a balloon on it's tip is associated with lower J-tube retrograde migration rate, and lower rates of short- and long-term…
- Trial name
- NCT01892267
- Testing
- PEG-J placement
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Johns Hopkins University
Gastroesophageal Reflux Disease
An Evaluation of the Medtronic Gatekeeper System in the Treatment of SUBJECTS With Gastroesophageal Reflux Disease (GERD)
The purpose of the study is to demonstrate the intended use of the Gatekeeper Reflux Repair System to provide symptomatic relief is subjects with gastroesophageal reflux disease.
- Trial name
- NCT00200044
- Testing
- Gatekeeper Reflux Repair System
- Where
- 11 sites in United States, Netherlands
- Volunteers
- 143 people
- Sponsor
- MedtronicNeuro
GERD
Clinical Trial to Assess the PK/PD of YYD601 20mg After Oral Administration if Healthy Adult Subjects (Phase1)
Clinical Trial to Assess the PK/PD of YYD601 20mg After Oral Administration if Healthy Adult Subjects (Phase1)
- Trial name
- NCT03985319
- Testing
- YYD601 20mg, Nexium tab 20mg
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Exercise Triggered Asthma, Gastroesophageal Reflux
Effect of Acid Reflux on Respiratory Physiology During Exercise in Athletes With GER-Response to Acid Suppression
We propose that acid reflux affects respiratory dynamics (breathing) in patients who are exercising and that athletes improve their exercise capacity with acid suppression therapy.
- Trial name
- NCT00444236
- Testing
- Nexium
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Utah
Bladder Tumour, Prostate Hyperplasia
Clasic Laryngeal Mask Airway(C-LMA) and I-gel Releated Regurgitation and Complications
1. i-gel 2. C-LMA Compare the effect on gastroeosephageal reflux Postoperative complicatios.
- Trial name
- C-LMA (NCT01876836)
- Testing
- i-gel, C-LMA
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.