Clinical trials: Gastrointestinal Bleed
Schistosomiasis Mansoni, Portal Hypertension
Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or Surgery
Upper gastrointestinal bleeding (UGIB) is a major cause of morbidity and mortality in patients with portal hypertension secondary to schistosomiasis mansoni.
- Conditions
- Schistosomiasis Mansoni, Portal Hypertension, Upper Gastrointestinal Bleeding
- Trial name
- NCT01931826
- Testing
- Endoscopic treatment, Total EGDS+ endoscopy
- Where
- Brazil
- Volunteers
- 54 people
- Sponsor
- Universidade Estadual de Ciências da Saúde de Alagoas
Liver Cirrhosis, Esophageal and Gastric Varices
The Effect of Carvedilol VS Endoscopic Therapy in Primary Prophylaxis of High-risk Esophageal Gastric Variceal Bleeding
To compare the efficacy and safety of Carvedilol and endoscopic therapy in Primary Prophylaxis of High-risk Esophageal Gastric Variceal Bleeding.
- Trial name
- NCT02695732
- Testing
- Carvedilol, endoscopy
- Where
- China
- Volunteers
- 792 people
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Occlusion/Thrombosis, Peptic Ulcer Hemorrhage
Systematic Screening for Risk-factors for Ulcer Bleeding Before Anti-thrombotic Treatment
In a prospective randomised study design to investigate, if a systematic risk factor screening for bleeding ulcer in patients, who following percutaneous coronary intervention (PCI) commence a one year combination treatment with…
- Trial name
- NCT01447498
- Testing
- Screening for risk factors for ulcer bleeding
- Where
- Denmark
- Volunteers
- 2,024 people
- Sponsor
- Odense University Hospital
Upper Gastrointestinal Bleeding
Hemostatic Powder Following Injection Therapy Versus Conventional Dual Therapy for Endoscopic Hemostasis for Non-variceal Upper Gastrointestinal Bleeding
Acute upper gastrointestinal hemorrhage (UGIH) is a common condition that leads to hospital admission, and has significant associated morbidity and mortality, especially in the elderly.
- Trial name
- NCT02717416
- Testing
- Endo-Clot, hemoclip or electrical coagulation
- Where
- South Korea
- Volunteers
- 226 people
- Sponsor
- Yonsei University
Aspirin, GastroIntestinal Bleeding
When Should Low-dose Aspirin be Resumed After Peptic Ulcer Bleeding?
Acute upper gastrointestinal (GI) bleeding associated with the use of low-dose aspirin (ASA) is a major cause of peptic ulcer bleeding worldwide.
- Trial name
- NCT03785015
- Testing
- Resume Aspirin within 12 hours, Resume Aspirin 72 - 84 hours
- Where
- Hong Kong
- Volunteers
- 436 people
- Sponsor
- Chinese University of Hong Kong
Rectal Bleeding
Colonic Capsule Endoscopy (CCE) for Screening of Neoplasm's A Pilot Study
The primary aim is to evaluate the efficiency of capsule endoscopy (CCE) in in the detection of neoplasms compared to conventional colonoscopy in persons participating in the Danish screening program for colorectal cancer with a…
- Trial name
- NCT02303756
- Testing
- Pillcam® COLON Capsule
- Where
- Denmark
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hematemesis, Portal Hypertension
Comparing Two Methods to Stop Vomiting of Blood Using the Endoscope
Band ligation and injection sclerotherapy are two modalities of treatment that are applied using the endoscope. The purpose of this study is to determine which of two methods is better for controlling bleeding from the upper gut.
- Trial name
- NCT01131962
- Testing
- Endoscopic control of hematemesis
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- University of Alexandria
Lower Gastrointestinal Bleeding, Small Bowel Bleeding
Urgent Panendoscopy in Patients Presenting With Hematochezia
Gastrointestinal bleeding is a significant emergency condition requiring prompt diagnosis. Current evidence presents a clinical paradox: urgent colonoscopy (within 24 hours) shows no clear benefit in several studies, while urgent…
- Trial name
- NCT06985277
- Testing
- Urgent endoscopy strategy, Standard colonoscopy with standard VCE group
- Where
- Thailand
- Volunteers
- 188 people
- Sponsor
- Mahidol University
Liver Cirrhosis, Esophageal Varices Bleeding
Effect of Re-education on Rebleeding Rate After Endoscopic Treatment in Liver Cirrhosis
A prospective, randomized controlled study on whether re-education after discharge can reduce the rebleeding rate after endoscopic treatment of esophageal and gastric varices in patients with liver cirrhosis
- Conditions
- Liver Cirrhosis, Esophageal Varices Bleeding, Gastric Variceal Bleeding, Bleeding
- Trial name
- NCT05302661
- Testing
- re-education
- Where
- China
- Volunteers
- 508 people
- Sponsor
- Qilu Hospital of Shandong University
Blood, Injection, Injury Type Phobia, Gastrointestinal Ulcer Haemorrhage
Comparative Study of Autologous Blood Injection Versus Diluted Epinephrine in Treating Actively Bleeding Gastroduodenal Ulcers
Endoscopic injection of autologous blood can control bleeding from gastroduodenal ulcers.
- Conditions
- Blood, Injection, Injury Type Phobia, Gastrointestinal Ulcer Haemorrhage, Adverse Reaction to Epinephrine
- Trial name
- NCT01560702
- Testing
- Epinephrine, Blood
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Peptic Ulcer Bleeding
Study to Evaluate Efficacy and Safety of Wound Dressing Solution Containing EGF in Patients With Peptic Ulcers Bleeding
This is a prospective, single-blinded, randomized study to evaluate the efficacy and safety of CEGP003 in patients with acute peptic ulcers bleeding, compared to endoscopic epinephrine injection therapy.
- Trial name
- CEGP003 (NCT03469167)
- Testing
- CEGP003, Injection Tx
- Volunteers
- 76 people
- Sponsor
- CGBio Inc.
Gastrointestinal Bleeding
Occult Obscure Gastrointestinal Bleeding
To test the activity of a polyglucosamine (PG) together with a Standard Management protocol (SM) on the occult and obscure gastrointestinal bleeding (OGIB) and the clinical symptoms in patients suffering from colonic…
- Trial name
- OGIB (NCT03464539)
- Testing
- PG low molecular weight chitosan
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Blymum Srl
GastroIntestinal Bleeding
High-Volume Vs Low-Volume Preparation in Emergency Department
The primary endpoint of this study was to compare the intestinal cleansing of patients with LGIB requiring colonoscopy, prepared with High-Volume or with Low-Volume who have to perform colonoscopy, directly from the ED.
- Trial name
- NCT05362227
- Testing
- Low volume macrogol, High volume macrogol
- Where
- Italy
- Volunteers
- 228 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rectal Prolapse
A Modified Technique to Facilitate Pealing of the Rectal Mucosa in Delorme Operation
The aim of this study is to evaluate the investigator new modification for delorme procedure in patients with rectal prolapse , assessing intra-operative morbidity and recurrence rate .
- Trial name
- NCT02901210
- Testing
- Modified delorme procedure
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yasser Mohamed Abdel-samii
Case-report, Diagnosis
Diagnosis and Clinical Presentation of Iliac Graft-Enteric Fistula: A Case Report
Abstract Introduction: Aorto-enteric fistula (AEF) is a life-threatening complication arising from abnormal connections between the gastrointestinal tract and major arteries.
- Conditions
- Case-report, Diagnosis, Digestive System Fistula, Gastrointestinal Hemorrhage
- Trial name
- NCT06553105
- Testing
- ct scan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Golestan University of Medical sciences
Colitis, Ischemic
Study of Ischemic Colitis Compared to Other Diagnoses in Patients With Lower Gastrointestinal Bleeding
The purpose of this study is to study the demographic,laboratory,endoscopic, and outcomes of ischemic colitis patient presented with severe lower gastrointestinal bleeding compared to other diagnoses.
- Trial name
- NCT01078324
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- University of California, Los Angeles
GI-bleeding
Emergency Capsule Endoscopy in Severe GI-bleeding
Primary objective: Evaluation of capsule endoscopy in the emergency setting of severe GI-Bleeding.
- Trial name
- NCT01584869
- Testing
- capsule endoscopy
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
CIRRHOSIS, ESOPHAGEAL VARICES
PROPRANOLOL PLUS LIGATION REDUCES RECURRENCE OF ESOPHAGEAL VARICES?
This prospective randomized controlled trial will compare endoscopic band ligation (EBL) with propranolol and EBL alone in primary prophylaxis of variceal bleeding among cirrhotic patients with high-risk varices.
- Trial name
- NCT01893541
- Testing
- ENDOSCOPIC BAND LIGATION, PROPRANOLOL, a multiband ligation device
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of São Paulo
Radiotherapy, Radiation Proctitis
Dietary Supplements to Treat Radiation-Induced Rectal Injury
This clinical study is a prospective, single-arm, single-center trial aimed at assessing the safety and efficacy of tributyrin (TB) as dietary supplements in the treatment of chronic radiation-induced rectal injury (RRI).
- Trial name
- NCT06776016
- Testing
- Butyrate
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Upper GI Bleeding
Presence or Absence of Blood in the GI Lumen
Bleedings in the upper digestive tract are common. Usually, laboratory and clinical parameters are considered to establish a suspicion for a bleeding in the digestive tract and to estimate urgency of the situation.
- Trial name
- NCT05415124
- Testing
- HemoPill, Endoscopy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health