Clinical trials: General Medicine
COPD
The COPD Optimiser
Rationale: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) report pro- vides clinical treatment guidelines for COPD aimed at relieving and reducing the impact of symptoms, and reducing the risk of adverse health…
- Trial name
- NCT06659666
- Testing
- COPD Optimiser
- Where
- 2 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- General Practitioners Research Institute
HIV, Therapy Failure
A Global Registry On Second gEneration and Long-acting inTegrase inhibiTor fAilures
Integrase strand transfer inhibitors (INSTI) inhibit HIV replication by preventing the integration of viral HIV DNA into the host's genome.
- Trial name
- ROSETTA (NCT06706986)
- Where
- Netherlands
- Volunteers
- 250 people
- Sponsor
- UMC Utrecht
HIV Infections
Missed Opportunities for HIV Screening in General Practice
The number of new HIV diagnoses in France in 2022 is estimated to be between 4,200 and 5,700. Of these diagnoses, 43% of infections were detected at a late stage.
- Trial name
- DepVIH (NCT07303114)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Colorectal Cancer
A Trial of the Implementation of iFOBT in General Practice
Background Colorectal cancer (CRC) is common, and a leading cause of cancer death. The evaluation of patients suspected to have CRC is difficult due to poorly predictive alarm symptoms and many patients present with…
- Trial name
- NCT02308384
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 825 people
- Sponsor
- University of Aarhus
Chemotherapy-induced Nausea and Vomiting
Re-examination Study of EMEND (Aprepitant) (MK-0869-184)
This survey is conducted for preparing application materials for re-examination under the Pharmaceutical Affairs Laws and its Enforcement Regulation.
- Trial name
- NCT01074255
- Testing
- EMEND
- Volunteers
- 3,546 people
- Sponsor
- Merck Sharp & Dohme LLC
Chronic Disease
Prioritising and Optimising Multi-medication in Multimorbidity
Objective: To investigate whether the complex intervention will improve the appropriateness of prescriptions in elderly multi-morbid patients with multi-medication in general practices.
- Trial name
- PRIMUM (NCT01171339)
- Testing
- Optimization strategy (complex intervention)
- Where
- Germany
- Volunteers
- 505 people
- Sponsor
- Goethe University
Epilepsies, Myoclonic, Drug Resistant Epilepsy
Extended Access Program With Lorcaserin For The Treatment of Dravet Syndrome and Other Refractory Epilepsies
The primary purpose of this study is to provide continued access of lorcaserin to participants with Dravet syndrome and other refractory epilepsies.
- Trial name
- NCT04457687
- Testing
- Lorcaserin
- Where
- 22 sites in United States, Canada
- Sponsor
- Eisai Inc.
Postoperative Delirium
The Comparison of Incidence and Risk Factors of Postoperative Delirium in Elderly Patients After Lower Extremity Surgery
The aim of this study is to compare the risk factors and the incidence of delirium following orthopedic surgery under the general or regional anesthesia in elderly patients.
- Trial name
- NCT02360982
- Testing
- propofol and esmeron(rokuronyum), marcaine and fentanyl
- Volunteers
- 120 people
- Sponsor
- Cukurova University
Drug Safety
Efficacy and Safety of Fospropofol in Adult Laparoscopic Surgery: A Clinical Trial
This protocol is a clinical study of fospropofol disodium for general anesthesia in adults undergoing laparoscope-assisted abdominal surgery.
- Trial name
- NCT06573489
- Testing
- Fospropofol, Propofol
- Where
- China
- Volunteers
- 373 people
- Sponsor
- Hui Xu
Asperger's Disorder, Asperger Disorder
QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Parkinson's Disease
A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation
Primary Objectives: Part 1: To determine the safety and tolerability of 4, 8, and 15 milligrams of GZ/SAR402671 (venglustat) administered orally for 4 weeks, as compared to placebo in participants with early-stage Parkinson's…
- Trial name
- MOVES-PD (NCT02906020)
- Testing
- venglustat GZ/SAR402671
- Where
- 52 sites in United States, Austria and 14 more
- Volunteers
- 273 people
- Sponsor
- Genzyme, a Sanofi Company
GERD
PPI Test in GP Patients
The purpose of this study is to determine the diagnostic value of two week treatment with Nexium as a confirmatory test for patients with suspected reflux disease.
- Trial name
- NCT00318084
- Testing
- Esomeprazole, Ambulatory 24-hour esophageal pH-monitoring
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- AstraZeneca
Low Dose Methotrexate in Severe Chronic Asthma
Low-dose Methotrexate for Change in Global Initiative for Asthma Step 5 Medications in Chronic Severe Asthma
Patients with chronic severe asthma (CSA) have a crippling disease and current available treatments are not satisfactory. Thus, management of CSA remains a major unmet need.
- Trial name
- NCT02124226
- Testing
- Methotrexate
- Volunteers
- 102 people
- Sponsor
- University of Catania
Global Medical Assessment of Elderly Frail Patients
Optimization of Drug Treatment in Hospitalized Elderly (OMAGE)
A randomized trial has been designed to determine if this complex intervention can significantly decrease the risk of unplanned readmissions in this very elderly population, compared with usual care.
- Trial name
- OMAGE (NCT00450034)
- Testing
- drug - oriented multifaceted intervention
- Where
- France
- Volunteers
- 665 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris