Clinical trials: Gender Differences
Cerebrovascular Disorders
Brain Blood Flow Responses to Stress: Sex Differences
Twenty-six otherwise healthy adults between 18-40 years of age composed of 13 males and 13 females will be enrolled in this study to determine how sex and sex hormones influence cerebral blood flow (CBF) control in healthy young…
- Trial name
- NCT06253702
- Testing
- Indomethacin, Orilissa, Testosterone gel
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Circadian Misalignment, Sex Differences
Does Circadian Misalignment Have Sex-Specific Effects on Metabolism?
This study will test whether biological sex influences how the body responds to circadian misalignment-a mismatch between the internal body clock and the timing of sleep and eating (as can occur with shift work or jet lag).
- Trial name
- NCT07441265
- Testing
- Day shift, Night shift
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Gender Identity
Sexual Dimorphism Analysis in Egyptian Population by Locating the Mandibular Canal Using CBCT
Sexual dimorphism analysis in Egyptian population by locating the mandibular canal using cone-beam computed tomography: an observational cross sectional study
- Trial name
- NCT03175445
- Testing
- CBCT scan by planmeca promax
- Where
- Egypt
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sex, Gastrointestinal Cancers
Sex Differences in Gastrointestinal Cancer Surgery
This study aims to investigate whether there are differences in surgical outcomes between male and female patients with gastrointestinal cancers (esophagus, colon, rectum, stomach, or pancreas).
- Conditions
- Sex, Gastrointestinal Cancers, Surgical Resection, Sex Differences
- Trial name
- SeDiGCS (NCT07017712)
- Testing
- Complex esophageal surgery for carcinoma, Rectum resection for carcinoma, Colon resection for carcinoma
- Volunteers
- 870,754 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Hyponatremia
Postoperative Hyponatremia - Are There Gender Differences?
The proposed study will focus on anesthesia and anesthesia-induced hypotension as a possible cause for postoperative fluid retention and hyponatremia, and investigate gender differences in this response.
- Trial name
- NCT00636857
- Testing
- Fluid administration, Perioperative fluid management based on Lean Body Mass
- Where
- 5 sites in Sweden
- Volunteers
- 60 people
- Sponsor
- Karolinska University Hospital
Heart Failure With Preserved Ejection Fraction
Study to Evaluate Sex Differences in the Acute Effects of PL-3994 in Heart Failure Subjects
A Multi-Center, Unblinded, Single-Arm Study to Evaluate Sex Differences in the Acute Effects of PL-3994 on Myocardial cGMP Enhancement and Hemodynamics in Heart Failure with Preserved Ejection Fraction
- Trial name
- NCT04318145
- Testing
- PL-3994 Aqueous Intravenous Solution Dose Ascention, PL-3994 Aqueous Intravenous Solution Single Dose
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Palatin Technologies, Inc
Left Sided Heart Failure
Effect of Left Ventricle Diastolic Dysfunction on Outcomes in Female Cardiac Surgery Patients
The aim of this study is to evaluate the differences between males and females with LVDD, undergoing cardiac surgery. The investigators will look at perioperative factors such as body weight, body surface area, previous medical…
- Trial name
- EDISON (NCT05972356)
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
type1diabetes
Sexual Dimorphism in Cardiovascular Autonomic Neuropathy in Patients With Type 1 Diabetes
Sex might interact with cardioautonomic neuropathy (CAN) in the development of macrovascular disease in patients with type 1 diabetes (T1D).
- Trial name
- NCT04950634
- Where
- Spain
- Volunteers
- 320 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Gender Discrimination, Cardiac Event
AN OBSERVATIONAL STUDY ON CARDIOVASCULAR INVOLVEMENT IN COVID RECOVERED PATIENTS
Aim of the study is to evaluate the prevalence and bring awareness ofcardiovascular complications in COVID-19 recovered patients.
- Conditions
- Gender Discrimination, Cardiac Event, Complication
- Trial name
- NCT05710796
- Testing
- Difference in gender, response to disease, diagnostic test values
- Where
- India
- Volunteers
- 500 people
- Sponsor
- Kakatiya University
Cocaine Dependence
Gender Differences in Response to Cues in Cocaine Dependence
The purpose of this study is to evaluate whether men and women respond differently to seeing items related to cocaine use or to remembering stressful events.
- Trial name
- NCT00969943
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Marijuana Dependence
Hormones and Reduction in Co-users of Marijuana and Nicotine
The purpose of this study is to examine the role of progesterone (a naturally occurring hormone found in both men and women) on reducing marijuana use.
- Trial name
- NCT02579421
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
PTSD
Sex/Gender Differences in Risk and Resilience to PTSD; Implication of Oxytocin
The purpose of the study is to use fMRI to investigate amygdala response to fearful faces in men and women with and without PTSD who have experienced childhood trauma.
- Trial name
- NCT01963078
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Megan Moran-Santa Maria
65 Years Older, CHF - Congestive Heart Failure
ChatGPT -Based Intervention for Social Frailty in Older Women With CHF : Gender Differences
The study is planned to be completed over three years and will focus on 500 hospitalized older adults with a diagnosis of CHF. The Biopsychosocial model will be used to conduct this study.
- Conditions
- 65 Years Older, CHF - Congestive Heart Failure, Social Communication
- Trial name
- NCT07091435
- Testing
- ChatGPT, community social
- Volunteers
- 500 people
- Sponsor
- Chang Gung University of Science and Technology
Schizophrenia
Sex Differences in NMDA-enhancing Treatment of Schizophrenia
Schizophrenia differs between sexes in clinical symptoms and functional outcome. Negative symptoms are the core pathology of this disease. NMDA receptor (NMDAR) dysfunction is a key factor in negative symptoms.
- Trial name
- NCT07122895
- Testing
- NMDAE
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- China Medical University Hospital
Cardiovascular
The Role of EDHFs on Blood Pressure Following a Bout of Prolonged Sitting
Canadians spend most of their day in sedentary postures (i.e., sitting, lying, reclining). While the beneficial impacts of physical activity on the heart are well-established, less is known about the consequences during time…
- Trial name
- NCT07396857
- Testing
- Fluconazole 150 mg
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Post Acute COVID-19 Syndrome
Gender Differences in the Recovery Rate Following PR in Patients With Long COVID-19
The goal of this retrospective analysis is to compare the magnitude of improvement in respiratory and peripheral muscle strength, following the completion of a hybrid pulmonary rehabilitation programme, in men and women with long…
- Trial name
- NCT05736939
- Testing
- Out-patient Pulmonary Rehabilitation
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- National and Kapodistrian University of Athens
Overweight, Obesity
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study
The purpose of this study is to determine whether the combination of two dietary supplements: MUSCLE 5, which contains protein, creatine and vitamin D and TRIM 7, which contains beet extract, caffeine, coenzyme Q10, alpha lipoic…
- Trial name
- NCT05384431
- Testing
- Muscle5 and TRIM7, Mixed exercise
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Exerkine Corporation
Position Sense, Sex Characteristics
Shoulder Proprioception: a Comparative Study on Hand Dominance and Sex
The goal of this cross-sectional study is to examine the differences in proprioception sensation depending on sex and dominant side factors in healthy volunteers.
- Conditions
- Position Sense, Sex Characteristics, Glenohumeral Joint, Upper Extremity
- Trial name
- NCT06602427
- Testing
- Shoulder proprioception measurement using isokinetic dynamometer
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gender Role Disorder, Male to Female Type
Gender-specific aEEGs and Outcome in Preterms
Background and objectives: Male sex is a risk factor for poor neurodevelopmental outcome following preterm birth. The investigators aimed to investigate gender-related differences in amplitude-integrated electroencephalography…
- Trial name
- NCT01562236
- Where
- Austria
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pacemaker, Artificial, Cohort Studies
Morbidity, Mortality and Gender Differences in Patients With Pacemakers
Previous publications suggest gender difference in outcome parameters after pacemaker implantation. Aim of this study is to investigate gender differences in patients with pacemaker.
- Conditions
- Pacemaker, Artificial, Cohort Studies, Arrhythmias Requiring Therapy, Cardiac Pacing, Artificial
- Trial name
- NCT03388281
- Testing
- No intervention, retrospective analysis only.
- Volunteers
- 11,444 people
- Sponsor
- Medical University of Vienna