Clinical trials: Gastrointestinal Tumor Surgery
Sigmoid Neoplasms
Length of Hospital Stay, Nursing Hours and Recovery After Laparoscopic Versus Open Colon Resection Without Fast Track
A blinded randomized trial. Length of hospital stay, nursing hours and recovery after laparoscopic versus open colonic resection without fast track.
- Trial name
- NCT01127425
- Testing
- laparoscopic colonic resection, laparoscopic sigmoid resection
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Colorectal Neoplasms, Urologic Neoplasms
A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery
This is a prospective, single center, multispecialty study that aimed to evaluate the clinical feasibility and safety of single port surgery and NOTES (mainly transanal and transoral surgery) using a novel single port robotic…
- Conditions
- Colorectal Neoplasms, Urologic Neoplasms, Urologic Diseases, Nasopharyngeal Neoplasms
- Trial name
- NCT03010813
- Testing
- Robotic single port surgery and NOTES
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Chinese University of Hong Kong
Stomach Neoplasms
No Antimicrobial Prophylaxis for Laparoscopic Distal Gastrectomy
The aim of this study is to evaluate the feasibility and safety of no use of antimicrobial prophylaxis during laparoscopic distal gastrectomy for gastric carcinoma.
- Trial name
- KSWEET-01 (NCT02200315)
- Testing
- No Antimicrobial prophylaxis
- Where
- 3 sites in South Korea
- Volunteers
- 98 people
- Sponsor
- Korean South West East Gastric Surgery Group
Colorectal Liver Metastases, Colorectal Neoplasms
Multimodal Survival Prediction Model for Colorectal Liver Metastases Post-Operation
The purpose of this study is to construct and validate a multimodal survival prediction model by integrating 3D radiomics features derived from preoperative magnetic resonance imaging (MRI) with systemic clinical baseline…
- Conditions
- Colorectal Liver Metastases, Colorectal Neoplasms, Liver Neoplasms
- Trial name
- NCT07830576
- Testing
- Multimodal Predictive Evaluation
- Where
- China
- Volunteers
- 205 people
- Sponsor
- Anhui Provincial Hospital
Pancreatic Neoplasms
Analgesia and Pancreatic Cancer Surgery
Long-term survival for patients with pancreatic carcinoma is low, even following resection, the 5-year survival rate of patients ranges from 10 to 25%1.
- Trial name
- NCT01929915
- Testing
- Epidural patient controlled analgesia, Intravenous patient controlled analgesia
- Where
- Taiwan
- Volunteers
- 135 people
- Sponsor
- National Taiwan University Hospital
Post-operative Pneumonia, Lung Cancer
Prevention of Post-operative Pneumonia (POPP)
Postoperative pneumonia is a major complication in patients undergoing thoracic surgery. It leads to considerable morbidity and contributes to perioperative morbidity.
- Conditions
- Post-operative Pneumonia, Lung Cancer, Esophageal Cancer
- Trial name
- POPP (NCT01446874)
- Testing
- 0.12% chlorhexidine solution
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Washington University School of Medicine
Colorectal Neoplasms
Effect of Preoperative Immunonutrition Versus Standard Oral Nutrition in Patient Undergoing Colorectal Surgery.
This is a randomised controlled clinical trial . The investigators aim to compare the effects of preoperative immune modulating enteral nutrition and standard oral nutrition supplement on clinical outcomes of the patients undergo…
- Trial name
- NCT06128798
- Testing
- Oral Impact, Nutren Optimum
- Where
- Malaysia
- Volunteers
- 58 people
- Sponsor
- Hospital Universiti Sains Malaysia
Gastric Cancer, Pancreatic Cancer
The Impact of Immunostimulating Nutrition on the Outcome of Surgery
The aim of the study was to assess the clinical effect of immunostimulatory enteral and parenteral nutrition in patients undergoing resection for gastrointestinal cancer.
- Trial name
- NCT00558155
- Testing
- peptisorb, Stresson, Parenteral nutrition
- Where
- Poland
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Esophageal Cancer
Cetuximab and Radiation Therapy for Surgically Resectable Esophageal and Gastroesophageal (GE) Junction Carcinomas
The interaction of epidermal growth factor receptor (EGFR) inhibitory agents such as cetuximab combined with radiation shows promising results.
- Trial name
- NCT00319735
- Testing
- Radiation Therapy, Surgery, Tissue Sample
- Where
- 7 sites in United States
- Volunteers
- 41 people
- Sponsor
- Nasser Hanna, M.D.
Cancer of Digestive System, Ovarian Cancer
Feasibility Study for Robotic Endomicroscopy to Better Define Resection Strategies (PERSEE)
This study aims at demonstrating the feasibility of probe-based confocal laser endomicroscopy (pCLE) and needle-based confocal laser endomicroscopy (nCLE).
- Trial name
- PERSEE (NCT02312167)
- Testing
- confocal laser endomicroscopy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Institut Mutualiste Montsouris
Colon Cancer, Diverticulum, Colon
ERAS Lazio Network Clinical Registry
Enhanced recovery after surgery (ERAS) protocols are programs aiming to implement patients recovery following surgical procedures developed about 25 years ago.
- Trial name
- ENeRgy (NCT03353311)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- PERSIANI ROBERTO
Cancer of Esophagus, Cancer of the Esophagus
Study of Inspiratory Muscle Training for Patients Undergoing Esophageal Surgery
To obtain definitive evidence for the effectiveness of a short preoperative inspiratory muscle training (IMT) protocol on the morbidity and recovery from an esophageal surgical resection.
- Conditions
- Cancer of Esophagus, Cancer of the Esophagus, Esophageal Cancer, Esophagus Cancer
- Trial name
- NCT02843750
- Testing
- Inspiratory Muscle Training-Rehabilitation, Questionnaires
- Where
- United States
- Sponsor
- Mayo Clinic
Esophageal Cancer, Gastric Cancer (Diagnosis)
Exercise Training After Upper Gastrointestinal Cancer Surgery
This randomized controlled trial aims to determine the optimal exercise intensity for improving postoperative recovery in patients with upper gastrointestinal cancer.
- Conditions
- Esophageal Cancer, Gastric Cancer (Diagnosis), Upper Gastrointestinal Cancer
- Trial name
- NCT07561840
- Testing
- High-Intensity Interval Training (HIIT), Low-Intensity Continuous Training (LICT)
- Where
- 2 sites in Japan
- Volunteers
- 171 people
- Sponsor
- Kansai Medical University
Upper Gastrointestinal Disorders
CPET and Outcome After Oesophagogastric Cancer Surgery
Primary Aim: The present study is a retrospective analysis of prospectively collected clinical data. Anonymized data from patients collected during routine clinical care from 9 units in the United Kingdom who undertake upper…
- Trial name
- NCT03637647
- Testing
- Cardiopulmonary exercise testing
- Where
- United Kingdom
- Volunteers
- 611 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Colorectal Cancer, Liver Metastases
Preoperative Irinotecan Drug-eluting Beads for Patients With Unresectable Colorectal Liver Metastasis
Trans arterial chemoembolization using Irinotecan Drug-eluting Beads before liver surgery for patients with primarily unresectable colorectal liver metastasis
- Trial name
- NCT04912258
- Testing
- Trans arterial chemoembolization with Irinotecan Drug-eluting Beads
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fudan University
Hepatocellular Carcinoma
Safety and Efficacy of Autoimmune Cell Therapy for Patients With Hepatocellular Carcinoma
In this study, safety and effects of IPM001 vaccine on human hepatocellular carcinoma are going to be investigated, IPM001 is a neoantigen/tumor-specific antigen sensitized autoimmune cell injection
- Trial name
- NCT05105815
- Testing
- IPM001
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Huashan Hospital
Colorectal Cancer
Long Term Effect of Trimodal Prehabilitation Compared to ERAS in Colorectal Cancer Surgery.
Elective surgery is the most effective treatment option for colorectal cancer, however it has been recognized to be associated with high morbidity and mortality risks.
- Trial name
- Prehab_2 (NCT04595604)
- Testing
- Trimodal rehabilitation + ERAS, ERAS + nutritional prehabilitation
- Where
- 2 sites in Hungary
- Volunteers
- 500 people
- Sponsor
- St. Borbala Hospital
Colorectal Cancer
Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as fluorouracil and leucovorin, work in different ways to stop the growth of tumor cells, either by killing the cells or…
- Trial name
- NCT00296608
- Testing
- fluorouracil, leucovorin calcium, conventional surgery
- Volunteers
- 762 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Achalasia, Gastric Outlet Obstruction
Endoscopic Surgery for Gastrointestinal Disorders: A Multicenter Registry Study
Currently, there is limited multi-center data on endoscopic surgery outcomes in western populations. Evaluation of these measurement would help the investigators compare them to conventional treatment modalities within current…
- Conditions
- Achalasia, Gastric Outlet Obstruction, Gastroparesis, GERD
- Trial name
- NCT05041608
- Testing
- Endoscopic Surgery
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University
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