Clinical trials: Gastrointestinal Symptoms
Short Bowel Syndrome (SBS)
Efficacy and Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome
The purpose of this study is to understand the safety and efficacy of twice weekly glepaglutide 10 mg in adult patients with short bowel syndrome (SBS), who were previously enrolled in the EASE SBS 2 or EASE SBS 3 trials.
- Trial name
- EASE SBS 6 (NCT07228403)
- Testing
- Glepaglutide 10 mg
- Where
- 16 sites in United States, Belgium and 5 more
- Volunteers
- 28 people
- Sponsor
- Zealand Pharma
Gastrointestinal Symptoms
Foot Reflexology and Acupressure on Gastrointestinal Symptoms
This research was planned to evaluate the effects of foot reflexology and acupressure applications on gastrointestinal symptoms in women going through menopause.
- Trial name
- Menopausal (NCT07528534)
- Testing
- Foot Reflexology, Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Osmaniye Korkut Ata University
Cognition, Muscle Strength
Dietary Supplements and Middle Aged Women (Creatine)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Muscle Strength, Fatigue Symptom, Blood Pressure and Augmentation Index
- Trial name
- NCT07729930
- Testing
- Creatine Monohydrate
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Standard Quadruple Antiemetic Therapy, Electroacupuncture
Electroacupuncture for Chemotherapy-Induced GI Symptom Clusters in Breast Cancer
This study aims to elucidate the therapeutic efficacy of electroacupuncture in managing chemotherapy-induced gastrointestinal symptom clusters through clinical research.
- Conditions
- Standard Quadruple Antiemetic Therapy, Electroacupuncture, Chemotherapy-induced Gastrointestinal Symptom Cluster
- Trial name
- NCT06952920
- Testing
- electroacupuncture, standard quadruple antiemetic therapy
- Where
- China
- Volunteers
- 388 people
- Sponsor
- Jiuda Zhao
GI Issues, Bowel Movements
The Effect of Humiome® Post LB on Gut COMFort in healthY Adult Volunteers
The goal of this double-blind, randomized placebo-controlled study is to evaluate the effect of an 8-week supplementation of Humiome ® Post LB (170 mg) on bowel movements in healthy adult volunteers compared to Placebo adjusted…
- Conditions
- GI Issues, Bowel Movements, Gastrointestinal Symptoms
- Trial name
- NCT06937814
- Testing
- Humiome ® Post LB
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Gastrointestinal, Mobile Health
GutCheck: Optimization of a Personalized Mobile Health App for Survivors of Gastrointestinal Cancer
There are two components to the study: a patient and a clinician study. The clinician study will include one-hour semi-structured interviews with oncology specialists to identify facilitators and barriers to integrating digital…
- Conditions
- Gastrointestinal, Mobile Health, Gastrointestinal Symptoms, Gut Health
- Trial name
- NCT07661017
- Testing
- Stool Sample, App Activity
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Obesity, Morbid, Bariatric Surgery
Evaluation of Metabolic Parameters, Intestinal Permeability and Gastrointestinal Symptoms After Bariatric Surgery in Body Weight Management
This study aims to evaluate the changes in metabolic parameters, intestinal permeability, and gastrointestinal symptoms in individuals who have undergone bariatric surgery (Laparoscopic Sleeve Gastrectomy - LSG) for obesity…
- Conditions
- Obesity, Morbid, Bariatric Surgery, Intestinal Permeability, Gastrointestinal Symptoms
- Trial name
- METABAR (NCT07643376)
- Testing
- Clinical and Biochemical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Toros University
Gastrointestinal Symptoms
Gastrointestinal Health Survey of Dalian College Students
This is a cross-sectional study aimed to investigate the current status of gastrointestinal health among full-time undergraduate students aged 18-25 years in Dalian, and to clarify the influences of factors such as diet, sleep…
- Trial name
- NCT07634887
- Testing
- Self-Administered Questionnaire Survey
- Volunteers
- 1,020 people
- Sponsor
- DiproBio (Shanghai) Co., Ltd.
Upper Gastrointestinal Symptoms
Comparative Study of MCCE With/Without Tether vs Conventional Upper Endoscopy in Patients With Upper Abdominal Symptoms
A prospective single blinded, tandem study, comparing a magnetically controlled capsule with or without a tether (MCC or MCC-T) with conventional upper endoscopy for the diagnosis of patients with upper abdominal symptoms.
- Trial name
- NCT04605302
- Testing
- MCC/MCC-T, Standard gastroscopy
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AnX Robotica Corp.
Gastrointestinal Symptoms
Impact of Dietary Fibre Supplementation on Gut Symptoms in Healthy Participants
Fibres found in food are mainly carbohydrates that are not broken down or absorbed during human digestion but instead pass to the colon to be fermented by microbes.
- Trial name
- KiVa (NCT07587424)
- Testing
- cellulose, Oat fibre, Rye fibre
- Where
- Finland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Gastrointestinal Microbiome (Focus), Gastrointestinal Symptoms
The Effect of a Synbiotic on Intestinal Barrier Function and Microbiota Modulation in Middle-aged to Elderly Individuals With Excessive Body Weight
The study is a single-center, randomized, double-blind, placebo-controlled study in middle-aged to elderly adults with excessive body weight. The study includes an 8-week intervention period followed by a 2-week follow-up period.
- Trial name
- myBIOM (NCT07453823)
- Testing
- Synbiotic
- Where
- Ireland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chr Hansen - part of Novonesis
Types of Colitis, Colonic Inflammation
Colitis Patterns in Patients With Lower GI Symptoms
This cross-sectional study aims to evaluate the patterns of colitis among patients presenting with lower gastrointestinal symptoms undergoing colonoscopy at Sohag University Hospitals.
- Conditions
- Types of Colitis, Colonic Inflammation, Lower Gastrointestinal Symptoms
- Trial name
- Patterns of C (NCT07515365)
- Testing
- No intervention ( observational study ), No intervention
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Post-Colonoscopy Gastrointestinal Symptoms
Effect of Escherichia Coli 5C (Colipral®) on Post-Colonoscopy Gastrointestinal Symptoms
This prospective, multicenter, randomized, double-blind, placebo-controlled clinical trial will evaluate the efficacy and safety of Escherichia coli 5C (Colipral®) in adult patients undergoing diagnostic colonoscopy.
- Trial name
- NCT07519616
- Testing
- Colipral®
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Liaquat University of Medical & Health Sciences
IBD (Inflammatory Bowel Disease), IBS (Irritable Bowel Syndrome)
Specimen and Data Collection for a Novel Biomarker Combination for the Differential Diagnosis of Inflammatory Bowel Disease and Irritable Bowel Syndrome.
This study will evaluate how well the a new stool test can distinguish inflammatory bowel disease (IBD) from non-IBD conditions compared with standard calprotectin testing and colonoscopy findings.
- Conditions
- IBD (Inflammatory Bowel Disease), IBS (Irritable Bowel Syndrome), Gastrointestinal Symptoms
- Trial name
- COMBI (NCT07471490)
- Where
- 2 sites in United States, Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- DiaSorin Inc.
Respiratory Disease, Gastrointestinal Diseases and Symptom
12 Steps of a Modified Handwashing Program on Health Outcomes and School Absenteeism
The goal of this clinical trial is to assess whether providing hand and respiratory hygiene interventions in primary school children reduces the incidence rate of absence episodes due to illness in children during an academic…
- Trial name
- Hand hygiene (NCT07467902)
- Testing
- Hand Hygiene Education Program
- Where
- Iraq
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
TRX Exercise, Bowel Habits
TRX Exercises and Gastrointestinal Health in Swimmers
Purpose Exercise-related gastrointestinal complaints are frequently reported in young athletes; however, evidence regarding the effects of resistance-based training modalities on bowel habits is limited.
- Conditions
- TRX Exercise, Bowel Habits, Gastrointestinal Symptoms, Swimming
- Trial name
- NCT07464509
- Testing
- Exercise, Randomized Controlled Trial
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Aksaray University
Abdominal Pain, Upper Gastrointestinal Symptoms
Robot-controlled Magnet-Assisted Capsule Endoscopy
Examination of the upper gastrointestinal tract (oesophagus, stomach and duodenum) involves passing a flexible tubular endoscope through the mouth into the stomach.
- Trial name
- MACE (NCT06030518)
- Testing
- Magnet Assisted Capsule Endoscopy
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Gastrointestinal Symptoms, Digestive Health
An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System
This clinical research study is being conducted to evaluate gut and digestive health before and after the use of a dietary supplement system over an eight-week period.
- Conditions
- Gastrointestinal Symptoms, Digestive Health, Gut Health
- Trial name
- NCT07421596
- Testing
- PhytoPower 1 and PhytoPower 2
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
Pancreatic Cancer, Pancreatic Diseases
PAN-CLO-BU (PANcreas-CLOstridium-BUtyricum)
This is a prospective, randomized, double-blind, single-center clinical trial designed to evaluate the effects of Clostridium butyricum CBM588 supplementation on postoperative diarrhea, gastrointestinal symptoms, and quality of…
- Conditions
- Pancreatic Cancer, Pancreatic Diseases, Gastrointestinal Symptoms, Clostridium Butyricum Miyairi
- Trial name
- PAN-CLO-BU (NCT07422103)
- Testing
- Clostridium butyricum CBM588 Strain
- Where
- Italy
- Volunteers
- 158 people
- Sponsor
- Casa di Cura Dott. Pederzoli
Gastrointestinal Problem, Anxiety
Effects of a Microalgae Extract Dietary Supplement on Gut Health, Anxiety, and Immune Function
This study will be conducted to determine the effect of daily Tetrasol consumption in supporting gut health using assessments of gastrointestinal symptoms (GSRS) and bowel habits (BSS) as primary outcome measures.
- Conditions
- Gastrointestinal Problem, Anxiety, Stress, Gastrointestinal Symptoms
- Trial name
- Tetrasol (NCT06425094)
- Testing
- Microalgae Extract Capsules
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Colorado State University