Clinical trials: Gender Related Stress
LGBTQ, Racial Disparities
Family Acceptance Project Online (Pilot RCT)
Research shows that sexual and gender minority youth (SGMY) experience high rates of mental health problems and other challenges (e.g., social, academic).
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- FAP-O (NCT06839859)
- Testing
- Family Acceptance Project - Online
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Depression, Posttraumatic Stress Disorder
Randomized Controlled Trial of Interpersonal Psychotherapy for Depression and PTSD Among HIV+ Women in Kenya
The aim of this study is to conduct a 12-week IPT+TAU versus wait list TAU in a cohort of HIV+GBV+ women in Nyanza Province to relieve depression and PTSD and improve ARV adherence.
- Conditions
- Depression, Posttraumatic Stress Disorder, HIV
- Trial name
- NCT02320799
- Testing
- interpersonal psychotherapy, treatment as usual
- Where
- Kenya
- Volunteers
- 300 people
- Sponsor
- University of California, San Francisco
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Occupational Stress, Gender Related Stress
Sisters for Heart Health: A Community Health Worker Initiative for Improving Heart Health in Farmworker Women
The goal of this hybrid Type 1 effectiveness-implementation trial is to test the extent to which a peer support and community resource navigation intervention improves psychological well-being, addresses non-biologic drivers of…
- Conditions
- Occupational Stress, Gender Related Stress, Social Isolation, Hypertension
- Trial name
- NCT07111026
- Testing
- Sisters for Heart Health, Basic intervention
- Where
- United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Emory University
Stress, Early Life Stress
How Does the Opioid System Shape Stress and Social Behaviour in Men and Women and What Role Does Childhood Unpredictability Play?
The study aims to investigate sex differences in the effect of mu-opioid receptor (MOR) activation on stress response and social behaviour modulated by early life stress.
- Conditions
- Stress, Early Life Stress, Sex Differences, Opioid
- Trial name
- MOR-SAFE (NCT07778511)
- Testing
- Morphine
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sara L. Kroll
Sexual Risk Behavior, Childhood Sexual Abuse
HIV Prevention and Trauma Treatment for Men Who Have Sex With Men With Childhood Sexual Abuse Histories
Brief Summary: The specific aims of this study are: 1. To test, in a two-arm randomized controlled trial, the efficacy of cognitive processing therapy for sexual risk and posttraumatic symptom severity reduction (CPT-SR) in…
- Conditions
- Sexual Risk Behavior, Childhood Sexual Abuse, Stress Disorders, Post-Traumatic
- Trial name
- THRIVE (NCT01395979)
- Testing
- Cognitive Processing Therapy for Sexual Risk, Supportive Psychotherapy, Sexual Risk Reduction Intervention
- Where
- 3 sites in United States
- Volunteers
- 232 people
- Sponsor
- Massachusetts General Hospital
Sexual and Gender Minorities, Pregnancy Complications
Physical and Mental Health Among Sexual and Gender Minorities During Pregnancy, Birth and Postpartum
Mental illness increases the risk of adverse birth outcomes (e.g. preterm birth), obstetric complications (e.g. emergency caesarean, birth injuries), and birth trauma.
- Conditions
- Sexual and Gender Minorities, Pregnancy Complications, Obstetric Complication, Psychological Trauma
- Trial name
- NCT05354284
- Testing
- online questionnaire
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Social Isolation or Loneliness, Anxiety
Health Surveillance at Constructor University Bremen (CUB)
The aim of Health Surveillance is to analyze and describe the state of health of students at Constructor University, key influencing factors and individual resources by using mixed-method design.
- Conditions
- Social Isolation or Loneliness, Anxiety, Anxiety Depression (Mild or Not Persistent), Health Behavior
- Trial name
- CUB-HS2025 (NCT06899308)
- Testing
- questionnaire
- Where
- 2 sites in Germany
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Sexual Assault and Rape, Risk Behavior
Piloting ProHealth: A Program for Male Soldiers on Sex, Dating and Alcohol-Use at Fort Bragg
The proposed project will provide data concerning dating and sexual interactions that occur on Fort Bragg, North Carolina, in addition to piloting a sexual assault prevention program through the use of social norms and bystander…
- Conditions
- Sexual Assault and Rape, Risk Behavior, Alcohol Abuse
- Trial name
- NCT03184298
- Testing
- Surveys, Interviews, Group Discussions
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Womack Army Medical Center
Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases
NightWare and Cardiovascular Health in Veterans With PTSD
The purpose of this study is to learn more about the effectiveness of a prescription wrist-wearable device called NightWare (NW) on improving sleep in Veterans with nightmares related to posttraumatic stress disorder (PTSD).
- Conditions
- Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness
- Trial name
- NCT06419959
- Testing
- NightWare
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sex Trafficking, Sexual Violence
Music Workshops in the EMPOWER Clinic
Women will be recruited from the EMPOWER clinic when they present for care; they may be given a flyer as part of their clinic entry paperwork, or approached by a study staff member in the waiting area of the clinic.
- Conditions
- Sex Trafficking, Sexual Violence, Trauma
- Trial name
- NCT02897505
- Testing
- Music Workshop
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cocaine Dependence
Gender and Neural Substrates of Stress and Craving
Cocaine dependence is an insidious disease underscored by a powerful proclivity to relapse despite an individual's ability to recognize the deleterious consequences of continued drug use.
- Trial name
- NCT00756925
- Testing
- Acthrel
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Medical University of South Carolina
Trauma, Psychological, Traumatic Stress Disorder
Group Cognitive Processing Therapy for Women Survivors of Gender-Based Violence: Feasibility Study
Introduction: Post-traumatic stress disorder (PTSD) is a global health challenge requiring effective, evidence-based interventions, such as Cognitive Processing Therapy (CPT).
- Trial name
- HEALING-TRAUMA (NCT07897903)
- Testing
- Group CPT + TAU (Experimental)
- Volunteers
- 10 people
- Sponsor
- Universidad Complutense de Madrid
Perimenopause, Perimenopause-Related Depression
Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This observational study examines the safety and effects of injecting Muse cells (a type of naturally occurring stem like cells found in adult tissues such as fat or bone marrow) directly into the ovaries of women aged 28 to 70…
- Conditions
- Perimenopause, Perimenopause-Related Depression, Premature Ovarian Insufficiency, Premature Ovarian Failure (POF)
- Trial name
- MUSE-OVARY (NCT07511660)
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Cannabis Use Disorder
SCORE Emerging Adult Cannabis Use & Stress
The interface between cannabis use and stress is a particularly important focus for sex differences research in emerging adults.
- Trial name
- NCT05885542
- Testing
- Cannabidiol oral solution
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Medical University of South Carolina
Alcohol Use Disorder
Guanfacine for Alcohol Use Disorder (AUD)
The investigators assess whether guanfacine extended release (GXR; 3mg/d) compared with placebo (PBO) will attenuate drinking and drinking-related factors in N=200 men and women with Alcohol Use Disorder (AUD) across 12-weeks.
- Trial name
- NCT06629259
- Testing
- Guanfacine Extended Release (XR)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Domestic Violence, Psychological Distress
GBV, Primary Trauma & Trauma Resilience & Understanding Self-help Therapy Utilization in Uganda
The goal of this community-based interventional study was to determine the effectiveness of the 'Trauma Resilience \& Understanding Self-help Therapy' (TRUST) in managing domestic violence \& primary trauma among formerly…
- Conditions
- Domestic Violence, Psychological Distress, Post-Traumatic Stress Disorder, Suicidality
- Trial name
- GBV (NCT06073964)
- Testing
- Trauma Resilience & Understanding Self-help Therapy
- Where
- Uganda
- Volunteers
- 284 people
- Sponsor
- Kampala International University
Adolescent Depression
Adolescent Mood During Puberty and Testosterone
Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention…
- Trial name
- AMPT (NCT06072677)
- Testing
- Healthy Minds Program
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Stress Disorders, Post-Traumatic, Drinking Heavy
Project QueST 2023: Queer Survivors of Trauma
This study aims to test the initial efficacy of tailored online writing interventions specifically designed for sexual minority women, transgender individuals, and/or nonbinary people to target the primary outcomes: posttraumatic…
- Trial name
- QueST2023 (NCT05569915)
- Testing
- Trauma Expressive Writing, Stigma Expressive Writing, Control
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Syracuse University
PostTraumatic Stress Disorder
Effectiveness of Basic Body Awareness Therapy in Post-traumatic Stress Disorders: A Randomized Clinical Trial
The aim of this randomized controlled clinical trial is to assess the effectiveness of Basic Body Awareness Therapy online in patients' survivors of Covid-19, health workers and women suffering from gender based violence…
- Trial name
- BATEP (NCT04396314)
- Testing
- Basic Body Awareness Therapy, Psychological treatment
- Volunteers
- 54 people
- Sponsor
- Universitat de Lleida