Clinical trials: General Movements
Dystonia, Focal Dystonia
Brain Changes in Blepharospasm
This study will examine the role of certain areas of the brain in blepharospasm, a type of dystonia (abnormality of movement and muscle tone) that causes unwanted or uncontrollable blinking or closing of the eyelids.
- Conditions
- Dystonia, Focal Dystonia, Cerebellar Disease
- Trial name
- NCT00487383
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Low Back Pain, Chronic Low-back Pain
Effects of Posterior-anterior Vertebral Mobilization Followed by Prone Press-up Exercise in Nonspecific Low Back Pain
Despite advances in intervention, many patients presenting with nonspecific low back pain (NSLBP) fail to have recovery from symptoms and activity limitation.
- Trial name
- NCT05997069
- Testing
- Posterior-anterior vertebral mobilizations followed by Prone press-up exercise, Conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Dr. Aftab Ahmed Mirza Baig
Dystonia
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
Stride Dystonia is a randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of VIM0423 in individuals with isolated dystonia.
- Trial name
- NCT07304089
- Testing
- VIM0423
- Where
- 45 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Vima Therapeutics
Cerebral Palsy
Correlation Between the Analysis of the Rapid Cortical Oscillations, the General Movements of the Preterm's and the Cerebral Palsy
The general movement and the electroencephalogram analysis of the preterm have a high predictive value of the neuro-developmental outcome of the infants.
- Trial name
- NCT00726206
- Testing
- Electroencephalogram, recording the movements
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
General Anesthesia, Intraoperative Awareness
Neuro-Mimic Indicators of Anesthesia Depth During General Anesthesia
This prospective observational study will evaluate neuro-mimic indicators of anesthesia depth, including eyelid reflex, eyeball movements, and pupil responses, in patients undergoing elective surgery under general anesthesia.
- Conditions
- General Anesthesia, Intraoperative Awareness, Eye Movements
- Trial name
- NCT07199049
- Testing
- Neuro-Mimic Observation Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Parkinson Disease, Multiple Sclerosis
TeleNEURO-Rehabilitation Systems for Neurodegenerative Conditions: the FIT4TeleNEURO Pragmatic Trial
The goal of the FIT4TeleNEURO pragmatic trial is to verify, in real-life care contexts, the superiority in terms of the effectiveness of early rehabilitation intervention with Telerehabilitation (TR) protocols (TR single…
- Conditions
- Parkinson Disease, Multiple Sclerosis, Neurologic Diseases, General
- Trial name
- FIT4TeleNEURO (NCT06685744)
- Testing
- Telerehabilitation_TRsA, Educational treatment, Telerehabilitation_TRcA
- Where
- 6 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Constipation
The Effect of Milk Powder With Fiber and Probiotics on Digestive Habits and General Health Well-being of Selected Filipino Mothers.
In-Shape Nutritional Milk Powder is a nutritional milk powder containing fibers, probiotics and other nutrients. This study will focus on the effects of fiber and probiotics on digestive health and health well being in selected…
- Trial name
- NCT01862341
- Testing
- ANMUM In-Shape Nutritional Milk Powder for Active Mothers
- Where
- 4 sites in Philippines
- Volunteers
- 72 people
- Sponsor
- Fonterra Research Centre
Loss of Consciousness, Parkinson Disease
Brain Networks and Consciousness
General anesthesia (GA) is a medically induced state of unresponsiveness and unconsciousness, which millions of people experience every year.
- Conditions
- Loss of Consciousness, Parkinson Disease, Essential Tremor, Anesthesia
- Trial name
- NCT04502550
- Testing
- Propofol
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Texas Southwestern Medical Center
Parkinson's Disease
Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson Disease
Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot from person to person.
- Trial name
- P25-758 PUCCIN (NCT07227896)
- Where
- 10 sites in United States, Israel and 2 more
- Volunteers
- 100 people
- Sponsor
- AbbVie
Neurodevelopmental Disorders, Motor Skills Disorders
Motor Development and Early Predictors of Psychomotor Outcomes in Preterm and Term Infants Assessed by MOS-R and Caregiver Questionnaire at 18 and 36 Months
This study examines how early motor behavior in infants relates to their later psychomotor development. Researchers will observe both preterm and full-term infants during the first months of life, using video-based assessments to…
- Conditions
- Neurodevelopmental Disorders, Motor Skills Disorders, Infant, Premature Development, Infant, Term Development
- Trial name
- NCT07296003
- Testing
- Vojta method
- Where
- 3 sites in Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Advanced Parkinson's Disease
Observational Study Evaluating Long-Term Effectiveness of Duodopa/Duopa in Patients With Advanced Parkinson's Disease
This study is a non-interventional post-marketing observational study (PMOS) of participants with advanced Parkinson's disease (PD) treated with Duodopa/Duopa in a routine clinical setting.
- Trial name
- DUOGLOBE (NCT02611713)
- Where
- 54 sites in United States, Australia and 8 more
- Volunteers
- 213 people
- Sponsor
- AbbVie
Preterm Birth, Early Intervention
Movement Imitation Therapy for Preterm Babies (MIT-PB) - A Pilot Study
Background: Very preterm babies are at high risk for developmental disorders. Prechtl's General Movements (GMs) Assessment is a valuable and reliable tool in infants until three months corrected age for predicting their further…
- Conditions
- Preterm Birth, Early Intervention, General Movements
- Trial name
- NCT07449312
- Testing
- Movement Imitation Therapy for Preterm Babies (MIT-PB), Usual care Physiotherapy
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University of Zurich
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Non-specific Chronic Back Pain
Eye Movement Desensitization and Reprocessing (EMDR) in Non-specific Chronic Back Pain
The study explores the feasibility of Eye-Movement-Desensitization and Reprocessing (EMDR) in non-specific chronic back pain.
- Trial name
- LOGIN - EMDR (NCT01850875)
- Testing
- Eye-Movement-Desensitization-Reprocessing
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Heidelberg
Dravet Syndrome, Severe Myoclonic Epilepsy of Infancy
Treatment of Gait Disorders in Children With Dravet Syndrome
Dravet syndrome is a severe infantile onset epilepsy syndrome with a prevalence of 1/15.000 to 1/30.000. An infant with an apparently normal development presents around 6 months of age with a convulsive status epilepticus.
- Trial name
- T-GaiD (NCT03857451)
- Testing
- Clinical gait analysis
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Universiteit Antwerpen
Parkinson's Disease, Freezing of Gait
Study to Assess the Clinical Benefit and Safety of Droxidopa in Parkinson's Disease
Since droxidopa has been approved in Japan for treating freezing of gait in Parkinson's disease patients, this is to confirm and further investigate the safety and efficacy using a similar dose.
- Conditions
- Parkinson's Disease, Freezing of Gait, Cognitive Ability, General
- Trial name
- NCT02066571
- Testing
- Droxidopa, sugar pill
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Low Back Pain
Movement System Impairment Based Classification Versus General Exercise for Chronic Non-specific Low Back Pain: a Randomised Controlled Trial
The objective of this study is to investigate the efficacy of a treatment based on Movement System Impairment based classification (MSI) model in patients with chronic non-specific low back pain.
- Trial name
- NCT02221609
- Testing
- Treatment based on Movement System Impairment model, General exercise
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- Universidade Cidade de Sao Paulo
Exercise
Caffeine Supplementation on Movement Patterns and Reactive Agility in Rugby Sevens Matches
Caffeine is widely used by rugby players for its performance-enhancing effects. The main questions it aims to answer are: (1) the impact of caffeine supplementation on various performance metrics, including distance covered at…
- Trial name
- NCT06612463
- Testing
- Caffeine 6mg/kg
- Where
- Taiwan
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Shoulder Pain, Musculoskeletal Disease
Scapular Movement Training Versus General Exercises for Individuals With Shoulder Pain
Interventions focused on the scapula have been frequently used to treat shoulder pain. However, most studies do not assess the contribution of scapular movement alteration for the symptoms.
- Conditions
- Shoulder Pain, Musculoskeletal Disease, Joint Disease, Shoulder Injury
- Trial name
- NCT03528499
- Testing
- Scapular Movement Training, General Exercises
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Universidade Federal de Sao Carlos
Neonatal Disease, Parenting
Neonatal Neurobehavioral And Motor Behavior In Ultra Early Physical Therapy Intervention
Investigation of the combination of neonatal neurobehaviourism and motor behavior in the assessment and ultra-early physical therapy intervention of premature neonates and parental support.
- Conditions
- Neonatal Disease, Parenting, Premature Birth
- Trial name
- NCT05565287
- Testing
- ultra early physiotherapy intervention
- Where
- 3 sites in Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly