Clinical trials: Gastrointestinal Bleed
Peptic Ulcers
Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer
The present study will compare the hemostasis-maintaining effects of intravenous omeprazole and ranitidine in patients with upper gastrointestinal hemorrhage that have undergone endoscopic hemostasis, to establish which…
- Trial name
- NCT00247130
- Testing
- Omeprazole, Ranitidine
- Where
- Japan
- Sponsor
- Keio University
Lower Gastrointestinal Bleeding, Diverticular Bleeding
Clinical Trial to Evaluate the Efficacy and Safety of Nexpowder™ for Diverticular Bleeding in the Lower Gastrointestinal Tract
Clinical Trial to Evaluate the Efficacy and Safety of Nexpowder™ for Diverticular Bleeding in the Lower Gastrointestinal Tract
- Trial name
- NCT06939907
- Testing
- Nexpowder™
- Where
- 6 sites in South Korea
- Volunteers
- 60 people
- Sponsor
- Next Biomedical Co., Ltd.
Acute Upper Gastrointestinal Bleeding, Upper Gastrointestinal Bleeding
Trimebutine Maleate for Enhancing Gastric Visualization in Acute Upper Gastrointestinal Bleeding
Acute upper gastrointestinal bleeding is a medical emergency that requires an urgent upper endoscopy to locate and treat the source of the bleeding.
- Conditions
- Acute Upper Gastrointestinal Bleeding, Upper Gastrointestinal Bleeding, Gastrointestinal Hemorrhage
- Trial name
- NCT07749300
- Testing
- Trimebutine Maleate
- Volunteers
- 100 people
- Sponsor
- Assiut University
Venous Thromboembolism, Esophagus Cancer
Venous Thromboembolism and Bleeding Risk in Patients With Esophageal Cancer
This study aims to assess the 6- and 12-month venous thromboembolism (VTE) and bleeding incidence from the start of cancer diagnosis in a retrospective cohort of patients with esophageal cancer.
- Conditions
- Venous Thromboembolism, Esophagus Cancer, Bleeding, Chemotherapy Effect
- Trial name
- VENETIA (NCT03646409)
- Testing
- Venous thromboembolic event, arterial thromboembolic event, bleeding events
- Where
- Netherlands
- Volunteers
- 542 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Periampullary Cancer, Pancreatic Fistula
Complication of Pancreatic Fistula and Bleeding After Pancreaticoduodenectomy in Treatment Periampullary Cancer
This multi-site study will be done across Hepatobiliary and Pancreatic Surgery Department at Cho Ray Hospital and University and Pharmacy Center.
- Conditions
- Periampullary Cancer, Pancreatic Fistula, Bleeding
- Trial name
- PF (NCT04985071)
- Testing
- Pancreaticoduodenectomy
- Where
- Vietnam
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Vo Truong Quoc
Colorectal Cancer, Diverticulitis
Anastomotic Bleeding in Colorectal Anastomosis Relating to the Placement of the Stapler Spike to the Staple Line
Each colorectal anastomosis is routinely evaluated intraoperatively by sigmoidoscopy and, in the presence of signs of bleeding, also postoperatively (persistent rectal bleeding within 24 hours after surgery).
- Trial name
- NCT07506005
- Where
- Austria
- Volunteers
- 102 people
- Sponsor
- Kepler University Hospital
STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI
HELicobacter Pylori Screening in Patients With Acute Myocardial Infarction Pilot Study
The aim of this study is to determine the prevalence of Helicobacter pylori (Hp) infection in patients with myocardial infarction (MI).
- Trial name
- HELPpilot (NCT04289012)
- Testing
- Helicobacter Pylori screening by UBT
- Where
- 2 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Karolinska Institutet
Malignancy, Metastasis
Same-session MR-only Simulation and Treatment With MRI-guided Adaptive Palliative RadioTherapy
This proposed study is unique in that patients will not undergo computed tomography (CT) simulation at any point during their treatment course and will instead have same-session magnetic resonance (MR)-only simulation and…
- Conditions
- Malignancy, Metastasis, Hemoptysis, Gastrointestinal Bleeding
- Trial name
- MAP-RT (NCT03824366)
- Testing
- Volumetric MR imaging, Radiation therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Liver Cirrhosis, Variceal Haemorrhage
Early Use of TIPSS in Patients With Cirrhosis and Variceal Bleeding
Gastro-oesophageal varices (swollen veins in the gullet and stomach) are present in 50% of patients with liver cirrhosis and are its most serious complication as their rupture results in potentially life threatening bleeding.
- Trial name
- EarlyTIPSS (NCT02377141)
- Testing
- Endoscopic Variceal Band Ligation, Transjugular Intrahepatic Porto-Systemic Stent Shunt
- Where
- 2 sites in United Kingdom
- Volunteers
- 59 people
- Sponsor
- University of Edinburgh
Upper GI Bleeding
Analysis the Vocs in Upper GI Bleeding Patients
This project aims to collect the exhaled breath of patients with acute upper gastrointestinal bleeding clinically, divide them into large, small and no bleeding groups according to the results of gastroscopy, analyze the…
- Trial name
- NCT05457062
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Liver Cirrhosis
Long-term Efficacy and Safety of LSD Versus TIPS for Cirrhotic Portal Hypertension Bleeding and Hypersplenism
This study aims to compare two treatments for cirrhotic portal hypertension with acute esophagogastric variceal bleeding and hypersplenism: laparoscopic splenectomy and azygoportal disconnection (LSD) and transjugular…
- Trial name
- LSD、TIPS (NCT07490405)
- Testing
- LSD, TIPS
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Northern Jiangsu People's Hospital
Peptic Ulcer/Erosions
Famotidine Compared With Pantoprazole to Prevent Recurrent Aspirin-Induced Peptic Ulcer/Erosion
Low-dose aspirin can prevent cerebral and cardiovascular accidents in individuals with symptomatic atherothrombotic disease, but its use is frequently limited by gastrointestinal side effects.
- Trial name
- NCT00843063
- Testing
- pantoprazole vs famotidine
- Where
- China
- Volunteers
- 161 people
- Sponsor
- Ruttonjee Hospital
Gastroesophageal Varices Hemorrhage
Color Doppler US and TE as Predictors for Presence of Gastroesophageal Varices and Variceal Bleeding in Patients With LC
The aim of the study is to evaluate the ability of Doppler ultrasonography of the portal vein and liver stiffness measurement using Transient Elestoghraphy in predicting prescence of gastroesophageal variceal and variceal…
- Trial name
- NCT05891184
- Testing
- color doppler ultrasound, transient elastography, upper endoscopy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Gastrectomy for Gastric Cancer, Gastric Cancer
AI-assisted Decision-making of Reoperation for Postoperative Bleeding of Gastric Cancer
The goal of this observational study is to develop and validate a deep learning model to dynamically assess postoperative bleeding risk and assist in decision-making for re-operation in adult patients (≥18 years) diagnosed with…
- Trial name
- NCT07525765
- Where
- China
- Volunteers
- 7,000 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Abdominal Pain, Inflammatory Bowel Diseases
Examining the Effect of Ondansetron on Bowel Prep Success
This is a pilot randomized-controlled trial assessing the utility of ondansetron for improving pediatric pre-colonoscopy bowel prep outcomes using the boston bowel preparation score, as well as assessing the impact on patient…
- Conditions
- Abdominal Pain, Inflammatory Bowel Diseases, Eosinophilic Gastroenteritis, Diarrhea
- Trial name
- NCT05439772
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- State University of New York - Downstate Medical Center
Gastrointestinal Hemorrhage, Gastrointestinal Neoplasms
Hemostatic Powder Versus Clinical Management for the Treatment of Upper Gastrointestinal Bleeding From Tumor Lesions
This study evaluates the efficacy of the endoscopic hemostatic powder for the treatment of bleeding from malignant lesions of the upper GI tract.
- Trial name
- NCT02820077
- Testing
- Hemospray (Endoscopic treatment with hemostatic powder)
- Volunteers
- 62 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Gastric Varix, Sepsis
Antibiotic Prophylaxis in Patients Undergoing GVO
We design a randomized trial to clarify the necessity of antibiotic prophylaxis for the patients chronic liver disease with gastric varices treated by elective GVO.
- Conditions
- Gastric Varix, Sepsis, Liver Cirrhoses, Fever
- Trial name
- ABX-GV (NCT04140578)
- Testing
- Ertapenem
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Liver Cirrhosis
A Comparative Evaluation of TEG Versus ROTEM for Coagulopathy Correction
Studies comparing Thromboelastography or Rotational thromboelastometry versus standard coagulation tests are abundant. Data comparing the two exclusively in a liver intensive care set up is limited.
- Trial name
- NCT05333510
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Upper Gastrointestinal Bleeding
HDUPE 2004: Gastro-Oesophageal Haemorrhage in Emergency : Gastric Préparation to Endoscopy
Gastric lavage is usually used for gastric preparation before endoscopy in patients with upper gastrointestinal bleeding. However, the benefit-risk balance of putting a nasogastric tube in these patients is not clearly defined.
- Trial name
- NCT00259220
- Testing
- erythomycin, gastric lavage alone, erythromycine and gastric lavage
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Iron Deficiency Anemia, Endoscopy
Endoscopic Findings in Iron Deficiency Anemia: A Cross-Sectional Study From Port Sudan
Background: Iron deficiency anemia (IDA) is a common condition often linked to gastrointestinal blood loss, making endoscopic evaluation essential for identifying underlying causes.
- Conditions
- Iron Deficiency Anemia, Endoscopy, Anemia
- Trial name
- IDA (NCT07143435)
- Where
- Sudan
- Volunteers
- 117 people
- Sponsor
- National Center for Gastroentestinal and Liver Disease