Clinical trials: Gastrointestinal Bleed
Bleeding After GI Endoscopy
Endoscopic Application of Hemostatic Drug Powder in Lower Gastrointestinal Bleeding: A Pilot Study
This clinical trial will enroll patients at National Cheng Kung University Hospital. All patients who are hospitalized for lower gastrointestinal bleeding and undergo colonoscopy will be invited to participate.
- Trial name
- NCT07679139
- Testing
- Tranexamic acid and sucralfate powder spray, Standard endsocopic hemostasis
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Peptic Ulcer
Natural History of Non-steroidal Anti-inflammatory Drug and Non-Helicobacter Pylori in Bleeding Peptic Ulcers
The aim of this study is to study the natural history of the ulcer healing while on proton pump inhibitors (PPI) and the ulcer recurrence without acid suppression therapy of Non-steroidal Anti-inflammatory Drugs (NSAID)…
- Trial name
- NCT00153712
- Where
- China
- Volunteers
- 391 people
- Sponsor
- Chinese University of Hong Kong
Upper Gastrointestinal Bleeding
Side Effects of Transesophageal Echocardiography
Transesophageal echocardiography is commonly used during cardiac surgery. Complications of transesophageal echocardiography are rare (1,2%), but are often underestimated and can lead to unrecognized blood loss and site of…
- Trial name
- NCT03432559
- Testing
- endoscopy
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Vienna
Gastrointestinal Hemorrhage
Evaluation the Performance of Given Diagnostic System in Detection of Bleeding Events in the Small Bowel
Obscure gastrointestinal bleeding (OGIB) has been one of the most challenging area in the field of gastroenterology, as small bowel is beyond the reach of ordinary endoscopes like oesophagogastroduodenoscopy (OGD) and…
- Trial name
- NCT01441219
- Testing
- Colon 2
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Chinese University of Hong Kong
Diverticular Bleeding
Early Routine Bowel Preparation for Suspected Acute Diverticular Bleeding
This investigation will utilize both a five-year retrospective analysis and a two-year prospective investigation. Variables including age; gender; presence of anticoagulation medication; hospital length of stay; total transfused…
- Trial name
- NCT05170945
- Testing
- Early bowel preparation for colonoscopy
- Where
- United States
- Volunteers
- 415 people
- Sponsor
- Methodist Health System
Polyp of Colon, Gastrointestinal Bleeding
Polypectomy With Hot vs Cold Snare in Small Colonic Lesions
Colonoscopy is the technique of choice for the diagnosis and prevention of colorectal cancer (CRC). The identification and extirpation of adenomas decreases the incidence of CRC by up to 76%.
- Conditions
- Polyp of Colon, Gastrointestinal Bleeding, Colonic Adenoma
- Trial name
- Polypech-c (NCT03783156)
- Testing
- hot snare, cold snare
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital del Rio Hortega
Small Bowel Obstruction, Gastrointestinal Hemorrhage
Nasogastric/Orogastric Tube Placement Verification Study Using RightSpot pH Indicator to Verify Gastric Acidity
This study will evaluate the use of RightBio Metrics' RightSpot device used to determine if there is proper placement of a nasogastric or orogastric tube.
- Trial name
- NCT01561729
- Testing
- RightSpot pH Indicator, Chest radiograph
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- RightBio Metrics
Liver Cirrhosis, Esophageal Varices
Two-dimensional Shear-Wave Elastography Evaluate Esophageal Varices Bleeding Risk of Liver Cirrhosis
The purpose of this retrospective study was to investigate the diagnostic performance of 2D-SWE for predicting the presence of esophageal varices and high-risk varices in patients with liver cirrhosis.
- Conditions
- Liver Cirrhosis, Esophageal Varices, Liver Stiffness
- Trial name
- NCT03989973
- Testing
- Gastroscopy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- West China Hospital
Non-variceal Upper Gastrointestinal Bleeding
Keverprazan vs Pantoprazole for the Treatment of ANVUGIB
Acute non-variceal upper gastrointestinal bleeding (ANVUGIB) is a common medical emergency requiring hospitalization. The cornerstone of ANVUGIB management is effective gastric acid suppression.
- Trial name
- NCT07776730
- Testing
- Pantoprazole, Keverprazan
- Where
- China
- Volunteers
- 908 people
- Sponsor
- General Hospital of Shenyang Military Region
Portal Hypertension, Cirrhosis
MRI to Assess the Effect of Non-selective Beta-blocker in Patients With Cirrhosis
Background: Standardization and new therapeutic treatments of variceal bleeding has significantly reduced the mortality the last 25 years, but there is still a high 6-week mortality around 15-20% and 1-year mortality of about…
- Conditions
- Portal Hypertension, Cirrhosis, Esophageal Varices, Gastric Varices Bleeding
- Trial name
- NCT03438916
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Hvidovre University Hospital
Cirrhosis, Portal Vein Thrombosis
Safety of Anticoagulant Therapy After Endoscopic Treatment
The investigators aimed to verify the efficacy and safety of nadroparin calcium warfarin sequential (NWS) anticoagulation therapy after endoscopic therapy in PVT patients with cirrhosis and AVB.
- Conditions
- Cirrhosis, Portal Vein Thrombosis, Esophageal and Gastric Varices, Anticoagulant-induced Bleeding
- Trial name
- NCT04976543
- Testing
- nadroparin calcium-warfarin sequential anticoagulation
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Qilu Hospital of Shandong University
Colorectal Cancer, Rectal Bleeding
Desmopressin (DDAVP) in Patients With Colorectal Cancer and Rectal Bleeding
The objective of this study is to find the maximum tolerated dose and preliminary efficacy of desmopressin as an haemostatic agent, when is administered to patients with colorectal cancer and rectal bleeding, before specific…
- Trial name
- NCT01623206
- Testing
- Desmopressin
- Where
- 2 sites in Argentina
- Volunteers
- 30 people
- Sponsor
- Laboratorio Elea Phoenix S.A.
Liver Cirrhosis, Portal Hypertension Related to Cirrhosis
Colonic Polypectomy in Cirrhotic Patients With Portal Hypertension
The goal of this retrospective cohort study is to evaluate the risk of post-polypectomy bleeding following the colonoscopy resection of lower gastrointestinal polyps in patients with liver cirrhosis with portal hypertension.
- Conditions
- Liver Cirrhosis, Portal Hypertension Related to Cirrhosis, Polyp of Colon, Polypectomy
- Trial name
- NCT06832826
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Upper Gastrointestinal Bleeding
Efficacy Test of Real-Time Upper Gastrointestinal Monitoring System
A monitoring system was developed for detecting upper gastrointestinal (UGI) rebleeding. This system consists of (1) a tiny endoscopy, (2) a wearable device, and (3) a software.
- Trial name
- NCT03680950
- Testing
- Upper Gastrointestinal Monitoring System
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Cheng-Kung University Hospital
Variceal Bleeding
Efficacy and Safety of Intravenous Vitamin K1 in Management of Acute Variceal Bleeding
The administration of Vitamin K1 (Vit-K1) injection is frequently utilized in clinical practice for managing upper gastrointestinal bleeding (UGIB) associated with liver cirrhosis, despite insufficient evidence supporting its…
- Trial name
- NCT06839352
- Testing
- Vitamin K1
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Zagazig University
Intraventricular Hemorrhage, Pulmonary Hemorrhage
Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correlation With Severe Morbidity and Mortality
This study aims to understand the role of extracellular vesicles (EVs) in extremely premature infants, those born before 28 weeks of gestation.
- Conditions
- Intraventricular Hemorrhage, Pulmonary Hemorrhage, Death, ELGAN (22-28SA)
- Trial name
- VEEP (NCT07273643)
- Testing
- Venous Cord blood sample, Arterial cord blood sample
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Montpellier
Henoch-Schönlein Purpura, Gastrointestinal Injury
Mycophenolate Mofetil in Gastrointestinal Henoch-Schonlein Purpura
Henoch Schönlein purpura (HSP) is the most common type of vasculitis in children, with an incidence of ~10/100,000, whereas >90% of the patients develop symptoms at <10 years of age.
- Conditions
- Henoch-Schönlein Purpura, Gastrointestinal Injury, Mycophenolate Mofetil
- Trial name
- NCT05951517
- Testing
- MMF
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Upper GI Bleeding, Bleeds Gastric
Metoclopramide in Upper Gastrointestinal Bleed
The goal of this clinical trial is to test if metoclopramide can improve effectiveness of endoscopic intervention in upper gastrointestinal (GI) bleeds.
- Conditions
- Upper GI Bleeding, Bleeds Gastric, Bleed Ulcer, Hemorrhage Gastric
- Trial name
- NCT05746377
- Testing
- Metoclopramide 10mg, Saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mercy Health System
Early Gastric Adenocarcinoma, Adenocarcinoma, Tubular
Effects of Oral Rabeprazole on the Prevention of Ulcer Bleeding Following Endoscopic Mucosal Resection
The purpose of this study is: To examine if oral administration of Pariet (proton pump inhibitor, 20mg tablets, twice daily for 5 days) before Endoscopic mucosal resection(EMR) exhibits preventive effects of ulcer bleeding…
- Trial name
- NCT00844675
- Testing
- rabeprazole
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- The Catholic University of Korea
Rectal Cancer
Hypofractionated Palliative Radiotherapy in Patients With Advanced Non-operable Rectal Cancer
Many patients with rectal cancer were not candidates for surgical resection because advanced age, comorbidities, or multiple synchronous metastases.
- Trial name
- NCT03853733
- Testing
- rectal cancer radiotherapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Consorci Sanitari de Terrassa