Clinical trials: Gastroscopy
Patients Requiring Diagnostic Gastroscopy With Sedation
A Single-centre Study of Entonox Versus Midazolam Sedation in Gastroscopy
This study aims to determine whether Entonox (gas and air) is at least as good as intravenous midazolam in providing analgesia and sedation during gastroscopy.
- Trial name
- NCT01744184
- Testing
- Entonox, Midazolam
- Where
- United Kingdom
- Volunteers
- 62 people
- Sponsor
- The Royal Bournemouth Hospital
Upper GI Bleeding, Point of Care Ultrasound
Bedside Ultrasonic Assessment for Gastric Content in Patients With Upper GI Bleeding Undergoing Endoscopy
Emerging studies have evaluated POCUS (Point of Care Ultrasound) for assessing of gastric content prior to anesthesia to reduce the risk of aspiration and demonstrated that POCUS can accurately identify presence of gastric food…
- Conditions
- Upper GI Bleeding, Point of Care Ultrasound, Upper Endoscopy, Gastric Content
- Trial name
- NCT05763745
- Testing
- Point of Care Ultrasound
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loma Linda University
Pain
Carbon Dioxide Versus Air Insufflation in Oesophago-gastro-duodenoscopy (OGD)
Comparison on the effect on patient pain and discomfort by using CO2 instead of air for insufflation during gastroscopy.
- Trial name
- NCT00627211
- Testing
- CO2 insufflation
- Volunteers
- 107 people
- Sponsor
- Norwegian Department of Health and Social Affairs
Gastrointestinal Hemorrhage
Video Capsule Endoscopy Versus Colonoscopy in Patients With Melena and Negative Upper Endoscopy
Acute gastrointestinal bleeding is a common medical problem. When patients with gastrointestinal bleeding present with melena (dark, tarry stool) the blood loss is usually originating in the upper gastrointestinal tract…
- Trial name
- NCT02609100
- Testing
- Video Capsule Endoscopy, Colonoscopy, 1.0 X 2.5 cm 'pill' containing a camera
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Washington University School of Medicine
Diagnostic Gastroscopy
Intravenous Lidocaine to Reduce Propofol Consumption During Gastroscopy.
The goal of this clinical trial is to assess if intravenous administration of linisol reduce the propofol consumption and the sides effects of sedation during gastroscopy in healthy patients (ASA 1 and 2 patients).
- Trial name
- NCT05944887
- Testing
- Lidocaine 2% Injectable Solution, Propofol injection, gastroscopy
- Where
- Belgium
- Volunteers
- 46 people
- Sponsor
- Erasme University Hospital
Endoscopy
Fentanyl Use for Sedation in Esophagogastroduodenoscopy
The purpose of this study is to determine whether conscious sedation with a narcotic and sedative (in combination) is as efficacious as a sedative alone for elective upper endoscopy to achieve optimal patient comfort and ease of…
- Trial name
- FUSE (NCT01514695)
- Testing
- Midazolam, Fentanyl
- Where
- Canada
- Volunteers
- 139 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Gastrointestinal Endoscopy
Moderate Sedation Combined With Acupuncture Anesthesia in Gastroscopy and Colonoscopy on Screening Research
The purpose of this study is mainly about the feasibility and rationality of moderate sedation combined with acupuncture anesthesia in the application of gastroscopy and colonoscopy ,Then we evaluate the effectiveness and…
- Trial name
- NCT05485064
- Testing
- fentanyl, eletroacupuncture(transcutaneous electrical acupuncture point stimulation ), remimazolam
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Diagnostic Gastroscopy
Intravenous Lidocaine to Reduce ED50 for Propofol Administered Using Target Controlled Infusion (TCI) During Gastroscopy
The goal of this prospective, interventionnal clinical trial is to assess if intravenous administration of linisol reduce the ED50 of propofol when administered using Target Controlled Infusion (TCI) during gastroscopy in healthy…
- Trial name
- NCT06143410
- Testing
- Lidocaine 2% Injectable Solution, Propofol injection, gastroscopy
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Erasme University Hospital
Barrett's Esophagus, GERD
Study of Endoscopic Barrett's Esophagus Diagnosis
Barrett's esophagus (BE) is a condition that often occurs in patients who have had GERD for a long time. The researchers are interested in BE because it can sometimes become a cancer in the esophagus.
- Trial name
- NCT00591461
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- Oregon Health and Science University
Conscious Sedation, Procedural Sedation
Propofol vs Remifentanil for Sedation in Gastroscopy
This prospective randomized study aims to compare propofol and remifentanil for sedation during elective diagnostic gastroscopy.
- Trial name
- ROPOGAST (NCT07336628)
- Testing
- Propofol (Astra-Zeneca), Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Gastrointestinal Disease
Application of Remimazolam Combined With Esketamine in Painless Gastroscopy and Colonoscopy in Elderly Patients
The objective of this clinical trial is to assess the feasibility of the remimazolam combined with esketamine OFA (opioid-free anesthesia) protocol for painless gastroscopy and colonoscopy in elderly patients and to determine if…
- Trial name
- NCT07002801
- Testing
- remimazolam-remifentanil, remimazolam-esketamine
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Harbin Medical University
Colorectal Polyp
Web-Mediated Risk Assessment for Endoscopic Screening of Colorectal Polyps
Colorectal polyps are risk factors for cancer. Early detection of polyps is critical for colorectal cancer management. However, the diagnosis rate of patients with colorectal polyps is still low.
- Trial name
- NCT03750617
- Testing
- pre-endoscopic screening risk assessment
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- State Key Laboratory of Cancer Biology
Procedural Anxiety, Physiological Stress
Effect of White Noise on Salivary Cortisol and Vital Signs During Gastroscopy
This randomized controlled trial aims to determine whether white noise affects salivary cortisol levels and vital signs in adult patients undergoing gastroscopy.
- Trial name
- NCT07798934
- Testing
- White Noise
- Volunteers
- 100 people
- Sponsor
- Yuzuncu Yil University
HIV Infections, Weight Gain
The Effect Tenofovir Disoproxil Fumarate (TDF) and Tenofovir Alafenamide (TAF) on Small Intestine Gut Wall
Several studies among people living with HIV (PLWH) have shown more weight gain with tenofovir alafenamide (TAF) than with tenofovir disoproxil fumarate (TDF).
- Trial name
- TENENTOX (NCT05326971)
- Testing
- gastroscopy
- Where
- Finland
- Volunteers
- 24 people
- Sponsor
- Jussi Sutinen
Crohn's Disease
The ImageKids Study: Developing the pMEDIC and the PICMI
The overall objectives of this study are to develop two indices capable of measuring intestinal damage, and, separately, inflammatory disease activity in Pediatric Crohn's disease by means of Magnetic Resonance Imaging with…
- Trial name
- NCT01881490
- Testing
- MRE
- Where
- Israel
- Volunteers
- 240 people
- Sponsor
- Shaare Zedek Medical Center
Visualisation and Evaluation of Ampulla of Vater
Cap Assisted Upper Endoscopy to Visualize the Major Duodenal Papilla
Aim of the present study is the evaluation of the diagnostic value of a cap assisted upper GI-endoscopy compared to a standard upper GI-endoscopy regarding the visualisation and evaluation of the papilla duodeni major.
- Trial name
- Kappa-I (NCT02877797)
- Testing
- Cap
- Where
- Germany
- Volunteers
- 101 people
- Sponsor
- Technical University of Munich
Gastric Cancer
Screening for Gastric Cancer in High-risk Population
Introduction: Gastric cancer is the world's second largest cause of cancer related deaths. In the Western world, as well as in Israel, this malignancy is less prevalent than colorectal cancer, but has higher morbidity and…
- Trial name
- Stomach (NCT00815113)
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rabin Medical Center
EGD Procedure
Moderate Sedation for Elective Upper Endoscopy With Balanced Propofol Versus Propofol Alone: a Randomized Clinical Trial
Since introduction in 1989, propofol has gained wide acceptance for sedation during endoscopic procedures. The optimal sedation drug during esophagogastroendoscopy (EGD) is not established.
- Trial name
- NCT02174588
- Testing
- Midazolam + propofol, propofol
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Hypoxemia
Oxygen Delivery Methods of Nasal Catheter on the Incidence of Hypoxemia in Patients With Painless Gastroscopy
In this study, patients undergoing painless gastroscopy were selected to change the nasal catheter oxygen delivery mode to oral oxygen delivery after endoscope implantation, in order to explore the effect of this oxygen delivery…
- Trial name
- NCT06139081
- Testing
- Oxygen delivery mode
- Where
- China
- Volunteers
- 648 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Gastro Esophageal Reflux, Gastric Ulcer
Comparison Between Two Types of Sedation for Elective Upper Endoscopy Procedures
Sedation is defined as the act of administrating a sedative drug to produce a state of calm or sleep. Sedation is commonly given to a patient in hospital settings to provide a tolerable and pleasant experience by relieving…
- Conditions
- Gastro Esophageal Reflux, Gastric Ulcer, Sedation Complication
- Trial name
- NCT04410211
- Testing
- Sevoflurane, Midazolam injection
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya