Clinical trials: Gastrointestinal Problems
Deglutition Disorders, Nutritional Deficiency
Coverage of Requirements After Consumption of a Nutritional Formula in Patients With Chewing/Swallowing Problems.
Effect of a nutritional formula on the nutritional requirements in patients with chewing/swallowing problems during one month
- Conditions
- Deglutition Disorders, Nutritional Deficiency, Chew Problems, Swallowing Disorder
- Trial name
- VEGENAT MED (NCT03727191)
- Testing
- Control Group (education, guidelines, recommendations), Experimental Group (education, guidelines, 2 pckts diet, recommendations)
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Anemia, Necrotizing Enterocolitis
RBC Irradiation, Anemia and Gut Injury
The purpose of this trial is to study the effect that anemia and red blood cell (RBC) transfusions have on oxygen levels in the digestive tracts of extremely low birth weight (ELBW) infants and to look for possible markers in a…
- Trial name
- RBC-mNIRS (NCT02741648)
- Testing
- Near Infrared Spectroscopy, Non-invasive Image-based Anemia Assessment
- Where
- 3 sites in United States
- Volunteers
- 324 people
- Sponsor
- Emory University
Alpha1-Antitrypsin Deficiency
A Study in Adults to Learn About Inherited Alpha-1 Antitrypsin Deficiency (AATD) and AATD Related Liver Problems
The liver produces a protein called alpha-1 antitrypsin (AAT). AAT is normally released into the bloodstream. In some people, the liver makes an abnormal version of AAT, called Z-AAT.
- Trial name
- ALPHATUDE (NCT06512454)
- Testing
- No Intervention
- Where
- 8 sites in United States, Austria and 4 more
- Volunteers
- 500 people
- Sponsor
- Takeda
Chronic Liver Disease (CLD), Liver Cirrhosis
Heart Problems in Children With Chronic Liver Disease
Chronic liver disease (CLD) in children can sometimes lead to complications in other parts of the body, including the heart. The primary purpose of this observational study is to assess the presence and type of cardiac problems…
- Conditions
- Chronic Liver Disease (CLD), Liver Cirrhosis, Cardiac Abnormalities, Portopulmonary Hypertension
- Trial name
- NCT07502196
- Volunteers
- 60 people
- Sponsor
- Assiut University
Depression, Anxiety
Effects of an Integrative Treatment Model to Reduce Anxiety and Depression in Minor Mental Health Problems and Medically Unexplained Symptoms
Minor mental health problems, MMHP, like mild depression and anxiety, and medically unexplained symptoms, MUS, symptoms with no known underlying organic disease, are strongly associated to each other.
- Conditions
- Depression, Anxiety, Irritable Bowel Syndrome, Fibromyalgia
- Trial name
- NCT01631500
- Testing
- Conventional treatment, Integrative treatment, Therapeutic acupuncture
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Göteborg University
Pancreas Transplantation, Kidney Transplantation
Gastrointestinal and Health-related Quality of Life Outcomes in Patients With Simultaneous Pancreas-Kidney Transplants
Treatment with the immunosuppressive drug mycophenolate mofetil (MMF) may result in gastrointestinal (GI) complications in some patients.
- Trial name
- NCT00267150
- Testing
- Enteric-coated mycophenolate sodium (EC-MPS)
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Novartis Pharmaceuticals
Dysphagia
Yale Swallow Protocol in Extubated Patients
The purpose of this study is to determine if the Yale Swallow Protocol is an effective screen for aspiration in recently extubated patients.
- Trial name
- NCT03352908
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- University of Wisconsin, Madison
Fecal Incontinence, Childbirth Problems
Prevalence of Anal Sphincter Defects After Childbirth
The incidence of obstetric sphincter tears has risen to 15-30% and the prevalence of anal incontinence (AI) symptoms after childbirth may be as high as 40%.
- Trial name
- PRADA (NCT05196620)
- Testing
- Endoanal Ultrasound (EAUS)
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad de Zaragoza
Intravenous Drug Abuse, HIV Infections
Reducing Health Problems Associated With Injection Drug Use
The purpose of this study is to develop and test an intervention to reduce bacterial and viral infections among injection drug users.
- Trial name
- NCT01128920
- Testing
- Skin and Needle Hygiene Intervention, No intervention - assessment-only condition
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Northern Colorado
Dysphagia, Parkinson Disease
A Digital Therapeutic Platform for Swallowing and Drooling Problems in Parkinson's
The purpose of this study is the development and early-stage validation of a wearable sensor for dysphagia in patients with PD.
- Trial name
- NCT04664634
- Testing
- Aria Sensor
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Northwestern University
Niemann-Pick Disease, Type C
Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease
Due to different study designs, the sponsor separated Part C into this separate registration (NCT04958642), leaving Parts A/B in NCT02534844.
- Trial name
- NCT04958642
- Testing
- Adrabetadex
- Where
- 30 sites in United States, Australia and 7 more
- Volunteers
- 66 people
- Sponsor
- Mandos LLC
Gastrointestinal Diseases
Prospective Evaluation of the Clinical Utility of Endoscopically Placed Self-expandable Stents
The investigators' believe that it is important to medical practice to obtain information on how expandable metal stents work in a large group of patients who have metal stents placed in the gastrointestinal system.
- Trial name
- NCT00968552
- Testing
- Self-expandable stent placement via endoscopy
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Florida
Hepatic Insufficiency, Hepatic Impairment
A Clinical Study of Enlicitide Decanoate in People With Liver Function Problems (MK-0616-030)
Researchers have designed a new study medicine called enlicitide decanoate as a new way to lower the amount of low-density lipoprotein cholesterol (LDL-C) in a person's blood.
- Trial name
- NCT06575959
- Testing
- Enlicitide
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Inflammatory Bowel Diseases, Mental Health Issue
IBDminds - Mapping the Influence of aNxiety and DepreSsion on IBD
People with Inflammatory bowel disease (IBD) can get challenging symptoms. Things like diarrhoea, tummy pain and being tired all the time are common. People often get IBD in their teens or twenties.
- Trial name
- IBDminds (NCT07175454)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 450 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Healthy, Liver Diseases
A Study to Test How Avenciguat (BI 685509) is Taken up in the Body of People With and Without Liver Problems
This study is open to people with and without severe liver problems. People can join the study if they are 18 to 80 years of age and have a body mass index (BMI) between 18.5 and 42 kg/m2.
- Trial name
- NCT06272058
- Testing
- Avenciguat (BI 685509)
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Autism Spectrum Disorder, Gastrointestinal Diseases
Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.
This study aims to evaluate the efficacy of fecal microbiota transplantation on the gastrointestinal symptoms, autistic symptoms and emotional behavior symptoms of patients with autism spectrum disorder, and investigate the…
- Conditions
- Autism Spectrum Disorder, Gastrointestinal Diseases, Healthy
- Trial name
- NCT06290258
- Testing
- Fecal microbiota transplantation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Functional Voice and Swallowing Outcomes
Swallowing and Voice Outcomes After Thyroidectomy
Impairment in voice and swallowing functions are common after thyroidectomy. The investigators aimed to evaluate the objective functional voice and swallowing outcomes in a series of patients undergoing thyroidectomy.
- Trial name
- NCT03436186
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ege University
Depressive Symptoms, Anxiety Symptoms
Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants
The aim of this randomized controlled trial (RCT) is to investigate the effectiveness of a culturally adapted internet-based cognitive behavioral therapy (i-CBT) intervention in reducing symptoms of common mental health issues…
- Conditions
- Depressive Symptoms, Anxiety Symptoms, Grief, Psychological Trauma
- Trial name
- i-CBT (NCT06828276)
- Testing
- Culturally adapted i-CBT
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Karolinska Institutet
Dysphagia
The Effect of Food Taste, Temperature, and Viscosity on Swallowing Efficiency
The purpose of this study is to evaluate the effect of taste on swallowing efficiency, to evaluate the effect of temperature on swallowing efficiency, and to evaluate the effect of viscosity on swallowing efficiency.
- Trial name
- NCT01270204
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Musculoskeletal Problem, Respiratory Problem
Effectiveness of Western Medicine Outpatient Consultations in Primary Care
Background: Primary care plays an important role in health care delivery, but there is little research on its effectiveness. Western medicine is the most widely used and Traditional Chinese medicine (TCM) is gaining popularity.
- Conditions
- Musculoskeletal Problem, Respiratory Problem, Gastrointestinal Problem, All Primary Care Problem
- Trial name
- NCT00887133
- Where
- China
- Volunteers
- 1,469 people
- Sponsor
- The University of Hong Kong