Clinical trials: General Anesthesia; Tracheal Intubation
Hemodynamics After Endotracheal Intubation
Preoperative Topical Lidocaine Versus Intravenous Fentanyl to Obtund the Stress of Intubation Under Anesthesia.
To compare the effectiveness of preoperative combined topical airway anesthesia consisting of nebulised, mouth rinsing and gargling with lidocaine versus intravenous fentanyl to prevent the stress of endotracheal intubation by…
- Trial name
- NCT07533643
- Testing
- topical lidocaine, Fentanyl (Low Dose)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Sore Throat, Cough
Comparing the Efficacy Between Lignocaine Given Via MADgic Atomizer and Lignocaine Pump Spray
Comparing the efficacy between Lignocaine given via MADgic Atomizer and Lignocaine Pump Spray pre endotracheal intubation in adult undergoing General Anesthesia.
- Conditions
- Sore Throat, Cough, Hoarseness, Hemodynamic Instability
- Trial name
- NCT06213116
- Testing
- MADgic Atomizer, Lignocaine pump spray
- Where
- Malaysia
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Sore-throat
Incidence of Postoperative Sore-throat Incidence
Postoperative sore throat is a distressing but frequent symptom presented by the patients on the floor upon awakening from General Anesthesia, where endotracheal intubation is part of the Anesthetic protocol.
- Trial name
- InciPost (NCT05354154)
- Testing
- endotracheal intubation
- Where
- Pakistan
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
The Upper Esophageal Sphincter Contraction Strength
ERAS Swallowing Rehabilitation in Elder Patients
The investigators studied that swallowing function of patients receiving the Early Recovery Accelerated Swallowing (ERAS-W program) training will recover fast than that of patients in the control group.
- Trial name
- NCT05999786
- Testing
- early rehabiliation swallowing program, not receiving early rehabilitation swallowing program
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
General Anesthesia
Comparison of the Effects of Dexmedetomidine and Lidocaine on Blood Pressure and Heart Rate Response
Endotracheal intubation is considered a definitive therapy and the gold standard for airway management. However, this procedure carries several risks, including sudden increases in blood pressure and heart rate.
- Trial name
- NCT06573957
- Testing
- Dexmedetomidine, Lidocain
- Where
- Indonesia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Anesthesia, General
The Effects of Dexmedetomidine and Tracheal Intubation on Heart Rate Variability and QTc Interval
The purpose of this study is to investigate effect of dexmedetomidine and tracheal intubation on heart rate variability and QTc interval.
- Trial name
- NCT01584570
- Testing
- 0.5 mcg/kg IV infusion for 10 min, 1.0 mcg/kg IV infusion for 10 min
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Postoperative Sore Throat, Postoperative Cough
Effect of Lidocaine 1% and 2% in the Tube Cuff on Postoperative Sore Throat and Cough
Comparing the effect of different methods of endotracheal tube cuff inflation on the occurrence of a postoperative sore throat and cough (Air vs Lidocaine 1% vs Lidocaine 2%).
- Trial name
- ELIT (NCT03792776)
- Testing
- cuff inflation with air, cuff inflation with lidocaine 1%, cuff inflation with lidocaine 2%
- Volunteers
- 150 people
- Sponsor
- Ogarite Habib
Healthy
The Efficacy and Safety of Gantacurium Chloride for Injection in Tracheal Intubation in Healthy Adult Patients Undergoing Surgery Under General Anesthesia
This is a multicenter, randomized, controlled, observer-blinded, dose-response study to evaluate the efficacy in tracheal intubation and safety of gantacurium chloride for injection in healthy adult patients undergoing surgery…
- Trial name
- NCT00235976
- Testing
- Gantacurium Chloride for Injection (AV430A)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Avera Pharmaceuticals
Perioperative Respiratory Adverse Events, Airway Management
Airway Management and Weight in Children
The investigators in this study want to see how overweight/obese children who undergo elective surgery requiring airway management react to general anesthesia.
- Trial name
- NCT03996343
- Testing
- Endotracheal intubation, Laryngeal mask airway
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
General Anesthesia
Comparison of a Single Use (Ambu aScope) and a Reusable Flexible Optical Scope for Intubation Through a Supraglottic Airway Device (Aura-i)
In patient who are predicted to be difficult to intubate with a standard direct laryngoscope well use flexible optical intubation via a supraglottic airway devise (the Ambu Aura-i).
- Trial name
- NCT02002364
- Testing
- tracheal intubation
- Where
- 2 sites in Denmark, France
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neuromuscular Blockade
Safety and Efficacy of HRS-9190 Compared to Rocuronium for Tracheal Intubation in Adults
The study will enroll adult patients scheduled for elective surgery requiring general anesthesia with tracheal intubation. Participants will be randomly assigned to receive either HRS-9190 for Injection or Rocuronium.
- Trial name
- NCT07252921
- Testing
- HRS-9190
- Where
- 2 sites in China
- Volunteers
- 70 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Elective Surgery, General Anesthesia
Comparison of Tracheal Intubation in Ramp vs Sniffing Position Using Customized vs Fixed Pillow
The goal of this clinical trial is to find out whether the ramp position or sniffing position is better for endo tracheal intubation which provides better hemodynamic stability and short intubation time and good laryngoscopic…
- Trial name
- NCT07506655
- Testing
- Group A - Fixed Pillow, Group B - Customized Pillow
- Where
- Pakistan
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Obesity Female Patients Require General Anaesthesia With Intubation and Atracurium Curarization
Intubation Conditions With Atracurium After Three Minutes
The purpose of this study is to evaluate intubation conditions with the use of atracurium after a fixed three-minute delay
- Trial name
- CINTROI (NCT04808440)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Apneic Oxygenation
Effect of Continuous Supraglottic Oxygen Insufflation Via Video Laryngoscope Blade on Apneic Oxygenation During Tracheal Intubation Under General Anesthesia
This study is a prospective, randomized controlled clinical trial aimed at investigating the efficacy and safety of a novel oxygenating video laryngoscope blade during apneic oxygenation for intubation under general anesthesia.
- Trial name
- NCT07662304
- Testing
- control group (Group C), The continuous laryngeal oxygen supply group (Group B)
- Volunteers
- 150 people
- Sponsor
- Affiliated Hospital of Jiaxing University
Intubation, Endotracheal
Use of the Stethoscope to Confirm Breathing Tube Placement
This study is intended to validate the use of neck auscultation with an electronic stethoscope during intubation to confirm tracheal tube placement.
- Trial name
- NCT00378651
- Testing
- Neck Auscultation
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Endotracheal Intubation, General Anesthesia
Effect of Different Head Positions During Endotracheal Intubation on Postoperative Sore Throat
The goal of this [ randomized clinical trial] is to [effect of different head positions on the incidence of postoperative sore throat ] in [patients with endotracheal intubation ].
- Trial name
- NCT06059248
- Testing
- the head in the "sniffing position "
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Postoperative Sore Throat, Endotracheal Intubation
Scheduled Endotracheal Tube Cuff Pressure Management and Postoperative Sore Throat
This randomized controlled trial evaluated whether scheduled measurement and adjustment of endotracheal tube cuff pressure using a handheld manometer could reduce postoperative sore throat in adults undergoing elective surgery…
- Trial name
- NCT07842081
- Testing
- Handheld Endotracheal Tube Cuff Manometer, Pilot-Balloon Palpation
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Hitit University
Lung Neoplasms
Effects of Nonintubated Versus Intubated General Anesthesia on Recovery After Thoracoscopic Lung Resection
Lung cancer is the leading cause of cancer death in Taiwan and worldwide. With the advancement of thoracoscopic technique, thoracoscopic surgery has emerged as a reasonable option for the management of early-stage non-small cell…
- Trial name
- NCT02393664
- Testing
- propofol, bupivacaine, sevoflurane, rocuronium
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Perioperative Analgesia, General Anaesthesia
Effect of Transcutaneous Electrical Nerve Stimulation Based on Wrist-ankle Acupuncture Theory on EC50 of Remifentanil Inhibiting Responses to Tracheal Intubation Under General Anesthesia
During endotracheal tube insertion under general anesthesia, sympathetic nerve activity increases, which leads to increased heart rate, increased blood pressure, and increased catecholamine levels in the blood.
- Trial name
- NCT06748898
- Testing
- TENS-WAA, non TENS-WAA
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Changhai Hospital