Clinical trials: Gastrointestinal Surgery
Inflammatory Bowel Diseases, Quality of Life
Delayed Surgery in Inflammatory Bowel Disease
The timing of elective surgery in inflammatory bowel disease (IBD) may be crucial according to progression of the disease. In most cases, medical treatment has failed when surgery is discussed.
- Conditions
- Inflammatory Bowel Diseases, Quality of Life, Surgery
- Trial name
- NCT05810155
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Rectal Cancer, Organ-Space Surgical Site Infection
Organ/Space Surgical Site Infection and Recurrence and Survival in Rectal Cancer Surgery
In rectal cancer surgery, the organ/space surgical site infection (O/S-SSI) has an impact on patient's prognosis. Its influence in the oncologic outcomes remains controversial.
- Trial name
- VINCat_PDO_2 (NCT06382415)
- Where
- Spain
- Volunteers
- 3,826 people
- Sponsor
- Hospital de Granollers
Perforated Peptic Ulcer, Fast Track Surgery
Impact of Abdominal Drains on the ERAS Pathway in Peptic Perforation
This study plans to assess the effect of placement of abdominal drains on the outcomes of ERAS (Enhanced recovery after surgery) protocol in the perioperative management of peptic perforation.
- Conditions
- Perforated Peptic Ulcer, Fast Track Surgery, Perforated Bowel, Post-Op Complication
- Trial name
- TUBELESS (NCT05368233)
- Testing
- ERAS protocol
- Where
- India
- Volunteers
- 92 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Pancreatic Cancer, Liver Metastases
CE-IOUS for Patients With Pancreatic Cancer Undergoing Surgery: A Prospective, Proof-of-concept Trial
BACKGROUND: Pancreatic Cancer (PC) is one of the leading cancer-related causes of death worldwide, with the majority of patients undergoing potentially curative surgery.
- Trial name
- NCT04683497
- Testing
- Contrast-enhanced Intraoperative Ultrasound
- Volunteers
- 50 people
- Sponsor
- University of Thessaly
Biliary Tract Diseases
Cholecystitis in Villavicencio Hospitals
Background: Acute cholecystitis is a frequent cause of visits to the emergency ward. The complications of delays in attention and surgical therapy are substantial and should be considered to prevent them timely.
- Trial name
- NCT06048575
- Testing
- Cholecystectomy
- Where
- Colombia
- Volunteers
- 609 people
- Sponsor
- Hospital Departamental de Villavicencio
Lymph Leakage, Chyle Into Mesentery; Extravasation
Prevention of Chyle-leak After Major Pancreatic Surgery
Chyle is lymphatic fluid present in the wall of the intestine. It flows trough lymphatic vessels to cisterna chyli and to venous circulation carrying lymphatic fluid, long-chain triglyceride fatty acids and proteins, fatty…
- Conditions
- Lymph Leakage, Chyle Into Mesentery; Extravasation, Pancreatic Cancer, Complication of Surgical Procedure
- Trial name
- NCT03167814
- Testing
- Diet group
- Where
- Finland
- Volunteers
- 96 people
- Sponsor
- Helsinki University Central Hospital
Liver Cancer, Ablation Techniques
The Safety and Efficacy of Irreversible Electroporation for the Treatment of Perivascular Liver Cancers
Malignant liver tumors are among the most common cancers worldwide, with over 10,000 new cases reported annually in Taiwan. Despite the availability of various treatment options, the prognosis for primary hepatocellular carcinoma…
- Conditions
- Liver Cancer, Ablation Techniques, Radiology
- Trial name
- NCT07214363
- Testing
- Irreversible Electroporation Ablation Generator
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Postoperative Complications, Cardiovascular Diseases
Comparing Traditional Risk Scores and an AI-Based Multimodal Model for Predicting Cardiovascular Events After Gastrointestinal Surgery
The goal of this observational study is to develop and evaluate an artificial intelligence (AI)-based multimodal model for predicting major cardiovascular events within 30 days after gastrointestinal surgery in adults at Bach Mai…
- Conditions
- Postoperative Complications, Cardiovascular Diseases, Digestive System Surgical Procedures
- Trial name
- GI-MACE-AI (NCT07539532)
- Where
- Vietnam
- Volunteers
- 5,000 people
- Sponsor
- Bach Mai Hospital
Esophageal Cancer, Gastric Cancer
Prospective Analysis of Robot-Assisted Surgery
The robot-assisted surgery allows three-dimensional view, detailed access of small structures, depth perception and articulated movements with wide latitude.
- Conditions
- Esophageal Cancer, Gastric Cancer, Pancreatic Cancer, Rectal Cancer
- Trial name
- NCT02292914
- Testing
- Robot-assisted surgery, Conventional Surgery
- Where
- Brazil
- Volunteers
- 1,120 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Adenocarcinoma, Stomach Neoplasm
Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer
The goal of this clinical trial is to evaluate the efficacy and safety of radiotherapy combined with chemotherapy and anti-PD-1 immunotherapy followed by surgery for the primary and metastatic lesions in patients with limited…
- Conditions
- Adenocarcinoma, Stomach Neoplasm, Gastroesophageal-junction Cancer, Oligometastatic Disease
- Trial name
- Miracle-G (NCT06121700)
- Testing
- Radiotherapy targeted to the primary lesion, Radiotherapy targeted to the metastatic lesions, Anti-PD-1 monoclonal antibody
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Fudan University
Peritoneal Carcinomatosis
Longitudinal Study of CRS/HIPEC for Peritoneal Carcinomatoses
Longitudinal Study of the Effect of Cytoreductive Surgery and HIPEC in Patients With Peritoneal Carcinomatoses
- Trial name
- CRS/HIPEC (NCT04108936)
- Where
- 2 sites in Germany
- Volunteers
- 250 people
- Sponsor
- University of Regensburg
GERD
Conventional Nissen Fundoplication Versus Laparoscopic Nissen Fundoplication
This is a long-term follow-up of a prospective randomized trial comparing open and laparoscopic Nissen fundoplication.
- Trial name
- NCT01230944
- Testing
- Laparoscopic Nissen fundoplication, Open Nissen fundoplication
- Where
- Finland
- Volunteers
- 110 people
- Sponsor
- Turku University Hospital
Morbid Obesity, Postoperative Pain
Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens
Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are…
- Conditions
- Morbid Obesity, Postoperative Pain, Postoperative Bowel Function, Postoperative Ambulation
- Trial name
- NCT01249872
- Testing
- GROUP A : 0 mg MORPHINE-0.1% LEVOBUPIVACAINE, GROUP B : 1 mg MORPHINE- 0.1% LEVOBUPIVACAINE, GROUP C : 2 mg MORPHINE-0.1% LEVOBUPIVACAINE
- Where
- Greece
- Volunteers
- 96 people
- Sponsor
- University of Patras
Anxiety, Gastric Carcinoma
Educational Brochure in Preparing Patients With Gastric Cancer and Their Caregivers for Recovery After Surgery
This pilot clinical trial studies an educational brochure in preparing patients with gastric cancer and their caregivers for recovery after surgery.
- Conditions
- Anxiety, Gastric Carcinoma, Stress
- Trial name
- NCT02334332
- Testing
- Educational Intervention, Standard Follow-Up Care, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Rectovaginal Fistula, Obstetric Complication
Musset's Surgical Technique: Evaluation of Long-term Results (LONGOMUSSET)
The surgical technique of Musset has shown its effectiveness for the cure of recto-vaginal fistulas. Recto-vaginal fistulas are mostly post-obstetric (88%).
- Trial name
- LONGOMUSSET (NCT05079139)
- Testing
- surgical technique of Musset
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Rectal Adenocarcinoma, Stage II Rectal Cancer AJCC v8
Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer
This pilot trial studies how well active surveillance and chemotherapy before surgery work in treating participants with stage II-III rectal cancer.
- Conditions
- Rectal Adenocarcinoma, Stage II Rectal Cancer AJCC v8, Stage IIA Rectal Cancer AJCC v8, Stage IIB Rectal Cancer AJCC v8
- Trial name
- NCT03594630
- Testing
- Chemotherapy, Patient Observation, Questionnaire Administration
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- M.D. Anderson Cancer Center
Colo-rectal Cancer
Psychological distREsS hipEc oR pelVic Exenteration
The purpose of this study is to describe type and extent of psychological distress (adverse effects) in patients undergoing surgery for colorectal cancer with peritoneal metastases and after surgery for colorectal cancer with…
- Trial name
- PRESERVE (NCT04956107)
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 225 people
- Sponsor
- University of Aarhus
Appendicitis Acute, Appendicitis Perforated
Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis
The exploratory objective of this pilot study is to evaluate the feasibility and safety of an enhanced recovery protocol that will allow adult patients to be discharged to home on an oral antibiotic regimen for three days…
- Conditions
- Appendicitis Acute, Appendicitis Perforated, Appendicitis With Perforation, Appendicitis Suppurative
- Trial name
- NCT06948071
- Testing
- Discharge on oral antibiotics
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Obesity, Morbid, Diabete Type 2
Indocyanine Green Test for Evaluation of Perfusion of Staple Line of the Stomach During Laparoscopic Sleeve Gastrectomy
The investigators present the case of a 40-year-old female underwent laparoscopic sleeve gastrectomy. Intraoperative indocyanine green test was performed
- Conditions
- Obesity, Morbid, Diabete Type 2, Cardiac Disease, Vascular Diseases
- Trial name
- NCT05337644
- Testing
- Indocyanine green solution
- Where
- Italy
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Rectal Prolapse, Procidentia
An International Double Cohort Study to Compare Laparoscopic Ventral Rectopexy With Laparoscopic Resection Rectopexy
Background: Rectal prolapse (RP) is the descent of the upper rectum and is a common problem in the western world. Surgery is the only definite treatment and is preferably performed minimally invasive.
- Trial name
- LaProS (NCT01595412)
- Testing
- Laparoscopic Resection Rectopexy, Laparoscopic Ventral Rectopexy
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic