Clinical trials: Genitourinary Symptoms
Chronic Renal Failure
Physical Activity in Dialysis: Clinical and Biological Impact
Physical inactivity is known to increase the risk of developing many diseases as cardiovascular diseases, diabetes, some cancers, and other chronic diseases.
- Trial name
- NCT04525196
- Testing
- Physical activity.
- Where
- 2 sites in France
- Volunteers
- 250 people
- Sponsor
- Elsan
Chronic Kidney Disease (Stages 4 and 5)
Respiratory Biofeedback Added to Strengthening Training in Patients With Chronic Kidney Disease
The goal of this clinical trial is to learn whether diaphragmatic biofeedback added to respiratory muscle training improves clinical and functional outcomes in adults with chronic kidney disease.
- Trial name
- RESPI-REN (NCT07369973)
- Testing
- Diaphragmatic biofeedback combined with respiratory muscle training
- Volunteers
- 24 people
- Sponsor
- Universidad de Granada
Uterine Cervical Neoplasms, Laparotomy
Longitudinal Study of Different Surgical Approaches in Chinese Patients of Uterine Cervical Cancer
This multi-center longitudinal study aims to compare the survival outcomes (including overall survival, progression-free survival and disease-free survival between uterine cervical patients receiving different surgical routes…
- Conditions
- Uterine Cervical Neoplasms, Laparotomy, Laparoscopy, Survival
- Trial name
- NCT03738969
- Testing
- Laparotomic radical hysterectomy, Laparoscopic radical hysterectomy
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Lei Li
Cervical Cancer, Genital Wart
Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9
This study will evaluate the immunogenicity and safety of Zerun 9-valent HPV recombinant vaccine in healthy female 16-26 years of age by comparing with GARDASIL®9.
- Conditions
- Cervical Cancer, Genital Wart, CIN, VIN
- Trial name
- NCT05580341
- Testing
- Zerun HPV-9, GARDASIL ®9
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Kidney Failure, Chronic
Arteriovenous Fistula Tissue Bank for Pre- and Post-Fistula Placement Specimens
This project will bank sera, DNA and vascular specimens from patients undergoing arteriovenous fistula creation and revision.
- Trial name
- NCT00836862
- Testing
- Biologic specimens
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Nebraska
Urinary Incontinence, Vulvar Pruritus
Vulvar Contact Dermatitis Resulting From Urine Incontinence
Vulvar contact dermatitis (VCD) is a common problem presenting as vulvar pruritus, burning or irritation. Its estimated prevalence is 20-30% in vulvar clinics, but the prevalence in the general population is unknown.
- Conditions
- Urinary Incontinence, Vulvar Pruritus, Vulvar Contact Dermatitis
- Trial name
- NCT01320046
- Testing
- Questionnaires, gynecological exam , vaginal smear, and measurement of urine leakage
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Meir Medical Center
Urinary Incontinence, Fecal Incontinence
Safety and Performance of UCon for the Treatment of the Symptoms of Overactive Bladder (OAB) / Bowel Dysfunction (BD)
This clinical investigation is a single-arm, prospective, multicentre, early feasibility study, which is used to evaluate the device design of UCon with respect to initial clinical safety and device performance in a small number…
- Conditions
- Urinary Incontinence, Fecal Incontinence, Urge Incontinence, Nocturia
- Trial name
- NCT05368246
- Testing
- UCon
- Where
- 3 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- InnoCon Medical
Postpartum Hemorrhage
Does the Rapid Intravenous Administration of Oxytocin After Delivery of the Baby Decrease the Bleeding During Cesarean Section in Women at Risk of Bleeding During Cesarean Section?
Oxytocin is normally given either rapidly into the vein (bolus) or put into an intravenous bag and administered more slowly, after delivery of the baby by cesarean section. Both of these methods are commonly used.
- Trial name
- NCT00257803
- Testing
- Oxytocin, Saline solution
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Neurogenic Bladder
Effect of Tamsulosin vs Prazosin in Treatment of Female Voiding Dysfunction
The purpose of this study is to determine whether Tamsolusin or Prazosin are effective in the treatment of female voiding dysfunction(BOO)
- Trial name
- NCT00602186
- Testing
- tamsolusin, prazosin
- Volunteers
- 80 people
- Sponsor
- Tabriz University
Chronic Renal Failure, Chronic Kidney Disease
Extension Study to Evaluate Safety and Tolerability of Peginesatide for Long-Term Treatment of Anemia in Participants With CKD (EU)
The purpose of this study was to evaluate the long term safety and tolerability of peginesatide for the maintenance of hemoglobin in participants with chronic kidney disease (CKD) who had received at least 24 weeks of…
- Conditions
- Chronic Renal Failure, Chronic Kidney Disease, Anemia
- Trial name
- NCT00453973
- Testing
- peginesatide
- Where
- 20 sites in Bulgaria, Poland and 2 more
- Volunteers
- 114 people
- Sponsor
- Affymax
Overactive Bladder (OAB)
Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)
A study to evaluate the safety and effectiveness of FemPulse System
- Trial name
- EVANESCE-II (NCT07195656)
- Testing
- Device Group, Medication Group
- Where
- 15 sites in United States
- Volunteers
- 151 people
- Sponsor
- FemPulse Corporation
Relapsed/Refractory Solid Tumors/Hematological Malignancies
To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.
A phase I, open-label, nonrandomized study to determine the PK profile of belinostat in patients with relapsed/refractory solid tumors or hematological malignancies in patients with renal impairment.
- Trial name
- NCT02679131
- Testing
- Belinostat
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Acrotech Biopharma Inc.
Overactive Bladder, Urinary Incontinence
Effectiveness of Microcurrents Therapy in Overactive Bladder.
The purpose of this study is to investigate the effect on the overactive bladder in women using a care protocol plus the application of microcurrent patches during 1 hours per session compared to the effect of the same protocol…
- Trial name
- NCT04120545
- Testing
- Microcurrents
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- University of Las Palmas de Gran Canaria
Renal Cell Carcinoma
Non-Interventional Study Of Indian Patients With Advanced Renal Cell Cancer Receiving Therapy With Sutent
The Sutent® Observational Study is being proposed to assess the real-world usage patterns and effectiveness and tolerability of treatment of Indian patients with advanced renal cell cancer with Sutent®.
- Trial name
- NCT00836745
- Testing
- Non Interventional
- Where
- 7 sites in India
- Volunteers
- 36 people
- Sponsor
- Pfizer
Uterine Adenomyosis, Recurrent Implantation Failure
Aromatase Plus GnRH Analogue Versus GnRH Analog Alone in Adenomyosis
With this study the investigators want to test which is the best medical treatment for symptomatic adenomyosis affecting women undergoing IVF and with previous implantation failure, between Aromatase inhibitor plus GnRH analog…
- Conditions
- Uterine Adenomyosis, Recurrent Implantation Failure, Menstrual Pain
- Trial name
- NCT03421639
- Testing
- GnRH analog (11.25mg Leuprolide acetate), Aromatase inhibitor and GnRH analog, Aromatase and GnRH analog (11.25mg Leuprolide acetate)
- Where
- 3 sites in Albania, Bulgaria and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre for Endocrinology and Reproductive Medicine, Italy
Bladder Cancer
Comprehensive Geriatric Assessment for Perioperative Optimization in Cystectomy
Patients with muscle-invasive bladder cancer are often older and multimorbid, thus in an increased risk of perioperative mortality and morbidity in relation to radical cystectomy (RC).
- Trial name
- COMPETENCE (NCT05679557)
- Testing
- Perioperative geriatric assessment and intervention
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Aarhus University Hospital
Kidney Disease, End-Stage
PATH-03 Paraguay Feasibility Study
The goal of this study is to evaluate the safety and effectiveness of the ePATH system in the creation of an endovascular AVF (endoAVF) in patients who require or will soon require hemodialysis and are eligible for a fistula.
- Trial name
- NCT07034092
- Testing
- ePATH System will be used to create an endoAVF
- Where
- Paraguay
- Volunteers
- 20 people
- Sponsor
- Pathfinder Medical
Critical Illness, Hyperglycemia
Prognostic Value of Stress Hyperglycemia Ratio in Critically Ill Patients
Critically ill patients admitted to intensive care units (ICUs) frequently develop elevated blood sugar levels (hyperglycemia) as a result of acute illness-related stress, even if they do not have diabetes.
- Conditions
- Critical Illness, Hyperglycemia, Acute Kidney Injury, Multiple Organ Failure
- Trial name
- NCT07853911
- Volunteers
- 230 people
- Sponsor
- Assiut University
Urinary Lithiasis
Stone Disease of the Urinary Tract in Children
The incidence of stone disease of the urinary tract in children is increasingly increasing with a remarkable economic impact for its management.
- Trial name
- Ped-Urolithia (NCT06032364)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Strasbourg, France
Renal Failure, Pain
Effect of Foot Bath on the Severity of Pain, Fatigue and Insomnia in Patients With Acute Renal Failure
One of the non-pharmacological methods that is easily applied, tolerated by the patient, and has no significant side effects is the foot bath.
- Trial name
- Foot Bath (NCT06613087)
- Testing
- Foot bath
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Amasya University