Clinical trials: Genetic Linkage
Healthy
Genetic Component of Handedness
Some functions are generally controlled by the right side of the brain and others by the left. One of the most easily observed examples of this "lateral specialization" of the brain is handedness-that is, a person's preference…
- Trial name
- NCT00005003
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- National Cancer Institute (NCI)
Cardiovascular Diseases
Enhanced Linkage Maps From Family-Based Genetics Studies
To develop genetic maps for the genome-wide screening markers used by multiple investigators and to investigate map differences between sexes and different ethnic groups.
- Trial name
- NCT00049868
- Volunteers
- 1 people
- Sponsor
- Rutgers University
Childhood Absence Epilepsy, Epilepsy
Search for Genes Influencing Childhood Absence Epilepsy (CAE) Study
The purpose of our study is to identify gene(s) involved in the cause of childhood absence epilepsy (CAE).
- Conditions
- Childhood Absence Epilepsy, Epilepsy, Seizures
- Trial name
- NCT00041951
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pesticide Exposure
Incidence and Mortality of Childhood Cancer Among Children of Farmer Pesticide Applications
Previous studies have estabished pesticide exposure as a possible risk factor for childhood cancer. The Agricultural Health Study (AHS), a prospective cohort study of pesticide exposure among 51,000 pesticide applicators in North…
- Trial name
- NCT00339378
- Where
- 3 sites in United States
- Volunteers
- 21,985 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Social Network Strategy, HIV Self Testing
SNS to Increase HIV Testing Uptake and Linkage to Double Cascade Services Among Adolescent MSM and TGW in Thailand
UNAIDS aims to end AIDS by 2030 using "90-90-90" diagnosis-treatment-viral suppression targets. Thailand has achieved elimination of HIV mother-to-child transmission, but continues to see new infections among adolescent men who…
- Conditions
- Social Network Strategy, HIV Self Testing, Men Who Have Sex With Men
- Trial name
- NCT04953858
- Testing
- Social network strategy (SNS)
- Where
- Thailand
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Tuberculosis
Using SMS Reminders, Phone Calls and Money Incentives to Enhance Linkage to Care of Presumptive TB Patients in Uganda
The major challenge in meeting the WHO's End TB Strategy- reducing tuberculosis (TB) deaths by 90% and incidence by 80% is the cascading patient loss-to-follow-up (LTFU) along the continuum of TB care.
- Trial name
- MILEAGE4TB (NCT05964842)
- Testing
- SMS, Phone call, Mobile money incentive
- Where
- 5 sites in Uganda
- Volunteers
- 2,355 people
- Sponsor
- Makerere University
HIV
iLink (Incentives for Linkage to ART) Study: A Mixed-methods Study to Improve Linkage to HIV Care
The iLink Study examines whether a Conditional Economic Incentive (CEI) may be an effective tool for improving linkage to HIV treatment and care following referral for antiretroviral therapy (ART) services from a mobile health…
- Trial name
- iLink (NCT02440386)
- Testing
- Conditional economic incentive
- Where
- South Africa
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Homelessness
Emergency Department Linkage to Care for Patients Experiencing Homelessness
In an effort to improve access to primary care at time of discharge, patients who are homeless will be given either enhanced follow up through a street medicine team or routine follow up in clinic.
- Trial name
- NCT07209072
- Testing
- Street medicine follow up
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Denver Health and Hospital Authority
HIV, Linkage to Care
Impact of Male Provider Phone Calls to Increase Men's Clinic Linkage After HIVST
Evaluate the impact of phone calls from a male counselor in increasing linkage to HIV care and PrEP among male partners of pregnant women attending PMTCT.
- Conditions
- HIV, Linkage to Care, PMTCT, PrEP
- Trial name
- NCT05194085
- Testing
- POC viral load testing, Wellness visit services for male partners
- Where
- Uganda
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV
Testing and Linkage to HIV Care in China
This study will evaluate the effects of a comprehensive approach (One4All) to increase the percentage of patients that receive their HIV testing results and counseling.
- Trial name
- CTN 0056 (NCT02084316)
- Testing
- One4All, Standard of Care
- Where
- 12 sites in China
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
HIV, HIV Testing
Home-based Intervention to Test and Start
This study aims to establish the causal impact of two interventions - micro-incentives and a male-sensitive HIV- specific decision support app - on population-level HIV viral load and HIV-related mortality in men, as well as on…
- Conditions
- HIV, HIV Testing, Linkage to Care
- Trial name
- HITS (NCT03757104)
- Testing
- micro-incentive, EPIC-HIV, micro-incentive and EPIC-HIV
- Where
- South Africa
- Volunteers
- 4,667 people, healthy volunteers welcome
- Sponsor
- Africa Health Research Institute
Hiv
HIV Care Cascade and Linkage to Antiretroviral Therapy Among Hospitalized Adults in Lusaka, Zambia
The population of inpatients is large in Zambia; however, because of poor linkages between hospitals and community HIV care, there are few data to analyze their engagement in HIV care before and after hospitalization.
- Trial name
- COLAH (NCT03158844)
- Testing
- Standard of care
- Where
- Zambia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Alcohol Use, AA Attendance
AA Linkage for Alcohol Abusing Women Leaving Jail
The primary aims of this study are to test the hypotheses that among alcohol abusing and dependent jailed women returning to the community, adding an Alcoholic Anonymous (AA) linkage intervention will result in less alcohol use…
- Conditions
- Alcohol Use, AA Attendance, Sexual Risk Behavior
- Trial name
- NCT01970293
- Testing
- Introduction to AA volunteer
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Frozen Shoulder
Real-time Interactive Digital Healthcare System in Frozen Shoulder; Randomized Controlled Trial
This study aims to examine the effect of hospital-home linkage short-term rehabilitation therapy using real-time interactive digital healthcare system (Uincare Homeplus) in frozen shoulder.
- Trial name
- NCT04316130
- Testing
- Uincare Homeplus, Brochure
- Where
- 2 sites in South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Lung Cancer
Genetic Epidemiology of Lung Cancer
This study will search for genes that greatly increase the risk of developing lung cancer in conjunction with cigarette smoking or other environmental agents, or both.
- Trial name
- NCT00341835
- Where
- United States
- Volunteers
- 6,356 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Hepatitis C Infection
Hepatitis C Infection in World Trade Center Responders
This study provides Hepatitis C virus screening to the members of the World Trade Center Health Program followed at the Icahn School of Medicine at Mount Sinai born during 1945-1965, and linkage to care for those found infected.
- Trial name
- NCT02982993
- Where
- United States
- Volunteers
- 3,906 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Thinness, Leanness
Genome Study in Constitutional Thinness
Constitutional thinness (CT) is a recently defined entity as a differential diagnosis of anorexia nervosa (AN), considered to be the most frequent cause of low body mass index (BMI) in young women.
- Trial name
- GENOSCANN (NCT02525328)
- Testing
- blood or saliva specimen
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
HIV
ENGAGE4HEALTH: A Combination Intervention Strategy for Linkage and Retention in Mozambique
Purpose: To compare the effectiveness of a combination intervention strategy (CIS), consisting of point of care (POC) CD4+ testing immediately following HIV diagnosis and accelerated ART initiation for eligible participants…
- Trial name
- E4H (NCT01930084)
- Testing
- Point of care CD4+ after HIV diagnosis, Accelerated ART initiation, SMS appointment reminders
- Where
- 10 sites in Mozambique
- Volunteers
- 2,004 people
- Sponsor
- Columbia University
Stuttering
Genetic Linkage Studies of Stuttering
Stuttering is an abnormality in speech that affects the rhythm of speech. People who stutter know what they wish to say, but at the time are unable to say it because of involuntary repetition, unnecessary lengthening…
- Trial name
- NCT00001604
- Where
- 3 sites in United States, Japan and 1 more
- Volunteers
- 3,044 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Substance Use Disorders, Treatment Adherence and Compliance
Kentucky Access to Recovery Evaluation
Evaluate the long-term effectiveness of implementing vouchers as a linkage strategy in a population requiring recovery support services (RSS) when no other funding sources are available.
- Trial name
- NCT05889702
- Testing
- KATR Linkage Strategy
- Where
- 2 sites in United States
- Volunteers
- 458 people
- Sponsor
- Terry Bunn