Clinical trials: Gastroesophageal Reflux
Helicobacter Pylori Infection, Peptic Ulcer
The Revolutions of Helicobacter Pylori Infection, Bacterial Density, and Histological Features After Antrectomy
Helicobacter pylori (HP) is a gram-negative bacillus responsible for one of the most common infections found in humans worldwide.
- Conditions
- Helicobacter Pylori Infection, Peptic Ulcer, Bile Reflux, Gastritis
- Trial name
- NCT00441831
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- Mackay Memorial Hospital
Non-erosive Reflux Disease
A Multi-center, Randomized, Double-blind, Parallel-group, Placebo Controlled Phase III Study to Evaluate the Efficacy and Safety of LXI-15028 in Non-erosive Reflux Disease in Chinese Patients for 4 Weeks
This is one multi-center, randomized, double-blind, parallel-group, placebo controlled Phase III clinical study to evaluate the efficacy and safety of LXI-15028 50 mg in treatment of non-erosive reflux disease in Chinese patients…
- Trial name
- NCT03591653
- Testing
- LXI-15028
- Where
- China
- Volunteers
- 291 people
- Sponsor
- Shandong Luoxin Pharmaceutical Group Stock Co., Ltd.
Aortic Aneurysm, Abdominal, Popliteal Artery Aneurysm
Venous Distension in Patients With Aneurysmatic Arterial Disease
The aim of the study is to assess if venous distension in patients with aneurysmatic arteriopathy is higher compared to patients with peripheral arterial occlusive disease (PAOD) and in controls.
- Conditions
- Aortic Aneurysm, Abdominal, Popliteal Artery Aneurysm, Peripheral Arterial Occlusive Disease, Vascular Diseases
- Trial name
- NCT02867501
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Baselland Bruderholz
Pulmonary Aspiration of Gastric Contents
SMART Study (Sellick's Maneuver Assisted Real Time) to Deliver Target Cricoid Pressure in Simulated Environment
Cricoid force is applied during airway management to prevent pulmonary aspiration of regurgitated gastric contents. This force is usually applied by a nurse or anaesthesia assistant.
- Trial name
- NCT02749175
- Testing
- Cricoid force sensor monitor system
- Where
- Singapore
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Barrett's Esophagus, Gastroesophageal Reflux
Evaluation of MicroRNA Expression in Blood and Cytology for Detecting Barrett's Esophagus and Associated Neoplasia
The primary purpose of this study is to test new methods to diagnose BE in time before it turns into advanced cancer. Once BE is diagnosed, the current standard of care is to monitor the disease so that complication such as…
- Conditions
- Barrett's Esophagus, Gastroesophageal Reflux, Esophageal Adenocarcinoma
- Trial name
- NCT02464930
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Midwest Biomedical Research
Obesity
Long Term Results After Sleeve Gastrectomy
Today sleeve gastrectomy is the most performed bariatric procedure worldwide. Since 2005 it is gaining popularity as a single procedure. Long term data is scarce.
- Trial name
- NCT02947412
- Testing
- laparoscopic sleeve gastrectomy
- Volunteers
- 40 people
- Sponsor
- Sana Klinikum Offenbach
Gastroesophageal Reflux Disease
Nasopharyngeal 24 Hour pH Monitoring in Health Adult Volunteers
Involves a 24-hour pH probe study using the Dx-pH Measurement System on patients who do not have symptoms of laryngopharyngeal reflux or gastroesophageal reflux disease to establish normal values for the Dx-pH Measurement System.
- Trial name
- NCT00584675
- Testing
- Dx-pH Measurement Probe
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Gastroesophageal Reflux
Gastroesophageal Reflux During LMA in Control Ventilation (LMA, Laryngeal Mask Airway)
Laryngeal mask airway is seldom used for control ventilation in America, while it is popular in China. The question is whether the incidence of gastroesophageal reflux in control ventilation is really higher than in spontaneous…
- Trial name
- LMA (NCT02441257)
- Testing
- control ventilation, spontaneous ventilation
- Volunteers
- 200 people
- Sponsor
- Zhenmeng Wang
GERD, Barrett's Esophagus
A Feasibility Study of Confocal Microendoscopy in the Evaluation of Gastrointestinal Neoplasia -Project 1
The overall objective of this study is to obtain data to evaluate whether high-resolution imaging of the gastrointestinal mucosain vivo can assist clinicians in detecting dysplastic (precancerous) areas.
- Trial name
- NCT01384695
- Testing
- Fluorescein, Proflavine hemisulfate
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Anandasabapathy, Sharmila, M.D.
Cough, Cerebellar Ataxia
Chronic Cough and CANVAS (Cerebellar Ataxia With Neuropathy and Bilateral Vestibular Areflexia Syndrome)
Chronic cough is a frequent cause of Pneumology consultations. CANVAS syndrome (Cerebellar Ataxia with Neuropathy and bilateral Vestibular Areflexia Syndrome) is a progressive and disabling neurological disease that very…
- Conditions
- Cough, Cerebellar Ataxia, Gastroesophageal Reflux
- Trial name
- CANVAS (NCT04703595)
- Testing
- To determine the presence of biallelic expansion of AAGGG in RFC1 in patients with chronic cough, regardless of the presence of neurological symptoms.
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
GERD, Sleeve Gastrectomy
An Investigation of Electrical Stimulation on Gastroesophageal Reflux Disease (GERD) in Patients After Sleeve Gastrectomy
Sleeve gastrectomy (SG) has gained popularity as both a staged and a definitive procedure for morbid obesity due to its technical simplicity, low-morbidity and excellent results both for weight loss and control of metabolic…
- Trial name
- NCT02210975
- Testing
- LES-Stimulation Device
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Maastricht University Medical Center
End Stage Renal Failure on Dialysis
Argyle Safety Fistula Cannula With Anti-reflux Valve Clinical Study
The purpose of the investigation is to confirm the safety and performance of the Argyle™ Safety Fistula Cannula with Anti-reflux Valve for hemodialysis treatment.
- Trial name
- NCT05927532
- Testing
- Argyle Safety Fistula Cannula with Anti-Reflux Valve
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Mozarc Medical US LLC
Gastro -Oesophagal Reflux, Laryngo-pharyngeal Reflux
European TIF2.0 Registry
This is a European, multi-centre, prospective registry that aims to determine the safety and efficacy of transoral incisionless fundoplication, with or without concomitant hiatal hernia repair, for the treatment of patients with…
- Trial name
- EURO-TIF (NCT07395219)
- Testing
- Transoral incisionless fundoplication with or without concomitant hiatal hernia repair with the EsophyX device
- Where
- 7 sites in Austria, Italy and 5 more
- Volunteers
- 500 people
- Sponsor
- Cleveland Clinic London
Urine Reflux, Kidney Damage
(ARFI) Shear Velocity Imaging of the Kidneys in Pediatric Patients
Urine reflux (urine backing up into the kidneys) is common in the pediatric population and may be complicated by renal abnormalities, such as infection and scarring.
- Trial name
- NCT01781819
- Testing
- ARFI SVI Ultrasound Imaging
- Where
- United States
- Sponsor
- University of Michigan
Bladder Tumour, Prostate Hyperplasia
Clasic Laryngeal Mask Airway(C-LMA) and I-gel Releated Regurgitation and Complications
1. i-gel 2. C-LMA Compare the effect on gastroeosephageal reflux Postoperative complicatios.
- Trial name
- C-LMA (NCT01876836)
- Testing
- i-gel, C-LMA
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
GERD
Symptom Assessment in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) or enGERD (Endoscopic-negative GERD) After Treatment With Pantoprazole (BY1023/M3-343)
The aim of this study is to compare investigator and patient-assessed gastroesophageal reflux disease symptoms in patients with erosive GERD or endoscopic-negative GERD (enGERD).
- Trial name
- NCT00336219
- Testing
- Pantoprazole
- Where
- 40 sites in Australia, Austria and 2 more
- Volunteers
- 628 people
- Sponsor
- Takeda
GERD
Impact of GERD on Daily Life (NIS)
The aim of this study is to gather epidemiological data in a population of GERD patients in primary care with a history of erosive esophagitis (less than or equal to 3 years).
- Trial name
- Alegria (NCT00545883)
- Where
- 112 sites in Belgium
- Volunteers
- 2,001 people
- Sponsor
- AstraZeneca
Gastroesophageal Reflux Disease
Comparison of Laparoscopic Nissen Versus Thal Fundoplication in Children
Laparoscopic fundoplication is increasingly performed in paediatric surgery. Many types of fundoplication are performed, each has advantages and disadvantages.
- Trial name
- NCT01027975
- Testing
- laparoscopic Nissen/laparoscopic Thal
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust
Chest Pain, Gastroesophageal Reflux
Chest Pain Pilot Study
The purpose of this study is to compare the efficacy of Nexium® with placebo in relief of acid related pain or discomfort in the chest.
- Trial name
- NCT00251901
- Testing
- Esomeprazole
- Where
- 80 sites in Canada, Denmark and 4 more
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Esophagitis, Reflux, Esophagitis, Peptic
Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis
This is a study to assess the efficacy and safety of 8 weeks of treatment with Dexlansoprazole modified release (MR)(60 mg daily and 90 mg daily) compared to Lansoprazole (30 mg daily) in healing subjects with endoscopically…
- Trial name
- NCT00251719
- Testing
- Dexlansoprazole MR, Lansoprazole
- Where
- 144 sites in United States, Australia and 14 more
- Volunteers
- 2,054 people
- Sponsor
- Takeda
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