Clinical trials: Genitourinary Disease
Platelet Abnormality, Renal Failure
Hemogram Parameter Changes With Sepsis Filter
Hemodiafiltration is initiated in hemodynamically unstable patients in intensive care units. In some patients, additional devices called cytokine filters or sepsis filters are added to remove inflammatory cytokines.
- Conditions
- Platelet Abnormality, Renal Failure, Immune System Disorder
- Trial name
- NCT06948630
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Samsun University
AIDS Pneumonia, Septic Shock
Clinical Application of Cytokine Adsorption Technique in AIDS Patients With Severe Pneumonia and/or Septic Shock
Observing the Real-World Application Effectiveness of Cytokine Immune Adsorption Technology in AIDS Patients with Severe Pneumonia or septic shock.
- Trial name
- NCT06145828
- Testing
- Cytokine Adsorption
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangzhou 8th People's Hospital
Urinary Tract Stones, Urinary Stones
ESWL for Distal Ureteric Stone: Supine Versus Prone
Extracorporeal shockwave lithotripsy (ESWL) for urinary stone is common and widespread nowadays. Approximately 80% of urinary stones are treated by ESWL.
- Conditions
- Urinary Tract Stones, Urinary Stones, Urinary Calculi
- Trial name
- NCT02298465
- Testing
- Supine ESWL, Prone ESWL, Extracorporeal Shockwave Lithotripsy (ESWL)
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Fetal Growth Retardation
Doppler and AFV for Outcome Prediction ın FGR
The investigator contrived a prospective study of AUCR to compare its association to adverse perinatal outcomes with other established doppler parameters, such as CPR and UCR within a population of suspected FGR fetuses at term.
- Trial name
- NCT05295667
- Testing
- Doppler measurement in combination with amniotic fluid volume
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Bakirkoy Maternity and Children Diseases Hospital
Kidney Diseases, Nephrotic Syndrome
Prospective, Multicenter Study of the Efficacy and Tolerance of Tacrolimus on Refractory Nephrotic Syndrome (RNS)
Exploring the efficacy and safety of Tacrolimus on refractory nephrotic syndrome ; Acquiring the experience of Tacrolimus on the treatment of refractory nephrotic syndrome in Chinese patients.
- Conditions
- Kidney Diseases, Nephrotic Syndrome, Tacrolimus
- Trial name
- NCT00615667
- Testing
- tacrolimus (FK506)
- Volunteers
- 61 people
- Sponsor
- Sun Yat-sen University
Infertility, Female
Assessment of the Feasibility of Frozen Embryo Transfers in a Natural Cycle Among Obese Compared to Non-Obese Patients
This retrospective study included 1,831 single blastocyst frozen embryo transfer (FET) cycles performed between November 1, 2022 and August 31, 2025.
- Trial name
- NATEC (NCT07450300)
- Testing
- Modified natural cycle, Substitued cycle, Hormonal replacement therapy
- Where
- France
- Volunteers
- 1,831 people
- Sponsor
- Clinique Mathilde
Non-muscle-invasive Bladder Cancer
Gemcitabine and Docetaxel Therapy in High-risk BCG-naive Patients With Non-muscle Invasive Bladder Cancer
Bacillus Calmette-Guerin (BCG) is the standard of care for high-risk patients with non-muscle invasive bladder cancer (NMIBC) after transurethral tumor resection.
- Trial name
- NCT05671900
- Testing
- Gemcitabine 1000 mg, Docetaxel 37.5g
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- Clinical Hospital Centre Zagreb
Heart Failure, Congestive
A Safety Study Comparing Natrecor (Nesiritide) Versus Dobutamine Therapy for Worsening Congestive Heart Failure
The purpose of this study is to compare the effects on heart rate and ventricular arrhythmias (irregular heart beats) of two doses of Natrecor® (a recombinant form of the natural human peptide normally secreted by the heart in…
- Trial name
- NCT00270400
- Testing
- nesiritide
- Volunteers
- 255 people
- Sponsor
- Scios, Inc.
Stress Urinary Incontinence
Open Retropubic Versus Laparoscopic Colposuspension (Burch Operation) Techniques for Female Stress or Mixed Urinary Incontinence; A Ten-year Experience in a Tertiary Center
To evaluate postoperative course, efficacy, and complication rates of Open Burch Colposuspension and Laparoscopic Burch Colposuspension techniques in stress or mixed urinary incontinence at a single training and research hospital…
- Trial name
- NCT05452811
- Testing
- Burch colposuspension
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Male Circumcision, HIV Prevention
The Shang Ring: A Novel Male Circumcision Device for HIV Prevention
The purpose of this study is to evaluate the Shang Ring, a novel Chinese device for voluntary medical male circumcision, in order to improve the provision of male circumcision services for HIV prevention in Africa.
- Conditions
- Male Circumcision, HIV Prevention, HIV Infections
- Trial name
- ShangRing (NCT00993811)
- Testing
- Shang Ring circumcision
- Where
- Kenya
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Bacterial Vaginosis
Role of N-Acetylcysteine in Treatment of Bacterial Vaginosis
N-Acetyl cysteine (NAC) is an amino acid with strong antioxidant, mucolytic and antibacterial properties, and is produced within the human body.Its effect in biofilms has been tested in several bacteria.
- Trial name
- NCT01841411
- Testing
- N-Acetyl cysteine, Metronidazole + N-Acetyl cysteine, metronidazole
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Minia University
Prostate Cancer
Efficacy, Safety, and Pharmacokinetics of FP-014, 11.25 mg in Patients With Advanced Prostate Cancer
This is a study in male patients with advanced prostate cancer who are eligible for androgen ablation therapy. The study duration will be up to 26 weeks. Eligibility will be assessed during a screening period of up to 28 days.
- Trial name
- KATANA E3M (NCT06795178)
- Testing
- FP-014
- Sponsor
- Foresee Pharmaceuticals Co., Ltd.
BRCA Mutation, Serous Tubal Intraepithelial Carcinoma
International Registration of Isolated STIC: to Report and Investigate the Risk of Serous Peritoneal Carcinomatosis
To prospectively assess the incidence of peritoneal carcinomatosis for women with isolated STIC (serous tubal intraepithelial carcinoma).
- Conditions
- BRCA Mutation, Serous Tubal Intraepithelial Carcinoma, Ovarian Carcinoma, Peritoneal Carcinoma
- Trial name
- STICRISC (NCT06393543)
- Testing
- No intervention, only registration
- Volunteers
- 600 people
- Sponsor
- Radboud University Medical Center
Endometriosis
Biomarkers in the Endometrial Fluid, Tissue, and Follicular Fluid of Moderate/Severe Endometriosis Patients
This study aims to explore biomarkers in the endometrial fluid and tissue of women with moderate to severe endometriosis, with a specific focus on those involved in pre-receptive endometrium and embryo implantation.
- Trial name
- NCT07182643
- Testing
- Endometrial fluid, Endometrial biopsy, Follicular fluid
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Female Infertility
Caesarean Section and Intracytoplasmic Sperm Injection (ICSI) Outcome
Although Caesarean section (CS) is often a necessary surgical intervention, it may also be associated with an increased risk of short- and long-term sequelae.
- Trial name
- NCT05528835
- Testing
- Frozen embryo transfer
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Alexandria University
Infertility, Psychological Distress
The Effect of IVF Counseling on Psychosocial Well-Being
In this study, İt was aimed to determination of the effect of counseling given in accordance with the Roy Adaptation Model in women in the in vitro fertilization (IVF) process on emotional capacity and well-being.
- Conditions
- Infertility, Psychological Distress, Infertility, Female, Depression, Anxiety
- Trial name
- NCT04703725
- Testing
- Psychosocial Care
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Istanbul University - Cerrahpasa
HIV Infections
Safety and Effectiveness of CD4-IgG2 in HIV-Positive Children
CD4-IgG2 is a special man-made protein that was built to block the entrance of HIV into CD4 cells (cells of the immune system that fight infection).
- Trial name
- NCT00000876
- Testing
- CD4-IgG2
- Where
- 8 sites in United States
- Volunteers
- 12 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Endstage Renal Disease
The Effect of Increasing Dialysate Magnesium on Calcification Propensity in Subjects on Haemodialysis
The purpose of this trial is to examine the effect of increasing dialyse magnesium on serum calcification propensity in subjects with end-stage renal disease treated with haemodialysis.
- Trial name
- NCT02977117
- Testing
- Dialysate magnesium (1.0 mmol/L), Dialysate magnesium (0.5 mmol/L)
- Where
- Denmark
- Volunteers
- 59 people
- Sponsor
- Iain Bressendorff
Clear Cell Renal Cell Carcinoma, Locally Advanced Pancreatic Cancer
Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors
This phase II trial studies how well ceralasertib, am Ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor, works alone or in combination with olaparib or durvalumab in treating participants with renal cell carcinoma…
- Conditions
- Clear Cell Renal Cell Carcinoma, Locally Advanced Pancreatic Cancer, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
- Trial name
- NCT03682289
- Testing
- Ceralasertib, Olaparib, Durvalumab
- Where
- 3 sites in United States
- Volunteers
- 83 people
- Sponsor
- Rahul Aggarwal
Infertility
Comparison of Three Cannulas for Hysterosalpingography
The aim of this study is to compare the three commonly used hysterosalpingography (HSG) injection devices on the basis of patient pain perception, total fluoroscopic and procedural time, and side effects in a prospective…
- Trial name
- NCT00956774
- Testing
- HSG with acorn-tipped cannula, HSG with cervical vacuum cup, HSG with balloon catheter
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Wake Forest University Health Sciences
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