Clinical trials: Gastrointestinal Tumor Surgery
Ulcerative Colitis, Rectal Cancer
Surgical and Oncological Outcomes in Patients With Ulcerative Colitis-associated Rectal Cancer
This is a retrospective observational study to investigate the short-term surgical outcomes, and long-term oncological outcomes of patients diagnosed with Ulcerative colitis and rectal cancer.
- Trial name
- UC-RectalK (NCT04659148)
- Testing
- Total proctocolectomy
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 40 people
- Sponsor
- Istituto Clinico Humanitas
Pancreatic Neuroendocrine Tumor
Pancreatic Neuroendocrine Tumour - Optimal Surgical Debulking or Not
Pancreatic neuroendocrine tumours (pan-NETs) are neoplasms arising from the endocrine cells of the pancreas. Although pan-NET are quite rare, the incidence is on the rise and together with other abdominal neuroendocrine tumours…
- Trial name
- PANTODON (NCT07273409)
- Testing
- Debulking surgery
- Where
- 4 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Uppsala University
Squamous Cell Carcinoma, Adenocarcinoma
Chemoradiation and Panitumumab for Esophageal Cancer
A consistent finding in many studies in patients with operable esophageal and gastro-esophageal junction (GEJ) cancer is that response to preoperative therapy, particularly the absence of residual disease in the surgical…
- Conditions
- Squamous Cell Carcinoma, Adenocarcinoma, Esophageal Cancer, Gastro-esophageal Junction Cancer
- Trial name
- NCT01077999
- Testing
- Carboplatin, Paclitaxel, panitumumab
- Where
- Netherlands
- Volunteers
- 78 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pancreas Cancer, Pancreas Neoplasm
Survival, Quality of Life and Resectability in Locally Advanced Pancreatic Cancer
This study aims to assess overall survival, quality of life and resection rates in locally advanced pancreatic cancer
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Pancreas Disease, Pancreas Adenocarcinoma
- Trial name
- SQUARE (NCT05356039)
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Umeå University
Colorectal Cancer, Postoperative Pain
Ultrasound-Guided Erector Spinae Plan Block for Colorectal Surgery
Colorectal cancer is a common and lethal disease. It still remains the third most common cause of cancer death in women and the second leading cause of death in men.
- Trial name
- NCT04313764
- Testing
- Bupivacaine Hcl 0.25% ESP block, Bupivacaine Hcl 0.25% infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Ataturk University
Extrahepatic Bile Duct Cancer, Gallbladder Cancer
Capecitabine or Observation After Surgery in Treating Patients With Biliary Tract Cancer
RATIONALE: Drugs used in chemotherapy, such as capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer
- Trial name
- NCT00363584
- Testing
- capecitabine, clinical observation, adjuvant therapy
- Where
- 46 sites in United Kingdom
- Volunteers
- 360 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Pancreatic Cancer
A Study of Gemcitabine/Nab-paclitaxel and Radiation Therapy Followed by Surgery in Patients With Advanced Pancreatic Cancer
This is a phase 1 (the first phase in testing a new drug, to see how safe a new drug or new indication/population ) and phase 2 (the second phase in testing a new drug or new indication/population to see how effective the drug…
- Trial name
- NCT02481635
- Testing
- Gemcitabine, Nab-paclitaxel, Radiation Therapy
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University Health Network, Toronto
Peritoneal Carcinosis (PC)
Treatment of Primary Peritoneal Carcinosis of Digestive Origin Using Cytoreductive Surgery and Hyperthermic Intraoperative Peritoneal Chemotherapy With Mitomycin C and Irinotecan
This is an open, non-randomized, phase I-II, pilot study, which evaluates the combination of optimum cytoreductive surgery and hyperthermic intraoperative peritoneal chemotherapy (HIPEC) with mitomycin C (MMC) and irinotecan.
- Trial name
- NCT01226550
- Testing
- cytoreductive surgery and HIPEC
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Hospices Civils de Lyon
Colon Cancer, Benign Colon Diseases
Evaluation of Microcirculation in Colon Wall and Bowel Anastomosis by Laser Induced Fluorescence Video Angiography
The aim of the study is to describe utility of dynamic fluorescence videoangiography of indocyanine green (ICG) in gastrointestinal surgery, for evaluation of microcirculation in colon wall and anastomosis before and after…
- Trial name
- NCT01419860
- Testing
- Elective colon resection
- Where
- Norway
- Volunteers
- 4 people
- Sponsor
- Ostfold Hospital Trust
Morbid Obesity, Hernia
Minimally Invasive Surgery (MIS) Database for the Purpose of Research
The Minimally Invasive Surgery Team (MIST) are establishing a separate research database to find out more about patient's undergoing minimally invasive surgery (laparoscopic , open and robot assisted) procedures at UCSD.
- Conditions
- Morbid Obesity, Hernia, Colorectal Cancer, Laparoscopy
- Trial name
- NCT00535990
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Patient Empowerment, Low Anterior Resection Syndrome
Interactive Online Informational and Peer Support App for Patients with Low Anterior Resection Syndrome
After surgery for rectal cancer, many people undergo changes in bowel habits, which may include the need to empty their bowels more often, accidental leakage of stool or gas, the sudden urge to go to the bathroom, and more.
- Conditions
- Patient Empowerment, Low Anterior Resection Syndrome, Colo-rectal Cancer, Peer Group
- Trial name
- NCT04469426
- Testing
- Interactive online informational and peer support app
- Where
- 5 sites in Canada
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Colorectal Cancer
Use a Wearable Devices to Observe Complications of Mobilization for Colorectal Cancer After Surgery
This study aims to help patients recover faster after colorectal cancer surgery by using wearable devices to monitor early movement.
- Trial name
- NCT07289685
- Where
- Taiwan
- Volunteers
- 192 people
- Sponsor
- Chang Gung Memorial Hospital
Gastric Cancer
Surgery for Obstructed Gastric Carcinoma
The goal of this clinical trial is to find the best treatment for obstructed gastric carcinoma in gastric cancer patients. It will include all patients with obstructed gastric cancer with different ages and sex who consented to…
- Trial name
- NCT07435025
- Testing
- palliative gastric resection, palliative bypass
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Zagazig University
Lower Gastrointestinal Neoplasms Benign, Pancreas Cancer
The Effects of Perioperative Painting Art Therapy (LOM® Solution Centered Art Therapy) in Surgical Patients
The investigators want to study whether the use of painting art therapy has an influence on the quality of life, the complication rate and the general outcome of major abdominal surgery.
- Conditions
- Lower Gastrointestinal Neoplasms Benign, Pancreas Cancer, Posttraumatic Stress Disorder, Depression, Anxiety
- Trial name
- NCT04524260
- Testing
- perioperative painting art therapy (LOM® solution centered art therapy), perioperative painting art therapy (LOM® solution centered art therapy) - control
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Intestinal Neoplasm, Perioperative Care
Simvastatin in Colorectal Surgery
Statins (HMG-CoA reductase inhibitors) are a widely used class of cholesterol-lowering drugs that have an established role in the medical management of cardiovascular disease.
- Trial name
- StatCol (NCT00994903)
- Testing
- Simvastatin
- Where
- 3 sites in New Zealand
- Volunteers
- 132 people
- Sponsor
- University of Auckland, New Zealand
Liver Tumor; Surgery, 3D Printing
SH-LPS System in Preoperative Planning for Liver Resection
Effective preoperative planning and real-time intraoperative guidance are crucial for performing accurate liver resections. To address this need, the researchers have designed advanced 3D-printed liver models using a self-healing…
- Conditions
- Liver Tumor; Surgery, 3D Printing, Preoperative Planning
- Trial name
- NCT06911086
- Testing
- 3D printed models, CT or MRI image
- Volunteers
- 100 people
- Sponsor
- Zhejiang Cancer Hospital
Rectal Cancer, Surgery
Multicenter Study on Suprapubic Catheterization Versus Transurethral Catheterization in Laparoscopic Surgery for Rectal Cancer
Compared with traditional open proctectomy, laparoscopic surgery is associated with less pain, earlier recovery, and better cosmetic outcome, and its long-term oncologic outcomes have been demonstrated.
- Trial name
- MSSPC (NCT02728427)
- Testing
- Suprapubic catheterization using central venous catheter(CVC-2 7F), Transurethral catheterization using Foley catheter
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Gastro-Intestinal Stromal Tumour
Masitinib in Patients With Localized, Primary GIST After Complete Surgery and With High Risk of Recurrence
The objective is to compare the efficacy and safety of masitinib at 4.5 mg/kg/day to placebo in the treatment of patients with localized, primary gastrointestinal stromal tumor (GIST) after complete surgery and with high risk of…
- Trial name
- NCT02009423
- Testing
- Masitinib
- Volunteers
- 7 people
- Sponsor
- AB Science
Pancreatic Neoplasms
Circulating Epigenetics in Pancreatic Surgery
The overall objective of the study is to assess DNA-methylation changes in circulating blood cells and cell free DNA in plasma from patients undergoing the Whipples procedure for pancreatic caner
- Trial name
- NCT04947696
- Testing
- Blood sampling
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Gastric Adenocarcinoma, Stomach Neoplasms
Conversion Therapy Plus Surgery and Radiotherapy for Retroperitoneal Nodal Metastases in Gastric Cancer
This is a randomized, controlled, multicenter phase II clinical trial evaluating the efficacy and safety of conversion therapy combined with radical gastrectomy and adjuvant radiotherapy targeting para-aortic (station 16) lymph…
- Trial name
- NCT07007182
- Testing
- SOX regimen, CAPEOX regimen, PD-1 inhibitor
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Jinbo Yue
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