Clinical trials: Gastrointestinal Disorder, Functional
IBS - Irritable Bowel Syndrome
Ethosuximide and Pentoxifylline in the Treatment of Abdominal Pain Related to Irritable Bowel Syndrome
Ethosuximide and pentoxifylline in the treatment of abdominal pain related to irritable bowel syndrome
- Trial name
- NCT04217733
- Testing
- pentoxyifylline, Mebeverine, ethosuximide
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Chronic Hepatitis B
Effect of Telbivudine on Renal Function and Proteinuria in Patients With CHB & Chronic Renal Diseases
Chronic kidney disease (CKD) and chronic viral hepatitis due to hepatitis B virus (HBV) are both major public health problems. Treatment of chronic HBV infection in CKD patients, however, is not well defined because of…
- Trial name
- NCT02049736
- Testing
- Telbivudine
- Where
- Hong Kong
- Sponsor
- Chinese University of Hong Kong
Irritable Bowel Syndrome
Saccharomyces Cerevisiae for Irritable Bowel Syndrome
This study is designed to see the response of saccharomyces cerevisiae for symptomatic improvement of patients with IBS
- Trial name
- IBS (NCT05149599)
- Testing
- Saccharomyces cerevisiae
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Ziauddin University
Loss of Residual Renal Function, Technique Failure in Peritoneal Dialysis
Peritonitis and Loss of Residual Renal Function, Technique Failure and Mortality in Peritoneal Dialysis Patients
The primary objective is to analyze peritonitis rate and peritonitis bacteriology as risk factors for loss of residual renal function, technique failure and mortality in chronic kidney disease patients.
- Trial name
- NCT01977716
- Where
- Mexico
- Volunteers
- 350 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Chronic Idiopathic Constipation, Irritable Bowel Syndrome (IBS-C)
"Efficacy and Safety of Linaclotide in Chronic Constipation"
Goal of this study is to evaluate the efficacy and safety of two different doses of Linaclotide in improving bowel function and patient-reported outcomes among Bangladeshi patients with chronic constipation for 8 weeks along with…
- Conditions
- Chronic Idiopathic Constipation, Irritable Bowel Syndrome (IBS-C), Chronic Constipation, CIC
- Trial name
- LIN-CC-BD (NCT07431957)
- Testing
- Linaclotide 72 micrograms, Linaclotide 145 micrograms
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Md Mehedi Shahriar
Inflammatory Bowel Diseases
Validation Study for Disability Assessment Functional of Patients With Inflammatory Diseases Intestinal Chronic (VALIDate)
Inflammatory Bowel Diseases (IBD) often affect psychological, family, social and professional dimensions of patients' life, leading to disability which is essential to quantify as part of Patient-Reported Outcomes (PROs) newly…
- Trial name
- VALIDate (NCT03590639)
- Where
- 3 sites in France
- Volunteers
- 400 people
- Sponsor
- Nantes University Hospital
Functional Dyspepsia, Gastro Esophageal Reflux
Japanese Upper GI Symptoms Compared With Iranian and Canadian Patients Presenting
The purpose of this prospective cohort study is to compare upper GI symptoms and endoscopy findings in Canada with Japan and Iran, and correlate this with the upper GI microbiome.
- Conditions
- Functional Dyspepsia, Gastro Esophageal Reflux, Peptic Ulcer, Normal Control
- Trial name
- NCT03868267
- Where
- 3 sites in Canada, Iran and 1 more
- Volunteers
- 1,500 people
- Sponsor
- Hamilton Health Sciences Corporation
Rectal Cancer
Effect of a Post-operative Protocol of Early Mobilization on Functional Recovery and Postoperative Complications After Immediate Internal Pudendal Artery Perforator Flap Reconstruction for Irradiated Abdominoperineal Resection Defects: a Prospective, Randomized and Controlled Clinical Study.
Major abdominal oncology surgery is associated with substantial postoperative loss of functional capacity, and exercise may be an effective intervention to improve outcomes.
- Trial name
- NCT04795609
- Testing
- Early mobilization strategy adapted after immediate internal pudendal artery perforator flap reconstruction for abdominoperineal resection (intervention group).
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Anterior Resection Syndrome, Bowel Dysfunction
Studies in Patients With Low Anterior Resection Syndrome (LARS)
Colorectal Cancer is the commonest cancer diagnosed for both genders combined in Hong Kong. In 2015 16.6% of all new cancer cases registered on the Hong Kong registry were cancer of colon and rectum.
- Trial name
- NCT03885999
- Testing
- Fecobionics
- Where
- Hong Kong
- Volunteers
- 12 people
- Sponsor
- Giome
Bowel Dysfunction, Postoperative Complications
Sugammadex To IMprove Bowel Function
Colon and rectal surgery is associated with high cost, long length of stay, high postoperative surgical site infection rate, high incidence of postoperative nausea and vomiting, and a high rate of hospital readmission.
- Conditions
- Bowel Dysfunction, Postoperative Complications, Neuromuscular Blockade
- Trial name
- STIM_Bowel (NCT04546672)
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Oregon Health and Science University
Functional Gastrointestinal Disorders
Low FODMAP Diet in FD (PDS)
The goal of this dietary intervention study is to assess the efficacy and mechanisms of a low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet in functional dyspepsia patients.
- Trial name
- FFDU (NCT05832528)
- Testing
- Low-FODMAP diet
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Irritable Bowel Syndrome
Personalized Lifestyle Program in Treatment Resistant Irritable Bowel Syndrome
Patients with treatment resistant irritable bowel syndrome (IBS) are recruited from secondary care gastroenterology clinics in Stockholm and screened for eligibility criteria.
- Trial name
- NCT05028036
- Testing
- Personalized lifestyle treatment program
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
Functional Gastrointestinal Disorders, Dyspepsia
Stigma and Efficacy of Zhizhu Kuanzhong Capsules
Antidepressants are effective in patients with functional dyspepsia (FD), however, the stigma related with FD and antidepressants could affect treatment adherence and efficacy.
- Conditions
- Functional Gastrointestinal Disorders, Dyspepsia, Psychosomatic Disorder
- Trial name
- NCT05107999
- Testing
- Zhizhu Kuanzhong capsules (ZZKZ), Doxepin Hydrochloride (Doxepin)
- Where
- China
- Volunteers
- 76 people
- Sponsor
- RenJi Hospital
Fecal Incontinence
Transcutaneous Posterior Nerve Stimulation inTreatment of Fecal Incontience
Shafik and colleagues were the first to report the use of posterior tibial nerve stimulation (PTNS) for FI, and they documented improved continence after 4 weeks course.
- Trial name
- NCT04478799
- Testing
- Transcutanous Posterior Tibial Nerve Stimulation
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Batterjee Medical College
Irritable Bowel Syndrome, Microbial Colonization
The Effectiveness of Temple Stay in Irritable Bowel Syndrome
This research is a clinical trial aimed at improving the gut microbiome of patients with Irritable Bowel Syndrome (IBS) through a temple stay experience.
- Trial name
- NCT05999500
- Testing
- Temple stay experience
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- DongGuk University
Urinary Bladder, Neurogenic, Blood Pressure
Recovery of Bladder and Sexual Function After Human Spinal Cord Injury
This study will incorporate critical cross viscero-visceral intersystem interactions to investigate in a controlled laboratory setting the extent, severity, and frequency of occurrence of autonomic dysreflexia with respect to…
- Conditions
- Urinary Bladder, Neurogenic, Blood Pressure, Autonomic Dysreflexia, Bowel Incontinence
- Trial name
- NCT04193709
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Louisville
Irritable Bowel Syndrome
The Efficacy of Tradition Chinese Medicine in Patients With Irritable Bowel Syndrome
To test the efficacy of Traditional Chinese Medicine in relieving symptoms and change of quality of life of patients with Irritable Bowel Syndrome.
- Trial name
- TCM-IBS (NCT00676975)
- Testing
- Traditional Chinese Medicine
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Irritable Bowel Syndrome
Gluten-free Diet in Irritable Bowel Syndrome
To evaluate the effects of a gluten-free diet in irritable bowel syndrome.
- Trial name
- NCT02528929
- Testing
- Gluten-free diet
- Volunteers
- 48 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Non-alcoholic Fatty Liver Disease
Helicobacter Pylori Eradication in Subjects With Non-alcoholic Fatty Liver Disease
The aim of study was to evaluate the effect of helicobacter pylori eradication on liver function tests, lipid profile, homeostasis model assessment-IR (HOMA-IR) index, and anthropometric measurements (body mass index and waist…
- Trial name
- NCT01759628
- Testing
- H.pylori eradication
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Tehran University of Medical Sciences
Functional Dyspepsia, Gastroparesis
Brain-Gut Yoga for Functional Dyspepsia and Gastroparesis (FD-GP)
The purpose of this research study is to assess whether using a yoga-based intervention in practice is feasible (possible) and acceptable to patients with Functional Dyspepsia and/or Gastroparesis (FD-GP).
- Trial name
- FD-GP (NCT06732453)
- Testing
- Seated Yoga Skills Training in Functional Dyspepsia and Gastroparesis (FD-GP)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences