Clinical trials: Genetics Predisposition
Cerebral Palsy
Genetic Predisposition in Cerebral Palsy
Cerebral palsy (CP) is a major neurodevelopmental disorder with an estimated prevalence of approximately one in 500 children. It is characterised by permanent developmental disorders of movement and posture, responsible for…
- Trial name
- PREGENE PC (NCT05317234)
- Testing
- Whole-exome sequencing
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- Hospices Civils de Lyon
Brain Tumors
International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma
The study PNET 5 MB has been designed for children with medulloblastoma of standard risk (according to the risk-group definitions which have been used so far; e.g. in PNET 4).
- Trial name
- NCT02066220
- Testing
- Radiotherapy without Carboplatin, Reduced-intensity maintenance chemotherapy, Radiotherapy with Carboplatin
- Where
- 77 sites in Austria, Belgium and 14 more
- Volunteers
- 360 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Sarcoidosis, Berylliosis
Identifying Shared Genetic Susceptibility Regions in Chronic Beryllium Disease and Sarcoidosis
Granulomatous lung diseases are diseases in which inflamed clusters of white cells, known as granulomas, form in lung tissue. Chronic beryllium disease (CBD) and sarcoidosis are two granulomatous diseases that share similar…
- Trial name
- NCT00560989
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Jewish Health
Acute Leukemia, Adenomatous Polyposis
Familial Investigations of Childhood Cancer Predisposition
NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they enroll.
- Conditions
- Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma, AML
- Trial name
- SJFAMILY (NCT03050268)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- St. Jude Children's Research Hospital
Hereditary Disease, Genetic Predisposition to Disease
Investigating the Feasibility and Implementation of Whole Genome Sequencing in Patients With Suspected Genetic Disorder
The study "Investigating the Feasibility and Implementation of Whole Genome Sequencing in Patients With Suspected Genetic Disorder" is a research study that aims to explore the use of whole genome sequencing as a potential first…
- Trial name
- NCT03829176
- Testing
- Whole Genome Sequencing
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Cystic Fibrosis, Chronic Bronchitis
Standard vs. Biofilm Susceptibility Testing in Cystic Fibrosis (CF)
This was a randomized multi-center clinical trial to compare the microbiological efficacy, clinical efficacy, and safety of using standard versus biofilm susceptibility testing of P.
- Trial name
- NCT00153634
- Testing
- IV amikacin, PO azithromycin, IV ceftazidime
- Where
- 8 sites in United States
- Volunteers
- 75 people
- Sponsor
- Seattle Children's Hospital
Genetic Predisposition to Disease
AHC Ballana Heart Study
This Study is designed to assess CVD incidence, prevalence, progression and related risk factors, including genetic background. It will provide an important base for all cardiovascular research activities in our centre and help…
- Trial name
- AHC-BHS (NCT05661318)
- Testing
- Risk assessment
- Where
- Egypt
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Magdi Yacoub Heart Foundation
Genetic Predisposition, Caffeine
Genetics in the Effect of Caffeine on Fat Oxidation
Genetic polymorphism on the effect of oral caffeine intake on fat oxidation during exercise has been studied in active and healthy population performing an incremental test on a cycle ergometer with 3-min stages at workloads from…
- Conditions
- Genetic Predisposition, Caffeine, Fat Burn
- Trial name
- NCT05975489
- Testing
- Acute caffeine supplementation
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad Francisco de Vitoria