Clinical trials: Geriatric Cancer Patients
Patients Aged 50-75 and Requiring Colonoscopy
The French Gut-colo
Colorectal cancer (CRC) is the second most common type of cancer worldwide. The European Union recommends national CRC screening for people aged between 50 and 74.
- Trial name
- NCT06174233
- Where
- France
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Neoplasms, Cardiac Arrhythmia
Beat to Beat A Study in Paediatric, Adolescent and Young Adult Patients Who Are Undergoing or Have Undergone Cancer Therapy to Evaluate the Agreement Between QTc Measured Using 12 Lead Electrocardiogram (ECG) and a Wearable Device ECG
A prospective study in paediatric, adolescent and young adult patients aged 7 to 18 years to evaluate the agreement between QTc measured using 12 lead electrocardiogram (ECG) and the wearable device ECG.
- Trial name
- NCT05615376
- Testing
- ECG application, 12 lead ECG
- Where
- Australia
- Volunteers
- 45 people
- Sponsor
- Murdoch Childrens Research Institute
Neoplasms, Frailty
Ready for Safe Cancer Treatment (RESET): A Comprehensive Perioperative Program for Surgical Oncology
The goal of this randomized controlled clinical trial is to evaluate whether the Ready for Safe Cancer Treatment (RESET) program improves perioperative care and supports safe hospital discharge in two surgical populations: adult…
- Conditions
- Neoplasms, Frailty, Surgical Procedures, Operative
- Trial name
- RESET (NCT07727876)
- Testing
- RESET multimodal perioperative care pathway, Standard perioperative care
- Where
- 2 sites in Poland
- Volunteers
- 12,800 people
- Sponsor
- Regional Specialist Hospital in Wroclaw
Post-induction Hypotension (PIH), Geriatric Patient
Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients
This observational clinical study aims to investigate the incidence and risk factors of post-induction hypotension (PIH) in geriatric cancer patients undergoing surgery under general anesthesia.
- Conditions
- Post-induction Hypotension (PIH), Geriatric Patient, Oncologic Disease, Hemodynamic Effects of General Anesthesia
- Trial name
- NCT07294040
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Dolunay ARIK
Non-small Cell Lung Cancer Metastatic, Non-small Cell Lung Cancer Stage IIIB
MILES-4: Study Comparing Gemcitabine and Pemetrexed, With or Without Cisplatin, in Patients With Nonsquamous Lung Cancer
The purposes of this study are to test whether the addition of cisplatin to single agent chemotherapy (either gemcitabine or pemetrexed) prolongs survival in elderly patients with non squamous non small cell lung cancer (NSCLC)…
- Trial name
- MILES-4 (NCT01656551)
- Testing
- Gemcitabine, Pemetrexed, Cisplatin
- Where
- 48 sites in Italy
- Volunteers
- 232 people
- Sponsor
- National Cancer Institute, Naples
Colorectal Cancer Control and Prevention
Self-Reported Colorectal Cancer Screening Uptake
This randomized controlled trial evaluated the effect of a Health Belief Model-based multicomponent education program on colorectal cancer screening completion, knowledge, health beliefs, and screening attitudes among adults aged…
- Trial name
- CRC-HBM (NCT07778875)
- Testing
- Health Belief Model-Based Colorectal Cancer Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Elderly, Cancer
Elderly CAncer Patient: Qualitative and Quantitative Factors of Inclusion Failure in Clinical Trials
The transposition of the results of biomedical research to medical management of patients in real-life setting depends highly from patient's selection.
- Conditions
- Elderly, Cancer, Ethnographic Interview, Social Representation of Being Aged
- Trial name
- Quali-SAGE (NCT03230305)
- Testing
- Ethnographic interview
- Where
- France
- Volunteers
- 313 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastric Cancer, Adenocarcinoma of the Esophagogastric Junction
Oxaliplatin and 5-Fluorouracil With or Without Docetaxel in Elderly Patients (>65 y) With Stomach and Esophagus Cancer
In this trial, FLOT will be evaluated as therapy option for elderly patients (>65 years) with advanced gastric cancer in comparison to the well established FLO scheme.
- Trial name
- NCT00737373
- Testing
- Docetaxel, 5-Fluorouracil, Oxaliplatin
- Where
- Germany
- Volunteers
- 143 people
- Sponsor
- Krankenhaus Nordwest
Breast Cancer, Colon Cancer
Feasibility of an Evidence-based Walking Program in Cancer Pts 60+ During Chemotherapy
The study will look at conducting a medium-intense walking program called Walk With Ease with cancer patients age 60 and above who are starting chemotherapy treatment.
- Conditions
- Breast Cancer, Colon Cancer, Lung Cancer
- Trial name
- WWE (NCT01789983)
- Testing
- Walk With Ease Program, Collect Blood, GA and Other Survey Tools
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Leukemia, Myeloid, Acute, De Novo
Clinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine Plus Venetoclax and Quizartinib in Newly Diagnosed AML Patients Aged Equal or More Than 60 Years Old
A phase I-II trial based on the combination of three drugs regimen LDAC or Azacitidine + Venetoclax + Quizartinib that in this population could be well tolerated by a sequential type administration.
- Conditions
- Leukemia, Myeloid, Acute, De Novo, Age More 60yr
- Trial name
- NCT04687761
- Testing
- Azacitidine, Venetoclax, Quizartinib
- Where
- 15 sites in Spain
- Volunteers
- 113 people
- Sponsor
- PETHEMA Foundation
HNSCC, Oral Cavity Cancer
Special Care Patterns for Elderly HNSCC Patients Undergoing Radiotherapy
The number of elderly head-and-neck squamous cell carcinoma (HNSCC) patients is increasing; however, the evidence regarding the ideal treatment for this often vulnerable and frail patient cohort is limited.
- Conditions
- HNSCC, Oral Cavity Cancer, Oropharynx Cancer, Hypopharynx Cancer
- Trial name
- SENIOR (NCT05337631)
- Where
- 18 sites in United States, Cyprus and 3 more
- Volunteers
- 1,500 people
- Sponsor
- University Hospital Freiburg
Multiple Myeloma
Randomized Phase II Study in Elderly Patients With Newly Diagnosed Multiple Myeloma
To compare the efficacy and safety of bortezomib, lenalidomide and dexamethasone in elderly frail patients with newly diagnosed multiple myeloma.
- Trial name
- KMM1910 (NCT04277845)
- Testing
- Bortezomib, Lenalidomide, Dexamethasone
- Where
- South Korea
- Volunteers
- 49 people
- Sponsor
- Samsung Medical Center
Colorectal Cancer
Inclusion of Elderly Patients With Colorectal Cancer in Clinical Trials
Background: Inadequate representation of elderly cancer patients in randomized clinical trials (RCTs) leading to a lack of external validity thereby an uncertainty regarding benefit-risk balance of cancer treatment in elderly…
- Trial name
- SAGE (NCT01754636)
- Testing
- No intervention
- Where
- France
- Volunteers
- 707 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lung Cancer
Celecoxib and Docetaxel in Treating Patients With Non-Small Cell Lung Cancer
RATIONALE: Celecoxib may slow the growth of cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00030407
- Testing
- Celecoxib, Docetaxel
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Aged Patients Treated for Cancer in Outclinics
Falls Among the Older Patients Treated for Cancer in Normandy's Outclinics: Screening and Prevention
The French Plan National AntiChute (published on February 21, 2022) and international recommendations on falls prevention (Age Ageing,September 2022) recommend identifying the risk of falling in people aged 65 and over, at least…
- Trial name
- CHUPACHOUP (NCT06504628)
- Testing
- screening risk for falling and identifiy the risk level low-intermediate-high, 3 mnth-follow-up
- Where
- 10 sites in France
- Volunteers
- 328 people
- Sponsor
- University Hospital, Caen
Breast Cancer, Prostate Cancer
A Pilot Study of Geriatric Specific Interventions for Quality of Life in Elderly Patients With Cancer
The purpose of this study is to examine whether psychoeducation counseling for older cancer patients undergoing treatment is feasible and worthwhile.
- Conditions
- Breast Cancer, Prostate Cancer, Lung Cancer, Lymphoma Cancer
- Trial name
- NCT00984321
- Testing
- group intervention and questionnaires, individual phone intervention and questionnaires, expressive writing (arm will not be include in the randomization)
- Where
- 2 sites in United States
- Volunteers
- 107 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Non-Small Cell Lung Cancer
Study of Stereotactic Ablative Radiotherapy (SABR) in Elderly Stage I NSCLC
This study aims to prospectively investigate the efficacy, toxicity and quality of life (QOF) of stereotactic ablative radiotherapy (SABR) using a moderate fractionation of 72 Gy/6 Gy/12 F (BED10 = 115 Gy) in a single arm of…
- Trial name
- NCT02584699
- Testing
- Stereotactic Ablative Radiotherapy (SABR)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Luhua Wang
Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia
A Study of Sonrotoclax (BGB-11417) in Children With Relapsed or Refractory Acute Myeloid Leukemia and B-cell Acute Lymphoblastic Leukemia
The goal of this clinical trial is to learn if sonrotoclax (BGB-11417) is safe and may help treat children and adolescents with acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) that has come back after treatment…
- Conditions
- Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, B-cell Acute Lymphoblastic Leukemia, Pediatric Cancer
- Trial name
- NCT07770698
- Testing
- sonrotoclax, Azacitidine, Inotuzumab ozogamicin
- Volunteers
- 30 people
- Sponsor
- BeOne Medicines
Colorectal Neoplasms
Are Sporadic Colorectal Cancers in Young Distinct From Elderly?
In this study, the investigators compared and evaluated the clinicopathological and oncological characteristics of sporadic colorectal cancer (CRC) in young adults without genetic mutations associated with hereditary CRC syndrome…
- Trial name
- NCT05601609
- Where
- South Korea
- Volunteers
- 1,599 people
- Sponsor
- Seoul National University Bundang Hospital
Unspecified Adult Solid Tumor, Protocol Specific
Screening Tools to Predict Treatment Outcome in Older Cancer Patients Who Are Undergoing Treatment
RATIONALE: Questionnaires that measure how well older patients think, learn, remember, and make judgments and carry out daily activities may improve the ability to plan treatment for patients with cancer.
- Trial name
- NCT01005693
- Testing
- questionnaire administration, cognitive assessment, examination
- Where
- 4 sites in Belgium
- Volunteers
- 300 people
- Sponsor
- Ziekenhuis Netwerk Antwerpen (ZNA)
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