Clinical trials: Genital Infection
Human Papillomavirus Infection
An Information-Motivation-Behavioral Skills (IMB) Intervention to Promote Human Papillomavirus Vaccination Among Women
HPV infections are prominent among college-aged women. Although HPV vaccines decrease women's risk for cervical cancer, vaccination rates remain inadequate.
- Trial name
- NCT02464358
- Testing
- IMB Intervention Group, Attention Control
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Acquired Immune Deficiency Syndrome Virus, HIV Infections
Clinical Trials on the Effect of Immunity 1 (Fuzheng 1) on Immune Reconstitution of HIV Patients
The average period of asymptomatic HIV-infection is 8 years, at this stage, CD4+ T lymphocyte count was reduced gradually at the rate of 50~100cells/ul/year.
- Trial name
- NCT00974285
- Testing
- Fuzheng 1
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
HIV Infections
Impact of Different Integrase Inhibitor Based Regimen on Immune Activation Among HIV naïve Patient (INTATTI)
Low viral replication persistence and immune activation remain important therapeutic challenge in the new HAART era. They are associated with more rapid disease progression, increased risk of mortality and non-AIDS defining…
- Trial name
- INTATTI (NCT03280940)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
HIV Infection, Human Papillomavirus Infection
Incidence of HPV Infection and HPV-Associated Disease in Screening Indian Men Who Have Sex With HIV-Positive Men
This research trial studies the incidence of human papilloma virus (HPV) infection and HPV-associated disease in screening Indian men who have sex with human immunodeficiency virus (HIV)-positive men.
- Conditions
- HIV Infection, Human Papillomavirus Infection, Human Papillomavirus-Related Carcinoma
- Trial name
- NCT04142398
- Testing
- Cytology Specimen Collection Procedure, High Resolution Anoscopy with Biopsy, Laboratory Biomarker Analysis
- Where
- 3 sites in United States, India
- Sponsor
- AIDS Malignancy Consortium
HIV Infections
Phase I/II Study of the Tolerance and Efficacy of Combined Use of Didanosine (2',3'-Dideoxyinosine; ddI) and Lentinan in HIV-Positive Patients
To determine the tolerance and side effects of a combination of lentinan and didanosine (ddI) compared with ddI alone. To determine whether the combination of lentinan and ddI produces a significant immunorestorative effect…
- Trial name
- NCT00002098
- Testing
- Lentinan, Didanosine
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- AJI Pharma USA
Cardiovascular Disease, HIV
Statin Therapy to Improve Atherosclerosis in HIV Patients
In HIV patients, statin therapy will attenuate plaque inflammation, thus, making plaques less vulnerable, will deter plaque progression, and improve endothelial function.
- Conditions
- Cardiovascular Disease, HIV, Atherosclerosis, Inflammation
- Trial name
- NCT00965185
- Testing
- atorvastatin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Breast Cancer, Chronic Myeloproliferative Disorders
Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer
RATIONALE: Biological therapies use different ways to stimulate the immune system and stop cancer cells from growing. Combining chemotherapy and peripheral stem cell transplantation with biological therapy may kill more cancer…
- Conditions
- Breast Cancer, Chronic Myeloproliferative Disorders, Gestational Trophoblastic Tumor, Kidney Cancer
- Trial name
- NCT00003408
- Testing
- aldesleukin, recombinant interferon alfa, sargramostim
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Cancer Treatment Centers of America
Genital Warts, Perianal Warts
Topical NVN1000 for the Treatment of External Genital and Perianal Warts
A Phase 2 Multi-Center, Double-Blind, Randomized, Vehicle-Controlled, Ascending Dose Study Assessing Tolerability, Safety, and Efficacy of Topical NVN1000 in Subjects with External Genital Warts and Perianal Warts
- Trial name
- NCT02462187
- Testing
- NVN1000 8% Gel, NVN1000 16%, Vehicle
- Where
- 15 sites in United States
- Volunteers
- 108 people
- Sponsor
- Novan, Inc.
HPV Infection
Epidemiology of High-risk HPV Infection in Women Participating in a Pilot Screening Program for Cervical Cancer
Cervical cancer is due to a persistent infection with a group of viruses known as high-risk Human Papillomaviruses (hrHPV). Viral DNA can be easily detected in a cervical sample by a procedure called 'HPV testing', which can be…
- Trial name
- Epi-START (NCT02809352)
- Testing
- Human papillomavirus genotyping
- Where
- France
- Volunteers
- 348 people
- Sponsor
- CHU de Reims
HIV Infections
An Imaging Trial of the Distribution of Topical Gel Formulations in the Human Vagina
This study is designed to assess the distribution and spread of four different vehicle formulations in the vagina. In-vivo data will be obtained regarding each vehicle formulation at various time points after insertion of the gel…
- Trial name
- NCT00214747
- Testing
- Vehicle gel formulations
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Biosyn
Urinary Tract Infection Bacterial, Benign Prostatic Hyperplasia
Closed-System Bladder Irrigation to Reduce Urinary Tract Infections After Endoscopic Urologic Surgery (IRIS Trial)
This randomized controlled trial evaluates whether a closed-system bladder irrigation device can reduce the incidence of urinary tract infections in patients undergoing endoscopic urologic surgery.
- Conditions
- Urinary Tract Infection Bacterial, Benign Prostatic Hyperplasia, Bladder Cancer
- Trial name
- IRIS (NCT07510685)
- Testing
- Closed-System Bladder Irrigation Flow Switch Device, Standard Bladder Irrigation
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- University of Pisa
HIV/AIDS
Storytelling Narrative Communication Intervention for Smoking Cessation in Women Living With HIV
HIV has transformed into a chronic illness due to the advent of effective treatments in the absence of a cure. As a result, the prevalence of non-AIDS defining cancers (NADCs), including lung cancer, has increased three-fold…
- Trial name
- WISE (NCT03289676)
- Testing
- Storytelling Narrative Intervention
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Boston
HIV/AIDS
The BRIDGES Project: Bridging Resources to Engage Women in Integrated HIV Care and Support Services
The BRIDGES Project seeks to test a program intended to help women living with HIV who face specific barriers due to culture, gender, violence, trauma, adverse mental health, and substance use to be able to better access HIV…
- Trial name
- BRIDGES (NCT04295876)
- Testing
- The BRIDGES Project Intervention
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego
Metabolic Syndromes, HIV Infection
Pilot Study of Metabolic Syndromes and HIV Infections in Indian Tibetans
Kaohsiung Medical University Chung-Ho Memorial Hospital will provide a long-term free medical service in Indian Tibetans since July 2010.
- Trial name
- NCT01261221
- Where
- Taiwan
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pregnancy, Malaria
Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy
The study aims at comparing the safety, tolerability and efficacy of Mefloquine (MQ) to Sulfadoxine-Pyrimethamine (SP) as Interment Preventive Treatment in pregnancy (IPTp) for the prevention of malaria effects on the mother and…
- Conditions
- Pregnancy, Malaria, HIV Infections
- Trial name
- MiPPAD (NCT00811421)
- Testing
- Sulphadoxine-pyrimethamine, Mefloquine (full dose), Mefloquine (split dose)
- Where
- 5 sites in Benin, Gabon and 3 more
- Volunteers
- 5,820 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
HIV Infections, Depression
The Influence of GINkGo Biloba on the Pharmacokinetics of the UGT Substrate raltEgraviR (GINGER)
The objective of this study is to evaluate the effect of ginkgo biloba (steady state) on the pharmacokinetics of a single dose of the UGT-substrate raltegravir. Furthermore the safety profile of the combination is studied.
- Conditions
- HIV Infections, Depression, Mild Cognitive Impairment
- Trial name
- GINGER (NCT01246804)
- Testing
- raltegravir single dose, ginkgo biloba multiple dose
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
HIV Infections
A Phase I Study to Evaluate the Safety and Toxicity of the Combination of Zidovudine and 2',3'-Dideoxyinosine (Didanosine) in Children With HIV Infection
To assess the safety and tolerance of the combination of zidovudine (AZT) and didanosine (ddI) in children with HIV infection. New approaches to using available agents may provide increased or improved treatment options for AIDS.
- Trial name
- NCT00000652
- Testing
- Zidovudine, Didanosine
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- National Cancer Institute (NCI)
HIV Infections, Memory
Prevalence and Predictors of Neurocognitive Impairment Among HIV-infected Patients
Despite the advent of highly active antiretroviral therapy (HAART), the prevalence of neurocognitive impairment among HIV-infected patients continues to be an important issue.
- Trial name
- NCT00893815
- Where
- 3 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Hiv
Assisted Partner Services and HIVST in Western Kenya
This study includes different designs with Aim 1 being a cluster randomized controlled trial to investigate the use of HIV self-testing (HIVST) as a mode of HIV testing in Western Kenya in addition to the standard of care…
- Trial name
- NCT04774835
- Testing
- HIVST, Standard aPS
- Where
- United States
- Volunteers
- 4,941 people
- Sponsor
- University of Washington
HIV Infection
Correlation of HIV Levels With Clinical and Immunologic Outcome in Children Treated With Didanosine
Recent studies have shown that patients receiving state-of-the-art treatment for HIV infection (highly active antiretroviral therapy, or HAART) show discordant responses to therapy-that is, they improve both clinically and…
- Trial name
- NCT00026676
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- National Cancer Institute (NCI)
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