Clinical trials: Gastrointestinal Tumor Surgery
Rectal Neoplasms
Endoscopic Submucosal Dissection vs Local Laparoscopic Surgical Resection (TAMIS/TEO) in Early Rectal Neoplasias
A multicenter non-inferiority randomized clinical trial to compare Endoscopic treatment (ESD) and Minimally Invasive Laparoscopic Local Surgical Treatment (TAMIS or TEO) for early rectal neoplastic lesions (adenoma \& T1CRC)…
- Trial name
- DSETAMIS2018 (NCT03959839)
- Testing
- ESD, TAMIS, TEO
- Where
- 3 sites in Spain
- Volunteers
- 70 people
- Sponsor
- Dr. Alberto Herreros de Tejada Echanojáuregui
Locally Advanced Pancreatic Adenocarcinoma
Surgery for Locally Unresectable Pancreatic Cancer
Pancreatic cancer is a severe disease often diagnosed at an advanced stage, when surgery is not possible. New chemotherapy treatments can sometimes shrink the tumor and make surgery an option.
- Trial name
- ROBIN (NCT07241663)
- Testing
- Questionnaire
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliera di Padova
Hepatocellular Carcinoma, Surgery
Surgical Therapy and Survival in HCC/ C.F. Zhang et al.
This study utilizes a new method to explore compare the overall survival (OS) and cancer-specific survival (CSS) in patients aged 18-45 years with stage I-II HCC who underwent different types of surgery.
- Trial name
- NCT04820712
- Where
- China
- Volunteers
- 664 people
- Sponsor
- Linzhu Zhai
Liver Surgery, MINIMALLY INVASIVE LIVER SURGERY
Safety and Economics of Parenchymal Transection in Minimally Invasive Liver Surgery
LIVER-MIND 2 is a multicentre, observational, retrospective registry coordinated by the SICE HPB and Minimally Invasive Surgery Working Group, enrolling consecutive adults undergoing elective minimally invasive (laparoscopic…
- Conditions
- Liver Surgery, MINIMALLY INVASIVE LIVER SURGERY, Liver Neoplasm
- Trial name
- LIVER-MIND 2 (NCT07750275)
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- University of Molise
Anxiety, Gastric Carcinoma
Educational Brochure in Preparing Patients With Gastric Cancer and Their Caregivers for Recovery After Surgery
This pilot clinical trial studies an educational brochure in preparing patients with gastric cancer and their caregivers for recovery after surgery.
- Conditions
- Anxiety, Gastric Carcinoma, Stress
- Trial name
- NCT02334332
- Testing
- Educational Intervention, Standard Follow-Up Care, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Colorectal Cancer, Urologic Cancer
Fluid Challenge and Plasma Volume, During Surgery
A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique.
- Conditions
- Colorectal Cancer, Urologic Cancer, Gynecologic Cancer, Colorectal Disorders
- Trial name
- FC-VE (NCT05726136)
- Testing
- acetated Ringers, albumin 5%, albumin 20%
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Joachim Zdolsek
ColoRectal Cancer, Liver Metastasis Colon Cancer
COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation
The primary objective is to prove non-inferiority of thermal ablation compared to hepatic resection in patients with at least one resectable and ablatable colorectal liver metastases (≤3cm) and no extrahepatic disease.
- Conditions
- ColoRectal Cancer, Liver Metastasis Colon Cancer, Liver Metastases, Surgery
- Trial name
- COLLISION (NCT03088150)
- Testing
- Thermal ablation, Surgical resection
- Where
- Netherlands
- Volunteers
- 618 people
- Sponsor
- Amsterdam UMC, location VUmc
Pancreatic Cancer
Radiotherapy With GX Regimen as Adjuvant Therapy for High-risk Patients Following Pancreatic Cancer Surgery
Pancreatic cancer is a highly fatal malignant tumor. Simple surgical operations can no longer meet the treatment needs of pancreatic cancer patients.
- Trial name
- NCT07632118
- Testing
- Radiotherapy + GX, GX group
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Pancreatic Neuroendocrine Tumor
Pancreatic Neuroendocrine Tumor：Factor of Surgery Influencing Survival
Investigator determined the factor of surgery associated with the survival of pancreatic neuroendocrine tumor.
- Trial name
- NCT02624154
- Testing
- pancreatectomy
- Volunteers
- 2 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Colorectal Cancer
Intraoperative Flow Cytometry In Colorectal Cancer
This study was designed to investigate the efficacy of flow cytometry to accurately identify between normal and cancer cells in colon epithelium in humans diagnosed with colorectal cancer.
- Trial name
- NCT05261542
- Testing
- flow cytometry
- Where
- Greece
- Volunteers
- 106 people
- Sponsor
- University Hospital, Ioannina
Liver Cancer, Recurrence
Factors Influencing the 3-Year Recurrence of Liver Carcinoma After Surgery
Objective: 1. To study the factors that influence the 3- year recurrence of liver carcinoma after surgery 2. To study the related factors affecting recurrence of liver carcinoma after surgery
- Trial name
- NCT02941861
- Testing
- Recurrence Rate of HCC after surgery, Recurrence Rate of CCA after surgery
- Volunteers
- 67 people
- Sponsor
- Ruechuta Molek
Colorectal Cancer, Surgery
Future of Colorectal Cancer Surgery
Colorectal cancer is the third most common cancer in the UK and Ireland, it is the second commonest cancer in both men and women.
- Trial name
- FOCCuS1 (NCT04220242)
- Testing
- Video recordings with analysis thereafter applied, Examination of microsections of tissue excised for the purposes of cancer resection, Cancer organoid development and testing
- Where
- Ireland
- Volunteers
- 250 people
- Sponsor
- Mater Misericordiae University Hospital
Colorectal Cancer
CAPEOX vs Observation in Colorectal Cancer Patients With Positive MRD
Patients with stage Ⅰ colorectal cancer or stage Ⅱ colon cancer usually have a good prognosis and are not recommended to receive adjuvant chemotherapy after radical surgery.
- Trial name
- NCT05699746
- Testing
- Capecitabine tablets, Oxaliplatin
- Where
- 4 sites in China
- Volunteers
- 38 people
- Sponsor
- Zhejiang University
Hepatocellular Carcinoma (HCC)
Individualized Surgical Guidance in HCC-BDTT
The Rboost causal model can identify patients who are most likely to benefit among HCC-BDTT patients. Adherence to the individualized recommendation improves survival.
- Trial name
- NCT07483242
- Testing
- Bile Duct Resection
- Where
- China
- Volunteers
- 151 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Stomach Neoplasms, Colonic Neoplasms
Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients
Postoperative delirium（POD）is a common complication that can directly affect important clinical outcomes, and exert an enormous burden on patients, their families, hospitals, and public resources.
- Conditions
- Stomach Neoplasms, Colonic Neoplasms, Rectal Neoplasms, Sigmoid Neoplasms
- Trial name
- NCT05068180
- Testing
- low-dose neuroleptanalgesia
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Anastomotic Leak, Colorectal Cancer
Anastomotic Leakage After Colorectal Surgery.
Anastomotic leakage (AL) is a severe complication after colorectal surgery, with incidence rates of 2-30%. This prospective, single-center observational cohort study aims to identify and quantify independent risk factors for AL…
- Conditions
- Anastomotic Leak, Colorectal Cancer, Diverticulitis
- Trial name
- AL (NCT07144683)
- Testing
- Patients Undergoing Colorectal Resection with Anastomosis
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Hepatocellular Carcinoma, Hepatectomy
Textbook Outcomes of Right Hemihepatectomy in Patients With Hepatocellular Carcinoma
Although traditional open right hemihepatectomy is a mature technique, the incision is usually very large; Intraoperative bleeding may be excessive, and postoperative liver failure is also prone to occur.
- Conditions
- Hepatocellular Carcinoma, Hepatectomy, Laparoscopic Hepatectomy
- Trial name
- NCT06950827
- Testing
- laparoscopic right hemihepatectomy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- West China Hospital
Colorectal Cancer, Gastric Cancer
Performing Laparoscopic Surgery for Colorectal and Gastric Cancer Outside the Primary Registered Medical Institution
This study investigates the safety and feasibility of performing laparoscopic surgery for colorectal and gastric cancer inside versus outside the primary registered medical institution under multi-sites practice (MSP) policy.
- Trial name
- NCT04834661
- Testing
- surgery inside the primary institution, surgery outside the primary institution
- Where
- China
- Volunteers
- 1,130 people
- Sponsor
- Shanghai Minimally Invasive Surgery Center
Colorectal Cancer, Surgery
A Mobile Application to Improve Postoperative Outcomes in Colorectal Cancer
The unplanned readmission rate after colorectal cancer surgery is still high, despite the implementation of enhanced recovery programs.
- Trial name
- RAISe-Care (NCT06302751)
- Testing
- Care 4 Today ® (Johnson and Johnson) mobile app
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Istituto Clinico Humanitas
Gastrointestinal Stromal Tumor of Duodenum
Outcome After Surgical Resection of Gastrointestinal Stromal Tumors (GIST) in the Second Part of Duodenum
it is hypothesized that long term outcomes of localized resection of GIST tumors located in the second part of the duodenum are comparable to those of the traditional treatment by radical resection of the head o pancreas and the…
- Trial name
- GIST (NCT04487002)
- Testing
- surgical resection
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Alexandria University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.