Clinical trials: Geriatric, open to volunteers
Diabetes, Older People
Comprehensive Approach to Reduce Elderly Functional Decline in Diabetes: the CARED Study
Importance. Conventionally, treatment goals for diabetic patients primarily target glycemic levels and traditional cardiovascular risk factors (blood pressure, lipids) control to reduce macro- and micro-vascular complications.
- Trial name
- CARED (NCT06842459)
- Testing
- Geriatric Assessment
- Where
- 2 sites in Italy
- Volunteers
- 180 people
- Sponsor
- University of Cagliari
Cancer
Dyadic Life Review Intervention for Older Patients With Advanced Cancer and Alzheimer's Disease and Related Dementias and Their Caregivers
The purpose of this study is to evaluate the efficacy of Dyadic Life Review (DLR) therapy for reducing caregiver distress, measured by caregiver burden to capture the multifaceted experience of distress, among older adults with…
- Trial name
- NCT07796347
- Testing
- Dyadic Life Review
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Rochester
Breast Cancer, Parenting Anxiety
Development and Application of a Parenting Anxiety Intervention Program for Young and Middle-Aged Female Breast Cancer Patients
This feasibility study aims to develop and test an intervention program for young and middle-aged female breast cancer patients who experience parenting concerns.
- Trial name
- NCT07331740
- Testing
- Parenting Concerns Support Program
- Volunteers
- 20 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Late Life Depression
Chronic Anergic Depression IDentification - Magnetic Resonance Imaging Exploration in the Elderly of Traits Related to Onset
Depression in the elderly, or "late life depression" (LLD), is often considered to be homogeneous, legitimizing standardized treatment.
- Trial name
- CAnD'ID-METRO (NCT06663891)
- Testing
- Functional MRI with EEG per MRI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Guided Imagery
The Effect of Guided Imagery on Activity-Specific Balance Confidence, Pain, and Psychological Well-Being
The aim of this clinical trial is to evaluate the effect of guided imagery on activity-specific balance confidence, pain, and psychological well-being in elderly orthopedic patients.
- Trial name
- NCT06855927
- Testing
- Guided Imagery
- Volunteers
- 78 people
- Sponsor
- Inonu University
Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia
A Study of Sonrotoclax (BGB-11417) in Children With Relapsed or Refractory Acute Myeloid Leukemia and B-cell Acute Lymphoblastic Leukemia
The goal of this clinical trial is to learn if sonrotoclax (BGB-11417) is safe and may help treat children and adolescents with acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) that has come back after treatment…
- Conditions
- Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, B-cell Acute Lymphoblastic Leukemia, Pediatric Cancer
- Trial name
- NCT07770698
- Testing
- sonrotoclax, Azacitidine, Inotuzumab ozogamicin
- Volunteers
- 30 people
- Sponsor
- BeOne Medicines
Cognitive Decline, Aging
Effects of Comprehensive Community Support Programs on Cognitive Function and Quality of Life in Older Adults
This prospective observational study aims to investigate the effects of a multidomain community-based support program on cognitive function and quality of life in older adults attending the Vefahane Life Center in Istanbul…
- Conditions
- Cognitive Decline, Aging, Quality of Life
- Trial name
- NCT07610109
- Testing
- Multidomain Community Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Medipol University Hospital
Dementia, Agitation
Virtual Reality to Advance Dementia Care and Quality of Life
The goal of this feasibility clinical trial is to learn whether supervised virtual reality (VR) sessions can be safely and practically provided to adults aged 55 years and older with moderate-to-severe dementia who experience…
- Conditions
- Dementia, Agitation, Behavioural and Psychological Symptoms of Dementia, Major Neurocognitive Disorder
- Trial name
- VR-Care (NCT07893678)
- Testing
- Supervised Virtual Reality Sessions
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Localized Cutaneous Leishmaniasis
A Clinical Trial to Investigate Efficacy, Safety and Pharmacokinetics (PK) of Two LXE408 Oral Regimens and Oral Miltefosine as Active Control in Participants Aged ≥ 18 Years Old With Localized Cutaneous Leishmaniasis in the Region of the Americas (AMR).
The purpose of this clinical trial is to measure efficacy, safety and pharmacokinetics (PK) of two LXE408 oral regimens and oral miltefosine tablets as active control in localized cutaneous leishmaniasis in the region of the…
- Trial name
- NCT06997159
- Testing
- LXE408, Miltefosine 50 MG Oral Capsule [Impavido]
- Where
- 5 sites in Brazil, Panama
- Volunteers
- 250 people
- Sponsor
- Drugs for Neglected Diseases
Postoperative Delirium, Gastrointestinal Tumors
Opioid-free Anesthesia and Postoperative Delirium
Postoperative delirium (POD) is a common acute and transient form of brain dysfunction in elderly patients following surgery that can lead to serious adverse clinical outcomes and even death.
- Trial name
- NCT07603596
- Testing
- OFA group, OBA group
- Volunteers
- 174 people
- Sponsor
- Qianfoshan Hospital
RSV Infection
RSV Vaccination in Immunocompromised Patients.
Respiratory syncytial Virus (RSV) causes respiratory infections worldwide and typically presents with a seasonal pattern peaking in autumn/winter in temperate climate zones.
- Trial name
- NCT06597916
- Testing
- Arexvy powder and suspension for injection
- Where
- Austria
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy
Effectiveness of an mHealth Application to Promote Home-Based Exercise in Adults Aged 65 and Older
The goal of this clinical trial is to learn if drug ABC works to evaluate the effectiveness of an mHealth application to promote home-based exercise in adults aged 65 and older.
- Trial name
- HOME-FIT (NCT06983574)
- Testing
- MIA
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- PXL University College
Frailty, Older People
A Service-Learning Program for Comprehensive Geriatric Assessment and Health Promotion in Older Adults
The GEROS Project aims to develop and implement a Service-Learning (S-L) program that integrates Comprehensive Geriatric Assessment (CGA) and health promotion, for students at the Faculty of Health Sciences and Welfare at the…
- Conditions
- Frailty, Older People, Comprehensive Geriatric Assessment, Health Promotion
- Trial name
- GEROS (NCT06890325)
- Testing
- Comprehensive Geriatric Assessment (CGA), Health education
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Cancer
A New Psychotherapy Intervention for Older Cancer Patients
This study is being done to see if a new psychotherapy intervention called Cancer and Aging: Reflections for Elders (CARE) can effectively treat depression and distress in older cancer patients.
- Trial name
- NCT04452825
- Testing
- Cancer and Aging: Reflections for Elders (CARE) Intervention, Social Work and Supportive Counseling (SWSC) Intervention
- Where
- United States
- Volunteers
- 459 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Suicidal Ideation, Suicide Attempt
Attempted Suicide Short Intervention Program for Older Adults (ASSIP-OA): An Evaluation of a Psychosocial Intervention for Suicidal Adults Aged 65+
Older adults are sorely underrepresented in suicide prevention research, despite the fact that suicide rates are higher in this age group than in any other age group in Sweden and in many countries worldwide.
- Conditions
- Suicidal Ideation, Suicide Attempt, Suicide
- Trial name
- NCT06831942
- Testing
- ASSIP-OA, Treatment as Usual (TAU)
- Where
- 2 sites in Sweden
- Volunteers
- 132 people
- Sponsor
- Vastra Gotaland Region
Autism Spectrum Disorder (ASD)
An Empowering Parent Training Intervention to Increase Physical Activity in Preschool Aged Children With Autism
The goal of this clinical trial is to learn if WE PLAY for Parents can improve caregivers' knowledge, attitudes, confidence, and skills promoting physical activity with their young child with autism.
- Trial name
- NCT07421830
- Testing
- Wellness Enhancing Physical Activity for Young Children: Parent Version (WE PLAY for Parents)
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Cognitive Dysfunction, Cognitive Disorder, Dietary Supplements
INSIDE: Intervention in Nutritional Supplementation to Improve Cognitive Decline in Elderly.
This study investigates the effect of nutritional supplementation on cognitive performance in older adults over a 90-day period using a double-blind randomized controlled design.
- Trial name
- INSIDE (NCT07000500)
- Testing
- Nutritional Supplement
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Maria Paço
ADHD
Forward Treatment of Attention Deficit and Hyperactivity Using Solriamfetol (FOCUS-3)
This study is a Phase 3, multi-center, randomized, 6-week, double-blind, placebo-controlled, parallel-group trial to assess the efficacy and safety of solriamfetol in adolescents aged 12 to <18 years with ADHD.
- Trial name
- NCT07717892
- Testing
- Solriamfetol Dose A, Solriamfetol Dose B
- Where
- 28 sites in United States
- Volunteers
- 468 people
- Sponsor
- Axsome Therapeutics, Inc.
Geriatric Patients
Attitudes and Beliefs Related to Benzodiazepine Deprescribing
The use of benzodiazepines in older adults is associated with an increased risk of adverse effects due to age-related physiological changes.
- Trial name
- BENZ-AC (NCT07474532)
- Testing
- Patient rPATD Benzo questionnaire, Geriatrician rPATD Benzo questionnaire
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Hospices Civils de Lyon
Community-Acquired Pneumonia, Fraility
Frailty and Outcomes in Older Emergency Department Patients With Pneumonia
Pneumonia is one of the leading causes of infection-related mortality in the older population. Traditional severity scores used in emergency departments, such as the Pneumonia Severity Index (PSI) and CURB-65, primarily focus on…
- Conditions
- Community-Acquired Pneumonia, Fraility, Hospitalizations
- Trial name
- NCT07442656
- Testing
- Clinical frailty scale, Clinical Frailty Scale (CFS)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ege University