Clinical trials: Gender Differences
Fasting, Obesity (BMI>30)
The Effect of Fasting on Peak Fat Oxidation, Mitochondrial Coupling and Extracellular Matrix
The interventional study will recruit four groups (n=10 per group): Young men and women with normal weight (BMI 18-25), and young men and women with obesity (BMI >30).
- Conditions
- Fasting, Obesity (BMI>30), Sex Difference
- Trial name
- GlycoFast84 (NCT07692646)
- Testing
- Diet
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Heart Failure With Preserved Ejection Fraction, Diastolic Dysfunction
Sex Related Differences in Cardiac Function
The aim of the study is to investigate sex-specific differences in LV and RV function (systolic and diastolic) with regarding the development and progression of heart failure with preserved ejection fraction based on a…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Diastolic Dysfunction, Systolic Dysfunction
- Trial name
- NCT05796050
- Where
- Germany
- Volunteers
- 6,000 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Cannabis
Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study I
The purpose of the study is to characterize the acute effects of cannabinoids in women relative to men and to begin probing the mechanisms that may underlie gender differences.
- Trial name
- THC-Gender-I (NCT02811510)
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Cardiovascular Disease
Sex Differences in Oral Bacteria
Females have a lower incidence of hypertensive and cardiovascular disorders that may relate to differences in nitrogen oxides in the blood and saliva.
- Trial name
- NCT01583803
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Overweight, Obesity
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study
The purpose of this study is to determine whether the combination of two dietary supplements: MUSCLE 5, which contains protein, creatine and vitamin D and TRIM 7, which contains beet extract, caffeine, coenzyme Q10, alpha lipoic…
- Trial name
- NCT05384431
- Testing
- Muscle5 and TRIM7, Mixed exercise
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Exerkine Corporation
Cerebrovascular Disorders
Brain Blood Flow Responses to Stress: Sex Differences
Twenty-six otherwise healthy adults between 18-40 years of age composed of 13 males and 13 females will be enrolled in this study to determine how sex and sex hormones influence cerebral blood flow (CBF) control in healthy young…
- Trial name
- NCT06253702
- Testing
- Indomethacin, Orilissa, Testosterone gel
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Allergic Asthma, Asthma
Gender Differences and SNPs in Asthmatic Patients
The GINA 2020 guidelines suggest that asthma affects approximately 300 million persons worldwide. Even if there is a specific drug treatment for each stage of disease (From mild to severe) in some patients it is not efficacy and…
- Trial name
- NCT04567212
- Testing
- genetic evaluation, MicroRNA evaluation
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Catanzaro
65 Years Older, CHF - Congestive Heart Failure
ChatGPT -Based Intervention for Social Frailty in Older Women With CHF : Gender Differences
The study is planned to be completed over three years and will focus on 500 hospitalized older adults with a diagnosis of CHF. The Biopsychosocial model will be used to conduct this study.
- Conditions
- 65 Years Older, CHF - Congestive Heart Failure, Social Communication
- Trial name
- NCT07091435
- Testing
- ChatGPT, community social
- Volunteers
- 500 people
- Sponsor
- Chang Gung University of Science and Technology
Non-small Cell Lung Cancer
Evaluation of Gender Differences on the Psychosocial and Economic Impact in Patients With Advanced Non-small Cell Lung Cancer
The purpose of this study is to evaluate of gender differences on the psychosocial and economic impact in patients with advanced non-small cell lung cancer.
- Trial name
- IMPULSO (NCT02336061)
- Testing
- Evaluation of gender differences on the psychosocial and economic impact.
- Where
- 18 sites in Spain
- Volunteers
- 344 people
- Sponsor
- Asociación para la Investigación del Cáncer de Pulmón en Mujeres
Obesity, Diabetes
"ISIS" Study of Sex Differences in Characteristics of Adiposity and Metabolism
The purpose of this study is to characterize differences in the structure and function of the body fat from two different parts of the body in young, healthy men and women.
- Trial name
- ISIS (NCT00704197)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Chronic Renal Failure, Healthy Controls
Gender Differences in Renal Functioning and Disease
The purpose of the GenderBOLD study is to shed light on the mechanisms responsible for women's lower susceptibility to developing and progressing chronic renal disease, using modern imaging techniques, and applying different…
- Trial name
- GenderBOLD (NCT04085094)
- Testing
- high-salt diet (V1) and low salt diet (V2), Contrast-enhanced ultrasound (CEUS), functional MRI
- Where
- Switzerland
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
ASPIRATION
The Cricoid Force Necessary to Occlude the Esophageal Entrance: Is There a Gender Difference?
the investigators have observed that women may require less CF than men to occlude the esophageal entrance, and that the routine use of 30 N in women may actually increase the incidence of airway-related problems.
- Trial name
- NCT02618863
- Testing
- Cricoid pressure
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Procare Riaya Hospital
Platelet Aggregation
Study to Determine Racial and Gender Differences in Platelet Aggregation
The purpose of this study is to see if there is a racial and/or gender difference in platelet aggregation.
- Trial name
- NCT00233428
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Gastric (Stomach) Cancer, Sex Difference
Epidemiology and Treatment of Gastric Cancer
According to recent statistics, the incidence and mortality from gastric cancer are both worldwide in fifth place in terms of ranking. Gastric cancer is more common in males than in females.
- Trial name
- NCT07213115
- Testing
- Gastrectomy+ chemotherapy
- Volunteers
- 8,582 people
- Sponsor
- Medizinische Hochschule Brandenburg Theodor Fontane
Ultra-marathon Runners
Fatigability Compared Men and Women Induced According to the Distance Traveled on an Ultra-marathon in the Mountains
Acute physiological consequences of ultra-marathon running are still unknown, particularly in women. Some studies have suggested that the proportion of fatigue attributable to peripheral and central mechanisms varies between…
- Trial name
- UTMB_2019 (NCT04025138)
- Testing
- Neuromuscular tests in isometric mode, Transcranial Magnetic Stimulation (TMS), Neuromuscular fatigue assessment test
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Professional Role, Physical Activity
Are Women With Higher Professional Status More Sedentary Compared to Men?
It is aimed to understand the gender differences on factors affecting the resting metabolic rate of people in different professional status.
- Conditions
- Professional Role, Physical Activity, Obesity, Education
- Trial name
- NCT03587233
- Testing
- Physical assessment, Analyses of body composition, physical activity level assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istinye University
Anesthesia
Effect of Gender on Propofol Requirement
Total intravenous anaesthesia (TIVA) has emerged as a viable alternative to inhalational general anaesthesia (GA). Propofol is the preferred drug for providing TIVA due to its favorable pharmacokinetic profile, such as, rapid…
- Trial name
- NCT05725135
- Testing
- Propofol
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Sir Ganga Ram Hospital
Turner Syndrome, Post-menarcheal Adolescents
Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy
Background: Turner Syndrome, galactosemia, and premature ovarian insufficiency are all conditions that may make it very hard or impossible for a person to become pregnant and have their own child.
- Conditions
- Turner Syndrome, Post-menarcheal Adolescents, Ovarian Disfunction, Galactosemia
- Trial name
- NCT04948658
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Inactivity, Physical, Aging
Oral 'Breath Test' to Measure Anabolic Sensitivity to a Protein Meal Across the Age and Physical Activity Spectrum
The purpose of this study is to determine how anabolic sensitivity, in response to the ingestion of a liquid protein meal, differs across the lifespan, between biological sexes, and with varying physical activity levels.
- Conditions
- Inactivity, Physical, Aging, Healthy Aging, Growth & Development
- Trial name
- NFRF (NCT06744491)
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypertrophy, Body Weight Changes
Examining Changes in Muscle Size and Body Composition Between Two Hypertrophy Resistance Training Programs in Males
This study aims to investigate if a less physically and psychologically taxing approach to resistance training can generate equal or greater outcomes when compared to a more physically and psychologically taxing approach.
- Conditions
- Hypertrophy, Body Weight Changes, Muscle Size
- Trial name
- NCT05667233
- Testing
- Resistance Training Program
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Dalhousie University