Clinical trials: Gays
Sexual Behavior
Young Men and Media Study
Adolescent sexual minority males (ASMM) continue to account for a disproportionate number of HIV infections in the United States. Racial and ethnic minority populations are particularly affected.
- Trial name
- NCT04109443
- Testing
- Young Men & Media Program, Available websites on safe sex and preventing STIs
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Boston University
Hiv, HIV/AIDS
AllyQuest Adherence App Intervention for HIV-positive Men Who Have Sex With Men and Transgender Women: Pilot Trial
AllyQuest (AQ) is a theory-informed smart phone application that supports HIV medication adherence for young men who have sex with men and young transgender women who have sex with men (YMSM/YTW) via behavior change, social…
- Conditions
- Hiv, HIV/AIDS, Medication Adherence, Sexual Behavior
- Trial name
- AQ2 (NCT03916484)
- Testing
- AllyQuest HIV Medication Adherence app-delivered intervention, AllyQuest HIV Medication Adherence app-delivered intervention + NSC
- Where
- 6 sites in United States
- Volunteers
- 71 people
- Sponsor
- University of North Carolina, Chapel Hill
Amphetamine-Related Disorders, HIV
Contingency Management for Methamphetamine Abstinence and HIV Post-Exposure Prophylaxis in Men Who Have Sex With Men
This study seeks to decrease methamphetamine use and concomitant high-risk sexual behaviors among methamphetamine-using men who have sex with men (MSM) by combining a biomedical intervention with a behavioral intervention.
- Conditions
- Amphetamine-Related Disorders, HIV, HIV Infections
- Trial name
- NCT00856323
- Testing
- Truvada, CM
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Friends Research Institute, Inc.
Methamphetamine Abuse, HIV/AIDS
The Getting Off App for Methamphetamine-Using Gay and Bisexual Men
A commonly used manualized outpatient methamphetamine intervention for gay and bisexual men, "Getting Off," is being translated into a mobile phone application (i.e., app) available for download through common app marketplaces.
- Trial name
- NCT03884946
- Testing
- Getting Off App
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Friends Research Institute, Inc.
HIV
Harnessing the Power of Text Messaging to Invigorate AMSM HIV Preventive Behavior
The purpose of this study is to examine whether Guy2Guy (G2G), a text messaging-based healthy sexuality and human immunodeficiency virus (HIV) prevention program intervention for 14-18 year gay, bisexual and queer men, is…
- Trial name
- G2G (NCT02113956)
- Testing
- Guy2Guy (G2G)
- Where
- 2 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research
HIV
Home Self-Testing for HIV to Increase HIV Testing Frequency in Men Who Have Sex With Men (The iTest Study)
The purpose of this study is to determine whether the availability of home self-testing for HIV will increase HIV testing frequency among men who have sex with men without negatively impacting their risk for HIV acquisition.
- Trial name
- NCT01161446
- Testing
- Home HIV self-testing with OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Washington
Smoking Cessation
SmokefreeSGM, A Text-based Smoking Cessation Feasibility Trial for Sexual and Gender Minority Groups
The purpose of this study is to test the feasibility and acceptability of Smokefree Sexual and Gender Minority (SGM), an SGM-tailored version of the SmokefreeTXT text messaging program
- Trial name
- NCT05645354
- Testing
- SmokefreeSGM, SmokefreeTXT
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
HIV Infections
The SOLVE-IT National Randomized Trial
This study will evaluate the effectiveness of an interactive virtual environment computer game in reducing risky sexual behaviors among men who have sex with men.
- Trial name
- SOLVE-IT (NCT00653991)
- Testing
- SOLVE-IT
- Where
- United States
- Volunteers
- 2,020 people
- Sponsor
- University of Southern California
HIV Infection
Evaluating the Safety and Tolerability of Antiretroviral Drug Regimens Used as Pre-Exposure Prophylaxis to Prevent HIV Infection in At-Risk Men Who Have Sex With Men and in At-Risk Women
Pre-exposure prophylaxis (PrEP) is a method of preventing HIV infection through the use of antiretroviral (ARV) medications before exposure to HIV.
- Trial name
- NCT01505114
- Testing
- Maraviroc, Emtricitabine, Tenofovir disoproxil fumarate
- Where
- 13 sites in United States, Puerto Rico
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV
PrEP, Lube, and the Rectal Mucosa in MSM at Risk of HIV
The purpose of this study is to determine whether the use of rectal lubricants can affect how well the medication, Truvada, will work to prevent infection with HIV when someone is exposed to HIV in the rectum.
- Trial name
- NCT02401230
- Testing
- Truvada, Gel lubricant
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Emory University
Pre-exposure Prophylaxis
Electronic Pre-exposure Prophylaxis (PrEP) Initiation and Maintenance Home Care System
The premise for the study is that a tailored approach for rural young men who have sex with men (YMSM), addressing known barriers of transportation, access to providers, and privacy, is most likely to yield high levels of…
- Trial name
- ePrEP (NCT03729570)
- Testing
- ePrEP
- Where
- 4 sites in United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV, Pre-exposure Prophylaxis
The Development of a Mobile-based App to Increase Uptake of Pre-Exposure Prophylaxis (PrEP) by Men Who Have Sex With Men in China
This study aims to use a mini-application on the popular Chinese social media mobile platform, WeChat, to improve HIV pre-exposure prophylaxis (PrEP) uptake among at-risk men who have sex with men (MSM).
- Trial name
- NCT04426656
- Testing
- Phone application
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections
eTest: Real-time, Remote Monitoring System for Home-based HIV Testing Among High-risk Men Who Have Sex With Men
The proposed research will conduct a fully-powered efficacy trial of this approach in areas with large populations of AA and H/L MSM and high HIV incidence: Jackson, MS, Los Angeles, CA, and Boston, MA.
- Trial name
- eTest (NCT03654690)
- Testing
- HIV self-test, Counseling
- Where
- United States
- Volunteers
- 811 people, healthy volunteers welcome
- Sponsor
- Brown University
Human Immunodeficiency Virus
Mobile-health (mHealth) Intervention to Support HIV Self-testing and PrEP Uptake Among Young Men Who Have Sex With Men
The proposed study will involve adolescent (17-24 years old) men who have sex with men (described as YMSM hereafter) who meet eligibility criteria to participate.
- Trial name
- NCT04865341
- Testing
- IMB, Information-Only Control
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Syphilis
Syphilis Self-testing to Expand Test Uptake Among Men Who Have Sex With Men (SST)
Syphilis infection is a major global health problem, leading to substantial morbidity among key populations in low- and middle-income countries (LMICs).
- Trial name
- NCT04480749
- Testing
- Access to Facility based Syphilis Testing, Syphilis Self-Test
- Where
- Zimbabwe
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
HIV
A Pilot Intervention to Improve Coping With Discrimination and Adherence Among HIV-Positive Latino MSM
R34-funded study to pilot test an intervention to improve coping with discrimination and adherence among Latino men who have sex with men (MSM) living with HIV.
- Trial name
- NCT03432819
- Testing
- Siempre Seguiré
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- RAND
Harm Reduction
Harm Reduction Strategies for Gay, Bisexual and Other Men Who Have Sex With Men Engaging in Chemsex
This study is examining the usability and effectiveness of an innovative mobile app that integrates harm reduction strategies into the existing pre-exposure prophylaxis (PrEP) intake and adherence app, with an overarching goal to…
- Trial name
- NCT06187415
- Testing
- Mobile app to reduce harm of chemsex
- Where
- Taiwan
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
HIV Infection
Evaluation of Rapid HIV Self-testing Among MSM (eSTAMP)
This study seeks to determine the public health impact of providing rapid HIV test kits to men who have sex with men (MSM) so they may test themselves at their convenience.
- Trial name
- NCT02067039
- Testing
- OraQuick in home & Sure Check HIV tests
- Where
- United States
- Volunteers
- 2,665 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV, Gonorrhea
Keep It Up! 2.0: A Comparison of Two Online HIV Intervention Programs for Young Men Who Have Sex With Men
Young men who have sex with men (YMSM) account for almost 70% of HIV diagnoses among all young people in the U.S. and are alone in facing an increasing rate of infections.
- Conditions
- HIV, Gonorrhea, Chlamydia
- Trial name
- KIU! (NCT01836445)
- Testing
- Keep It Up!, HIV Knowledge Control
- Where
- 3 sites in United States
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Anal Chlamydia Infection
Trial of Azithromycin vs. Doxycycline for the Treatment of Rectal Chlamydia in MSM
A clinical trial to compare the efficacy of azithromycin (Arm 1) vs. doxycycline (Arm 2) administered per CDC's STD Treatment Guidelines for rectal Chlamydia trachomatis (CT) in men who have sex with men (MSM).
- Trial name
- NCT03608774
- Testing
- Azithromycin, Doxycycline
- Where
- 2 sites in United States
- Volunteers
- 177 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)