Clinical trials: Geriatric Disorders
Urinary Retention, Postoperative Complications
Comparison of Laparoscopic and Open Inguinal Hernia Repair in Elderly Patients
Inguinal hernia is one of the most frequently performed surgeries in general surgery. This surgery can be performed with both open and laparoscopic techniques.
- Conditions
- Urinary Retention, Postoperative Complications, Pain, Relapse
- Trial name
- NCT06417346
- Testing
- Laparoscopic TEP Repair, Open Technique (Lichtenstein)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Mehmet Eşref Ulutaş
Traumatic Brain Injury
Outcome in Traumatic Brain Injury Elderly Patients
In patients suffering from traumatic brain injury (TBI), the study's purpose was to determinate factors associated with mortality and poor functional outcome at 3 months in patients aged ≥ 65 hospitalized in ICU and to compare…
- Trial name
- NCT04651803
- Volunteers
- 1,633 people
- Sponsor
- Association pour la Recherche en Aanesthésie Réanimation Digestive
Geriatric Patient Care Improvement, EEG Data Analysis
Anesthetic Agent Titration With EEG Wave Analysis
Several studied shown that when general anesthesia is applied under BIS guidance, anesthetic doses are reduced. Additionally it has been found that the risk of postoperative delirium (POD) is reduced and postoperative recovery is…
- Trial name
- NCT07266727
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University
Chronic Disease
Adapted Physical Activity Centre (in The) CITY for Elders Aged 70 and Over with At Least One Long Term Illness
Elders aged 70 and over, living in Toulouse, with a chronic disease identified by the French social insurance as an Affection Longue Durée will be eligible to a 4 months physical activity program in a primary health center.
- Trial name
- CAPACITY70 (NCT04644861)
- Testing
- Program of adapted physical activity
- Where
- France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Toulouse
Epidemic Meningitis, Meningococcal Vaccines
Phase Ⅲ Trial of Group ACYW135 Meningococcal Conjugate Vaccine in Children Aged 6-11 Months
The goal of this clinical trial is to evaluate the immunogenicity, safety, and persistence of the immune response of a group ACYW135 meningococcal conjugate vaccine in healthy children aged 6 to 11 months.
- Trial name
- NCT07505823
- Testing
- experimental vaccine, Active Comparator vaccine
- Where
- 2 sites in China
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Esophageal Cancer
Gefitinib Combined With Radiotherapy in Elderly Patients With Esophageal Cancer
Elderly patients with esophageal cancer will receive thoracic radiation therapy 54-60Gy over 30 fractions, and concurrent with Gefitinib.
- Trial name
- NCT01291823
- Testing
- gefitinib, Thoracic radiotherapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Zhejiang Cancer Hospital
Rare Diseases
Evaluation of Socio-professional Inclusion for Young Adults Aged 15-25 Living With a Rare Genetic Disability
Rare diseases are often synonymous with difficulties for sufferers, whether physical, mental or social. Patients suffering from rare diseases face specific problems, such as the long wait for a diagnosis, the geographical…
- Trial name
- ImagineLaSuite (NCT07527624)
- Testing
- survey
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Imagine Institute
Multiple Myeloma
Velcade, Melphalan, Prednisone And Thalidomide Versus Velcade, Melphalan, Prednisone in Multiple Myeloma Patients
The proposed study will evaluate whether the combination of VELCADE, Thalidomide , Melphalan and Prednisone (V-MPT), as induction treatment for newly diagnosed elderly MM patients, improves outcomes compared to the combination…
- Trial name
- NCT01063179
- Testing
- Bortezomib, Melphalan, Prednisone, Thalidomide, Bortezomib, Melphalan, Prednisone
- Where
- Italy
- Volunteers
- 511 people
- Sponsor
- Fondazione EMN Italy Onlus
Shoulder Pain
Effectiveness of Pain Education Elderly Subacromial Pain
Objective: To verify the effectiveness of education in pain added to other treatment modalities (manual therapy and exercises) in the outcomes of pain, functionality, depression, anxiety, stress, kinesiophobia, self-efficacy and…
- Trial name
- Subacromial (NCT04941586)
- Testing
- Education in pain, Manual Therapy and Exercises, Manual Therapy and Exercises
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Rodrigo Gustavo da Silva Carvalho
eHealth
Dr Solitaire: Assessing Cognitive Performance Through Meaningful Play
To assess cognitive performance by means of the game of Solitaire. In this study, the investigators want to define relevant game metrics, when playing Solitaire, that may be indicative of cognitive performance.
- Trial name
- NCT02971124
- Where
- 2 sites in Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Smallpox, Monkeypox
Safety and Tolerability Study of the VAC∆6 Vaccine in Volunteers Aged 18-40 Years
The aim of the clinical study is to study the safety and tolerability of the live cell-based vaccine against smallpox and other orthopoxvirus infections (VAC∆6 vaccine) based on vaccinia virus, in intracutaneous administration.
- Conditions
- Smallpox, Monkeypox, Cowpox, Vaccinia Virus Infection
- Trial name
- NCT05762523
- Testing
- VAC∆6 vaccine - оnce at a dose of 10⁶ PFU, VAC∆6 vaccine - once at a dose of 10⁷ PFU, VAC∆6 vaccine - twice at a dose of 10⁶ PFU
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector"
Caries, Dental
Effect of Lactobacillus Rhamnosus GG and Bifidobacterium Longum in Children Aged 3 to 5 Years of Villavicencio and Pasto
The objective of this pilot study is to determine if the presence of bacteria with probiotic characteristics (Lactobacillus rhamnosus GG and Bifidobacterium longum) in a commercial milk, control some measures that indicate…
- Trial name
- NCT03078179
- Testing
- Commercial Dairy Cow Milk, Commercial Cow Milk with Probiotic
- Where
- 3 sites in Colombia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cooperative University of Colombia
Dyslipidemia
Effect of Nigella Sativa on Lipid Profiles in Elderly
The purpose of this study is to determine whether Nigella sativa seed extracts are effective in the treatment of dyslipidemia in elderly.
- Trial name
- NCT01531062
- Testing
- Nigella sative, black sticky rice
- Where
- Indonesia
- Volunteers
- 96 people
- Sponsor
- Universitas Indonesia
Alaska Native Youth Aged 14 - 24, Suicide, Attempted
Suicide Intervention for Alaska Native Youth
Two interventions will be delivered virtually to American Indian/Alaska Native youth who have been hospitalized with suicidal attempt, suicidal ideation, or associated risk behaviors, including alcohol-related injury.
- Conditions
- Alaska Native Youth Aged 14 - 24, Suicide, Attempted, Suicidal Ideation, Alcohol Intoxication
- Trial name
- BeWeL (NCT05360888)
- Testing
- Tools for Life, Tools for Life + MISN
- Where
- 2 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- RAND
Coagulopathy, Trauma
Effect of Hypocalcemia on the Outcome of Elderly Major Trauma Patients With Trauma-induced Coagulopathy
Hypocalcaemia is an independent risk factor of TIC in elderly trauma patients. TIC combined with hypocalcemia had worse coagulation function and more serious acidosis.
- Trial name
- NCT05530161
- Testing
- hypocalcemia
- Where
- China
- Volunteers
- 371 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Geriatric, Frailty, Emergency Department
FRailty Among Elderly Emergency Department Patients With Outcome Measures
Our study aims to compare 4 clinical frailty scores, namely Clinical Frailty Scale (CFS), Edmonton Frail Scale (EFS), FRAIL 5-item scale (FRAIL) and SARC-F Sarcopenia Score (SARC-F), which can potentially be adopted for daily…
- Trial name
- FREEDOM (NCT03814161)
- Where
- Singapore
- Volunteers
- 211 people
- Sponsor
- National University Hospital, Singapore
Mild Cognitive Impairment, The Cognitive Normal Elderly
The Effects of Multidomain Non-pharmacological Interventions on the Elderly With or Without Mild Cognitive Impairment
The study aiming to investigate the efficacy, safety, and potential mechanism of a multimodal intervention on cognitive function in individuals with MCI or the cognitive normal elderly living in a community.
- Trial name
- NCT05483790
- Testing
- the multimodal intervention
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Postoperative Delirium
Protocol for Observational Study of Post op Delirium Following Total Joint Arthroplasties
The incidence of post-operative delirium in the South-east Asian population is not known. Through a prospective, single centre, observational study, the investigators aim to characterize the incidence and risk factors of delirium…
- Trial name
- NCT03260218
- Where
- Singapore
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Multiple Myeloma in Relapse
Subcutaneous Talquetamab in Elderly Patients With Multiple Myeloma in Early Relapse
Induction therapy approaches in recent years have evolved, now utilizing triple or quadruple drug regimens in the majority of patients.
- Trial name
- NCT06827860
- Testing
- Talquetamab, Daratumumab
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Larysa Sanchez
Influenza, Human
The Celljuvant Study: A Phase 3 Immunogenicity and Safety Study of aQIVc Vaccine in Adults Aged 50 Years and Older
This is a Phase 3, randomized, parallel-group, comparator-controlled, observer-blind, multicenter study of immunogenicity and safety in approximately 7700 male and female adults aged 50 years and older (approximately equally…
- Trial name
- NCT06015282
- Testing
- Investigational aQIVc, licensed QIVr, licensed aQIV
- Where
- 96 sites in United States, Canada and 6 more
- Volunteers
- 7,741 people, healthy volunteers welcome
- Sponsor
- Seqirus
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