Clinical trials: Gastrointestinal Transit Time
Small Bowel Bacterial Overgrowth, Gastrointestinal Diseases
Transit Time and Bacterial Overgrowth Using SmartPill Capsule
The primary purpose of this exploratory study is to measure orocecal transit time using the SmartPill ambulant capsule technology and to compare this with the lactulose hydrogen breath test.
- Conditions
- Small Bowel Bacterial Overgrowth, Gastrointestinal Diseases, Stomach Diseases, Digestive System Diseases
- Trial name
- NCT00577772
- Testing
- Xifaxan, SmartPill, Lactulose hydrogen breath test (H_2BT)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Gastric Disease, Capsule Endoscopy
The Usage of Soda-Water in Gastric Preparation for Magnetically Controlled Capsule Endoscopy
Magnetically controlled capsule endoscopy (MCE) is a noninvasive technique (90.4% sensitivity, 94.7% specificity and 93.4% accuracy) without requiring sedation or air insufflation, which makes it welcomed by most of participants.
- Trial name
- NCT04479423
- Testing
- Soda-water instead of pure water to observe gastric filling
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Appetite, Gastrointestinal Transit
Ultra-Processed Foods, Palatability, Appetite, and Gastrointestinal Transit
The goal of this clinical trial is to learn how food processing level affects appetite and gastrointestinal transit time when meal palatability is changed. Participants will complete one screening visit and four test visits.
- Conditions
- Appetite, Gastrointestinal Transit, Food Processing, Food Palatability
- Trial name
- NCT07600281
- Testing
- Palatable Ultra-Processed Food Meal, Unpalatable Ultra-Processed Food Meal, Palatable Non-Ultra-Processed Food Meal
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Purdue University
Brain Injury, Constipation
Gastrointestinal Transit Time in Patients With Severe Acquired Brain Injury
Empirically patients with acquired brain injury (ABI) are often constipated. This is a major clinical issue. Nevertheless, this has only been sparsely studied.
- Trial name
- NCT02428790
- Volunteers
- 25 people
- Sponsor
- University of Aarhus
Gastrointestinal Transit Time
A Study on Gastrointestinal Transit Time at the Population Level
The goal of this study is to investigate the baseline of gastrointestinal transit time (GITT) and explore its relationship with other health indicators in 932 healthy adult volunteers.
- Trial name
- GITTPop (NCT07309250)
- Testing
- Diet
- Where
- Belgium
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Concentration-Time Profiles in Stomach & Intestine.
The Use of a Non-absorbable Marker for the Evaluation of the Gastrointestinal Transit
Aim of the study The aim of this study is to use Gabbroral® oral tablet formulation as marker for the evaluation of the gastrointestinal transit.
- Trial name
- NCT01780909
- Testing
- Paromomycin Sulfate Fasted State, Paromomycin Sulfate Fed State, Paromomycin Sulfate w/ domperidone
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Functional Constipation
Dose-Responsive Effect of Polydextrose on Whole Gut Transit Time
The aim of the study is to test the effect of polydextrose on whole gut transit time and gastrointestinal symptoms in a dose-responsive manner.
- Trial name
- PDX-Transit (NCT01540669)
- Testing
- Polydextrose, low dose, Polydextrose, medium dose, Polydextrose, high dose
- Where
- Italy
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Danisco
Gastroparesis, Slow Transit Constipation
Comparison of the Atmo Motility Gas Capsule System to the Reference Standard
The study objective is to demonstrate the equivalence of the Atmo Motility Gas Capsule System with the predicate SmartPill in measuring gastric emptying time and colonic transit time through examination of device agreement.
- Conditions
- Gastroparesis, Slow Transit Constipation, IBS
- Trial name
- NCT05718505
- Testing
- Atmo Motility Gas Capsule System, SmartPill Monitoring System
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Atmo Biosciences Pty Ltd
Inflammatory Bowel Disease, Crohn Disease
Retrospective Collection of PillCam SB Movies
Up to two hundred un-identified PillCam SB movies will be collected from 2 clinical sites, during up to 3 years and transferred to Given Imaging. Demographical data and medical history will be collected.
- Trial name
- OCEAN (NCT02707289)
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- Medtronic - MITG
Lactose Intolerants, Lactose Malabsorption
Milk Beta Caseins on Digestive Discomfort, Gastric Emptying
A1 and A2 β-casein are genetic variants of β-casein in cow's milk that differ by a single amino acid at position 67. Digestion of A1 β-casein may result in greater release of beta-casomorphin-7 (BCM-7), an opioid peptide that may…
- Conditions
- Lactose Intolerants, Lactose Malabsorption, Caseins
- Trial name
- Oral Naloxone (NCT07884123)
- Testing
- A1/A2 milk with oral naloxone, A1PF milk with oral naloxone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Purdue University
Crohn's Disease, Inflammatory Bowel Disease
GI Symptoms and Sleep Disturbances in Patients With Quiescent Crohns Disease
In this study we would like to clarify the effect of long lasting Crohn's Disease on motility of the gastrointestinal system in patient and the effect regarding sleep disturbances.
- Conditions
- Crohn's Disease, Inflammatory Bowel Disease, Sleep Disturbances
- Trial name
- NCT02245594
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Neuroendocrine Tumor
Gastrointestinal Motility in Patients With Neuroendocrine Tumors
We will study the total gastrointestinal transit time (GITT), gastric emptying and small intestine motility in NET patients before and after treated with somatostatin analogues and compare these to healthy subjects.
- Trial name
- NCT00789841
- Testing
- Magnetic Tracking System (MTS) and radio-opaque markers
- Where
- Denmark
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Guillain-Barre Syndrome, Constipation
Gastrointestinal Transit Time in Patients With Guillain-Barré Syndrome
Constipation is a common condition among patients with Guillain-Barré Syndrome. It is believed, that the constipation is caused by autonomic neuropathy.
- Trial name
- NCT02459808
- Where
- Denmark
- Sponsor
- University of Aarhus
Gastric Emptying, Healthy
Effect of Dexmedetomidine on Gastric Emptying and Gastrointestinal Transit
The aim of the study is to determine the effect of dexmedetomidine infusion on gastric emptying and oro-caecal transit time in healthy volunteers, judged by measuring plasma paracetamol concentrations after paracetamol ingestion…
- Trial name
- GADEX (NCT01084473)
- Testing
- Dexmedetomidine, Morphine
- Where
- Finland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Turku