Clinical trials: Gastrointestinal Vascular Conditions
Colorectal Cancer
Influence of the Surgical Technique Used for Colectomies on the Concentration of Circulating Tumor DNA and the Presence of Circulating Tumor Cells: Comparison of the "no Touch" Technic With Either First Clamping of the Mesenteric Vessels or First Mobilization of the Tumor Followed by Clamping.
Colectomy is the most commonly used therapeutic approach for the treatment of non-metastatic colorectal cancer. This approach is generally very effective however the rate of recurrence and the appearance of metachronous…
- Trial name
- ADNCHIR (NCT03809403)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastrointestinal Vascular Conditions, Arteriosclerosis
Covered Stents Versus Bare-Metal Stents
To compare the outcome of revascularisation the gastrointestinal arteries using covered stents compared to bare-metal stents in patients with CGI.
- Conditions
- Gastrointestinal Vascular Conditions, Arteriosclerosis, Lifestyle-related Condition, Stenosis
- Trial name
- NCT02428582
- Testing
- Covered stent (Atrium Type V12), Bare stent (Brand Cordis Type Palmaz Blue)
- Where
- Netherlands
- Volunteers
- 84 people
- Sponsor
- Erasmus Medical Center
Obesity, Obesity, Morbid
Biological Sample Repository for Gastrointestinal Disorders
The goal of this observational study has the purpose of collecting biological samples from obese patients undergoing evaluation for weight loss by means of medical or endoscopic therapies; and of post bariatric surgery patients…
- Conditions
- Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder
- Trial name
- NCT05874726
- Testing
- Blood Collection, Urine Collection, Tissue Sample Collection
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Pichamol Jirapinyo, MD, MPH
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Ontario
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-ON (NCT02742597)
- Testing
- TIP / IMPACT Plus Care Coordination
- Where
- 9 sites in Canada
- Volunteers
- 175 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Deglutition Disorders, Lateral Medullary Syndrome
Cortical Function Changes During Swallowing in Patients With Dysphagia in Lateral Medullary Syndrome
The goal of this observational study is to detect the alteration of cortical activation and functional connectivity during swallowing in patients with Lateral Medullary Syndrome (LMS) dysphagia by functional near infrared…
- Trial name
- NCT06208020
- Testing
- Functional near-infrared spectroscopy (fNIRS) detection
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Melanoma, Meningioma
T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer
Background: The National Cancer Institute (NCI) Surgery Branch has developed an experimental therapy for treating patients with cancer that involves taking white blood cells from the patient, growing them in the laboratory in…
- Conditions
- Melanoma, Meningioma, Breast Cancer, Non-Small Cell Lung Cancer
- Trial name
- NCT01967823
- Testing
- Anti-NY ESO-1 mTCR PBL, Cyclophosphamide, Fludarabine
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Cancer Institute (NCI)
Cirrhosis, Variceal Bleeding
EBL Versus EBL and Propranolol for the Prevention of Variceal Rebleeding in Pts With Previous Variceal Treatment
This study is performed to compare the efficacy and safety of EBL alone and EBL combined with propranolol in patients who were previously performed endoscopic variceal treatment.
- Trial name
- NCT00966082
- Testing
- endoscopic band ligation, endoscopic band ligation+Propranolol
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Korea University
Liver Fibroses, HepatoCellular Carcinoma
Long-term Outcomes of Chronic Hepatitis C Patients Post Sofosbuvir-based Treatment
Primary Objective: To evaluate the long-term outcomes including liver related morbidity, mortality and hepatocellular carcinoma (HCC) development as compared to those of historical control with interferon(IFN)-based treatment.
- Conditions
- Liver Fibroses, HepatoCellular Carcinoma, Cryoglobulinemia, Metabolic Disease
- Trial name
- LONGHEAD (NCT03042520)
- Testing
- Observation only
- Where
- 26 sites in South Korea, Taiwan
- Volunteers
- 200 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Colorectal Adenoma, Colorectal Neoplasms
Adenoma Detection Rate in Colonoscopy Performed With EndoRings
The study is designed to examine whether colonoscopy using an EndoRings cap has a higher adenoma detection rate than conventional colonoscopy.
- Trial name
- NCT03219918
- Testing
- EndoRings II Distal Attachment
- Where
- Denmark
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Hemorrhoids, Liver Cirrhosis
Polidocanol Foam in Hemorrhoidal Disease in Patients With Liver Cirrhosis
Hemorrhoidal disease (HD) is a common health problem, affecting up to 38,9% of adult population. HD is also a common finding in up to 36% of cirrhotic patients, as hemorrhoidal plexus is a possible site of portosystemic venous…
- Trial name
- NCT05807425
- Testing
- Polidocanol foam sclerotherapy
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Universidade do Porto
Gastrointestinal Bleeding, Acute Coronary Syndrome
Factors Contributing To Cardiovascular Morbidity and Mortality in Patients With Gastrointestinal Bleeding
The rate of complication and death of patients with acute digestive tract bleeding is increased in the setting of acute coronary heart disease.
- Trial name
- NCT00401908
- Where
- United States
- Sponsor
- Maimonides Medical Center
Hemorrhoids, Fissure in Ano
Pre-Emptive Analgesia in Ano-Rectal Surgery
The perianal region is the region around the anus. Administering a pain medication before a surgery starts is called preemptive analgesia.
- Conditions
- Hemorrhoids, Fissure in Ano, Rectal Fistula, Anal Condyloma
- Trial name
- PEAARS (NCT02402543)
- Testing
- Gabapentin, Ketamine, Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Vermont
Cirrhosis, Splenectomy; Status
Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy（ESAWAAPT）
The purpose of this study is to determine whether Apixaban, Warfarin and Aspirin Anticoagulation are effective and safe in Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients after Laparoscopic Splenectomy
- Conditions
- Cirrhosis, Splenectomy; Status, Venous Thrombosis, Hypertension, Portal
- Trial name
- NCT04645550
- Testing
- Apixaban, Warfarin, Aspirin
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Northern Jiangsu People's Hospital
Dysphagia, Stroke
Investigation of the Effect of Neuromuscular Electrical Stimulation Techniques on Suprahyoid Muscles and Swallowing Function in Acute Hemiparetic Stroke Patients
This randomized controlled trial aims to investigate the effects of sensory, motor, and modified combined neuromuscular electrical stimulation (NMES) protocols on swallowing function in patients with acute stroke-related…
- Conditions
- Dysphagia, Stroke, Hemiparesis
- Trial name
- NMESWAL (NCT07445204)
- Testing
- Conventional Swallowing Therapy, Vitalstim-Sensory NMES, Vitalstim-Motor NMES
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Arel University
Enterocolitis, Necrotizing, Bacteremia
Antibiotic "Dysbiosis" in Preterm Infants
Prolonged antibiotic use in preterm neonates has significant consequences on the developing intestinal microbiome, metabolome and host response, predisposing the neonate to various major morbidities, including necrotizing…
- Conditions
- Enterocolitis, Necrotizing, Bacteremia, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage
- Trial name
- NCT02784821
- Testing
- Antibiotic, Gastric fluid, Breast milk
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Florida
Dementia, Depression
Vegetarian Diet and Chronic Degenerative Diseases
To investigate the prospective association between a vegetarian diet and chronic degenerative diseases in two cohorts of Taiwanese Buddhists
- Conditions
- Dementia, Depression, Cardiovascular Diseases, Stroke
- Trial name
- NCT03470584
- Testing
- Diet Exposure
- Where
- Taiwan
- Volunteers
- 18,064 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Subarachnoid Hemorrhage, Intracerebral Hemorrhage
Safety and Efficacy of Nicardipine for the Control of Blood Pressure After SAH
The purpose of this research is to explore ways to improve and simplify control of blood pressure in patients with SAH or ICH. This research will be done by comparing tow different medications that are routinely used to help…
- Trial name
- NCT00490464
- Testing
- Nicardipine and Nipride
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- University of Illinois Chicago
Gastrointestinal Bleeding of Unknown Origin, Gastrointestinal Vascular Malformation
Retreatment and Its Efficiency of Thalidomide for Vascular Malformation Patients With Failure of First Course Treatment
Background: Repeated episodes of bleeding from gastrointestinal vascular malformations refractory to endoscopic or surgical therapy often pose a major therapeutic challenge.
- Conditions
- Gastrointestinal Bleeding of Unknown Origin, Gastrointestinal Vascular Malformation, Thalidomide Efficiency
- Trial name
- NCT02301949
- Testing
- Thalidomide
- Where
- China
- Sponsor
- Zhizheng Ge
Diabetes Mellitus, Type 2, Liver Fibrosis
Effect of an Early Time Restricted Eating Mediterranean Diet Compared to Naltrexone/Bupropion on Liver Fibrosis in People With Cardiometabolic Risk Factors in a Hospital Outpatient Clinic (MEDFAST-study)
In the Netherlands, there are many people with cardiometabolic diseases. More than half of these people also have fatty liver. This is a build-up of fat in the liver (steatosis) and can lead to long-term scarring (fibrosis) and…
- Conditions
- Diabetes Mellitus, Type 2, Liver Fibrosis, Liver Steatoses, Hepatic Steatosis
- Trial name
- MEDFAST (NCT06845345)
- Testing
- early time restricted Mediterranean diet, Mysimba
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Carmen Dietvorst
Obesity
South Danish Obesity Initiative, Screening for Unrecognized Obesity Related Disease
People with BMI >30 kg/m2 will be included in at population-based cohort. Additionally, one control group with BMI 18.5-25 kg/m2 and one control group with BMI 25-30 kg/m2 will be included.
- Trial name
- SDOI (NCT05176132)
- Testing
- Life style intervention (dietician+ physiotherapist), Self management, No intervention
- Where
- Denmark
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- Claus Bogh Juhl