Clinical trials: Generalized Anxiety Disorder (GAD), active
Generalized Anxiety Disorder (GAD), Depressive and Anxiety Disorders
Miles for Mental Health
Common mental health disorders, like anxiety and depression, are widespread among the American population. The prevalence of mental health disorders among adults continues has consistently increased from previous decades and is…
- Trial name
- NCT07541443
- Testing
- Exercise
- Volunteers
- 20 people
- Sponsor
- Emporia State University
Generalized Anxiety Disorder (GAD), Anxiety Disorders
Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder
This randomized, double-blind, placebo-controlled clinical trial investigates the use of Food and Drug Administration (FDA)-approved cannabidiol (EPIDIOLEX®) as an adjunct to cognitive behavioral therapy (CBT) in adults with…
- Trial name
- CALM (NCT07123467)
- Testing
- Low-Dose Cannabidiol, Moderate-Dose Cannabidiol
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Wayne State University
Generalized Anxiety Disorder (GAD), Worrying
Text Message Safety Behavior Fading for Pathological Worry
The current study aims to explore the efficacy of a text message-based Safety Behavior Fading Intervention compared to a PMR control condition.
- Conditions
- Generalized Anxiety Disorder (GAD), Worrying, Anxiety
- Trial name
- NCT07391020
- Testing
- Safety Behavior Fading for Pathological Worry, Progressive Muscle Relaxation (PMR)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Florida State University
Generalized Anxiety Disorder (GAD)
Device for Treating Generalized Anxiety
The goal of this clinical trial is to learn if treatment with the BTL-699-2 device (non-invasive repetitive transcranial magnetic stimulation) can decrease anxiety symptoms in adults (aged 22 years and older) diagnosed with…
- Trial name
- NCT07819773
- Testing
- EXOMIND (BTL-699-2) Active treatment
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- BTL Industries Ltd.
Generalized Anxiety Disorder (GAD)
Acupuncture for Generalized Anxiety Disorder
Generalized anxiety disorder (GAD) is a common mental disorder characterized by persistent excessive worry, which seriously affects patients' quality of life.
- Trial name
- NCT07798986
- Testing
- 2Hz electro-acupuncture, 100Hz electro-acupuncture, 2Hz/100Hz electro-acupuncture
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Generalized Anxiety Disorder (GAD)
Effectiveness of Solution-Focused Therapy for Generalized Anxiety Disorder in Emerging Adults
This study will evaluate whether Solution-Focused Therapy (SFT) helps reduce symptoms of Generalized Anxiety Disorder (GAD) in emerging adults in Pakistan.
- Trial name
- NCT07798063
- Testing
- Solution-Focused Therapy
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- International Islamic University, Islamabad
Generalized Anxiety Disorder (GAD)
Multimodal Cohort Study of Generalized Anxiety Disorder
Generalized anxiety disorder (GAD) is a common mental health condition characterized by persistent and excessive worry that is difficult to control. It can affect sleep, daily functioning, work, and quality of life.
- Trial name
- MC-GAD (NCT07764211)
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Mental Health Center
Generalized Anxiety Disorder (GAD)
Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety Disorder
This Phase 2a clinical trial is designed to evaluate the safety, tolerability, and preliminary efficacy of a 3 mg dose of psilocybin oral solution for the treatment of Generalized Anxiety Disorder (GAD).
- Trial name
- NCT06969170
- Testing
- Psilocybin (drug)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Claudio N Soares
Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence
Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD
Anxiety disorders in children and adolescents are common and confer significant disability. Cognitive behavioral therapy (CBT) is the recommended treatment for youth with anxiety, yet many families cannot access CBT due to cost…
- Conditions
- Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder (GAD)
- Trial name
- ASTRO (NCT07024758)
- Testing
- Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- Baylor College of Medicine
Generalized Anxiety Disorder (GAD), Chronic Insomnia
Transcranial Alternating Current Stimulation for Generalized Anxiety Disorder and Insomnia: An Open-Label Pilot Study
This is an open-label pilot clinical trial to evaluate the effects of transcranial alternating current stimulation (tACS) in adults diagnosed with generalized anxiety disorder (GAD) and chronic primary insomnia.
- Trial name
- NewWaves (NCT07429578)
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Schizophrenia Disorders, Major Depression
Non-Coding RNAs Gene Expression in Psychiatric Disorders
This study aims to investigate whether specific non-coding RNAs, molecules involved in the regulation of gene expression, are altered in individuals with psychiatric disorders such as schizophrenia, bipolar disorder, major…
- Conditions
- Schizophrenia Disorders, Major Depression, Bipolar Affective Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- PsiRNA26 (NCT07649993)
- Testing
- Reverse Transcription Quantitative Polymerase Chain Reaction
- Where
- 5 sites in Italy
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Carmen Concerto
Generalized Anxiety Disorder (GAD)
Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
Generalized anxiety disorder (GAD) is usually treated with antidepressant therapy (ADT); however, sometimes ADTs alone are not enough to adequately treat GAD.
- Trial name
- NCT06846320
- Testing
- ABBV-932, Antidepressant Therapy (ADT)
- Where
- 52 sites in United States, Puerto Rico
- Volunteers
- 315 people
- Sponsor
- AbbVie
Generalized Anxiety Disorder (GAD)
Transcranial Alternating Current Stimulation to Enhance Mindfulness Therapy in Generalized Anxiety Disorder
This randomized, double-blind, sham-controlled clinical trial will evaluate whether individualized alpha-frequency transcranial alternating current stimulation (tACS) can enhance the effects of mindfulness therapy in adults with…
- Trial name
- NCT07648797
- Testing
- Synchronous Individualized Alpha-Frequency tACS, Desynchronous Individualized Alpha-Frequency tACS, Mindfulness Therapy
- Where
- China
- Volunteers
- 99 people
- Sponsor
- Central South University
Generalized Anxiety Disorder (GAD)
MRI-Guided Accelerated cTBS for Generalized Anxiety Disorder
Generalized Anxiety Disorder (GAD) is a common psychiatric disorder associated with persistent anxiety, functional impairment, and incomplete response to existing treatments.
- Trial name
- NCT07640945
- Testing
- continuous theta burst stimulation(cTBS)
- Volunteers
- 75 people
- Sponsor
- Central South University
Generalized Anxiety Disorder (GAD)
Personalized AI-Driven Models in Cognitive Behavioral Therapy for Anxiety
Untreated anxiety undermines long-term physical and emotional wellbeing, especially among college students, with rates worsening since the onset of the COVID-19 pandemic.
- Trial name
- NCT07430800
- Testing
- Explicit CBT SAR Personalization for 6 weeks, Implicit CBT SAR Personalization for 6 weeks, Control CBT SAR for 6 weeks
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Southern California
Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD)
AI-Supported Therapy for Depression and Anxiety Compared With Standard CBT
This study is a pivotal, randomised, controlled, non-inferiority trial evaluating "Nook," an AI-delivered, neurosymbolic, clinician-supervised digital psychological intervention for depression and anxiety, compared with standard…
- Trial name
- NCT07620340
- Testing
- AI-Digital CBT, Cognitive Behavioural Therapy
- Volunteers
- 400 people
- Sponsor
- PsyScale
Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD)
Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders
The World Health Organization Composite International Diagnostic Interview (CIDI) is a fully structured diagnostic tool designed for lay interviewers to assess the prevalence of mental and substance use disorders.
- Conditions
- Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT07604753
- Testing
- CIDI-5
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Eating Disorders, Anorexia Nervosa
Targeting Social Function in Anxiety and Eating Disorders
Social processing and cognition are often altered in patients with eating disorders. The goal of this clinical trial is to assess two different social therapeutic interventions -- one educational, one interactive -- for their…
- Conditions
- Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Atypical Anorexia Nervosa
- Trial name
- SF (NCT06198023)
- Testing
- Educational, Interactive
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Texas Southwestern Medical Center
Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD)
Transdiagnostic Metacognitive Therapy Compared to Disorder-Specific Cognitive-Behavioral Therapy for Anxiety Disorders
Background Anxiety disorders are the most prevalent psychiatric disorders around the world. Effective treatment consists of pharmacotherapy or psychological treatment based on cognitive-behavioral therapy (CBT) and these…
- Conditions
- Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT06937892
- Testing
- Transdiagnostic metacognitive therapy, Disorder-specific cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 86 people
- Sponsor
- Karolinska Institutet
Major Depressive Episode (MDE), Major Depressive Disorder (MDD)
LHC-CIDI-5 in Hong Kong
The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12…
- Conditions
- Major Depressive Episode (MDE), Major Depressive Disorder (MDD), Persistent Depressive Disorder (PDD), Suicidal Ideation
- Trial name
- NCT06804525
- Testing
- CIDI-5, LHC-CIDI-5
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- The University of Hong Kong