Clinical trials: Gastrointestinal Tolerance
Growth, Tolerance
Human Milk Oligosaccharides (HMOs) Post-market Study on Infants
Human milk oligosaccharides (HMOs) represent the third largest solid component of breast milk. Technology advancements made it possible to supplement infant formulas with HMOs (2'FL, LNnT).
- Conditions
- Growth, Tolerance, Adverse Event, Disorder of Intestine
- Trial name
- NEHMO (NCT04055363)
- Testing
- HMO-supplemented infant formula
- Where
- 6 sites in Spain
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Gastrointestinal Tolerance
Tolerance of Infants Fed a Hydrolysate Formula
This is a prospective, randomized, multicenter study to assess the tolerance of infant formulas.
- Trial name
- NCT03628183
- Testing
- Hydrolysate Infant Formula 1, Hydrolysate Infant Formula 2
- Where
- 5 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Satiation, Gastrointestinal Tolerance
Gastrointestinal Tolerance, Satiation and Sensory Acceptance of Yogurts Containing Dietary Fiber and Coffee Cascara Extract
Coffee processing byproducts, such as coffee cascara (outer skin and pulp of the coffee berry), have potential health promoting properties due to the presence of bioactive compounds.
- Conditions
- Satiation, Gastrointestinal Tolerance, Organoleptic Appreciation
- Trial name
- NCT03539146
- Testing
- Dietary fiber, Control yogurt
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Gastrointestinal, Tolerance
Gastrointestinal Tolerance of Erythritol-containing Beverages in Young Children
Purpose of this study: assess the maximum tolerated bolus dose of erythritol, delivered in a clear beverage, compared with placebo (saccharose) in 4-6 year old children.
- Trial name
- NCT02016703
- Testing
- Erythritol drink
- Where
- 3 sites in France
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Cargill
Gastrointestinal Tolerance
Behavior of Infants Fed Formula Supplemented With Prebiotics
To observe the effects of partially hydrolyzed formula supplemented with oligosaccharides on symptoms of formula intolerance in healthy term infants.
- Trial name
- NCT02757924
- Testing
- Infant formula supplemented with prebiotics
- Where
- 11 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Gastrointestinal Tolerance
Effect of Formula on Infant Behavior
This is a prospective, multi-center, single-arm study to evaluate the symptoms of formula intolerance in healthy term infants.
- Trial name
- NCT02746016
- Testing
- Infant Formula supplemented with Oligosaccharides
- Where
- 13 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Gastrointestinal Tolerance
Tolerance of Healthy Infants Fed Infant Formulas
The primary objective of this study is to assess the comparative gastrointestinal tolerance of normal term infants to two experimental milk-based powdered formulas compared with a standard milk-based powdered formula.
- Trial name
- NCT02401217
- Testing
- Phase 1- Arm 1 Infant Formula, Phase 2- Arm 2 Infant Formula, Phase 2- Arm 3 Infant Formula
- Where
- 6 sites in United States
- Volunteers
- 126 people
- Sponsor
- Abbott Nutrition
Gastrointestinal Tolerance
Gastrointestinal Tolerance of Infant Formula
The study objective is to evaluate the gastrointestinal tolerance of infant formula supplemented with prebiotics.
- Trial name
- NCT02322138
- Testing
- Experimental 1 Infant Formula, Experimental 2 Infant Formula, Reference Group
- Where
- 10 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Gastrointestinal Tolerance
Alternate Formula Feedings in Formula Intolerant Infants
This study assessed tolerance improvement of a formula change in healthy term infants with perceived intolerance to their current milk-based formula feeding.
- Trial name
- NCT02456805
- Testing
- Infant Formula 1, Infant Formula 2
- Where
- 8 sites in United States, Canada
- Volunteers
- 113 people
- Sponsor
- Abbott Nutrition
Gastrointestinal Tolerance
Soy Formula Feedings in Healthy, Term Infants
This study evaluates the GI tolerance and acceptability of soy formulas fed to healthy term infants with reported intolerance to a milk-based formula.
- Trial name
- NCT02456831
- Testing
- Experimental Infant Formula 1, Experimental Infant Formula 2, Experimental Infant Formula 3
- Where
- 7 sites in United States
- Volunteers
- 115 people
- Sponsor
- Abbott Nutrition
Gastrointestinal Tolerance
Evaluation of an Oral Nutrition Supplement
The objective of this study is to capture gastrointestinal tolerance (GI) information on a nutrient dense oral nutritional supplement (ONS) in healthy elderly subjects.
- Trial name
- NCT01902212
- Testing
- Oral Nutritional Supplement
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
C.Medical Procedure; Digestive System, Disorder of Upper Gastrointestinal Tract
Lidocaine Spray on an Endoscope to Improve Tolerance to Endoscopy
The investigators tested whether a new method which additional lidocaine spray on the tip of endoscope can increase the tolerance of examinee during endoscopy than conventional pharyngeal anesthesia alone.
- Conditions
- C.Medical Procedure; Digestive System, Disorder of Upper Gastrointestinal Tract, Tolerance
- Trial name
- NCT02307773
- Testing
- Case Group
- Where
- South Korea
- Volunteers
- 497 people
- Sponsor
- Cheju Halla General Hospital
Gastrointestinal Tolerance
Tolerance of Healthy Term Infants Fed Infant Formulas #3
The primary objective of this study is to assess the comparative gastrointestinal (GI) tolerance of normal term infants to six experimental milk protein-based powdered infant formulas.
- Trial name
- NCT00977964
- Testing
- Experimental milk protein infant formula Process A, Experimental milk protein infant formula Process B, Experimental milk protein infant formula Process C
- Where
- 15 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition