Clinical trials: Genital Neoplasm
Health Status Unknown, Prostate Carcinoma
Transrectal MRI-Guided Biopsy in Identifying Cancer in Patients With Suspected Prostate Cancer
This pilot clinical trial studies transrectal magnetic resonance imaging (MRI)-guided biopsy to see how well it works in identifying cancer in patients with suspected prostate cancer who are scheduled to undergo standard biopsy.
- Trial name
- NCT02501759
- Testing
- 3 Tesla Magnetic Resonance Imaging, Gadodiamide, Multiparametric Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- OHSU Knight Cancer Institute
Polycystic Ovary Syndrome
Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Polycystic ovary syndrome (PCOS) is a common endocrinopathy affecting 6.5%-6.7% of women in reproductive age, and is commonly associated with obesity, menstrual irregularity, insulin resistance (IR), infertility, and clinical…
- Trial name
- NCT01021579
- Testing
- Metfomin plus Simvastatin
- Where
- Iran
- Volunteers
- 84 people
- Sponsor
- Fasa University of Medical Sciences
Ovarian Cysts
The Effect of Laparoscopic Surgery on Ovarian Reserve According to Cyst Types
The aim of our study is to compare the effect of laparoscopic ovarian cystectomy on ovarian reserve in terms of different cyst types.
- Trial name
- NCT05054946
- Testing
- Laparoscopic cystectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ege University
Ovarian Cancer
The Efficacy of WeChat-based Multidisciplinary Full-course Nutritional Management Program
As the most malignant type of cancer in the female reproductive system, ovarian cancer (OC) has become the second leading cause of death among Chinese women.
- Trial name
- NCT06379191
- Testing
- Nutrition intervention model based on WeChat applets
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Metastatic Castration-resistant Prostate Cancer
A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
The primary objective of this study is to compare overall survival (OS) in participants receiving xaluritamig plus abiraterone against investigator's choice (docetaxel, cabazitaxel, or abiraterone).
- Trial name
- NCT07213674
- Testing
- Xaluritamig, Abiraterone acetate, Docetaxel
- Where
- 159 sites in United States, Australia and 16 more
- Volunteers
- 750 people
- Sponsor
- Amgen
Physical Activity, Cancer Survivor
Move 2 Health: A Couple-Based Physical Activity Intervention for Cancer Survivors
This pilot study will develop and test a couple-based physical activity intervention among cancer survivors and their partners. Aim 1: To determine the feasibility and acceptability of a couple-based physical activity…
- Trial name
- NCT03266718
- Testing
- Physical Activity Intervention
- Volunteers
- 40 people
- Sponsor
- Duke University
Cervical Cancer, Locally Advanced Cervical Cancer
Neoadjuvant Immunochemotherapy in PD-L1-negative LACC
This is a multicenter, prospective, single-arm, phase 2 clinical trial designed to evaluate the therapeutic efficacy of the NACI (neoadjuvant chemotherapy plus Camrelizumab) for PD-L1-negative locally advanced cervical cancer.
- Conditions
- Cervical Cancer, Locally Advanced Cervical Cancer, PD-L1 Negative, Neoadjuvant Chemoimmunotherapy
- Trial name
- NCT06288360
- Testing
- Camrelizumab, Paclitaxel-albumin, Cisplatin
- Where
- 12 sites in China
- Volunteers
- 40 people
- Sponsor
- Tongji Hospital
Ovarian Cancer (Epithelial)
The Efficacy of Involved-field Radiation Therapy for Residual or Locoregionally Recurrent Epithelial Ovarian Cancer After Definitive Treatment; Multi-institutional Clinical Trial
1. Title: The efficacy of involved-field radiation therapy for residual or locoregionally recurrent epithelial ovarian cancer after definitive treatment; Multi-institutional phase 2 clinical trial 2.
- Trial name
- NCT02135523
- Testing
- involved-field radiation therapy
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Yonsei University
Prostate Cancer, Sleep Disturbance
Sleep Hygiene Education, ReadiWatchTM Actigraphy, and Telehealth Cognitive Behavioral Training for Insomnia Effect, on Symptom Relief for Men With Prostate Cancer Receiving Androgen Deprivation Therapy
Many treatments for prostate cancer can cause significant fatigue and/or problems with memory and concentration. Many treatments for prostate cancer also result in disturbed sleep.
- Conditions
- Prostate Cancer, Sleep Disturbance, Fatigue, Cognitive Impairment
- Trial name
- SHERE-Relief 2 (NCT05582759)
- Testing
- teleCBT-I + SH/ReadiWatchTM, SH/ReadiWatchTM
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Kansas Medical Center
Cervical Cancer, Endometrial Cancer
Study of Psychosexual Impact of Cancer-Related Infertility in Women: Third Party Reproductive Assistance
This study aims to learn about the needs and feelings of women who are infertile. Being infertile means not being able to have a child without the help of a third party. There are other options for building a family.
- Conditions
- Cervical Cancer, Endometrial Cancer, Leukemia, Non-Hodgkin's Lymphoma
- Trial name
- NCT00581646
- Testing
- survey instrument
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
Bicalutamide Compared With Observation Followed by Bicalutamide Plus Either Goserelin or Orchiectomy in Treating Patients With Prostate Cancer
RATIONALE: Testosterone can stimulate the growth of cancer cells. Bicalutamide and goserelin may fight prostate cancer by reducing the production of testosterone.
- Trial name
- NCT00014586
- Testing
- bicalutamide, goserelin acetate, orchiectomy
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Breast Cancer, Colorectal Cancer
Printed Education Materials in Patients Who Are Finishing Treatment for Stage I, Stage II, or Stage IIIA Breast Cancer, Colorectal Cancer, Prostate Cancer, or Chest Cancer
RATIONALE: Printed educational materials, such as the Facing Forward Series: Life After Cancer Treatment manual, may help make the transition from cancer patient to cancer survivor easier in patients who are finishing treatment…
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Malignant Mesothelioma
- Trial name
- NCT00372840
- Testing
- educational intervention, psychosocial assessment and care, quality-of-life assessment
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Fox Chase Cancer Center
Cervical Cancer
Exploring the Efficacy, Safety and Cost-effectiveness Analysis of Cadonilimab in the Treatment of Cervical Cancer
Cadonilimab, a PD-1/CTLA-4 bi-specific antibody, is being developed by Akeso, Inc. for the treatment of a range of solid tumors, including cervical cancer, lung cancer, gastric/gastroesophageal junction cancer, liver cancer and…
- Trial name
- NCT06140589
- Testing
- Cadonilimab
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fujian Cancer Hospital
Prostate Cancer
High Dose Rate Prostate Brachytherapy: Dose Escalation to Dominant Intra-prostatic Nodule
This study will investigate the feasibility of using technology of ultrasound guided HDR brachytherapy to focally increase dose to regions within the prostate that are heavily infiltrated with cancer.
- Trial name
- Dosepainting (NCT01605097)
- Testing
- HDR interstitial brachytherapy
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- British Columbia Cancer Agency
Gynecologic Cancer, Carcinoma
Cabozantinib and Dostarlimab in Recurrent Gynecologic Carcinosarcoma
Immunotherapy has gained a significant amount of attention recently, but its efficacy as a single agent in gynecological cancers has been disappointing.
- Conditions
- Gynecologic Cancer, Carcinoma, Uterine Cancer, Endometrial Cancer
- Trial name
- NCT05559879
- Testing
- Cabo + Dostarlimab
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Alabama at Birmingham
Cervical Cancer, Cervical Cancer Screening
My Self-Sampling for HPV Awareness, Results, and Empowerment
The overall objective of this study is to conduct formative research and pilot test the provider-level and patient-level components of the My Self-Sampling for HPV Awareness, Results, and Empowerment (MySHARE+) intervention.
- Conditions
- Cervical Cancer, Cervical Cancer Screening, HPV
- Trial name
- MySHARE+ (NCT07296159)
- Testing
- MySHARE+ mHealth Education Intervention, Healthcare Provider Prompt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Daisy Le
Prostate-specific Membrane Antigen Positive Tumors, Prostate Cancer
A Pilot Study of [Ga-68]PSMA PET/MRI for the Assessment of PSMA-positive Tumors
The purpose of this study is to see if positron emission tomography/ magnetic resonance imaging (PET/MRI) can be used to monitor the effectiveness of cancer treatment using an investigational radioactive drug called [Ga-68]PSMA.
- Conditions
- Prostate-specific Membrane Antigen Positive Tumors, Prostate Cancer, Breast Cancer, Lung Cancer
- Trial name
- NCT02978586
- Testing
- [Ga-68]PSMA PET/MR
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Case Comprehensive Cancer Center
Ovarian Cancer
Doxorubicin + BIBF 1120 in Patients for Ovarian Cancer
The purpose of this trial is to determine whether BIBF 1120 can be safely combined with pegylated liposomal doxorubicin (phase I), and to determine the clinical activity of the combination in patients with platinum-resistant…
- Trial name
- NCT01485874
- Testing
- Doxil (Pegylated Liposomal Doxorubicin), BIBF 1120
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Hoosier Cancer Research Network
Prostatic Neoplasms
Intensity Modulated Radiation Therapy - Prostate Cancer
There are several different treatment schedules being used across the world for treatment of prostate cancer with radiation therapy.
- Trial name
- NCT00188513
- Testing
- conformal intensity modulated radiotherapy (IMRT)
- Where
- Canada
- Volunteers
- 267 people
- Sponsor
- University Health Network, Toronto
Prostate Cancer
Trial of Community Health Worker-led Decision Coaching
Black men are disproportionately affected by prostate cancer, the most common non-cutaneous malignancy among men in the U.S. This randomized trial will evaluate the efficacy of a Community Health Worker-led decision coaching…
- Trial name
- NCT03726320
- Testing
- Education Counseling Session for PSA Screening, General Health Counseling Coaching
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
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