Clinical trials: Gastrointestinal Health
Crohn Disease
Can Intermittent Fasting Induce Weight Loss and Improve Gut Health as Compared to Standard Medical Care in Patients With Obesity/High BMI and Crohn's Disease.
Diet is a determinant of gut microbial diversity and composition and is recognized as a potential environmental trigger for IBD; for example, high-fat diets are associated with increased risk of CD in pre-clinical models, with…
- Trial name
- CD-Fast (NCT05230160)
- Testing
- Intermittent Fasting
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Calgary
Breast Carcinoma, Cervical Carcinoma
CATCH-UP Intervention in Increasing Cancer Screening and Prevention Care in Uninsured Patients at Community Health Centers
This randomized research trial studies the Community-based Health Information Technology (HIT) Tools for Cancer Screening and Health Insurance Promotion (CATCH-UP) intervention in increasing cancer screening and prevention care…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma, Health Status Unknown
- Trial name
- NCT02355262
- Testing
- Informational Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Cancer, Healthy
Collection and Distribution of Biospecimens for Novel Research Uses
iSpecimen aims to create a clinical partner network of hospitals, laboratories, academic institutions, and other healthcare organizations ("institutions") capable of providing researchers and educators ("researchers") with…
- Conditions
- Cancer, Healthy, Gastrointestinal Complication, Autoimmune Diseases
- Trial name
- NCT03848962
- Where
- 2 sites in United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- iSpecimen Inc
Side Effects of Creatine Monohydrate Dosing
Gastrointestinal and Fluid Retention Symptoms Associated With Creatine Monohydrate With and Without Loading Dose Over 28 Days of Supplementation
This study aimed to investigate the incidence and severity of GI symptoms associated with daily CM supplementation, with and without a loading phase, in healthy male and female adults.
- Trial name
- NCT07176325
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vireo Systems, Inc.
Constipation, Diarrhea
Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population
The purpose of this study is to investigate the effect of a daily supplement consisting of the probiotic bacteria, Lactobacillus reuteri, on the digestive health among persons 65 years and older.
- Conditions
- Constipation, Diarrhea, Indigestion, Reflux
- Trial name
- NCT01837940
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- Sweden
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Gastrointestinal Discomfort, Bloating
Multi-strain Probiotic Supplement for Digestive Comfort and Well-being in Healthy Women
This study looks at whether a daily probiotic supplement can help improve mild-to-moderate stomach and digestive symptoms, such as gas and bloating, in women who also experience symptoms commonly associated with hormonal…
- Trial name
- NCT07831317
- Testing
- Active: Multi-strain probiotic dietary supplement
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Daily Nouri
Human Papilloma Virus, Cervical Cancer
Integrating a Health Information Technology System for Primary and Secondary Cervical Cancer Prevention
The project aims to increase HPV vaccination and cervical cancer screening through a web-based mobile health education program called, Wheel of Wellness (WoW) and a brief negotiated interview (BNI).
- Conditions
- Human Papilloma Virus, Cervical Cancer, Human Papillomavirus Infection, Oropharyngeal Cancer
- Trial name
- NCT03346915
- Testing
- WoW and BNI
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Functional Gastrointestinal Disorders, Patient Compliance
SMS Reminders and Treatment Compliance and Efficacy in Patients With FGIDs
The effect of SMS follow-up on drug compliance and efficacy in patients with FGIDs has not been reported in the literature. We, therefore, conducted a prospective randomized controlled trial to investigate whether SMS follow-up…
- Trial name
- NCT04052750
- Testing
- SMS follow-up
- Where
- China
- Volunteers
- 176 people
- Sponsor
- RenJi Hospital
Non-Alcoholic Fatty Liver Disease
BeijngFH Health Cohort Study
Metabolic associated fatty liver disease(MEFLD) is a major chronic liver disease that can lead to various adverse events, such as liver cancer, cardiovascular disease, and chronic kidney disease.
- Trial name
- FHCS (NCT05546086)
- Where
- China
- Volunteers
- 8,103 people
- Sponsor
- Beijing Friendship Hospital
Cancer of the Colon
Colorectal Cancer Screening in a Community Health Setting
This randomized controlled pilot study at the Health Annex, Family Practice \& Counseling Network (FPCN), a community clinic in Southwest Philadelphia, aimed at providing data on the feasibility of a mailed FIT approach to CRC…
- Trial name
- NCT03072095
- Testing
- Text-only, Text + Lottery
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Gut Health
A Study to Evaluate the Effects of a Butyrate-Polyphenol Formulation on Gut Health and Associated Symptoms
The purpose of the study is to evaluate the efficacy of a butyrate/polyphenol formulation on modulation of the gut microbiome and gastrointestinal symptoms using questionnaires in individuals with self-reported gastrointestinal…
- Trial name
- NCT07371975
- Testing
- Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Attention Impaired, Mental Health Issue
Brief Mental Training and Internal Attentional Control
Previous research documented that real-time feedback on attention as well as related forms of mental training (e.g. mindfulness meditation) may be used to train and impact external attentional control.
- Conditions
- Attention Impaired, Mental Health Issue, Rumination
- Trial name
- NCT05353231
- Testing
- Attention Feedback Awareness and Control Training (A-FACT), Mindful Disengagement from Thoughts Training (MDTT)
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Colorectal Cancer (Diagnosis), Anal Cancer
Mind-Body Sexual Well-Being Program for Female GI Cancer Survivors
This record describes two distinct study phases: 1) A small open pilot trial including up to 10 participants, intended to generate descriptive feedback on regarding perceived benefits and areas for improvement for a group-based…
- Conditions
- Colorectal Cancer (Diagnosis), Anal Cancer, Sexual Dysfunction Female
- Trial name
- NCT07795801
- Testing
- Mind-Body Group Intervention, Enhanced Usual Care Control (EUCC)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus, Obesity
Early Tracking of Childhood Health Determinants (ETCHED) Study
Background: Children s weight has increased sharply in recent years. This may put them at higher risk for health problems. High blood glucose in a pregnant mother and too much weight gain during pregnancy also may have long-term…
- Conditions
- Diabetes Mellitus, Obesity, Fatty Liver
- Trial name
- NCT03481829
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Pancreas Disease
Baby Formula and Health
The purpose of this study is to learn about how different types of carbohydrates used in infant formula may affect a baby's intestines and pancreas.
- Trial name
- NCT04559490
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Inflammatory Bowel Diseases, Periodontitis
Oral Health-related Quality of Life (OHRQoL) in Patients With Inflammatory Bowel Disease (IBD)
IBD patients have a higher risk of oral diseases that affect the oral mucosa, the teeth and the tooth supporting tissues. These conditions are often associated with pain, bleeding and impaired masticatory function which may have…
- Conditions
- Inflammatory Bowel Diseases, Periodontitis, Dental Caries, Tooth Loss
- Trial name
- OQal-MICI (NCT05096897)
- Testing
- Self-administrated questionnaires
- Where
- France
- Volunteers
- 138 people
- Sponsor
- University Hospital, Lille
Time Restricted Feeding, Exercise
Time-Restricted Eating, Exercise and Cardiometabolic Health in Obesity
In Spain, overweight and obesity prevalence is reaching 70% in men and 50% in women. Excess of triglycerides are usually stored in the subcutaneous adipose tissue (SAT), until a point where SAT is unable to expand further.
- Conditions
- Time Restricted Feeding, Exercise, Hepatic Steatosis, Cardiometabolic Syndrome
- Trial name
- TEMPUS (NCT05897073)
- Testing
- Time-restricted eating intervention, Exercise intervention, Time-restricted eating plus exercise intervention
- Where
- 2 sites in Spain
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
IBS - Irritable Bowel Syndrome
Assessment of Psychological Symptoms and Health Related Quality of Life in Patients With Irritable Bowel Syndrome
To evaluate the relation between the clinical presentations and the psychiatric co-morbidities with the quality of life in patients with irritable bowel syndrome.
- Trial name
- NCT05480059
- Testing
- A questionnaire
- Volunteers
- 80 people
- Sponsor
- Assiut University
Quality of Life, Ulcerative Colitis
Association Between Self-reported Web-based SCCAI and Health-related Quality of Life Index in UC Patients
An accurate assessment of disease activity is crucial for the treatment of patients with ulcerative colitis (UC). Recent studies have reported that the Simple Clinical Colitis Activity Index (SCCAI) correlates well with Mayo…
- Trial name
- UC (NCT04197973)
- Where
- South Korea
- Volunteers
- 225 people
- Sponsor
- YooJin Lee