Clinical trials: Gastrointestinal Polypectomy
Pain, Anesthesia
Effect of Low-dose Esketamine Combined With Target-controlled Infusion of Propofol for Painless Gastrointestinal Endoscopy
Purpose: 1. To determine the efficacy of low-dose esketamine in painless gastrointestinal endoscopy. 2. To determine the safety of low-dose esketamine in painless gastrointestinal endoscopy. 3.
- Trial name
- NCT04691076
- Testing
- Propofol, Esketamine, Fentanyl
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tianjin Union Medical Center
Malignant Colorectal Polyp, Colorectal Cancer
Malignant Polyp Registry
The purpose of this study is to learn more about malignant colorectal polyps (early colorectal cancers removed during colonoscopy) and the risk that cancer remains, comes back, or spreads after the polyp is removed.
- Conditions
- Malignant Colorectal Polyp, Colorectal Cancer, T1 Colorectal Cancer
- Trial name
- NCT07619079
- Testing
- Questionnaires
- Where
- 7 sites in United States
- Volunteers
- 500 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Post Polypectomy Bleeding in Anticoagulated Patients, Gastrointestinal Hemorrhage
Hemorrhage Following Small Polyp Resection in the Colon in Anticoagulated Patients
One of the well-known of complications post colonic polypectomy is bleeding usually occuring in the 2-week period following the procedure. Patients treated with oral anticoagulation (e.g.
- Trial name
- NCT02375646
- Testing
- Warfarin, LMW Heparin
- Volunteers
- 286 people
- Sponsor
- Hadassah Medical Organization
Familial Adenomatous Polyposis
Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis
The purpose of this study is to collect prospective observational data regarding patients with diagnosed Familial Adenomatous Polyposis (FAP) undergoing cold snare polypectomy for duodenal adenomas
- Trial name
- COPDA (NCT03471403)
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- Western Sydney Local Health District
Colorectal Cancer
Prospective Randomized Comparison of Cold Snare Polypectomy and Conventional Polypectomy
The aim of this study is to compare cold snare polypectomy and conventional polypectomy for the removal and retrieval of small colorectal polyps.
- Trial name
- COLD (NCT00763425)
- Testing
- cold polypectomy, conventional polypectomy
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Showa Inan General Hospital
Colorectal Cancer
Dietary Bioflavonoid Supplementation for the Prevention of Neoplasia Recurrence
Prove the hypothesis that dietary supplementation with bioflavonoids will diminish the recurrence rate of colonic neoplasia, we will implement a clinical trial comparing bioflavonoids and placebo in a double blind randomized…
- Trial name
- NCT00609310
- Testing
- Flavonoids
- Where
- Germany
- Volunteers
- 382 people
- Sponsor
- Technische Universität Dresden
Colorectal Neoplasms
Study of Narrow Band Imaging in the Characterization of Residual Neoplasia After Endoscopic Piecemeal Mucosal Resection
This study is designed to evaluate the diagnostic accuracy of Narrow Band Imaging (NBI) compared with High Definition White Light colonoscopy (WLE) for detection of residual neoplasia in subjects with piecemeal polypectomy scars.
- Trial name
- CROMOPIE (NCT02448693)
- Testing
- WLE, NBI
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Parc de Salut Mar
Colorectal Cancer, Colonoscopy
ColoReg: A Register for Gastrointestinal Endoscopy Reports and Examination Videos
With the participants help, the investigators aim to track treatment methods, treatment outcomes, and adverse events, as well as document the treatment strategies used during endoscopic colorectal cancer prevention and treatment.
- Conditions
- Colorectal Cancer, Colonoscopy, Polypectomy
- Trial name
- NCT06920680
- Where
- 2 sites in Germany
- Volunteers
- 1,834 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Colorectal Neoplasms
Fecal Immunochemical Test for Post-polypectomy Surveillance to Reduce Unnecessary eNdoscopy
This is an observational study in a clinical setting to estimate the prevalence of advanced colorectal neoplasia (ACN) at colonoscopy in those with a history of low or high risk polyps or a family history of CRC/polyps and to…
- Trial name
- FIT2RUN (NCT05396560)
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- University of Calgary
Adenoma Colon, Colon Adenoma
Conventional Endoscopic Mucosal Resection Versus Cold Snare Endoscopic Mucosal Resection of Colonic Lateral Spreading Lesions - A Randomised Controlled Trial
Comparing the complete resection rate and subsequent adenoma recurrence rate at surveillance colonoscopy of 15-40mm laterally spreading adenomas for conventional EMR vs. cold snare EMR.
- Conditions
- Adenoma Colon, Colon Adenoma, Colon Cancer
- Trial name
- NCT04138030
- Testing
- Conventional Endoscopic Mucosal Resection, Cold Snare Endoscopic Mucosal Resection
- Where
- Australia
- Volunteers
- 182 people
- Sponsor
- Western Sydney Local Health District
Bowel Cancer
Randomised Comparison of 2 Cold Snare Polypectomy Techniques
Different modalities are employed to remove small colonic polyps which potentially harbour a cancer risk. But, they can all vary in their completeness of removal, safety and the histological quality and the gold standard…
- Trial name
- NCT02208401
- Testing
- conventional cold snare polypectomy, Cold snare polypectomy with suction
- Where
- United Kingdom
- Volunteers
- 112 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Colorectal Polyps
Colorectal Polypectomy Upon Insertion And Withdrawal Or Upon Withdrawal Only?
The investigators aim to assess the procedure time and miss rate of polyps when performing polypectomy in the colon on the way up* and down or only on the way down.
- Trial name
- NCT01607827
- Testing
- Polyp removal upon insertion and withdrawal, Polyp removal upon withdrawal only
- Where
- Switzerland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Colorectal Adenoma, Colorectal Polyp
Validation of the Global Polypectomy Assessment Tool (GPAT)
Colorectal polypectomy is offten incompletely performed with high variability between endoscopists, resulting in interval cancer or repeated procedures.
- Conditions
- Colorectal Adenoma, Colorectal Polyp, Colo-rectal Cancer
- Trial name
- GPAT (NCT05877456)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Colonic Polyps, Colorectal Neoplasms
Comparative Effectiveness of Hot Versus Cold Snare Polypectomy of Small Colorectal Polyps
This study aims to investigate the comparative effectiveness between polyp removal with or without electrical current. The investigators want to include 600 polyps in the trial.
- Conditions
- Colonic Polyps, Colorectal Neoplasms, Adenoma
- Trial name
- HOT/COLD (NCT02484079)
- Testing
- Polypectomy
- Volunteers
- 429 people
- Sponsor
- Sorlandet Hospital HF
Polyp of Colon, Gastrointestinal Bleeding
Polypectomy With Hot vs Cold Snare in Small Colonic Lesions
Colonoscopy is the technique of choice for the diagnosis and prevention of colorectal cancer (CRC). The identification and extirpation of adenomas decreases the incidence of CRC by up to 76%.
- Conditions
- Polyp of Colon, Gastrointestinal Bleeding, Colonic Adenoma
- Trial name
- Polypech-c (NCT03783156)
- Testing
- hot snare, cold snare
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital del Rio Hortega
Liver Cirrhosis, Portal Hypertension Related to Cirrhosis
Colonic Polypectomy in Cirrhotic Patients With Portal Hypertension
The goal of this retrospective cohort study is to evaluate the risk of post-polypectomy bleeding following the colonoscopy resection of lower gastrointestinal polyps in patients with liver cirrhosis with portal hypertension.
- Conditions
- Liver Cirrhosis, Portal Hypertension Related to Cirrhosis, Polyp of Colon, Polypectomy
- Trial name
- NCT06832826
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Large Polyps in the Gastrointestinal Tract
Evaluation of Blood as a Submucosal Cushion During Endoscopic Polypectomy and Mucosal Resection
For removal of large flat lesions of the gastro-intestinal tract injection of a solution under the lesion creates a "safety" cushion and protects from damage to the gastrointestinal tract wall.
- Trial name
- NCT00583466
- Testing
- Autologous blood injection, Normal saline, HPMC
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University